Daño al ADN / Reparación del ADN
Los inhibidores de daño/ reparación del ADN son compuestos que interfieren con los procesos involucrados en la detección y reparación de daños en el ADN. Estos inhibidores son fundamentales para estudiar los mecanismos de estabilidad genómica, mutagénesis y respuesta al daño del ADN. También son importantes en la investigación del cáncer, ya que muchos tumores dependen de vías específicas de reparación del ADN para sobrevivir. Al inhibir estas vías, los inhibidores de daño/reparación del ADN pueden aumentar la eficacia de la quimioterapia y la radioterapia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de daño/reparación del ADN de alta calidad para apoyar su investigación en biología molecular, oncología y farmacología.
Subcategorías de "Daño al ADN / Reparación del ADN"
- ATM / ATR(71 productos)
- Alquilación de ADN(11 productos)
- ADN metiltransferasa(422 productos)
- ADN girasa(11 productos)
- ADN-PK(51 productos)
- MTH1(1 productos)
- Antimetabolito / análogo nucleósido(1.388 productos)
- Transcriptasa inversa(43 productos)
- Sirtuin(88 productos)
- Telomerasa(33 productos)
- Topoisomerasa(136 productos)
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Se han encontrado 958 productos de "Daño al ADN / Reparación del ADN"
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Epigenetic factor-IN-1
CAS:<p>Epigenetic factor-IN-1 (40569Z) is an epigenetic factor inhibitor that exhibits potent binding affinity for SIRT7.</p>Fórmula:C32H34FN5O6S2Pureza:98%Forma y color:SolidPeso molecular:667.77PR-104A
CAS:<p>PR-104A is a hypoxia-targeted anticancer agent.</p>Fórmula:C14H19BrN4O9SForma y color:SolidPeso molecular:499.29ATM-IN-1
CAS:<p>ATM-IN-1 is a potent inhibitor of ATM. ATM-IN-1 has shown research potential in cancer and neurological diseases.</p>Fórmula:C30H36N6O3Forma y color:SolidPeso molecular:528.65Pradofloxacin
CAS:<p>Pradofloxacin is a fluoroquinolone antibioticthat exerts its bactericidal effect by inhibiting bacterial DNA gyrase and topoisomerase IV.</p>Fórmula:C21H21FN4O3Pureza:98.76%Forma y color:SolidPeso molecular:396.41DNMT-IN-3
CAS:<p>DNMT-IN-3 is a DNA Methyltransferase (DNMT) inhibitor with an IC50 of 60 nM against Plasmodium falciparum (Plasmodium), demonstrating antimalarial activity and suitability for malaria-related research [1].</p>Fórmula:C37H39N7OForma y color:SolidPeso molecular:597.75MPI_5a
CAS:<p>MPI_5a selectively inhibits HDAC6 (IC50=36 nM), slightly affects other HDACs, and blocks acyl-tubulin build-up (IC50=210 nM).</p>Fórmula:C16H17N3O3Pureza:99.62%Forma y color:SolidPeso molecular:299.32DNA-PK-IN-10
CAS:<p>DNA-PK-IN-10 is a DNA-PK inhibitor utilized in the research of breast cancer and non-small cell lung cancer [1].</p>Fórmula:C25H28N6O2Pureza:98%Forma y color:SolidPeso molecular:444.539-Chloromethyl-10-hydroxy-11-F-Camptothecin
CAS:<p>9-Chloromethyl-10-hydroxy-11-F-Camptothecin, a novel derivative of camptothecin, functions as a DNA topoisomerase I (Topo I) inhibitor with potential</p>Fórmula:C22H18ClFN2O4Pureza:98%Forma y color:SolidPeso molecular:428.84SRT3657
CAS:<p>SRT3657 is a brain-permeable SIRT1 activator, has neuroprotective effect.</p>Fórmula:C40H54N8O6SPureza:98%Forma y color:SolidPeso molecular:774.97NH2-methylpropanamide-Exatecan TFA
CAS:<p>Exatecan TFA, a methylpropanamide-modified derivative of the common ADC cytotoxin Exatecan, serves as a DNA topoisomerase I inhibitor with an IC50 of 2.2 μM (0.</p>Fórmula:C30H30F4N4O7Pureza:98%Forma y color:SolidPeso molecular:634.58DY-46-2
CAS:<p>DY-46-2 is a DNMT3A inhibitor (IC50: 0.39 ± 0.23 μM) with anticancer activity and is used in cancer and tumor research.</p>Fórmula:C19H22N6O5SPureza:99.12% - 99.12%Forma y color:SolidPeso molecular:446.48HDAC/BET-IN-1
CAS:<p>HDAC/BET-IN-1 inhibits HDAC1 (IC50: 0.163 μM), HDAC6 (IC50: 0.067 μM), BRD4 (Ki: 0.076 μM), and fights leukemia.</p>Fórmula:C29H40N4O8SPureza:98%Forma y color:SolidPeso molecular:604.71Trovafloxacin mesylate
CAS:<p>Trovafloxacin: broad-spectrum fluoroquinolone, blocks DNA gyrase/topoisomerase IV and PANX1 channel (IC50=4μM).</p>Fórmula:C21H19F3N4O6SPureza:99.18%Forma y color:SolidPeso molecular:512.46NT160
CAS:<p>NT160 is a fluorinated radioactive compound, a potent class IIa histone deacetylase (HDAC) inhibitor, used in the study of neurological diseases.</p>Fórmula:C21H21F3N4O2Pureza:99.3%Forma y color:SolidPeso molecular:418.41Antipsychotic agent 54
CAS:<p>Telomerase-IN-1 is a telomerase inhibitor (IC50: 0.19 μM).</p>Fórmula:C21H23FN2O4Pureza:98.10%Forma y color:SolidPeso molecular:386.42HDAC6-IN-8
CAS:<p>Compound 12C, with altered cap groups, shows wide-range enzyme inhibition; 9m and 9q target HDAC6 specifically.</p>Fórmula:C23H17BrFN5O3Pureza:98%Forma y color:SolidPeso molecular:510.32Bocodepsin
CAS:<p>Bocodepsin (OKI-179) is a selective, orally active inhibitor of histone deacetylases (HDAC) with demonstrated antitumor efficacy.</p>Fórmula:C26H39N5O6S2Pureza:98%Forma y color:SolidPeso molecular:581.75ATR-IN-29
CAS:<p>ATR-IN-29, a potent, orally active inhibitor of ATR kinase, exhibits an IC50 of 1 nM and demonstrates antiproliferative activity [1].</p>Fórmula:C19H22N8OPureza:98%Forma y color:SolidPeso molecular:378.43Zabofloxacin
CAS:<p>Zabofloxacin inhibits bacterial topoisomerases II/IV, effectively targeting gram-positive pathogens like S. aureus and S. pneumoniae.</p>Fórmula:C19H20FN5O4Pureza:98%Forma y color:SolidPeso molecular:401.3910-Nitrolinoleic acid
CAS:<p>10-Nitrolinoleate, a nitration product of linoleate, modulates PPARγ, enhancing glucose uptake, and aids in muscle relaxation via NO/cGMP pathway.</p>Fórmula:C18H31NO4Forma y color:SolidPeso molecular:325.44
