Reductasa

Finasteride is an oral inhibitor of active testosterone 5-alpha-reductase and Ki value is 10 nM.

Epalrestat, an aldose reductase inhibitor, is well tolerated in Long-term therapy. It can effectually ameliorate …

Aldose reductase-IN-1 is a aldose reductase inhibitor (IC50: 28.9 pM).

Isoliquiritigenin, an anti-tumor flavonoid from the root of Glycyrrhiza glabra, suppresses aldose reductase (IC50=320 nM).

Methotrexate is a folate analog metabolic inhibitor with immunosuppressant and antineoplastic properties.

Dutasteride is a 5-alpha-reductase inhibitor that inhibits both type-1 and type2 isoforms of the enzyme …

Imirestat is an aldose reductase inhibitor that can be used in diabetes research.

AT-007 is an orally active CNS penetrant Aldose Reductase inhibitor for the treatment of Galactosemia …

Fluvastatin sodium, a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol …

Trimethoprim is a Dihydrofolate Reductase Inhibitor Antibacterial. The mechanism of action of trimethoprim is as …

Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor (IC50: 3.3 μM). …

8-Lavandulylkaempferol exhibits significant inhibitory effects with IC(50) values of 7.10 and 8.11 microM for butyrylcholinesterase …

Caracemide inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer …

Danshenol A has strong aldose reductase (AR) inhibitory activity, has IC50 of 0.10 microM which …

Tolrestat is a potent inhibitor of aldose reductase (IC50 = 35 nM).

Vicenin-1 possesses potent anti-inflammatory and anti-oxidant activity.

Torilin is an inhibitor of testosterone 5 alpha-reductase, it (IC50 = 31.7 +/- 4.23 microM) …

12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, …

1. Engeletin may serve as a potential anti-inflammatory agent. 2. Engeletin possesses potent inhibition of …

Alrestatin is a specific inhibitor of aldose reductase and attenuates glucose-induced angiotensin II production in …

Sulindac sulfone is a metabolite of the nonsteroidal anti-inflammatory drug sulindac. Sulindac sulfone is an …

Ponalrestat is an aldose reductase inhibitor.

Endogenous estrogen receptor ligand (Ki values are 0.2 and 1.2 nM for ERα and ERβ …

BYAKANGELICIN,a main furanocoumarin constituent isolated and characterized as an aldose reductase inhibitor,and is effective for …

EBPC is an inhibitor of aldose reductase.

1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT).

Pralatrexate is a folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibiting high affinity for reduced …

Zopolrestat is a potent inhibitor of aldose reductase (IC50 = 3.1 nM).

Tectoridin possesses an estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors. …

Sorbinil is an Aldose reductase inhibitor. Sorbinil plays a therapeutic role in treating diabetes and …

Ganoderic acid C2 has anti-inflammatory,and anti-tumor-promoting activities. Ganoderic acid C2 can inhibit histamine release, it …

COH29 is an orally available, aromatically substituted thiazole and inhibitor of the human ribonucleotide reductase …

Fanotaprim is a dihydrofolate reductase (DHFR) inhibitor. Fanotaprim inhibits the growth of T. gondii strains …

Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects. Aurothiomalate …

Poliumoside is a natural compound which exhibits significant inhibition of advanced glycation end product formation …

Acid Yellow 36 is an azo dye and a pH indicator. Acid Yellow 36 changes …

Gonadorelin Acetate is hypothalamic neuropeptide which plays a key role in the control of reproductive …

2'-Acetylacteoside has antioxidative activity. It can significantly attenuate glutamate-induced neurotoxicity at concentrations ranging from 0.1 …

2-Chloro-1-(4-fluorobenzyl)benzimidazole is an inhibitor of aldose reductase (ALR2).

Glyceraldehyde is produced from the action of the enzyme glyceraldehyde dehydrogenase, which converts glycerol to …

GinsenosideRo exhibits a Ca2+-antagonistic antiplatelet effect.

AKR1C3-IN-4 is a potent and selective inhibitor of aldo-keto reductase 1C3 (AKR1C3) with an IC50 …

Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor

AY 9944 is a specific cholesterol biosynthesis inhibitor. AY 9944 inhibits the 7-dehydro cholesterol Δ7-reductase …

Fidarestat is an aldose reductase inhibitor (IC50s: 26 nM, 33 μM, and 1.8 μM for …