CAS 1401-69-0

Tilosina

Descripción:

Tilosina es un antibiótico macrólido utilizado principalmente en medicina veterinaria, particularmente para ganado y aves de corral, para tratar infecciones bacterianas y promover el crecimiento. Se deriva de la bacteria *Streptomyces fradiae* y exhibe un amplio espectro de actividad contra bacterias Gram-positivas y algunas Gram-negativas. Tilosina funciona inhibiendo la síntesis de proteínas en las bacterias, evitando así su crecimiento y reproducción. La sustancia se administra típicamente en forma de su sal de tartrato, que mejora su solubilidad. Tilosina es conocido por su relativamente baja toxicidad en animales, pero su uso está regulado en animales productores de alimentos para prevenir residuos de antibióticos en productos cárnicos. Además, se ha estudiado por sus posibles aplicaciones en acuicultura y como aditivo alimentario. Su estructura química presenta un gran anillo de lactona, característico de los macrólidos, que contribuye a sus propiedades antibacterianas. Al igual que con muchos antibióticos, la aparición de resistencia es una preocupación, lo que requiere una gestión cuidadosa de su uso en prácticas agrícolas.

Fórmula: C₄₆H₇₇NO₁₇

InChI: InChI=1S/C46H77NO17/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3/b15-14+,23-18+/t24-,25+,26-,27-,28+,29+,30-,32-,33-,35+,36-,37-,38-,39-,40-,41-,42-,43+,44+,45-,46-/m1/s1

Clave InChI: InChIKey=WBPYTXDJUQJLPQ-VMXQISHHSA-N

SMILES: O([C@H]1[C@H](N(C)C)[C@@H](O)[C@H](O[C@H]2[C@@H](CC=O)C[C@@H](C)C(=O)/C=C/C(/C)=C/[C@H](CO[C@H]3[C@H](OC)[C@H](OC)[C@H](O)[C@@H](C)O3)[C@@H](CC)OC(=O)C[C@@H](O)[C@@H]2C)O[C@@H]1C)[C@H]4C[C@@](C)(O)[C@@H](O)[C@H](C)O4

Sinónimos:

• Fradizine
• Oxacyclohexadeca-11,13-diene-7-acetaldehyde, 15-[[(6-deoxy-2,3-di-O-methyl-β-<span class="text-smallcaps">D</smallcap>-allopyranosyl)oxy]methyl]-6-[[3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-α-<smallcap>L</smallcap>-ribo-hexopyranosyl)-3-(dimethylamino)-β-<smallcap>D</span>-glucopyranosyl]oxy]-16-ethyl-4-hydroxy-5,9,13-trimethyl-2,10-dioxo-, [4R-(4R*,5S*,6S*,7R*,9R*,11E,13E,15R*,16R*)]-
• Oxacyclohexadeca-11,13-diene-7-acetaldehyde, 15-[[(6-deoxy-2,3-di-O-methyl-β-D-allopyranosyl)oxy]methyl]-6-[[3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-3-(dimethylamino)-β-D-glucopyranosyl]oxy]-16-ethyl-4-hydroxy-5,9,13-trimethyl-2,10-dioxo-, [4R-(4R*,5S*,6S*,7R*,9R*,11E,13E,15R*,16R*)]-
• Oxacyclohexadecane, tylosin deriv.
• Tilan
• Tilosina
• Tylocine
• Tylosin A
• Tylosin base
• Tylosine
• Vubityl 200
• [(2R,3R,4E,6E,9R,11R,12S,13S,14R)-12-{[3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl)-3-(dimethylamino)-beta-D-glucopyranosyl]oxy}-2-ethyl-14-hydroxy-5,9,13-trimethyl-8,16-dioxo-11-(2-oxoethyl)oxacyclohexadeca-4,6-dien-3-yl]methyl 6-deoxy-2,3-di-O-methyl-beta-D-allopyranoside
• [(2R,3R,4E,6E,9R,11R,12S,13S,14R)-12-{[3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-3-(dimethylamino)-β-D-galactopyranosyl]oxy}-2-ethyl-14-hydroxy-5,9,13-trimethyl-8,16-dioxo-11-(2-oxoethyl)oxacyclohexadeca-4,6-dien-3-yl]methyl 6-deoxy-2,3-di-O-methyl-D-allopyranoside
• [(2R,4E,6E,9R,11R,12S,13S,14R)-12-{[3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl)-3-(dimethylamino)-beta-D-glucopyranosyl]oxy}-2-ethyl-14-hydroxy-5,9,13-trimethyl-8,16-dioxo-11-(2-oxoethyl)oxacyclohexadeca-4,6-dien-3-yl]methyl 6-deoxy-2,3-di-O-methyl-beta-D-allopyranoside
• [(2R,4E,6E,9R,11R,12S,14R)-12-{[3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-3-(dimethylamino)-β-D-glucopyranosyl]oxy}-2-ethyl-14-hydroxy-5,9,13-trimethyl-8,16-dioxo-11-(2-oxoethyl)oxacyclohexadeca-4,6-dien-3-yl]methyl 6-deoxy-2,3-di-O-methyl-D-allopyranoside
• [4R-(4R*,5S*,6S*,7R*,9R*,11E,13E,15R*,16R*)]-15-[[(6-Deoxy-2,3-di-O-methyl-β-<span class="text-smallcaps">D</smallcap>-allopyranosyl)oxy]methyl]-6-[[3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-α-<smallcap>L</smallcap>-ribo-hexopyranosyl)-3-(dimethylamino)-β-<smallcap>D</span>-glucopyranosyl]oxy]-16-ethyl-4-hydroxy-5,9,13-trimethyl-2,10-dioxooxacyclohexadeca-11,13-diene-7-acetaldehyde
• [4R-(4R*,5S*,6S*,7R*,9R*,11E,13E,15R*,16R*)]-15-[[(6-Deoxy-2,3-di-O-methyl-β-D-allopyranosyl)oxy]methyl]-6-[[3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-3-(dimethylamino)-β-D-glucopyranosyl]oxy]-16-ethyl-4-hydroxy-5,9,13-trimethyl-2,10-dioxooxacyclohexadeca-11,13-diene-7-acetaldehyde

