Asociado a microtúbulos
Los inhibidores de proteínas asociadas a microtúbulos se dirigen a proteínas que interactúan con los microtúbulos, los componentes estructurales del citoesqueleto de la célula, esenciales para la división celular. Estas proteínas regulan la estabilidad y la dinámica de los microtúbulos durante la mitosis. Inhibir las proteínas asociadas a microtúbulos puede interrumpir la función de los microtúbulos, lo que lleva al arresto del ciclo celular y la apoptosis, particularmente en células cancerosas de rápida división. Estos inhibidores se utilizan ampliamente en la investigación del cáncer y el desarrollo de fármacos. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteínas asociadas a microtúbulos de alta calidad para apoyar su investigación en división celular, dinámica del citoesqueleto y terapia contra el cáncer.
Se han encontrado 281 productos de "Asociado a microtúbulos"
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Alyssin, (S)-
CAS:Alyssin, (S)-, is an analogue of Sulforaphane that has been shown to have cytotoxic effect on CCRF-SB leukemia cells and lymphoblastoid cells.Fórmula:C7H13NOS2Forma y color:SolidPeso molecular:191.31OX01914
CAS:OX01914 is a soluble modulator to increase utrophin in DMD studies, EC50 20.5 μM.Fórmula:C17H14N4OForma y color:SolidPeso molecular:290.32Denibulin HCl
CAS:Denibulin (MN-029) disrupts tumor blood vessels by inhibiting microtubule assembly, enhancing radiation and cisplatin efficacy.Fórmula:C18H20ClN5O3SForma y color:SolidPeso molecular:421.9Centmitor-1
CAS:Centmitor-1 is a novel mitotic inducer that modulates the positive end of microtubules and reduces microtubule dynamics.Fórmula:C22H16BrN3O3Forma y color:SolidPeso molecular:450.28CAY10701
CAS:CAY10701, a 7-deazahypoxanthine, impedes cell growth (GI50: 9-38 nM) while sparing normal fibroblasts (>1,500-fold), and shrinks mouse colorectal tumors.Fórmula:C24H19N3O2Forma y color:SolidPeso molecular:381.43CHM-1-P-Na
CAS:CHM-1-P-Na is used as a hydrophilic prodrug of CHM-1.Fórmula:C16H11FNNaO6PForma y color:SolidPeso molecular:386.227Mivobulin
CAS:Mivobulin is an inhibitor of tubulin .Fórmula:C17H19N5O2Pureza:98%Forma y color:SolidPeso molecular:325.37S-methyl DM1
CAS:S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds to tubulin(Kd of 0.93 μM) and inhibts microtubule polymerization.Fórmula:C36H50ClN3O10SPureza:98%Forma y color:SolidPeso molecular:752.31Cevipabulin
CAS:Cevipabulin (TTI-237) is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cellFórmula:C18H18ClF5N6OPureza:99.53%Forma y color:SolidPeso molecular:464.82Tau-aggregation and neuroinflammation-IN-1
CAS:Potent tau aggregate inhibitor, anti-inflammatory, low cytotoxicity, reverses memory impairment in rats.Fórmula:C25H20N2O7Pureza:99.85%Forma y color:SolidPeso molecular:460.44CCB02
CAS:CCB02 is a selective CPAP-tubulin interaction inhibitor (IC50: 689 nM) with anti-tumor activity.Fórmula:C14H9N3OPureza:98.38%Forma y color:SolidPeso molecular:235.24Ref: TM-T10704
1mg73,00€5mg161,00€10mg245,00€25mg480,00€50mg735,00€100mg999,00€1mL*10mM (DMSO)172,00€S516
CAS:S516 is an active CKD-516 metabolite and is a potent inhibitor of tubulin polymerization(IC50 of 4.29 μM), has marked antitumor activity.Fórmula:C21H19N5O4SPureza:98%Forma y color:SolidPeso molecular:437.47Sabeluzole
CAS:Sabeluzole (R-58735) has antiepileptic and cognitive enhancing properties and may be used in the study of Alzheimer's disease.Fórmula:C22H26FN3O2SPureza:98.51%Forma y color:SolidPeso molecular:415.52LY3372689
CAS:LY3372689 (Formulaic Ia) is an orally active O-GlcNAcase (OGA) enzyme inhibitor for tau protein-based disorders including Alzheimer's disease.
Fórmula:C16H22FN5O3SPureza:99.43% - 99.53%Forma y color:SolidPeso molecular:383.44TCS 2210
CAS:TCS 2210 promotes neuronal differentiation in stem cells, boosting β-III tubulin and enolase markers.Fórmula:C18H17N3O3Pureza:98.62%Forma y color:SolidPeso molecular:323.35Ref: TM-T23446
1mg90,00€2mg123,00€5mg182,00€10mg274,00€25mg469,00€50mg643,00€100mg914,00€500mg1.833,00€1mL*10mM (DMSO)187,00€DM1-SMe
CAS:DM1-SMe (DM1-SSMe) potently inhibits microtubules, 3-10x stronger than Maytansine with IC50s of 0.003-0.01 nM in human cancer cells.
Fórmula:C36H50ClN3O10S2Pureza:99.61%Forma y color:SolidPeso molecular:784.38Tubulin inhibitor 8
CAS:Tubulin inhibitor 8 blocks tubulin polymerization, stunts K562 cancer cell growth; IC50: 0.73 μM, 14 nM.
Fórmula:C21H14N2O3Pureza:98.51% - 99.87%Forma y color:SolidPeso molecular:342.35Erbulozole
CAS:Erbulozole (R 55104) is a synthetic microtubule inhibitor with anti-invasive activity that induces Wernicke's encephalopathy-like neurotoxicity.Fórmula:C24H27N3O5SPureza:99.88%Forma y color:SolidPeso molecular:469.55Rosabulin
CAS:v Rosabulin (STA 5312) is an orally active microtubule inhibitor with potency.Fórmula:C22H16N4O2SPureza:98.86%Forma y color:SolidPeso molecular:400.45Ref: TM-T16788
1mg92,00€5mg230,00€10mg344,00€25mg623,00€50mg888,00€100mg1.341,00€1mL*10mM (DMSO)251,00€CID-663143
CAS:CID-663143 inhibits cancer cell growth and shows microtubule-binding activity.Fórmula:C19H18N4O2SPureza:99.68% - 99.77%Forma y color:SolidPeso molecular:366.44Ref: TM-T23889
1mg52,00€5mg111,00€10mg163,00€25mg235,00€50mg333,00€100mg447,00€200mg592,00€1mL*10mM (DMSO)115,00€
