Cromatina / Epigenética
Los inhibidores de cromatina/epigenética son compuestos que modulan la estructura y función de la cromatina o interfieren con modificaciones epigenéticas, como la metilación del ADN y la modificación de histonas. Estos inhibidores son herramientas esenciales para estudiar la regulación de la expresión génica y el papel de la epigenética en enfermedades como el cáncer, los trastornos neurológicos y las anomalías del desarrollo. Al dirigirse a los procesos epigenéticos, estos inhibidores pueden alterar los patrones de expresión génica y ofrecer nuevas vías terapéuticas. En CymitQuimica, ofrecemos una amplia selección de inhibidores de cromatina/epigenética de alta calidad para apoyar su investigación en biología molecular, genética y epigenética.
Subcategorías de "Cromatina / Epigenética"
Se han encontrado 2235 productos de "Cromatina / Epigenética"
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TP-3654
CAS:<p>TP-3654 is a second-generation Pim kinase inhibitor (Ki values against Pim-1/3: 5/42 nM).</p>Fórmula:C22H25F3N4OPureza:99.8% - 99.95%Forma y color:SolidPeso molecular:418.46E7449
CAS:<p>E7449 is a potent inhibitor of PARP1, PARP2, TNKS1, and TNKS2 with IC50s of 2, 1, ~50, and ~50 nM respectively.</p>Fórmula:C18H15N5OPureza:97.13%Forma y color:SolidPeso molecular:317.34Protosappanin A
CAS:<p>Protosappanin A combats brain inflammation, suppresses rat heart transplant rejection, fights MRSA, and inhibits HIV with a 12.6 uM IC50.</p>Fórmula:C15H12O5Pureza:99.42% - 99.82%Forma y color:SolidPeso molecular:272.25Molibresib
CAS:<p>Molibresib (GSK525762) is an inhibitor of BET proteins (IC50: about 35 nM).</p>Fórmula:C22H22ClN5O2Pureza:97.70% - 99.08%Forma y color:SolidPeso molecular:423.9(+)-JQ1 PA
CAS:<p>(+)-JQ1 PA is a derivative of the Bromodomain and extra-terminal (BET) inhibitor JQ1(IC50 of 10.4 nM).</p>Fórmula:C22H20ClN5OSPureza:98.36%Forma y color:SolidPeso molecular:437.95WM-1119
CAS:<p>WM-1119 is a highly potent, selective KAT6A/B inhibitor</p>Fórmula:C18H13F2N3O3SPureza:96.59% - 99.58%Forma y color:SolidPeso molecular:389.38XD14
CAS:<p>XD14 inhibits BET bromodomains with Kd: BRD4(1) 160nM, BRD2(1) 170nM, BRD3(1) 380nM, BRD3(2) 490nM, BRD2(2) 830nM, BRD4(2) 850nM.</p>Fórmula:C20H27N3O5SPureza:97.46%Forma y color:SolidPeso molecular:421.51FL-411
CAS:<p>FL-411 (BRD4-IN-1) is a potent and selective BRD4 inhibitor with an IC50 of 0.43±0.09 μM for BRD4.</p>Fórmula:C18H19N3O2SPureza:98.19%Forma y color:SolidPeso molecular:341.43GSK3685032
CAS:<p>GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM).</p>Fórmula:C22H24N6OSPureza:98.56% - 99.49%Forma y color:SolidPeso molecular:420.53Daminozide
CAS:<p>Daminozide (Succinic Acid) is a plant growth regulator, selectively inhibits the KDM2/7 JmjC subfamily.</p>Fórmula:C6H12N2O3Pureza:99.86%Forma y color:White Crystalline Solid Physical Description Odorless White Crystals Or Powder (Ntp 1992)Peso molecular:160.17GSK-5959
