Daño al ADN / Reparación del ADN

Los inhibidores de daño/ reparación del ADN son compuestos que interfieren con los procesos involucrados en la detección y reparación de daños en el ADN. Estos inhibidores son fundamentales para estudiar los mecanismos de estabilidad genómica, mutagénesis y respuesta al daño del ADN. También son importantes en la investigación del cáncer, ya que muchos tumores dependen de vías específicas de reparación del ADN para sobrevivir. Al inhibir estas vías, los inhibidores de daño/reparación del ADN pueden aumentar la eficacia de la quimioterapia y la radioterapia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de daño/reparación del ADN de alta calidad para apoyar su investigación en biología molecular, oncología y farmacología.

Subcategorías de "Daño al ADN / Reparación del ADN"

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Se han encontrado 958 productos de "Daño al ADN / Reparación del ADN"

Pureza (%)

100

productos por página.

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WAY-354574
CAS:
- 851873-40-0
WAY-354574 is an active compound that targets the deacetylase Sirtuin, utilized in research focused on Huntington's disease (HD) [1].
Fórmula:C₂₀H₂₃ClN₂O₃S
Pureza:98%
Forma y color:Solid
Peso molecular:406.93
Ref: TM-T80813
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PARP7-IN-16
CAS:
- 2435657-10-4
PARP7-IN-16 (compound 36) is a potent, selective, and orally active PARP-1/2/7 inhibitor, exhibiting IC50 values of 0.94, 0.87, and 0.21 nM , respectively.
Fórmula:C₂₅H₂₆FN₄NaO₄
Pureza:98%
Forma y color:Solid
Peso molecular:488.49
Ref: TM-T81541
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SDOX
CAS:
- 2921601-78-5
SDOX, a prodrug, releases Doxorubicin selectively in high-GSH tumor cells, minimizing harm to healthy tissue.
Fórmula:C₆₉H₉₇NO₂₀S₂
Pureza:98%
Forma y color:Solid
Peso molecular:1324.63
Ref: TM-T74364
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Furegrelate sodium
CAS:
- 85666-17-7
Furegrelate sodium (U-63557A) is an orally active thromboxane synthase inhibitor with an IC50 of 15 nM in platelets.
Fórmula:C₁₅H₁₀NNaO₃
Pureza:99.92%
Forma y color:Solid
Peso molecular:275.23
Ref: TM-T11339
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Lexitropsin 1
CAS:
- 123725-00-8
Lexitropsin 1 is a new anticancer drug.
Fórmula:C₁₅H₁₉N₇O₃S
Pureza:98%
Forma y color:Solid
Peso molecular:377.42
Ref: TM-T25704
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7-Deaza-2′-deoxyguanosine 5′-triphosphate
CAS:
- 101515-08-6
7-Deaza-2′-deoxyguanosine 5′-triphosphate (7-Deaza-2'-dGTP), a nucleotide analogue, functions as a telomerase inhibitor with an IC50 value of 11 μM [1].
Fórmula:C₁₁H₁₇N₄O₁₃P₃
Pureza:98%
Forma y color:Solid
Peso molecular:506.19
Ref: TM-T83248
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(S)-Ceralasertib
CAS:
- 1352226-87-9
(S)-Ceralasertib: Potent, selective ATR inhibitor with strong preclinical physicochemical and PK profiles.
Fórmula:C₂₀H₂₄N₆O₂S
Forma y color:Solid
Peso molecular:412.51
Ref: TM-T12795
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ATR-IN-18
CAS:
- 2766407-55-8
ATR-IN-18: oral ATR inhibitor, IC50 0.69 nM; halts LoVo cell growth, IC50 37.34 nM; anti-tumor.
Fórmula:C₁₉H₂₂F₃N₇O₅S
Forma y color:Solid
Peso molecular:517.48
Ref: TM-T63604
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Prostaglandin B3
CAS:
- 36614-32-1
