CAS 126-07-8

Griseofulvina

Descripción:

Griseofulvina es un medicamento antifúngico que se utiliza principalmente para tratar infecciones por dermatofitos, particularmente aquellas que afectan la piel, el cabello y las uñas. Se deriva del moho Penicillium griseofulvum y funciona inhibiendo la mitosis de las células fúngicas, evitando así el crecimiento y la reproducción de hongos. Griseofulvina se caracteriza por su estructura cristalina y se administra típicamente por vía oral. Es poco soluble en agua pero más soluble en disolventes orgánicos, lo que influye en su absorción y biodisponibilidad. La sustancia es conocida por su vida media relativamente larga, lo que permite una dosificación una vez al día en muchos casos. Los efectos secundarios comunes pueden incluir trastornos gastrointestinales, dolor de cabeza y posibles reacciones alérgicas. Griseofulvina está contraindicado en ciertas poblaciones, como las personas embarazadas, debido a posibles efectos teratogénicos. Su efectividad a menudo se evalúa a través de la evaluación clínica y pruebas de laboratorio para confirmar la presencia de especies fúngicas susceptibles. En general, Griseofulvina sigue siendo una opción terapéutica significativa en el manejo de infecciones fúngicas específicas.

Fórmula: C₁₇H₁₇ClO₆

InChI: InChI=1/C17H19ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h7-8,12H,5-6H2,1-4H3/t8-,12?,17+/m1/s1

Clave InChI: InChIKey=DDUHZTYCFQRHIY-RBHXEPJQSA-N

SMILES: O=C1[C@@]2(OC=3C1=C(OC)C=C(OC)C3Cl)C(OC)=CC(=O)C[C@H]2C

Sinónimos:

• (1′S,6′R)-7-Chloro-2′,4,6-trimethoxy-6′-methylspiro[benzofuran-2(3H),1′-[2]cyclohexene]-3,4′-dione
• (2R,6'S)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione
• (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione
• (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohexane]-3,4'-dione
• (2S,6'S)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione
• 7-Chloro-2',4,6-trimethoxy-6'-methylspiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione
• 7-Chloro-2',4,6-trimethoxy-6'β-methylspiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione
• 7-Chloro-2′,4,6-trimethoxy-6′β-methylspiro[benzofuran-2(3H),1′-[2]cyclohexene]-3,4′-dione
• 7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione
• Amudane
• Curling factor
• Fulcin
• Fulvicin
• Fulvicin Bolus
• Fulvicin P/G
• Fulvicin U/F
• Fulvidex
• Fulvina
• Fulvinil
• Fulvistatin
• Gricin
• Grifulin
• Grifulvin
• Grifulvin V
• Gris-PEG
• Grisactin
• Grisefulin
• Griseofulvin Powder
• Griseofulvina
• Griseofulvine
• Griseovin
• Grisofulvin
• Grisovin
• Grisovin FP
• Grysio
• Idifulvin
• Lamoryl
• Likuden
• Neo-Fulcin
• Polygris
• Poncyl
• Poncyl FP
• Spiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione, 7-chloro-2',4,6-trimethoxy-6'-methyl-, (1'S,6'R)-
• Spiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione, 7-chloro-2',4,6-trimethoxy-6'-methyl-, (1'S-trans)-
• Spiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione, 7-chloro-2',4,6-trimethoxy-6'β-methyl-
• Spiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione,7-chloro-2',4,6-trimethoxy-6'-methyl-, (1'R-trans)-
• Spiro[benzofuran-2(3H),1′-[2]cyclohexene]-3,4′-dione, 7-chloro-2′,4,6-trimethoxy-6′-methyl-, (1′S,6′R)-
• Spiro[benzofuran-2(3H),1′-[2]cyclohexene]-3,4′-dione, 7-chloro-2′,4,6-trimethoxy-6′-methyl-, (1′S-trans)-
• Spiro[benzofuran-2(3H),1′-[2]cyclohexene]-3,4′-dione, 7-chloro-2′,4,6-trimethoxy-6′β-methyl-
• Spirofulvin
• Sporostatin
• Xuanjing
• (+)-Griseofulvin
• 7-CHLORO-2',4,6-TRIMETHOXY-6'-METHYL-, (1'S-TRANS)-SPIRO(BENZOFURAN-2(3H),1'-(2)CYCLOHEXENE)-3,4'-DIONE
• (2s-trans)-7-chloro-2’,4,6-trimethoxy-6’-methylspiro[benzofuran-2(3h),1’-[2]cy
• (2S)-TRANS-7-CHLORO-2',4,6-TRIMETHOXY-6'-METHYLSPIRO(BENZOFURAN-2[3H],1'-[2]CYCLOHEXENE)-3,4'-DIONE
• Delmofulvina
• (2s-trans)-xy-6’-methyl
• 7-chloro-4,6,2’-trimethoxy-6’-methylgris-2’-en-3,4’-dione
• curlingfactor
• 7-Chloro-2',4,6-trimethoxy-6'beta-methylspiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione
• [2S-TRANS]-7-CHLORO-2,4,6-TRIMETHOXY-6'-METHYLSPIRO[BENZOFURAN-2(3H), 1'(2)-CYCLOHEXANE]-3,4'-DIONE
• (+)-griseofulvi
• -6’-beta-methyl-
• 7-Chloro-4,6,2'-trimethoxy-6'-methylgris-2'-en-3,4'-dione
• 2’-en-4’-one)
• clohexene]-3,4’-dione
• 6-dimethoxycoumaran-3-one-2-spiro-1’-(2’-methoxy-6’-methylcyclohex-7-chloro-