CAS:<p>GSK-5959 is a selective BRPF1 inhibitor with IC50 ~80 nM, 100-fold more specific than 35 other bromodomains.</p>Fórmula:C22H26N4O3Pureza:98.35% - 98.65%Forma y color:SolidPeso molecular:394.47Deucravacitinib
CAS:<p>Deucravacitinib (BMS-986165) is a highly selective, orally bioavailable, allosteric TYK2 inhibitor.Cost-effective and quality-assured.</p>Fórmula:C20H19D3N8O3Pureza:98.52% - >99.99%Forma y color:SolidPeso molecular:425.46Momelotinib
CAS:<p>Momelotinib (LM-1149), an oral JAK1/2 inhibitor with IC50s 11/18 nM, blocks ATP binding, disrupting JAK-STAT pathway and reducing tumor growth.</p>Fórmula:C23H22N6O2Pureza:97.47% - 99.56%Forma y color:SolidPeso molecular:414.46MS436
CAS:<p>MS436 is a selective, small-molecule inhibitor for the BRD4 bromodomains.</p>Fórmula:C18H17N5O3SPureza:97.95% - 98.92%Forma y color:SolidPeso molecular:383.42SNS-314 Mesylate
CAS:<p>SNS-314 Mesylate (SNS-314) is an effective and specific Aurora A/B/C inhibitor. SNS-314 is less inhibition of Trk A/B, Fms, Flt4, c-Raf, Axl, and DDR2.</p>Fórmula:C18H15ClN6OS2·CH4O3SPureza:99.44% - 99.92%Forma y color:SolidPeso molecular:527.04BAY-598
CAS:<p>BAY 598 is a potent and selective competitive inhibitor of SMYD2, exhibiting >100-fold selectivity over SMYD3, SUV420H1, and SUV420H2. Cost-effective and quality-assured.</p>Fórmula:C22H20Cl2F2N6O3Pureza:99.18% - 99.78%Forma y color:SolidPeso molecular:525.342',3',5'-triacetyl-5-Azacytidine
CAS:<p>2',3',5'-triacetyl-5-Azacytidine (Nsc291930) is a prodrug form of 5-azacytidine that may be rapidly absorbed orally.</p>Fórmula:C14H18N4O8Pureza:98.34%Forma y color:SolidPeso molecular:370.31GSK046
CAS:<p>GSK046 (iBET-BD2), potent oral BET BD2 inhibitor; IC50: BRD2 (264 nM), BRD3 (98 nM), BRD4 (49 nM), BRDT (214 nM); immunomodulatory.</p>Fórmula:C23H27FN2O4Pureza:99.97%Forma y color:SolidPeso molecular:414.47RO495
CAS:<p>RO495 (CS-2667), a potent inhibitor of TYK2, inhibits TYK2 with IC50 of 1.5nM as tested in cell-based pharmacological assays</p>Fórmula:C17H14Cl2N6OPureza:97.94%Forma y color:SolidPeso molecular:389.24GSK6853
CAS:<p>GSK6853 is a potent, soluble, cell-active, and highly selective inhibitor of the BRPF1 bromodomain.</p>Fórmula:C22H27N5O3Pureza:98.71% - 99.21%Forma y color:SolidPeso molecular:409.48(Z)-LFM-A13
CAS:<p>(Z)-LFM-A13(IC50=2.5 μM), a specific Bruton's tyrosine kinase (BTK), is more than 100-fold specificity than other protein kinases, such as JAK1, JAK2, HCK, EGFR, and IRK.</p>Fórmula:C11H8Br2N2O2Pureza:99.88%Forma y color:SolidPeso molecular:360Niraparib
CAS:<p>Niraparib (MK-4827) inhibits PARP1/PARP2 (IC50: 3.8/2.1 nM), effective on BRCA mutant cancers, 330x less effective on PARP3, V-PARP, Tank1.</p>Fórmula:C19H20N4OPureza:98% - 99.91%Forma y color:SolidPeso molecular:320.39AKBA
CAS:<p>AKBA (3-O-Acetyl-11-keto-beta-boswellic acid), a natural component from frankincense, is a novel activator of Nrf2.</p>Fórmula:C32H48O5Pureza:97.85% - 99.77%Forma y color:SolidPeso molecular:512.72MN-64
CAS:<p>MN-64 is a tankyrases inhibitor, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition.</p>Fórmula:C18H16O2Pureza:99.5% - 99.93%Forma y color:SolidPeso molecular:264.32SGC0946
