CAS 83905-01-5

Azitromicina

Descripción:

Azitromicina es un antibiótico macrólido caracterizado por su actividad de amplio espectro contra diversas infecciones bacterianas. Se deriva de la eritromicina y es conocido por su estructura única, que incluye un gran anillo de lactona y varios moieties de azúcar. Azitromicina se administra típicamente por vía oral y es notable por su vida media prolongada, lo que permite una dosificación una vez al día y cursos de tratamiento más cortos en comparación con otros antibióticos. Actúa inhibiendo la síntesis de proteínas bacterianas al unirse a la subunidad ribosomal 50S, previniendo efectivamente el crecimiento de bacterias. Azitromicina es eficaz contra una variedad de patógenos, incluidos aquellos responsables de infecciones respiratorias, infecciones cutáneas y enfermedades de transmisión sexual. Generalmente es bien tolerado, con efectos secundarios comunes que incluyen trastornos gastrointestinales. Además, tiene propiedades antiinflamatorias, que pueden ser beneficiosas en el tratamiento de ciertas condiciones más allá de las infecciones bacterianas. Su farmacocinética, que incluye una buena penetración en los tejidos y acumulación en las células, contribuye a su eficacia en el tratamiento de infecciones. Azitromicina también se incluye en regímenes de tratamiento para ciertas infecciones atípicas y a menudo se utiliza en terapias combinadas.

Fórmula: C₃₈H₇₂N₂O₁₂

InChI: InChI=1S/C38H72N2O12/c1-15-27-38(10,46)31(42)24(6)40(13)19-20(2)17-36(8,45)33(52-35-29(41)26(39(11)12)16-21(3)48-35)22(4)30(23(5)34(44)50-27)51-28-18-37(9,47-14)32(43)25(7)49-28/h20-33,35,41-43,45-46H,15-19H2,1-14H3/t20-,21-,22+,23-,24-,25+,26+,27-,28+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1

Clave InChI: InChIKey=MQTOSJVFKKJCRP-BICOPXKESA-N

SMILES: O([C@@H]1[C@@H](C)[C@H](O[C@H]2C[C@](OC)(C)[C@@H](O)[C@H](C)O2)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)N(C)C[C@H](C)C[C@@]1(C)O)[C@H]3[C@H](O)[C@@H](N(C)C)C[C@@H](C)O3

Sinónimos:

• (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-<span class="text-smallcaps">L</smallcap>-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-<smallcap>D</span>-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one
• (2R,3S,4R,5S,6R,8R,11S,12R,13R,14S)-5-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-14-ethyl-6,12,13-trihydroxy-3-[(2S,4R,5S,6R)-5-hydroxy-4-methoxy-4,6-dimethyl-tetrahydropyran-2-yl]oxy-2,4,6,8,10,11,13-heptamethyl-15-oxa-10-azacyclopentadecan-1-one
• 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-<span class="text-smallcaps">L</smallcap>-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-<smallcap>D</span>-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-
• 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-<span class="text-smallcaps">L</smallcap>-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-<smallcap>D</span>-xylo-hexopyranosyl]oxy]-, [2R-(2R*,3S*,4R*,5R*,8R*,10R*,11R*,12S*,13S*,14R*)]-
• 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-
• 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, [2R-(2R*,3S*,4R*,5R*,8R*,10R*,11R*,12S*,13S*,14R*)]-
• 1-Oxa-6-azacyclopentadecan-15-one,13-((2,6-dideoxy-3-C-methyl-1-3-O-methyl-alpha-L-ribo-hexopyranosyl)-oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)
• 11-(4-Dimethylamino-3-Hydroxy-6-Methyl-Oxan-2-Yl)Oxy-2-Ethyl-3,4,10-Tr
• 9-Deoxo-9-methyl-9a-aza-9-homoerythromycin A
• 9-Deoxo-9a-methyl-9a-aza-9a-homoetrythromycin A
• 9-deoxo-9a-methyl-9a-aza-homoerythromycin A
• Aruzilina
• Arzomicin
• Auricin
• Auricin (polyketide antibiotic)
• AzaSite
• Azadose
• Azatril
• Azee
• Azenil
• Azimin
• Aziromycin
• Azisara
• Azithral
• Azithrocin
• Azithromycin A
• Azithromycine
• Azitrocin
• Azitromax
• Aziwin
• Aziwok
• Azomycin
• Azomycin (macrolide)
• Aztrin
• Cp 62993
• Durasite
• Hemomycin
• Macromycin
• Macrozit
• N-methyl-11-aza-10-deoxo-10-dihydroerythromycin A
• Sanhe
• Setron
• Shimen
• Sumamed
• Sumazid
• Tobil
• Tridosil
• Tromix
• Trozocina
• Ultreon
• Xithron
• Xithrone
• Xz 405
• Xz 450
• Zeto
• Zi-Factor
• Zifin
• Zistic
• Zithromac
• Zithromax
• Zithromax IV
• Zitrim
• Zitrocin
• Zitromax
• Zythromax

Azithromycin

CAS: 83905-01-5

Azithromycin

Fórmula: C₃₈H₇₂N₂O₁₂

Pureza: By hplc: 97.7% by area (Typical Value in Batch COA)