(+)-Griseofulvin

CAS: 126-07-8

Fórmula: C₁₇H₁₇ClO₆

Pureza: >95.0%(HPLC)(qNMR)

Forma y color: White to Almost white powder to crystal

Peso molecular: 352.77

Ref: 3B-G0384

(+)-Griseofulvin, 97%

CAS: 126-07-8

Griseofulvin is an antifungal drug. It is used both in animal and in humans, to treat ringworm infections of the skin and nails. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy br

Fórmula: C₁₇H₁₉ClO₆

Pureza: 97%

Forma y color: White, Powder

Peso molecular: 354.78

Ref: 02-B23521

Griseofulvin

CAS: 126-07-8

Fórmula: C₁₇H₁₇ClO₆

Pureza: 99.11%

Forma y color: Brownish. Powder

Peso molecular: 353.0

Ref: 8R-CL0363

Griseofulvin

CAS: 126-07-8

Forma y color: Neat

Ref: 61-FOR0582.00

GRISEOFULVIN RS

CAS: 126-07-8

GRISEOFULVIN RS

Fórmula: C₁₇H₁₇ClO₆

Peso molecular: 352.7663

Ref: 41-ICRS0322

Griseofulvin

CAS: 126-07-8

Antibiotics nesoi

Fórmula: C₁₇H₁₇ClO₆

Forma y color: White Cream Powder

Peso molecular: 352.07137

Ref: 45-1299007

Griseofulvin Permeability Diameter

CAS: 126-07-8

Antibiotics nesoi

Fórmula: C₁₇H₁₇ClO₆

Forma y color: White Off-White Powder

Peso molecular: 352.77

Ref: 45-1299200

(2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H-spiro[1-benzofuran-2,1'-cyclohexan]-2'-ene-3,4'-dione

CAS: 126-07-8

Fórmula: C₁₇H₁₇ClO₆

Pureza: 95%

Forma y color: Solid

Peso molecular: 352.7663

Ref: IN-DA0032AV

Griseofulvin

CAS: 126-07-8

Griseofulvin (Fulvicin) is an antifungal agent used in the treatment of TINEA infections.

Fórmula: C₁₇H₁₇ClO₆

Pureza: 97.06% - 98.12%

Forma y color: Stout Octahedra Or Rhombs From Benzene

Peso molecular: 352.77

Ref: TM-T1382

Griseofulvin

CAS: 126-07-8

Griseofulvin

Pureza: ≥95%

Peso molecular: 352.77g/mol

Ref: 54-BUP18502

Griseofulvin

CAS: 126-07-8

Fórmula: C₁₇H₁₇ClO₆

Forma y color: White To Off-White Solid

Peso molecular: 352.77

Ref: 4Z-G-082

Griseofulvin, EP grade

CAS: 126-07-8

Fórmula: C₁₇H₁₇ClO₆

Pureza: ≤ 0.75%

Forma y color: White or pale yellow powder

Peso molecular: 352.77

Ref: 7W-GA3498

Griseofulvin-13C-d3

CAS: 126-07-8

Fórmula: C₁₆₁₃CH₁₄D₃ClO₆

Forma y color: White To Off-White Solid

Peso molecular: 356.78

Ref: 4Z-G-088

Griseofulvin

CAS: 126-07-8

Fórmula: C₁₇H₁₇ClO₆

Pureza: 97.0 - 102.0 % (dried basis)

Forma y color: White or off-white powder

Peso molecular: 352.77

Ref: 7W-GA6599

(+)-Griseofulvin

CAS: 126-07-8

(+)-Griseofulvin

Pureza: 98%

Peso molecular: 352.77g/mol

Ref: 54-OR1029322

Griseofulvin

Producto controlado

CAS: 126-07-8

Fórmula: C₁₇H₁₇ClO₆

Forma y color: Neat

Peso molecular: 352.77

Ref: 04-C14056500

Griseofulvin

Producto controlado

CAS: 126-07-8

Fórmula: C₁₇H₁₇ClO₆

Forma y color: Off-White

Peso molecular: 352.77

Ref: 86-MM0582.00

Griseofulvin 100 µg/mL in Acetonitrile

CAS: 126-07-8

Fórmula: C₁₇H₁₇ClO₆

Forma y color: Single Solution

Peso molecular: 352.77

Ref: 04-V14056500AL-100

Griseofulvin

Producto controlado

CAS: 126-07-8

Applications It is an antifungal drug. It is used both in animal and in humans, to treat rigworm infections of the skin and nails. It is derived from the mold Penicillium griseofulvum.Environmental contaminants; Food contaminants
References Oxford, et al.: Biochem. J., 33, 240 (1939), Townley, E.R., et al.: Anal. Profiles Drug Subs., 8, 219 (1979),

Fórmula: C₁₇H₁₇ClO₆

Forma y color: Off-White

Peso molecular: 352.77

Ref: TR-G787500

Griseofulvin

CAS: 126-07-8

Anti-fungal; microtubule polymerization inhibitor

Fórmula: C₁₇H₁₇ClO₆

Pureza: Min. 97 Area-%

Forma y color: Powder

Peso molecular: 352.77 g/mol

Ref: 3D-FG23704