EGFR
Los inhibidores del receptor del factor de crecimiento epidérmico (EGFR) son compuestos que bloquean la señalización del EGFR, un receptor que a menudo está sobreexpresado en varios tipos de cáncer y que juega un papel crucial en la angiogénesis. Los inhibidores del EGFR se utilizan para prevenir el crecimiento tumoral y las metástasis al interrumpir las vías que promueven la formación de vasos sanguíneos en los tumores. Estos inhibidores son ampliamente utilizados en la investigación y terapia contra el cáncer. En CymitQuimica, ofrecemos una amplia selección de inhibidores de EGFR de alta calidad para apoyar su investigación en oncología y angiogénesis.
Se han encontrado 572 productos de "EGFR"
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Canertinib
CAS:Fórmula:C24H25ClFN5O3Pureza:>98.0%(HPLC)(qNMR)Forma y color:White to Light yellow powder to crystalPeso molecular:485.94CL-387785
CAS:Fórmula:C18H13BrN4OPureza:>98.0%(GC)Forma y color:White to Light yellow powder to crystalPeso molecular:381.23(3S,4S)-PF-06459988
CAS:<p>(3S, 4S)-PF-06459988, a less active S enantiomer, specifically inhibits T790M mutant EGFR with high selectivity.</p>Fórmula:C19H22ClN7O3Forma y color:SolidPeso molecular:431.88BMS-599626
CAS:Fórmula:C27H27FN8O3Pureza:>98.0%(HPLC)Forma y color:White to Light yellow to Light orange powder to crystalPeso molecular:530.56Erlotinib-d6
CAS:<p>Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR. Erlotinib D6 is a deuterium labeled Erlotinib .</p>Fórmula:C22H23N3O4Pureza:98%Forma y color:SolidPeso molecular:399.47AG 1478 Hydrochloride
CAS:Fórmula:C16H14ClN3O2·HClPureza:>95.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:352.22EGFR Protein, Human, Recombinant (His & Avi), Biotinylated
<p>EGFR Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.</p>Forma y color:Lyophilized PowderPeso molecular:71.5 kDa (predicted). Due to glycosylation, the protein migrates to 90-120 kDa based on Tris-Bis PAGE result.Hypericin
CAS:Fórmula:C30H16O8Pureza:>95.0%(HPLC)Forma y color:Black powder to crystalPeso molecular:504.45Rociletinib hydrobromide
CAS:<p>Rociletinib hydrobromide is an orally delivered inhibitor of the mutant form of EGFR kinase (Kis: 21.5 nM and 303.3 nM for EGFR L858R/T790M and EGFR WT).</p>Fórmula:C27H29BrF3N7O3Pureza:98%Forma y color:SolidPeso molecular:636.46Osimertinib dimesylate
CAS:<p>Osimertinib dimesylate is an irreversible and mutant selective EGFR inhibitor (IC50s: 12 and 1 nM against EGFR L858R and EGFR L858R/T790M).</p>Fórmula:C30H41N7O8S2Pureza:98%Forma y color:SolidPeso molecular:691.82Mavelertinib
CAS:<p>Mavelertinib (PF-06747775) is an EGFR tyrosine kinase (EGFR TKI) inhibitor that inhibits T790M/L858R and can be used to study tumours.</p>Fórmula:C18H22FN9O2Pureza:99.89%Forma y color:SolidPeso molecular:415.42Tyrphostin AG 1478
CAS:Fórmula:C16H14ClN3O2Pureza:>98.0%(HPLC)Forma y color:Light orange to Yellow to Green powder to crystalPeso molecular:315.76WHI-P154
CAS:Fórmula:C16H14BrN3O3Pureza:>98.0%(HPLC)Forma y color:White to Yellow to Orange powder to crystalPeso molecular:376.21Tucatinib hemiethanolate
CAS:<p>Tucatinib (Irbinitinib) hemiethanolate is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM.</p>Fórmula:C54H54N16O5Pureza:99.76%Forma y color:SolidPeso molecular:1007.11Mubritinib
CAS:Fórmula:C25H23F3N4O2Pureza:>98.0%(HPLC)Forma y color:White to Gray to Brown powder to crystalPeso molecular:468.48AEE 788
CAS:Fórmula:C27H32N6Pureza:>98.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:440.60BI-4142
CAS:<p>BI-4142 is a HER2 inhibitor that inhibits cancer cell proliferation, suppresses her2-dependent cell lines and inhibits downstream signalling.</p>Fórmula:C28H27N9O2Pureza:97.21% - 98.09%Forma y color:SolidPeso molecular:521.57Rilematovir
CAS:<p>Rilematovir (JNJ-678) inhibits fusion protein, has antiviral properties, low toxicity, and targets RSV treatment.</p>Fórmula:C21H20ClF3N4O3SPureza:99.82%Forma y color:SolidPeso molecular:500.92AV-412 free base
CAS:<p>AV-412 free base is an EGFR inhibitor (IC50s: 0.75, 0.79, 0.5, 2.3, 19 nM for EGFR, EGFR(T790M), EGFR(L858R), EGFR(L858R/T790M) and ErbB2).</p>Fórmula:C27H28ClFN6OForma y color:SolidPeso molecular:507PD 158780
CAS:Fórmula:C14H12BrN5Pureza:>97.0%(HPLC)Forma y color:White to Yellow to Green powder to crystalPeso molecular:330.19
