Daño al ADN / Reparación del ADN
Los inhibidores de daño/ reparación del ADN son compuestos que interfieren con los procesos involucrados en la detección y reparación de daños en el ADN. Estos inhibidores son fundamentales para estudiar los mecanismos de estabilidad genómica, mutagénesis y respuesta al daño del ADN. También son importantes en la investigación del cáncer, ya que muchos tumores dependen de vías específicas de reparación del ADN para sobrevivir. Al inhibir estas vías, los inhibidores de daño/reparación del ADN pueden aumentar la eficacia de la quimioterapia y la radioterapia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de daño/reparación del ADN de alta calidad para apoyar su investigación en biología molecular, oncología y farmacología.
Subcategorías de "Daño al ADN / Reparación del ADN"
- ATM / ATR(71 productos)
- Alquilación de ADN(11 productos)
- ADN metiltransferasa(422 productos)
- ADN girasa(11 productos)
- ADN-PK(51 productos)
- MTH1(1 productos)
- Antimetabolito / análogo nucleósido(1.388 productos)
- Transcriptasa inversa(43 productos)
- Sirtuin(88 productos)
- Telomerasa(33 productos)
- Topoisomerasa(136 productos)
Mostrar 3 subcategorías más
Se han encontrado 959 productos de "Daño al ADN / Reparación del ADN"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
SR 2595
CAS:<p>SR2595 is an inverse agonist of nuclear receptor PPARγ with an IC 50 of 30 nM [1].</p>Fórmula:C37H38N2O3Forma y color:SolidPeso molecular:558.71BMS-250749
CAS:<p>BMS-250749 is a fluoroglycosylated fluoroindolocarbazole, it has antitumor activity.</p>Fórmula:C26H18F3N3O6Pureza:98%Forma y color:SolidPeso molecular:525.43HDAC6-IN-21
CAS:<p>HDAC6-IN-21 (compound 13) is an irreversible inhibitor of histone deacetylase 6 (HDAC6) [1].</p>Fórmula:C14H13F2N5O2Pureza:98%Forma y color:SolidPeso molecular:321.28DS-6930
CAS:<p>DS-6930 is an potent and selective PPAR γ Agonists with EC50 of 41 nM.</p>Fórmula:C23H21N3O4Forma y color:SolidPeso molecular:403.43CM-675
CAS:<p>CM-675 is a dual inhibitor of phosphodiesterase 5 (PDE5) and class I histone deacetylases (IC50s: 114 nM and 673 nM for PDE5 and HDAC1) with the potential to</p>Fórmula:C31H32N6O3Pureza:99.82%Forma y color:SolidPeso molecular:536.62SIRT6-IN-3
CAS:<p>SIRT6-IN-3 (compound 8a), a selective SIRT6 inhibitor (IC50 = 7.49 μM), impedes the proliferation of pancreatic ductal adenocarcinoma (PDAC) cells and prompts</p>Fórmula:C21H30Br3ClN6SPureza:98%Forma y color:SolidPeso molecular:673.73Makaluvamine A
CAS:<p>Makaluvamine A comes from the fruiting bodies of Didymium bahiense that act as active anti-cancer agents and DNA topo II inhibitors.</p>Fórmula:C11H11N3OForma y color:SolidPeso molecular:201.22Tankyrase-IN-5
CAS:<p>Tankyrase-IN-5 (Compound 30f), structurally related to MSC2504877, effectively inhibits tankyrase isoforms TNKS1 and TNKS2, with half-maximal inhibitory</p>Fórmula:C17H18N2O2Pureza:98%Forma y color:SolidPeso molecular:282.34SU-11752
CAS:<p>SU-11752 selectively inhibits DNA-PK by competing with ATP, enhances ionizing radiation sensitivity without affecting cell cycle or ATM activity.</p>Fórmula:C26H27N3O5SForma y color:SolidPeso molecular:493.57Pparδ agonist 1
CAS:<p>Pparδ agonist 1 is an agonist of PPAR-δ(EC50 of 5.06 nM).</p>Fórmula:C26H27NO5Pureza:98%Forma y color:SolidPeso molecular:433.5U-46619
CAS:<p>U-46619 is an effective thromboxane A2 (TXA2) agonist and a thromboxane A2 analog (endoperoxide), capable of inducing contraction in the aortic smooth muscle (</p>Fórmula:C21H34O4Pureza:98%Forma y color:SolidPeso molecular:350.49ATR-IN-20
<p>ATR-IN-20: potent ATR inhibitor, IC50=3nM; inhibits mTOR, IC50=18nM; selective vs PI3Kα, ATM, DNA-PK; good pharmacokinetics; anticancer.</p>Fórmula:C29H31N5O4SForma y color:SolidPeso molecular:545.65CAY10410
CAS:<p>CAY10410 is a PGD2/PGJ2 analog, modified for enhanced PPARγ activity and metabolic stability, non-toxic to SH-SY5Y cells at ≤25μM.</p>Fórmula:C20H30O3Forma y color:SolidPeso molecular:318.45LMP744 hydrochloride
CAS:<p>LMP744 hydrochloride (NSC-706744 hydrochloride) is a DNA intercalator and Topoisomerase I (Top1) inhibitor with antitumor activity. </p>Fórmula:C24H25ClN2O7Pureza:99.59% - 99.85%Forma y color:SolidPeso molecular:488.92AZ 5704
CAS:<p>ATM kinase inhibitor with 0.6 nM IC50, >600-fold selective, enhances irinotecan effects, oral use.</p>Fórmula:C23H23FN6O2Forma y color:SolidPeso molecular:434.479A1P9
CAS:<p>9A1P9, a multi-tail ionizable cationic phospholipid, facilitates membrane destabilization and is applicable for CRISPR-Cas9 gene editing in mice [1].</p>Fórmula:C27H58NO4PForma y color:SolidPeso molecular:491.73BO 2367
CAS:<p>BO 2367, a topoisomerase inhibitor, is used to suppress the growth of tumor .</p>Fórmula:C21H22ClF2N3O3Forma y color:SolidPeso molecular:437.87ATR-IN-22
CAS:<p>ATR-IN-22 (Compound 34), an orally active ATR inhibitor, exhibits potent anti-proliferative effects on MIAPaCa-2 cells with an IC50 value of less than 1 μM and</p>Fórmula:C25H31N7OPureza:98%Forma y color:SolidPeso molecular:445.56ATR-IN-5
CAS:<p>ATR-IN-5 is a potent inhibitor of ATR, a member of the PIKK family of proteins involved in genome stability and DNA damage repair.</p>Fórmula:C27H32F3N9OForma y color:SolidPeso molecular:555.6Topoisomerase I inhibitor 9
CAS:<p>Topoisomerase I Inhibitor 9 (compound 3d), a specific inhibitor of leishmanial topoisomerase IB, exhibits antileishmanial activity, demonstrating an IC50 value</p>Fórmula:C23H15Br2FN2Pureza:98%Forma y color:SolidPeso molecular:498.19