Forma y color: White Solid-Powder

Peso molecular: 748.98448

Ref: 54-BIA0165

1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-

CAS: 83905-01-5

Fórmula: C₃₈H₇₆N₂O₁₄

Pureza: 98%

Forma y color: Solid

Peso molecular: 785.0150

Ref: IN-DA0036GY

Azithromycin

CAS: 83905-01-5

Fórmula: C₃₈H₇₂N₂O₁₂

Forma y color: White To Off-White Solid

Peso molecular: 749.00

Ref: 4Z-A-2617

Azithromycin

CAS: 83905-01-5

Azithromycin

Fórmula: C₃₈H₇₂N₂O₁₂

Pureza: ≥98%

Peso molecular: 748.98

Ref: 54-BUP15115

Azithromycin

Producto controlado

CAS: 83905-01-5

Fórmula: C₃₈H₇₂N₂O₁₂

Forma y color: Neat

Peso molecular: 748.98

Ref: 86-MM1075.00

Azithromycin

CAS: 83905-01-5

Fórmula: C₃₈H₇₂N₂O₁₂

Forma y color: White To Off-White

Peso molecular: 748.98

Ref: 61-FOR1075.00

Azithromycin

Producto controlado

CAS: 83905-01-5

Fórmula: C₃₈H₇₂N₂O₁₂

Forma y color: Neat

Peso molecular: 748.98

Ref: 04-C10385990

GB 31660.1-2019 Macrolide Antibiotics Mixture 167 100 µg/mL in Methanol

Producto controlado

CAS: 114-07-8, 1401-69-0, 16846-24-5, 2751-09-9, 69-23-8, 8025-81-8, 81103-11-9, 83905-01-5, 93952-07-9

Forma y color: Mixture

Ref: 04-A50000167ME

Azithromycin-d5

Producto controlado

CAS: 83905-01-5

Applications Azithromycin-d5, is the labeled analogue Azithromycin (A927000), a semi-synthetic macrolide antibiotic; related to Erythromycin A. Antibacterial.
References Langtry, H.D., et al.: Drugs, 56, 273 (1998),

Fórmula: C₃₈H₆₇D₅N₂O₁₂

Forma y color: Neat

Peso molecular: 754.02

Ref: TR-A927004

Azithromycin

CAS: 83905-01-5

Applications Azithromycin is an azalide macrolide antibiotic.
References Hunter, R., et al.: J. Vet. Pharmacol. Ther., 26, 117 (2003);

Fórmula: C₃₈H₇₂N₂O₁₂

Forma y color: Neat

Peso molecular: 748.98

Ref: TR-A927018

Azithromycin-13CD3

Producto controlado

CAS: 83905-01-5

Applications Labelled Azithromycin, a semi-synthetic macrolide antibiotic; related to Erythromycin A. Antibacterial.
References Langtry, H.D., et al.: Drugs, 56, 273 (1998),

Fórmula: C₃₇₁₃CH₆₉D₃N₂O₁₂

Forma y color: Neat

Peso molecular: 753

Ref: TR-A927003

Azithromycin

CAS: 83905-01-5

Azithromycin (CP 62993) is a macrolide antibiotic that primarily targets the 50S subunit of bacterial ribosomes. High-Quality, Low-Cost!

Fórmula: C₃₈H₇₂N₂O₁₂

Pureza: 99.9% - 99.97%

Forma y color: White To Off-White Solid Crystalline

Peso molecular: 748.98

Ref: TM-T6401

Azithromycin

CAS: 83905-01-5

Fórmula: C₃₈H₇₂N₂O₁₂

Peso molecular: 749

Ref: ST-EA-CP-A37000

Azithromycin

CAS: 83905-01-5

A broad-spectrum antibiotic of macrolide class which targets 50S ribosome subunit and inhibits protein synthesis. Azithromycin is a semi-synthetic acid-stable derivative of erythromycin. In vitro, azithromycin is more efficient than erythromycin in some Gram-negative organisms such as Haemophilus influenzae, Haemophilus parainfluenzae, Moraxella catarrhalis, Neisseria gonorrhoeae and Borrelia burgdorferi.

Fórmula: C₃₈H₇₂N₂O₁₂

Pureza: 945.0 To 1030.0 U/Mg

Forma y color: White Powder

Peso molecular: 748.98 g/mol

Ref: 3D-AD29657

Azithromycin in Methanol

CAS: 83905-01-5

Methanol

Fórmula: C₃₈H₇₂N₂O₁₂

Forma y color: Solid

Peso molecular: 749.0

Ref: BE-BePure-20495XM-100

Azithromycin in Methanol

CAS: 83905-01-5

Methanol

Fórmula: C₃₈H₇₂N₂O₁₂

Forma y color: Solid

Peso molecular: 749.0

Ref: BE-BePure-20495YM-1000

Azithromycin-d5 (major) in Methanol

CAS: 83905-01-5

Methanol

Fórmula: C₃₈H₇₂N₂O₁₂

Forma y color: Solid

Peso molecular: 749.0

Ref: BE-BePure-22930XM-100

Azithromycin Solution Reference Material in Methanol

CAS: 83905-01-5

Fórmula: C₃₈H₇₂N₂O₁₂

Forma y color: Solid

Peso molecular: 749.0

Ref: BE-GRGT-GBW(E)085529-1000

Azithromycin

CAS: 83905-01-5

Fórmula: C₃₈H₇₂N₂O₁₂

Forma y color: Solid

Peso molecular: 749.0

Ref: BE-BePure-20495

Azithromycin

CAS: 83905-01-5

Fórmula: C₃₈H₇₂N₂O₁₂

Forma y color: Solid

Peso molecular: 749.0

Ref: BE-RMCA361000