Dynamin
Los inhibidores de dinamina se dirigen a la dinamina, una enzima GTPasa que desempeña un papel crucial en la endocitosis, el tráfico vesicular y la citocinesis. La dinamina está involucrada en la escisión de vesículas a partir de las membranas y es esencial para la correcta distribución de los componentes celulares durante la división celular. Inhibir la dinamina puede interrumpir estos procesos, lo que lleva a defectos en la división celular e induce el arresto del ciclo celular. Los inhibidores de dinamina son valiosos para estudiar la endocitosis, la división celular y la dinámica de las membranas. En CymitQuimica, ofrecemos una gama de inhibidores de dinamina de alta calidad para apoyar su investigación en biología celular, tráfico de membranas y regulación del ciclo celular.
Se han encontrado 27 productos de "Dynamin"
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Anti-Clathrin Heavy Chain Antibody
Anti-Clathrin Heavy Chain Antibody is a human-source antibody expressed in CHO cells, specifically targeting the Clathrin Heavy Chain. For isotype control, please refer to Human IgG1 kappa, Isotype Control.Forma y color:Odour LiquidTAT-P110
CAS:TAT-P110 is a peptide inhibitor that disrupts the interaction between Drp1 and Fis1, effectively reducing pathological changes in various models of neurodegenerative diseases, ischemia, and sepsis without impairing the physiological function of Drp1.Fórmula:C100H178N44O26Peso molecular:2412.76Dynamin inhibitory peptide TFA
Dynamin inhibitory peptide TFA hinders dynamin-amphiphysin interaction and endocytosis, affecting dopamine D3 and GABA A receptors.Fórmula:C49H81F3N18O16Forma y color:SolidPeso molecular:1235.27Drp1 peptide inhibitor P110
CAS:Compound P110 (Drp1 peptide inhibitor P110) is a selective Drp1 peptide inhibitor with neuroprotective effects. It inhibits the activation of Drp1, prevents Drp1 mitochondrial translocation induced by MPTP, and alleviates dopamine neuron loss, dopaminergic terminal damage, and behavioral deficits caused by MPTP. This compound is useful for Alzheimer's disease research. Additionally, Compound P110 reduces mitochondrial and organ damage in animal models of Huntington's disease, cerebral ischemia, and myocardial infarction.Fórmula:C100H179N45O25Forma y color:SolidPeso molecular:2411.78IIQLPEIVVV TFA
IIQLPEIVVV TFA serves as a specific inhibitor targeting the Drp1-Mff interaction. This compound discriminates between physiological and pathological fission, hindering physiological fission which leads to mitochondrial dysfunction. IIQLPEIVVV TFA is also utilized in research related to Huntington's disease.Fórmula:C54H95N11O14·xC2HF3O2Forma y color:SolidPeso molecular:1122.40 (free base)ES9-17
CAS:ES9-17, an ES9 analog, blocks clathrin-mediated endocytosis and impairs Arabidopsis root growth, affecting FM4-64 and transferrin uptake.Fórmula:C10H8BrNO2S2Pureza:99.93%Forma y color:SolidPeso molecular:318.21Ref: TM-T64368
5mg55,00€10mg82,00€25mg126,00€50mg182,00€100mg273,00€200mg409,00€1mL*10mM (DMSO)58,00€Dynamin IN-2
CAS:Dynamin IN-2 (compound 43) is a Wiskostatin analogue.Fórmula:C22H21ClN2OPureza:99.36% - 99.37%Forma y color:SoildPeso molecular:364.87Ref: TM-T64369
1mg133,00€5mg314,00€10mg416,00€25mg632,00€50mg847,00€100mg1.134,00€200mg1.513,00€1mL*10mM (DMSO)324,00€DynaMin inhibitory peptide, myristoylated