CAS:<p>SGC0946 is a highly effective and specific DOT1L methyltransferase inhibitor (IC50: 0.3 nM); selectively kill mixed lineage leukemia cells.</p>Fórmula:C28H40BrN7O4Pureza:98% - 99.82%Forma y color:SolidPeso molecular:618.57SMI-16a
CAS:<p>SMI-16a (PIM1/2 Kinase Inhibitor VI) , a cell-permeable thiazolidinedione compound, acts as an effective, ATP-competitive inhibitor against Pim-1/2 kinases (</p>Fórmula:C13H13NO3SPureza:99.99%Forma y color:SolidPeso molecular:263.31OF-1
CAS:<p>OF-1 is a potent inhibitor of BRPF1B and BRPF2 bromodomain.</p>Fórmula:C17H18BrN3O4SPureza:98.55% - ≥95%Forma y color:SolidPeso molecular:440.31AT9283
CAS:<p>AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).</p>Fórmula:C19H23N7O2Pureza:99.83% - 99.98%Forma y color:SolidPeso molecular:381.43SETDB1-TTD-IN-1
CAS:<p>SETDB1-TTD-IN-1 is a potent and selective inhibitor of SET domain bifurcated protein 1 tandem tudor domain (SETDB1-TTD, Kd = 88 nM).Cost-effective and quality-assured.</p>Fórmula:C28H31N5O2Pureza:98.26% - 99.96%Forma y color:SolidPeso molecular:469.58JMJD7-IN-1
CAS:<p>JMJD7-IN-1 (Benzoic acid, 2,4-dichloro-, 5-nitro-8-quinolinyl ester) is a potent JMJD7 inhibitor, with an IC50 of 6.62 μM.</p>Fórmula:C16H8Cl2N2O4Pureza:99.66%Forma y color:SolidPeso molecular:363.15PF-9366
CAS:<p>PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor (IC50: 420 nM; Kd: 170 nM).</p>Fórmula:C20H19ClN4Pureza:97.28% - 99.88%Forma y color:SolidPeso molecular:350.84AG-270
CAS:<p>AG-270 is an allosteric and orally active inhibitor of MAT2A.</p>Fórmula:C30H27N5O2Pureza:98.28% - 98.87%Forma y color:SolidPeso molecular:489.57C-82
CAS:<p>C-82 is a specific CBP/β-catenin antagonist. It inhibits the binding between β-catenin and CBP and increases the binding between β-catenin and p300.</p>Fórmula:C33H34N6O4Pureza:98.86% - 99.66%Forma y color:SolidPeso molecular:578.66Itacitinib
CAS:<p>Itacitinib (INCB039110) is an orally bioavailable inhibitor of Janus-associated kinase 1 (JAK1) with potential antineoplastic activity.</p>Fórmula:C26H23F4N9OPureza:96.4% - 99.5%Forma y color:SolidPeso molecular:553.51A-966492
CAS:<p>A-96649 is a new-type and effective inhibitor. The Ki of A-966492 for PARP1 and PARP2 is 1 nM and 1.5 nM, respectively.</p>Fórmula:C18H17FN4OPureza:98.53% - 99.27%Forma y color:SolidPeso molecular:324.35GSK503
CAS:<p>GSK-503, a potent EZH2 inhibitor, has potential antitumor activity.</p>Fórmula:C31H38N6O2Pureza:98% - 99.89%Forma y color:SolidPeso molecular:526.67PFI-4
CAS:<p>PFI-4 is a potent and selective and cell-permeable BRPF1 bromodomain inhibitor.</p>Fórmula:C21H24N4O3Pureza:99.53% - ≥95%Forma y color:SolidPeso molecular:380.44NI-57
CAS:<p>NI-57 inhibits BRPF family proteins: BRPF1 (IC50=3.1nM), BRPF2 (IC50=46nM), BRPF3 (IC50=140nM).</p>Fórmula:C19H17N3O4SPureza:99.88% - >99.99%Forma y color:SolidPeso molecular:383.42Menin-MLL inhibitor MI-2
CAS:<p>Menin-MLL inhibitor MI-2 (MI2) is a potent menin-MLL interaction inhibitor with IC50 of 446 nM.</p>Fórmula:C18H25N5S2Pureza:97.46%Forma y color:SolidPeso molecular:375.55Molibresib besylate
