CAS: 171179-06-9 - N~4~-(3-bromophenyl)-N~6~-methylpyrido[3,4-d]pyrimidine-4,6-diamine

Fórmula: C₁₄H₁₂BrN₅

InChI: InChI=1S/C14H12BrN5/c1-16-13-6-11-12(7-17-13)18-8-19-14(11)20-10-4-2-3-9(15)5-10/h2-8H,1H3,(H,16,17)(H,18,19,20)

Clave InChI: InChIKey=KFHMLBXBRCITHF-UHFFFAOYSA-N

SMILES: BrC1=CC=CC(=C1)NC=2N=CN=C3C=NC(=CC32)NC

Sinónimos:

• N4-(3-bromophenyl)-N6-methylpyrido[3,4-d]pyrimidine-4,6-diamine
• N⁴-(3-Bromophenyl)-N⁶-methylpyrido[3,4-d]pyrimidine-4,6-diamine
• Pd 158780
• Pyrido[3,4-d]pyrimidine-4,6-diamine, N4-(3-bromophenyl)-N6-methyl-
• Pyrido[3,4-d]pyrimidine-4,6-diamine, N⁴-(3-bromophenyl)-N⁶-methyl-
• Pyrido[3,4-d]pyrimidine-4,6-diamine, N~4~-(3-bromophenyl)-N~6~-methyl-
• T66 Bn Dn Inj Emr Ce& Hm1 [Wln]

PD158780

CAS: 171179-06-9

• Fórmula: C₁₄H₁₂BrN₅
• Pureza: 98%
• Forma y color: Solid
• Peso molecular: 330.1826

PD 158780

CAS: 171179-06-9

• Fórmula: C₁₄H₁₂BrN₅
• Pureza: >97.0%(HPLC)
• Forma y color: White to Yellow to Green powder to crystal
• Peso molecular: 330.19

PD158780

CAS: 171179-06-9

PD 158780 blocks all ErbB receptors: EGFR, ErbB2-4, with IC50s: 8μM, 49-52 nM.

• Fórmula: C₁₄H₁₂BrN₅
• Pureza: 98.81%
• Forma y color: Solid
• Peso molecular: 330.18

PD 158780

CAS: 171179-06-9

EGFR tyrosine kinase inhibitor; anti-proliferative

• Fórmula: C₁₄H₁₂BrN₅
• Pureza: Min. 95%
• Peso molecular: 330.18 g/mol