CAS:Cell-permeable dynamin inhibitor; blocks its binding to amphiphysin, hindering endocytosis; curbs NMDA receptor internalization.Fórmula:C61H107N19O14Pureza:98%Forma y color:SolidPeso molecular:1330.64Schaftoside
CAS:Schaftoside (APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE) has antioxidant and anticancer activity.Fórmula:C26H28O14Pureza:98% - >99.99%Forma y color:SolidPeso molecular:564.49Ref: TM-T3898
1mg39,00€5mg80,00€10mg105,00€25mg200,00€50mg295,00€100mg442,00€200mg620,00€1mL*10mM (DMSO)89,00€Mdivi-1
CAS:Mdivi-1 (Mitochondrial division inhibitor 1) is a mitochondrial division inhibitor that inhibits DRP1 and Dynamin I (IC50=1-10 μM).Fórmula:C15H10Cl2N2O2SPureza:96.57% - 99.23%Forma y color:SolidPeso molecular:353.22Ref: TM-T1907
5mg47,00€10mg56,00€25mg90,00€50mg153,00€100mg227,00€200mg338,00€500mg558,00€1mL*10mM (DMSO)50,00€Dynasore
CAS:Dynasore, a cell-permeable dynamin inhibitor, blocks GTPase of dynamin 1/2 and Drp1 (IC50: 15 μM) without affecting other small GTPases.Fórmula:C18H14N2O4Pureza:95.85% - 99.22%Forma y color:SolidPeso molecular:322.31Ref: TM-T1848
5mg49,00€10mg79,00€25mg140,00€50mg259,00€100mg374,00€200mg560,00€500mg883,00€1mL*10mM (DMSO)87,00€Tetradecyltrimethylammonium bromide
CAS:Tetradecyltrimethylammonium bromide (MitMAB) is a Dynamin GTPase activity inhibitor and a cationic surfactant with asymmetrical structure.Fórmula:C17H38BrNPureza:99.80%Forma y color:SolidPeso molecular:336.39Trimethyloctadecylammonium bromide
CAS:<p>Trimethyloctadecylammonium bromide is an inhibitor of Dynamin I(IC50 : 1.9 μM) and also inhibits Dynamin Ⅱ.</p>Fórmula:C21H46N·BrPureza:99.09%Forma y color:Solid SolidPeso molecular:392.5Dynamin inhibitory peptide, myristoylated acetate
Myristoylated acetate peptide inhibits DynaMin, blocking amphiphysin binding; myristoylated TFA variant hinders endocytosis.Fórmula:C63H111N19O16Pureza:99.42%Forma y color:SolidPeso molecular:1390.67Hydroxy-Dynasore
CAS:Hydroxy-Dynasore (Dyngo-4a) , a effective dynamin inhibitor, inhibits withDynI (brain), DynI (rec), and DynII (rec) of IC50 of 0.38 μM, 1.1 μM, and 2.3 μM,Fórmula:C18H14N2O5Pureza:97.60% - >99.99%Forma y color:SolidPeso molecular:338.31Ref: TM-T6822
5mg50,00€10mg84,00€25mg137,00€50mg221,00€100mg329,00€200mg490,00€500mg783,00€1mL*10mM (DMSO)55,00€DNM1 Protein, Human, Recombinant (His)
Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP.Forma y color:Lyophilized PowderPeso molecular:32.2 kDa (predicted)Ref: TM-TMPH-01254
1mg1.648,00€5µg78,00€10µg111,00€20µg178,00€50µg268,00€100µg384,00€200µg592,00€500µg1.054,00€Dynamin IN-1
CAS:Dynamin IN-1 is a potent dynamin inhibitor with an IC 50 value of 1.0 µM .Fórmula:C23H24N2OForma y color:SolidPeso molecular:344.45MB 0223
CAS:DRP1 partial inhibitor (IC50 = 1.2 μM), selective over OPA1/DYN1, boosts mtDNA in mfn1-knockout MEFs.Fórmula:C26H27N5OSForma y color:SolidPeso molecular:457.59Ellipticine quinone
CAS:Ellipticine quinone (NSC-383230) outperforms mdivi-1 in inhibiting Drp1, reduces lung cancer growth, and lessens IR injury by curbing mitochondrial issues.Fórmula:C15H8N2O2Forma y color:SolidPeso molecular:248.24Drp1-IN-1
CAS:Drp1-IN-1 (comp A-7) is a Drp1 protein inhibitor (IC50: 0.91 μM).Fórmula:C22H24N8OSForma y color:SolidPeso molecular:448.54