CAS:<p>Molibresib besylate (GSK 525762C) is a BET protein family inhibitor used in the study of refractory hematologic malignant diseases.</p>Fórmula:C28H28ClN5O5SPureza:99.64% - 99.64%Forma y color:SolidPeso molecular:582.07Oroxylin A
CAS:<p>Oroxylin A fights tumors, aids RAS therapy, promotes CaCo-2 cell apoptosis, blocks MCF-7 cell invasion and enhances leukemia treatment.</p>Fórmula:C16H12O5Pureza:98.72% - 99.55%Forma y color:SolidPeso molecular:284.26Tofacitinib
CAS:<p>Tofacitinib (Tasocitinib) is an orally Janus kinase inhibitor. Tofacitinib is used for the treatment of rheumatoid arthritis. Cost effective and quality assured.</p>Fórmula:C16H20N6OPureza:99% - >99.99%Forma y color:SolidPeso molecular:312.37GSK126
CAS:<p>GSK126 (GSK2816126A) is a excellently specific EZH2 methyltransferase inhibitor ( IC50=9.9 nM).</p>Fórmula:C31H38N6O2Pureza:98% - 99.67%Forma y color:SolidPeso molecular:526.67Seclidemstat
CAS:<p>Seclidemstat (SP-2577) is an effective LSD1 inhibitor, with a mean IC50 of 127 nM.</p>Fórmula:C20H23ClN4O4SPureza:98.28% - 99.76%Forma y color:SolidPeso molecular:450.94Veliparib dihydrochloride
CAS:<p>Veliparib dihydrochloride (ABT-888 dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively.</p>Fórmula:C13H18Cl2N4OPureza:98% - 99.81%Forma y color:SolidPeso molecular:317.21Remodelin
CAS:<p>Remodelin is an effective and specific inhibitor of the acetyl-transferase protein NAT10.</p>Fórmula:C15H14N4SPureza:99.39% - 99.83%Forma y color:SolidPeso molecular:282.363PT-2385
CAS:<p>PT-2385 is a selective HIF-2α inhibitor (Kd<50 nM).</p>Fórmula:C17H12F3NO4SPureza:98.91% - 99.55%Forma y color:SolidPeso molecular:383.34Venadaparib
CAS:<p>Venadaparib, a PARP inhibitor (IC50: 1.4/1.0 nM for PARP1/2), is orally active, selective, not affecting PARP-5, used in tumor studies.</p>Fórmula:C23H23FN4O2Pureza:99.86%Forma y color:SolidPeso molecular:406.45RN-1 dihydrochloride
CAS:<p>RN-1 dihydrochloride is an effective and selective irreversible inhibitor of lysine-specific demethylase 1 (LSD1, IC50 = 70 nM).</p>Fórmula:C23H31Cl2N3O2Pureza:99.64%Forma y color:SolidPeso molecular:452.42Ruxolitinib
CAS:<p>Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective.</p>Fórmula:C17H18N6Pureza:99.4% - >99.99%Forma y color:SolidPeso molecular:306.36GSK2801
CAS:<p>GSK2801 is an effective, specific and cell active acetyl-lysine competitive inhibitor of BAZ2A(Kd: 136 nM) and BAZ2B(Kd: 257 nM) bromodomains.</p>Fórmula:C20H21NO4SPureza:97.78% - 99.45%Forma y color:SolidPeso molecular:371.455-Methyl-2'-deoxycytidine
CAS:<p>5-Methyl-2'-deoxycytidine (5MedCyd) is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo.</p>Fórmula:C10H15N3O4Pureza:99.18% - 99.69%Forma y color:SolidPeso molecular:241.242-methyl-2,3,4,5-tetrahydro-1,5-benzothiazepin-4-one
CAS:<p>2-methyl-2,3-dihydro-1,5-benzothiazepin-4(5H)-one is ligand of CBP.</p>Fórmula:C10H11NOSPureza:99.68%Forma y color:SolidPeso molecular:193.275-Fluoro-2'-deoxycytidine