Prostaglandin B3 (PGB3) is a secondary alcohol belonging to the prostaglandin B class, characterized by its relatively low affinity for human PPARγ, exhibiting a K_i value greater than 1 mM, in contrast to PGB1 and PGB2, which have K_i values of 26.28 ± 8.7 μM and 77 ± 37.7 μM, respectively [1].
Fórmula:C₂₀H₂₈O₄
Forma y color:Solid
Peso molecular:332.43
Ref: TM-T84583
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Ambamustine
CAS:
- 85754-59-2
Ambamustine (PTT 119): a tripeptide nitrogen mustard, DNA inhibitor/alkylator with antitumor properties, researched for various disorders.
Fórmula:C₂₉H₃₉Cl₂FN₄O₄S
Pureza:98%
Forma y color:Solid
Peso molecular:629.61
Ref: TM-T25073
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ATR-IN-8
CAS:
- 2672511-20-3
ATR-IN-8 is a potent inhibitor of ATR. ATR-IN-8 has shown potential research value in cancer diseases.
Fórmula:C₂₀H₂₂N₆O₂S
Forma y color:Solid
Peso molecular:410.49
Ref: TM-T62084
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Oxamflatin
CAS:
- 151720-43-3
Oxamflatin (Metacept-3) is a selective histone deacetylase (HDAC) inhibitor with an alkyne group capable of azide-alkyne cycloaddition reactions (CuAAc).
Fórmula:C₁₇H₁₄N₂O₄S
Pureza:98.25%
Forma y color:Solid
Peso molecular:342.37
Ref: TM-T16415
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KD-3010
CAS:
- 934760-92-6
KD-3010 (Kalypsys) is an orally active potent and selective PPARδ agonist for the study of liver injury.
Fórmula:C₃₀H₃₃F₃N₂O₈S₂
Pureza:99.61%
Forma y color:Solid
Peso molecular:670.72
Ref: TM-T11747
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Nesuparib
CAS:
- 2055357-64-5
Nesuparib, a potent PARP/TNKS1 inhibitor, has antitumor properties and potential for treating various diseases.
Fórmula:C₂₃H₂₄N₆O
Pureza:99.71%
Forma y color:Solid
Peso molecular:400.48
Ref: TM-T61932
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KPZ560
CAS:
- 2397562-43-3
KPZ560, a potent HDAC 1 and HDAC 2 inhibitor, exhibits IC50 values of 12 nM and 68 nM, respectively.
Fórmula:C₂₆H₂₁N₅O₃S₂
Pureza:98%
Forma y color:Solid
Peso molecular:515.61
Ref: TM-T81974
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AZD4619
CAS:
- 1067247-60-2
AZD4619 is a potent, selective and reversible orally bioavailable agonist of PPARα receptor.
Fórmula:C₂₅H₂₆O₈S₂
Forma y color:Solid
Peso molecular:518.6
Ref: TM-T26716
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BM152054
CAS:
- 213411-84-8
BM152054 is a potent PPARγ ligand that induces glucose utilization in peripheral tissues by enhancing insulin action.
Fórmula:C₂₂H₁₈N₂O₄S₃
Pureza:99.56%
Forma y color:Solid
Peso molecular:470.58
Ref: TM-T19211
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Sipoglitazar
CAS:
- 342026-92-0
Sipoglitazar, a PPARγ agonist, is used potentially for the treatment of diabetes.
Fórmula:C₂₅H₂₅N₃O₄S
Pureza:98%
Forma y color:Solid
Peso molecular:463.55
Ref: TM-T28783
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Sirtuin modulator 1
CAS:
- 2070015-26-6
Sirtuin modulator 1 (SRT3025 Hydrochloride) is a modulator of SIRT1 with EC1.5 of < 1 μM.
Fórmula:C₃₁H₃₂ClN₅O₂S₂
Pureza:99.63%
Forma y color:Solid
Peso molecular:606.2
Ref: TM-T12922
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SIRT-IN-1
CAS:
- 1431411-60-7
SIRT-IN-1 is a potent SIRT1/2/3 inhibitor(IC50s of 15, 10, 33 μM, respectively).
Fórmula:C₁₉H₂₇N₅O₂S
Pureza:99.29%
Forma y color:Solid
Peso molecular:389.52
Ref: TM-T12918