Asociado a microtúbulos
Los inhibidores de proteínas asociadas a microtúbulos se dirigen a proteínas que interactúan con los microtúbulos, los componentes estructurales del citoesqueleto de la célula, esenciales para la división celular. Estas proteínas regulan la estabilidad y la dinámica de los microtúbulos durante la mitosis. Inhibir las proteínas asociadas a microtúbulos puede interrumpir la función de los microtúbulos, lo que lleva al arresto del ciclo celular y la apoptosis, particularmente en células cancerosas de rápida división. Estos inhibidores se utilizan ampliamente en la investigación del cáncer y el desarrollo de fármacos. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteínas asociadas a microtúbulos de alta calidad para apoyar su investigación en división celular, dinámica del citoesqueleto y terapia contra el cáncer.
Se han encontrado 284 productos de "Asociado a microtúbulos"
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Microtubule inhibitor 4
CAS:Microtubule inhibitor 4 (Compound 2) blocks polymerization, toxic to HT-29 cells (IC50: 2.1 nM).Fórmula:C25H23FN4O3Forma y color:SolidPeso molecular:446.47BNC105P
CAS:BNC105P, a prodrug VDA, converts to BNC105, blocks tubulin polymerization, disrupts tumor vessels, and evades P-glycoprotein resistance.Fórmula:C20H21O10PForma y color:SolidPeso molecular:452.3485Tubulin polymerization-IN-29
CAS:Tubulin polymerization-IN-29 inhibits microtubule assembly, has anti-proliferative properties, and arrests HeLa cells at G2/M.Fórmula:C25H20FNO6Forma y color:SolidPeso molecular:449.43isoCA-4
CAS:isoCA-4 is a Combretastatin A4 derivative. isoCA-4 is a tubulin polymerization inhibitor with anti-proliferative activities [1].Fórmula:C18H20O5Forma y color:SolidPeso molecular:316.35IDT
CAS:IDT, an oral TNFα modulator, changes neutrophil levels, boosts cognition, and reduces tau/amyloid in 3xTgAD mice.Fórmula:C8H5NS2Pureza:98%Forma y color:SolidPeso molecular:179.26DHNQ
CAS:DHNQ is a novel inhibitor of the PI3K enzyme activity and transcriptional as well as translational expression levels in colorectal cancer (CRC).Fórmula:C18H14N2OForma y color:SolidPeso molecular:274.32D011-2120
CAS:D011-2120: Antiviral that blocks microtubule growth, disrupts Golgi, and hinders viral egress.Fórmula:C17H15NO3Pureza:98%Forma y color:SolidPeso molecular:281.31DAT1
CAS:DAT1 is an antimitotic and antiangiogenic that acts by binding to the colchicine binding site of tubulin.Fórmula:C17H15N3O2SPureza:98%Forma y color:SolidPeso molecular:325.38Acodazole
CAS:Acodazole is a synthetic imidazoquinoline. It has antimicrobial and antineoplastic properties. It also has been shown to treat arrhythmias.Fórmula:C20H19N5OPureza:98%Forma y color:SolidPeso molecular:345.4Acodazole hydrochloride
CAS:Acodazole hydrochloride: synthetic imidazoquinoline with antineoplastic activity; disrupts DNA replication by intercalation.Fórmula:C20H20ClN5OPureza:98%Forma y color:SolidPeso molecular:381.86LDN-193665
CAS:LDN-193665 is a potent inhibitor of tau kinase. It acts by targeting CDK5/p25 and GSK3β.Fórmula:C15H11FN4OSPureza:98%Forma y color:SolidPeso molecular:314.34MG-2119
CAS:MG-2119 is a potent inhibitor of monomeric tau and α-syn aggregation and can be used to study neurological diseases.Fórmula:C27H29N5O4Forma y color:SolidPeso molecular:487.55Aha1/Hsp90-IN-1
CAS:Aha1/Hsp90-IN-1 (Compound 17) inhibits Aha1/Hsp90, preventing tau aggregation; IC50 = 3.32 μM.Fórmula:C22H17F3N4O2Forma y color:SolidPeso molecular:426.39Tubulin polymerization-IN-27
CAS:Compound 5j inhibits tubulin polymerization, arrests cell cycle at G2/M phase, and induces apoptosis.Fórmula:C22H20N2O2Forma y color:SolidPeso molecular:344.41GF 15
CAS:GF 15 is a potent inhibitor of centrosomal clustering in tumor cells.Fórmula:C23H21ClO6Pureza:98%Forma y color:SolidPeso molecular:428.86OSIP-486823
CAS:OSIP-486823（CP248） is a novel and potent microtubule disruptor with affinity for both protein kinase G (PKG) and microtubules.Fórmula:C29H28FNO4Pureza:98.59%Forma y color:SolidPeso molecular:473.54DJ101
CAS:DJ101: A stable tubulin inhibitor that bypasses multidrug resistance efflux pumps.Fórmula:C23H20N4O3Pureza:98%Forma y color:SolidPeso molecular:400.43Tubulin polymerization-IN-19
CAS:Tubulin aggregation-IN-19 (compound 4) is a potent tubulin aggregation inhibitor that has shown potential in breast cancer and drug-resistant colon cancer.Fórmula:C25H25NO5Forma y color:SolidPeso molecular:419.47Anticancer agent 49
CAS:Anticancer agent 49, also 69, hinders cell growth and microtubule aggregation, with potential in solid and blood cancer research.Fórmula:C26H25N3O4Forma y color:SolidPeso molecular:443.49TOK-8801
CAS:TOK-8801 is a dihydroimidazole thiazole carboxamide with immunomodulatory activity.Fórmula:C17H21N3OSPureza:99.97%Forma y color:SolidPeso molecular:315.43
