Asociado a microtúbulos
Los inhibidores de proteínas asociadas a microtúbulos se dirigen a proteínas que interactúan con los microtúbulos, los componentes estructurales del citoesqueleto de la célula, esenciales para la división celular. Estas proteínas regulan la estabilidad y la dinámica de los microtúbulos durante la mitosis. Inhibir las proteínas asociadas a microtúbulos puede interrumpir la función de los microtúbulos, lo que lleva al arresto del ciclo celular y la apoptosis, particularmente en células cancerosas de rápida división. Estos inhibidores se utilizan ampliamente en la investigación del cáncer y el desarrollo de fármacos. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteínas asociadas a microtúbulos de alta calidad para apoyar su investigación en división celular, dinámica del citoesqueleto y terapia contra el cáncer.
Se han encontrado 283 productos de "Asociado a microtúbulos"
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MT-7
CAS:MT-7 is a tubulin polymerization inhibitor.Fórmula:C22H17N3O2Pureza:98%Forma y color:SolidPeso molecular:355.39Tubulin inhibitor 7
CAS:Tubulin inhibitor 7 is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines (tubulin polymerization (IC50: 0.52 μM), K562 cell growth (Fórmula:C21H14N2O4Pureza:98%Forma y color:SolidPeso molecular:358.35Alyssin, (R)-
CAS:Alyssin, (R)-, is an analogue of Sulforaphane that has been shown to have cytotoxic effect on CCRF-SB leukemia cells and lymphoblastoid cells.Fórmula:C7H13NOS2Forma y color:SolidPeso molecular:191.31Cemadotin hydrochloride
CAS:Cemadotin hydrochloride (LU103793) is a synthetic mitosis inhibitor derived from Dolastatin 15 for treating solid tumors.Fórmula:C35H57ClN6O5Forma y color:SolidPeso molecular:677.33Alyssin, (S)-
CAS:Alyssin, (S)-, is an analogue of Sulforaphane that has been shown to have cytotoxic effect on CCRF-SB leukemia cells and lymphoblastoid cells.Fórmula:C7H13NOS2Forma y color:SolidPeso molecular:191.31OX01914
CAS:OX01914 is a soluble modulator to increase utrophin in DMD studies, EC50 20.5 μM.Fórmula:C17H14N4OForma y color:SolidPeso molecular:290.32Denibulin HCl
CAS:Denibulin (MN-029) disrupts tumor blood vessels by inhibiting microtubule assembly, enhancing radiation and cisplatin efficacy.Fórmula:C18H20ClN5O3SForma y color:SolidPeso molecular:421.9Centmitor-1
CAS:Centmitor-1 is a novel mitotic inducer that modulates the positive end of microtubules and reduces microtubule dynamics.Fórmula:C22H16BrN3O3Forma y color:SolidPeso molecular:450.28CAY10701
CAS:CAY10701, a 7-deazahypoxanthine, impedes cell growth (GI50: 9-38 nM) while sparing normal fibroblasts (>1,500-fold), and shrinks mouse colorectal tumors.Fórmula:C24H19N3O2Forma y color:SolidPeso molecular:381.43CHM-1-P-Na
CAS:CHM-1-P-Na is used as a hydrophilic prodrug of CHM-1.Fórmula:C16H11FNNaO6PForma y color:SolidPeso molecular:386.227Tubulin inhibitor 28
CAS:Compound 2g, a tubulin inhibitor with an IC50 of 1.2 μM, inhibits MCF-7 cell proliferation.Fórmula:C12H8Br2S2Forma y color:SolidPeso molecular:376.13Tubulin polymerization-IN-39
Tubulin-IN-39 inhibits polymerization (IC50: 4.9 μM), blocks colchicine site, stops cancer growth.Fórmula:C21H21N5O5Forma y color:SolidPeso molecular:423.42Anticancer agent 48
CAS:Compound 48: broad-spectrum, anti-proliferative, inhibits microtubules, active in vivo, with potential for tumor research.Fórmula:C26H25N3O4Forma y color:SolidPeso molecular:443.49Microtubule inhibitor 1
CAS:Microtubule inhibitor 1 is an antitumor agent with microtubule polymerization inhibitory activity(IC50 = 9-16 nM, in cancer cells).Fórmula:C21H19NO3Pureza:98%Forma y color:SolidPeso molecular:333.38Microtubule inhibitor 3
CAS:Compounds 17o and 17p with furan have IC50s of 14.0 and 2.9 nM, respectively, against NCI-H460 cancer cells.Fórmula:C26H23FN4O3Forma y color:SolidPeso molecular:458.48Amphethinile
CAS:Amphethinile is an anti-tubulin agent. The Ka of Amphethinile with tubulin is 1.3 μM.Fórmula:C15H11N3SPureza:98%Forma y color:SolidPeso molecular:265.33Sirt1/2-IN-1
CAS:Sirt1/2-IN-1 inhibits SIRT1 (IC50: 1.81 μg/mL) and SIRT2 (2.10 μg/mL), less on SIRT3 (20.5 μg/mL), with anticancer properties.Fórmula:C22H13ClN2OS2Forma y color:SolidPeso molecular:420.93Tubulozole
CAS:Tubulozole blocks mitosis by inhibiting microtubule dynamics, leading to cell cycle arrest and apoptosis.Fórmula:C23H23Cl2N3O4SPureza:98%Forma y color:SolidPeso molecular:508.42Mivobulin
CAS:Mivobulin is an inhibitor of tubulin .Fórmula:C17H19N5O2Pureza:98%Forma y color:SolidPeso molecular:325.37S-methyl DM1
CAS:S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds to tubulin(Kd of 0.93 μM) and inhibts microtubule polymerization.Fórmula:C36H50ClN3O10SPureza:98%Forma y color:SolidPeso molecular:752.31
