CAS: 2070014-82-1 - 2-Propenamide, N-[2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-, compd. with methanesulfonate (1:2)

Fórmula: C₂₈H₃₃N₇O₂.2CH₄O₃S

InChI: InChI=1S/C28H33N7O2.CH4O3S/c1-7-27(36)30-22-16-23(26(37-6)17-25(22)34(4)15-14-33(2)3)32-28-29-13-12-21(31-28)20-18-35(5)24-11-9-8-10-19(20)24;1-5(2,3)4/h7-13,16-18H,1,14-15H2,2-6H3,(H,30,36)(H,29,31,32);1H3,(H,2,3,4)

Clave InChI: InChIKey=FUKSNUHSJBTCFJ-UHFFFAOYSA-N

SMILES: O=C(C=C)NC1=CC(NC=2N=CC=C(N2)C3=CN(C=4C=CC=CC34)C)=C(OC)C=C1N(C)CCN(C)C.O=S(=O)(O)C

Osimertinib dimesylate

CAS: 2070014-82-1

Osimertinib dimesylate is an irreversible and mutant selective EGFR inhibitor (IC50s: 12 and 1 nM …

• Fórmula: C₃₀H₄₁N₇O₈S₂
• Pureza: 98%
• Forma y color: Solid
• Peso molecular: 691.82

Osimertinib dimesylate

CAS: 2070014-82-1

Osimertinib dimesylate is a novel oral, selective inhibitor of MET protein tyrosine kinase. It has …

• Fórmula: C₃₀H₄₁N₇O₈S₂
• Pureza: Min. 95%
• Peso molecular: 691.8 g/mol