RAAS
Los inhibidores del sistema renina-angiotensina-aldosterona (RAAS) son compuestos que se dirigen a la vía del RAAS, conocida principalmente por su papel en la regulación de la presión arterial y el equilibrio de líquidos, pero que también influye en la angiogénesis. La vía del RAAS puede contribuir al desarrollo de nuevos vasos sanguíneos en los tumores, apoyando así su crecimiento. Inhibir los componentes del RAAS puede, por lo tanto, tener efectos antiangiogénicos, lo que convierte a estos inhibidores en herramientas valiosas en el tratamiento de ciertos cánceres y trastornos vasculares. En CymitQuimica, ofrecemos una gama de inhibidores de alta calidad del RAAS para apoyar su investigación en biología cardiovascular, oncología y angiogénesis.
Se han encontrado 87 productos de "RAAS"
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Handle region peptide, rat
CAS:<p>Rat handle region peptide acts as prorenin receptor blocker, curbs diabetic kidney disease, and reduces eye inflammation.</p>Fórmula:C54H101N15O12SPureza:98%Forma y color:SolidPeso molecular:1184.54Azilsartan Medoxomil Potassium
CAS:<p>Azilsartan Medoxomil Potassium (TAK-491 Potassium) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.</p>Fórmula:C30H23N4O8·KPureza:98.72%Forma y color:SolidPeso molecular:606.62Aclerastide
CAS:<p>Aclerastide, an angiotensin receptor agonist, decreases fibrosis in wounds; effect increases with use duration, blocked by AT antagonist.</p>Fórmula:C42H64N12O11Forma y color:SolidPeso molecular:913.03Brain Natriuretic Peptide (1-32), rat
CAS:<p>Rat Brain Natriuretic Peptide (1-32) is a 32-amino-acid peptide from heart, released when ventricles stretch excessively.</p>Fórmula:C146H239N47O44S3Pureza:98%Forma y color:SolidPeso molecular:3452.94PRO20
<p>PRO20 is a specific and competitive antagonist of the (pro)renin receptor (PRR). It inhibits the calcium influx induced by Proproin with an IC50 value of 81 nmol/L. By blocking the binding of Prorenin to PRR, PRO20 inhibits the activation of the renin-angiotensin system (RAS), reducing the production of angiotensin II (Ang II) and exerting antihypertensive effects. PRO20 holds promise for research in antihypertensive agents.</p>Forma y color:Odour SolidTetrahydro Aldosterone
CAS:<p>Tetrahydro Aldosterone is a steroidal compound that inhibits the adrenal angiotensin II receptor, with an IC50 of 10 μM.</p>Fórmula:C21H32O5Forma y color:SolidPeso molecular:364.48Angiotensin II (1-4), human
CAS:<p>Angiotensin II constricts blood vessels and boosts blood pressure by escalating norepinephrine release.</p>Fórmula:C24H37N7O8Pureza:98%Forma y color:SolidPeso molecular:551.59Angiotensin II (1-4), human TFA
<p>Angiotensin II is a potent direct vasoconstrictor, causing arteries and veins to constrict, so leading to an increase in blood pressure.</p>Fórmula:C26H38F3N7O10Pureza:98%Forma y color:SolidPeso molecular:665.62Renin FRET Substrate I
CAS:Renin FRET Substrate I, designed for human renin, contains angiotensinogen's N-terminal cleavage site.Fórmula:C90H120N22O16SPeso molecular:1798.15BIBS 39
CAS:<p>BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist.</p>Fórmula:C32H36N4O3Pureza:99.28%Forma y color:SolidPeso molecular:524.65C-Type Natriuretic Peptide (1-53), human
CAS:<p>CNP, from natriuretic family, first in pigs, now in other species, processes into CNP-22/CNP-53, similar to ANP/BNP, with varying potencies.</p>Fórmula:C251H417N81O71S3Pureza:98%Forma y color:SolidPeso molecular:5801.77Angiotensin amide
CAS:<p>Angiotensin amide, an octapeptide amide, can be used to increase blood pressure by vasoconstriction.</p>Fórmula:C49H70N14O11Pureza:98%Forma y color:SolidPeso molecular:1031.17[Sar1, Ile8]-Angiotensin II
CAS:<p>[Sar1, Ile8]-Angiotensin II(3TFA) is a peptide that has multiple effects on vascular smooth muscle.</p>Fórmula:C46H73N13O10Pureza:98%Forma y color:SolidPeso molecular:968.15Angiotensin II (5-8), human
CAS:<p>Angiotensin II (5-8) is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II</p>Fórmula:C26H36N6O5Pureza:98%Forma y color:SolidPeso molecular:512.6Losartan (D4 Carboxylic Acid)
CAS:<p>Losartan D4 Carboxylic Acid is the deuterium labeled Losartan, which is an angiotensin II receptor antagonist.</p>Fórmula:C22H21ClN6O2Pureza:98%Forma y color:SolidPeso molecular:440.92PD 123319 ditrifluoroacetate
CAS:<p>PD 123319 ditrifluoroacetate is a selective non-peptide AT2 receptor antagonist with IC50 of 34 nM.</p>Fórmula:C35H34F6N4O7Pureza:98%Forma y color:SolidPeso molecular:736.66Candesartan-d4
CAS:<p>Candesartan D4 is the deuterium labeled Candesartan. Candesartan is an antagonist of angiotensin II receptor.</p>Fórmula:C24H20N6O3Pureza:98%Forma y color:SolidPeso molecular:444.48Olmesartan-d4
CAS:<p>Olmesartan D4 is the deuterium labeled Olmesartan. Olmesartan is an antagonist of angiotensin II receptor (AT1R) used to treat high blood pressure.</p>Fórmula:C24H26N6O3Pureza:98%Forma y color:SolidPeso molecular:450.53Valsartan-d9
CAS:<p>Valsartan D9: deuterium-labeled, angiotensin II receptor antagonist, treats hypertension & heart failure.</p>Fórmula:C24H29N5O3Pureza:98%Forma y color:SolidPeso molecular:444.57Azilsartan-d5
CAS:<p>Azilsartan (TAK-536) D5 is the deuterium-labeled Azilsartan. Azilsartan is a specific antagonist of the angiotensin II type 1 receptor.</p>Fórmula:C25H20N4O5Pureza:98%Forma y color:SolidPeso molecular:461.48
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