Tylosin

CAS: 1401-69-0

Tylosin

Forma y color: Off-White

Ref: 47-349

TYLOSIN CRS

CAS: 1401-69-0

TYLOSIN CRS

Fórmula: C₄₆H₇₇NO₁₇

Peso molecular: 916.1001

Ref: 41-T2880000

FIRST INTERNATIONAL STANDARD FOR TYLOSIN

CAS: 1401-69-0

FIRST INTERNATIONAL STANDARD FOR TYLOSIN

Fórmula: C₄₆H₇₇NO₁₇

Peso molecular: 916.1001

Ref: 41-ISA_TYN

Tylosin

CAS: 1401-69-0

Antibiotics nesoi

Fórmula: C₄₆H₇₇NO₁₇

Forma y color: White Off-White Yellow Powder

Peso molecular: 916.1 g/mol

Ref: 45-1703805

Tylosin

CAS: 1401-69-0

Fórmula: C₄₆H₇₇NO₁₇

Pureza: 80%

Forma y color: Solid

Peso molecular: 916.1001

Ref: IN-DA00HVQN

Tylosin

CAS: 1401-69-0

Tylosin

Pureza: mixture

Peso molecular: 916.1g/mol

Ref: 54-BUP14011

Tylosin

CAS: 1401-69-0

Tylosin (Tylosine) is a macrolide antibiotic obtained from cultures of Streptomyces fradiae.

Fórmula: C₄₆H₇₇NO₁₇

Pureza: mixture - mixture

Forma y color: Coa

Peso molecular: 916.10

Ref: TM-T1003

Tylosin

CAS: 1401-69-0

Tylosin

Pureza: 93%

Peso molecular: 916.1g/mol

Ref: 54-OR1029875

Tylosin

CAS: 1401-69-0

Fórmula: C₄₆H₇₇NO₁₇

Pureza: ≥ 900IU/mg

Forma y color: White, almost white or pale yellow powder

Peso molecular: 916.10

Ref: 7W-GA0812

Tylosin-d3

CAS: 1401-69-0

Fórmula: C₄₆H₇₄D₃NO₁₇

Peso molecular: 919.14

Ref: 4Z-T-175002

Tylosin

CAS: 1401-69-0, 8026-48-0

Fórmula: C₄₆H₇₇NO₁₇

Forma y color: White To Off-White Solid

Peso molecular: 916.12

Ref: 4Z-T-175001

Tylosin A 100 µg/mL in Acetonitrile

CAS: 1401-69-0

Fórmula: C₄₆H₇₇NO₁₇

Forma y color: Single Solution

Peso molecular: 916.10

Ref: 04-A17895615AL-100

GB 31660.1-2019 Macrolide Antibiotics Mixture 167 100 µg/mL in Methanol

Producto controlado

CAS: 114-07-8, 1401-69-0, 16846-24-5, 2751-09-9, 69-23-8, 8025-81-8, 81103-11-9, 83905-01-5, 93952-07-9

Forma y color: Mixture

Ref: 04-A50000167ME

Tylosin-d3 (100 Mug/mL in Methanol)

CAS: 1401-69-0

Fórmula: C₄₆H₇₄D₃NO₁₇

Forma y color: Colourless

Peso molecular: 916.10

Ref: TR-KIT9112

Tylosin-d3

Producto controlado

CAS: 1401-69-0

Applications Labelled Tylosin (T947650). Tylosin is a macrolide antibiotic isolated from a strain of Streptomycetes fradiae found in soil from Thailand. Antibacterial.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hamill, et al.: Antibiot. Chemother., 11, 328 (1961), Corcoran, J.W., et al.: J. Antibiot., 30, 1012 (1977), Seno, E.T., et al.: Antimicrob. Agents. Chemother., 11, 455 (1977),

Fórmula: C₄₆H₇₄D₃NO₁₇

Forma y color: Neat

Peso molecular: 916.10

Ref: TR-T947652

Tylosin

CAS: 1401-69-0

Stability Light Sensitive
Applications Tylosin is a macrolide antibiotic isolated from a strain of Streptomycetes fradiae found in soil from Thailand. Antibacterial. This compound is a contaminant of emerging concern (CECs).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hamill, et al.: Antibiot. Chemother., 11, 328 (1961), Corcoran, J.W., et al.: J. Antibiot., 30, 1012 (1977), Seno, E.T., et al.: Antimicrob. Agents. Chemother., 11, 455 (1977),

Fórmula: C₄₆H₇₇NO₁₇

Forma y color: Off-White

Peso molecular: 916.10

Ref: TR-T947650

Tylosin

CAS: 1401-69-0

Pureza: 93%+;RG

Peso molecular: 916.1119995

Ref: 10-F951543