CAS:<p>5-Fluoro-2'-deoxycytidine (2'-DEOXY-5-FLUOROCYTIDINE) is an inhibitor of DNA methyltransferase (DNMT) .</p>Fórmula:C9H12FN3O4Pureza:97.91%Forma y color:Fine White PowderPeso molecular:245.21A-366
CAS:<p>A-366 is a highly selective peptide-competitive histone methyltransferase G9a inhibitor with IC50s of 3.3 and 38 nM for G9a and GLP, respectively.</p>Fórmula:C19H27N3O2Pureza:97.28% - 99.8%Forma y color:SolidPeso molecular:329.44UNC3866 TFA(1872382-47-2 free base)
CAS:<p>UNC3866 TFA is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen.</p>Fórmula:C45H67F3N6O10Pureza:98.43%Forma y color:SolidPeso molecular:909.046-Thioguanine
CAS:<p>6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.</p>Fórmula:C5H5N5SPureza:98.34% - >99.99%Forma y color:Odorless Or Almost Odorless Pale Yellow Crystalline PowderPeso molecular:167.19IOX4
CAS:<p>IOX4 is a potent PHD2 inhibitor (IC50 = 1.6 nM)</p>Fórmula:C15H16N6O3Pureza:99.97%Forma y color:SolidPeso molecular:328.33NEO2734
CAS:<p>NEO2734 (EP31670) is an orally active and selective inhibitor of p300/CBP and BET bromodomain(IC50 of <30 nM for both p300/CBP and BET bromodomains).</p>Fórmula:C22H24F3N3O3Pureza:98.72% - 98.8%Forma y color:SolidPeso molecular:435.44GSK343
CAS:<p>GSK343, a specific and effective EZH2 inhibitor (IC50=4 nM), exhibits 60 fold specificity activity against EZH1, and >1000 fold specificity activity against</p>Fórmula:C31H39N7O2Pureza:98% - 99.9%Forma y color:SolidPeso molecular:541.69Panaxadiol
CAS:<p>Panaxadiol (20(R)-Panaxadiol) is a novel antitumor agent extracted from the Chinese medical herb Panax ginseng.</p>Fórmula:C30H52O3Pureza:98% - 99.9%Forma y color:SolidPeso molecular:460.73XL228
CAS:<p>XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).</p>Fórmula:C22H31N9OPureza:99.07%Forma y color:SolidPeso molecular:437.54Tozasertib
CAS:<p>Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C).</p>Fórmula:C23H28N8OSPureza:99.99%Forma y color:SolidPeso molecular:464.591-benzyl-2-ethyl-4,5,6,7-tetrahydro-1H-indol-4-one
CAS:<p>1-benzyl-2-ethyl-4,5,6,7-tetrahydro-1H-indol-4-one is an inhibitor Bromodomain-containing protein 4 (human).</p>Fórmula:C17H19NOPureza:99.08%Forma y color:SolidPeso molecular:253.34GSK620
CAS:<p>GSK620, a selective pan-BD2 inhibitor, has anti-inflammatory properties and favorable oral pharmacokinetics.</p>Fórmula:C18H19N3O3Pureza:99.42% - 99.88%Forma y color:SolidPeso molecular:325.36Talazoparib
CAS:<p>Talazoparib (LT-673) is a new-type PARP inhibitor (IC50: 0.58 nM), It similarly binds to PARP1/2 (Kis: 1.2/0.85 nM).</p>Fórmula:C19H14F2N6OPureza:97.02% - 99.92%Forma y color:SolidPeso molecular:380.35Solcitinib
CAS:<p>Solcitinib (GLPG-0778), a JAK1 inhibitor, may treat psoriasis, ulcerative colitis, and lupus.</p>Fórmula:C22H23N5O2Pureza:99.61% - 99.82%Forma y color:SolidPeso molecular:389.45Dbet57
CAS:<p>dBET57: PROTAC-based BRD4BD1 degrader, DC50/5h at 500 nM, ineffective on BRD4BD2.</p>Fórmula:C34H31ClN8O5SPureza:99.36% - 99.52%Forma y color:SolidPeso molecular:699.18MAT2A inhibitor 4
