Dynamin
Los inhibidores de dinamina se dirigen a la dinamina, una enzima GTPasa que desempeña un papel crucial en la endocitosis, el tráfico vesicular y la citocinesis. La dinamina está involucrada en la escisión de vesículas a partir de las membranas y es esencial para la correcta distribución de los componentes celulares durante la división celular. Inhibir la dinamina puede interrumpir estos procesos, lo que lleva a defectos en la división celular e induce el arresto del ciclo celular. Los inhibidores de dinamina son valiosos para estudiar la endocitosis, la división celular y la dinámica de las membranas. En CymitQuimica, ofrecemos una gama de inhibidores de dinamina de alta calidad para apoyar su investigación en biología celular, tráfico de membranas y regulación del ciclo celular.
Se han encontrado 23 productos de "Dynamin"
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DynaMin inhibitory peptide, myristoylated
CAS:<p>Cell-permeable dynamin inhibitor; blocks its binding to amphiphysin, hindering endocytosis; curbs NMDA receptor internalization.</p>Fórmula:C61H107N19O14Pureza:98%Forma y color:SolidPeso molecular:1330.64TAT-P110
CAS:<p>TAT-P110 is a peptide inhibitor that disrupts the interaction between Drp1 and Fis1, effectively reducing pathological changes in various models of neurodegenerative diseases, ischemia, and sepsis without impairing the physiological function of Drp1.</p>Fórmula:C100H178N44O26Peso molecular:2412.76Dynamin inhibitory peptide TFA
<p>Dynamin inhibitory peptide TFA hinders dynamin-amphiphysin interaction and endocytosis, affecting dopamine D3 and GABA A receptors.</p>Fórmula:C49H81F3N18O16Forma y color:SolidPeso molecular:1235.27Drp1 peptide inhibitor P110
CAS:<p>Compound P110 (Drp1 peptide inhibitor P110) is a selective Drp1 peptide inhibitor with neuroprotective effects. It inhibits the activation of Drp1, prevents Drp1 mitochondrial translocation induced by MPTP, and alleviates dopamine neuron loss, dopaminergic terminal damage, and behavioral deficits caused by MPTP. This compound is useful for Alzheimer's disease research. Additionally, Compound P110 reduces mitochondrial and organ damage in animal models of Huntington's disease, cerebral ischemia, and myocardial infarction.</p>Fórmula:C100H179N45O25Forma y color:SolidPeso molecular:2411.78IIQLPEIVVV TFA
<p>IIQLPEIVVV TFA serves as a specific inhibitor targeting the Drp1-Mff interaction. This compound discriminates between physiological and pathological fission, hindering physiological fission which leads to mitochondrial dysfunction. IIQLPEIVVV TFA is also utilized in research related to Huntington's disease.</p>Fórmula:C54H95N11O14·xC2HF3O2Forma y color:SolidPeso molecular:1122.40 (free base)Dynamin IN-2
CAS:<p>Dynamin IN-2 (compound 43) is a Wiskostatin analogue.</p>Fórmula:C22H21ClN2OPureza:99.36% - 99.37%Forma y color:SoildPeso molecular:364.87Anti-Clathrin Heavy Chain Antibody
<p>Anti-Clathrin Heavy Chain Antibody is a human-source antibody expressed in CHO cells, specifically targeting the Clathrin Heavy Chain. For isotype control, please refer to Human IgG1 kappa, Isotype Control.</p>Forma y color:Odour LiquidSchaftoside
CAS:<p>Schaftoside (APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE) has antioxidant and anticancer activity.</p>Fórmula:C26H28O14Pureza:98% - >99.99%Forma y color:SolidPeso molecular:564.49Mdivi-1
CAS:<p>Mdivi-1 (Mitochondrial division inhibitor 1) is a mitochondrial division inhibitor that inhibits DRP1 and Dynamin I (IC50=1-10 μM).</p>Fórmula:C15H10Cl2N2O2SPureza:96.57% - 99.23%Forma y color:SolidPeso molecular:353.22Dynasore
CAS:<p>Dynasore, a cell-permeable dynamin inhibitor, blocks GTPase of dynamin 1/2 and Drp1 (IC50: 15 μM) without affecting other small GTPases.</p>Fórmula:C18H14N2O4Pureza:95.85% - 99.22%Forma y color:SolidPeso molecular:322.31Tetradecyltrimethylammonium bromide
CAS:<p>Tetradecyltrimethylammonium bromide (MitMAB) is a Dynamin GTPase activity inhibitor and a cationic surfactant with asymmetrical structure.</p>Fórmula:C17H38BrNPureza:99.80%Forma y color:SolidPeso molecular:336.39Trimethyloctadecylammonium bromide
CAS:<p>Trimethyloctadecylammonium bromide is an inhibitor of Dynamin I(IC50 : 1.9 μM) and also inhibits Dynamin Ⅱ.</p>Fórmula:C21H46N·BrPureza:99.09%Forma y color:Solid SolidPeso molecular:392.5Hydroxy-Dynasore
CAS:<p>Hydroxy-Dynasore (Dyngo-4a) , a effective dynamin inhibitor, inhibits withDynI (brain), DynI (rec), and DynII (rec) of IC50 of 0.38 μM, 1.1 μM, and 2.3 μM,</p>Fórmula:C18H14N2O5Pureza:97.60% - >99.99%Forma y color:SolidPeso molecular:338.31DNM1 Protein, Human, Recombinant (His)
<p>Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP.</p>Forma y color:Lyophilized PowderPeso molecular:32.2 kDa (predicted)Clathrin-IN-25
CAS:<p>Clathrin-IN-25 is the most effective clathrin terminal domain-amphiphysin inhibitor reported to date.</p>Fórmula:C19H13KNO5SForma y color:SolidPeso molecular:406.47Dynamin IN-1
CAS:<p>Dynamin IN-1 is a potent dynamin inhibitor with an IC 50 value of 1.0 µM .</p>Fórmula:C23H24N2OForma y color:SolidPeso molecular:344.45DRP1i27
CAS:<p>DRP1i27 inhibits human Drp1 at GTPase site, prevents mitochondrial fission, and shields cells from ischemia-reperfusion damage.</p>Fórmula:C20H26N6OForma y color:SolidPeso molecular:366.46Clathrin-IN-2
CAS:<p>Clathrin-IN-2: CME inhibitor, IC50 - 2.3μM; also blocks dyn I GTPase, IC50 - 7.7μM.</p>Fórmula:C17H18Br2N2OForma y color:SolidPeso molecular:426.15Ellipticine quinone
CAS:<p>Ellipticine quinone (NSC-383230) outperforms mdivi-1 in inhibiting Drp1, reduces lung cancer growth, and lessens IR injury by curbing mitochondrial issues.</p>Fórmula:C15H8N2O2Forma y color:SolidPeso molecular:248.24Drp1-IN-1
CAS:<p>Drp1-IN-1 (comp A-7) is a Drp1 protein inhibitor (IC50: 0.91 μM).</p>Fórmula:C22H24N8OSForma y color:SolidPeso molecular:448.54