CAS:<p>MAT2A Inhibitor 4 acts as an inhibitor targeting the catalytic subunit of methionine S-adenosyltransferase-2 (MAT2A), offering potential utility in cancer</p>Fórmula:C16H15ClFNPureza:99.17%Forma y color:SolidPeso molecular:275.75Mivebresib
CAS:<p>Mivebresib (ABBV-075) is a potent BET inhibitor with antitumor effects, disrupting gene expression and MYC, TMPRSS2-ETS proteins.</p>Fórmula:C22H19F2N3O4SPureza:98.74% - 99.32%Forma y color:SolidPeso molecular:459.47PHA-680632
CAS:<p>PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively.</p>Fórmula:C28H35N7O2Pureza:98.2%Forma y color:SolidPeso molecular:501.623-Aminobenzamide
CAS:<p>3-Aminobenzamide (PARP-IN-1) is an effective inhibitor of PARP (IC50<50 nM in CHO cells) and a mediator of oxidant-induced myocyte dysfunction during</p>Fórmula:C7H8N2OPureza:98.4% - 99.5%Forma y color:White To Off-White PowderPeso molecular:136.15SF2523
CAS:<p>SF2523 is a highly selective and potent inhibitor.</p>Fórmula:C19H17NO5SPureza:99.1% - 99.51%Forma y color:SolidPeso molecular:371.41JNJ-64619178
CAS:<p>JNJ-64619178: selective, oral, pseudo-irreversible PRMT5 inhibitor (IC50: 0.14 nM), effective in lung cancer.</p>Fórmula:C22H23BrN6O2Pureza:98.44% - 99.63%Forma y color:SolidPeso molecular:483.36GeA-69
CAS:<p>GeA-69 (GeA69) is a selective and allosteric PARP14 macrodomain 2 (MD2) inhibitor (Kd: 0.86 μM in ITC assays).</p>Fórmula:C20H16N2OPureza:99.85%Forma y color:SolidPeso molecular:300.35TTK21
CAS:<p>TTK21 is an activator of CBP/p300 histone acetyltransferase activity.</p>Fórmula:C17H15ClF3NO2Pureza:98.43%Forma y color:SolidPeso molecular:357.75PX-478
CAS:<p>PX-478 is a HIF-1α inhibitor with selectivity, oral activity, and blood-brain barrier permeability.</p>Fórmula:C13H20Cl4N2O3Pureza:97% - 99.79%Forma y color:SolidPeso molecular:394.12LW6
CAS:<p>LW6 (HIF-1α inhibitor) is a novel HIF-1 inhibitor.</p>Fórmula:C26H29NO5Pureza:98.1% - 98.22%Forma y color:SolidPeso molecular:435.51Dehydrocorydaline
CAS:<p>1.</p>Fórmula:C22H24NO4Pureza:99.84%Forma y color:SolidPeso molecular:366.43Belzutifan
CAS:<p>"Belzutifan (MK-6482) is an oral HIF-2α inhibitor for ccRCC, with enhanced potency (IC50: 9 nM)."</p>Fórmula:C17H12F3NO4SPureza:99.34% - 99.88%Forma y color:SolidPeso molecular:383.34I-BET151
CAS:<p>I-BET151 (GSK1210151A) (GSK1210151A) is a specific BET inhibitor for BRD2/3/4 (IC50: 0.5/0.25/0.79 μM, in cell-free assays).</p>Fórmula:C23H21N5O3Pureza:97.34% - 99.63%Forma y color:SolidPeso molecular:415.44Veliparib
CAS:<p>Veliparib (ABT-888) (ABT-888) is an orally bioavailable inhibitor of PARP (Kis: 5.2/2.9 nM for PARP1/2). It enhances apoptosis and autophagy.</p>Fórmula:C13H16N4OPureza:98.66% - 99%Forma y color:SolidPeso molecular:244.29Tranylcypromine hemisulfate
CAS:<p>Tranylcypromine hemisulfate (Tranylcypromine Sulfate) is an inhibitor of monoamine oxidase (MAO) and lysine-specific demethylase 1 (LSD1) with a rapid onset of</p>Fórmula:C9H11N1H2SO4Pureza:98% - 99.96%Forma y color:SolidPeso molecular:182.23SGI-1027
CAS:<p>SGI-1027 (DNA Methyltransferase Inhibitor II) is an effective and selective inhibitor of DNA methyltransferase (DNMT).</p>Fórmula:C27H23N7OPureza:99.45% - 99.78%Forma y color:SolidPeso molecular:461.52GSK467
CAS:<p>GSK467 is a potent and selective inhibitor of KDM5 (JARID1)(Ki : 10 nM).</p>Fórmula:C17H13N5O2Pureza:99.55%Forma y color:SolidPeso molecular:319.32MG 149
CAS:<p>MG 149 (Tip60 HAT inhibitor) is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).</p>Fórmula:C22H28O3Pureza:98.69% - 99.86%Forma y color:SolidPeso molecular:340.46UNC3866
CAS:<p>UNC3866 is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen.</p>Fórmula:C43H66N6O8Pureza:88.06% - 99.62%Forma y color:SolidPeso molecular:795.02GW779439X
CAS:<p>GW779439X is an inhibitor of CDK.</p>Fórmula:C22H21F3N8Pureza:97.87%Forma y color:SolidPeso molecular:454.45CCT241736
CAS:<p>CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3</p>Fórmula:C22H23Cl2N7Pureza:96.2% - 99.81%Forma y color:SolidPeso molecular:456.37G244-LM
CAS:<p>G244-LM is a potent and specific inhibitor of tankyrase 1/2. G244-LM inhibits Wnt signaling.</p>Fórmula:C18H22N4O3S2Pureza:98.46%Forma y color:SolidPeso molecular:406.52AMG 900
CAS:<p>AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM.</p>Fórmula:C28H21N7OSPureza:98.4% - 99.51%Forma y color:SolidPeso molecular:503.583-Methoxybenzamide
CAS:<p>3-Methoxybenzamide (3-MBA) is a competitive inhibitor of poly(ADP-ribose) synthetase.</p>Fórmula:C8H9NO2Pureza:98.52%Forma y color:SolidPeso molecular:151.16Amifostine trihydrate
CAS:<p>Amifostine trihydrate (WR2721) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.</p>Fórmula:C5H15N2O3PS·3H2OPureza:99.71% - 99.80%Forma y color:SolidPeso molecular:268.27Fosifidancitinib
CAS:<p>Fosifidancitinib is a potent inhibitor of JAK 1 and JAK 3.</p>Fórmula:C21H21FN5O7PPureza:99.54%Forma y color:SolidPeso molecular:505.39ARV-771
CAS:<p>ARV-771 is an effective BET degrader based on PROTAC technology.Cost-effective and quality-assured.</p>Fórmula:C49H60ClN9O7S2Pureza:99.69%Forma y color:SolidPeso molecular:986.64Oclacitinib maleate
CAS:<p>Oclacitinib maleate is a selective JAK inhibitor (IC50: 10-99 nM; JAK1 cytokines: 36-249 nM), with no effect on 38 non-JAK kinases.</p>Fórmula:C15H23N5O2S·C4H4O4Pureza:99.17%Forma y color:SolidPeso molecular:453.51CPI-169 racemate
CAS:<p>CPI-169 racemate (CPI 169) is a potent, and selective EZH2 inhibitor with IC50 of 0.24 nM, 0.51 nM, and 6.1 nM for EZH2 WT, EZH2 Y641N, and EZH1, respectively.</p>Fórmula:C27H36N4O5SPureza:99.59%Forma y color:SolidPeso molecular:528.66BET bromodomain inhibitor
CAS:<p>BET bromodomain inhibitor is a potent BET inhibitor.</p>Fórmula:C24H20ClN5O2Pureza:98.22% - 99.85%Forma y color:SolidPeso molecular:445.9BIX-01294 trihydrochloride
CAS:<p>BIX-01294 trihydrochloride is an inhibitor of G9a histone methyltransferase.In a cell-free assay, the IC50=2.7 μM for G9a histone methyltransferase.</p>Fórmula:C28H38N6O2·3HClPureza:99.41% - 99.95%Forma y color:SolidPeso molecular:600.02ENMD-2076
CAS:<p>ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.</p>Fórmula:C21H25N7Pureza:97.63% - ≥95%Forma y color:SolidPeso molecular:375.47
