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Inmunología e inflamación

Inmunología e inflamación

Los inhibidores de inmunología e inflamación son compuestos que modulan la respuesta inmunitaria y los procesos inflamatorios. Estos inhibidores son cruciales para estudiar los mecanismos de regulación inmunitaria, la autoinmunidad y la inflamación crónica, así como para desarrollar tratamientos para enfermedades inflamatorias, alergias y trastornos relacionados con el sistema inmunológico. Al dirigirse a vías clave en el sistema inmunológico, estos inhibidores pueden ayudar a reducir las respuestas inmunitarias excesivas o inadecuadas. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad para apoyar su investigación en inmunología, inflamación y desarrollo terapéutico.

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Se han encontrado 3055 productos de "Inmunología e inflamación"

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  • Antitumor agent-185


    <p>Antitumor agent-185 (compound 3) exhibits significant antitumor effects, effectively inhibiting tumor growth and extending the survival period of mice in vivo.</p>
    Fórmula:C109H199N5O36P2
    Forma y color:Solid
    Peso molecular:2217.71
  • Reltecimod

    CAS:
    Reltecimod, a CD28 antigen inhibitor, is used potentially for the treatment of necrotizing soft tissue infection.
    Fórmula:C46H72N10O15S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1037.19
  • Miptenalimab

    CAS:
    <p>Miptenalimab (BI-754111) is an anti-human LAG-3 antibody with a dissociation constant (K D) of 88.6 nM for h LAG-3, effectively blocking the interaction between</p>
    Forma y color:Liquid
  • PMX 205

    CAS:
    <p>PMX 205 is an effective complement antagonist of the C5a receptor.</p>
    Fórmula:C45H62N10O6
    Pureza:98%
    Forma y color:Solid
    Peso molecular:839.04
  • Nemvaleukin alfa

    CAS:
    <p>Nemvaleukin alfa (ALKS 4230) is an interleukin 2 fusion protein that is a selective agonist of the medium-affinity IL-2 receptor.</p>
    Pureza:98.4% (SDS-PAGE); 98.3% (SEC-HPLC) - 98.4% (SDS-PAGE); 98.3% (SEC-HPLC)
    Forma y color:Liquid
  • 3-O-(2'E,4'Z-Decadienoyl)ingenol


    <p>3-O-(2'E,4'Z-Decadienoyl)ingenol is a useful organic compound for research related to life sciences and the catalog number is T124104.</p>
    Fórmula:C30H42O6
    Forma y color:Solid
    Peso molecular:498.66
  • cGAMP diammonium


    <p>cGAMP is a second messenger that triggers interferon production via STING activation upon detecting cytosolic DNA.</p>
    Fórmula:C20H30N12O13P2
    Forma y color:Solid
    Peso molecular:708.47
  • TLQP-21

    CAS:
    <p>TLQP 21, a VGF-derived peptide, guards CGCs against apoptosis and combats early diet-induced diabetes by boosting energy spend.</p>
    Fórmula:C107H170N40O26
    Pureza:98%
    Forma y color:Solid
    Peso molecular:2432.75
  • Isorabaichromone

    CAS:
    <p>Isorabaichromone exhibits potent antioxidative properties, including DPPH radical and superoxide anion scavenging activities [1].</p>
    Fórmula:C29H32O12
    Pureza:98%
    Forma y color:Solid
    Peso molecular:572.56
  • Eritoran

    CAS:
    <p>Eritoran: TLR4 antagonist; shields mice from lethal influenza, EBOV, MARV; reduces granulocytosis, eases cytokine storm.</p>
    Fórmula:C66H126N2O19P2
    Forma y color:Solid
    Peso molecular:1313.66
  • Biotin-labeled ODN 2395 sodium


    <p>Biotin-labeled ODN 2395 (sodium), a Class C oligodeoxynucleotide and TLR9 agonist, serves to assess cellular uptake and localization of CpG ODN through a biotin</p>
    Forma y color:Odour Solid
  • Ara-F-NAD+

    CAS:
    <p>Ara-F-NAD+, an arabino analogue of NAD + , is a potent, slow-binding CD38 NADase inhibitor, with a K i of 169 nM.</p>
    Fórmula:C21H26FN7O13P2
    Forma y color:Solid
    Peso molecular:665.421
  • 3-(3-Methoxyphenyl)acrylic acid

    CAS:
    <p>3-(3-Methoxyphenyl)acrylic acid can inhibit free radical generation, has antioxidant potential, and can be used in biochemical experiments and drug synthesis.</p>
    Fórmula:C10H10O3
    Pureza:99.91%
    Forma y color:Solid
    Peso molecular:178.19
  • CP-289

    CAS:
    <p>CP-289 is a potent C5a receptor antagonist with IC50 of 1 μM.</p>
    Fórmula:C30H35ClN2O2
    Pureza:99.97%
    Forma y color:Soild
    Peso molecular:491.06
  • Schisanchinin D

    CAS:
    <p>Schisanchinin D is a useful organic compound for research related to life sciences. The catalog number is T125682 and the CAS number is 1614245-13-4.</p>
    Fórmula:C23H30O6
    Forma y color:Solid
    Peso molecular:402.487
  • Amfenac sodium

    CAS:
    <p>Amfenac is a nonsteroidal anti-inflammatory drug. Amfenac also has acetic acid moiety.</p>
    Fórmula:C15H12NNaO3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:277.26
  • Antibacterial agent 273


    <p>Antibacterialagent 273 (Compound 15e) is an antimicrobial agent targeting bacterial cell membranes, effectively disrupting them with a MIC value of 4 μg/mL against Staphylococcus aureus. It causes the leakage of intracellular nucleic acids and proteins, inhibits bacterial metabolic activity, and induces the accumulation of reactive oxygen species (ROS) within bacteria. Antibacterialagent 273 is applicable in research on infections caused by Staphylococcus aureus.</p>
    Forma y color:Odour Solid
  • TLR8 agonist 2

    CAS:
    <p>TLR8 agonist 2 activates human TLR8 (EC50=3nM), less effective on TLR7 (EC50=33.33μM).</p>
    Fórmula:C16H22N8
    Forma y color:Solid
    Peso molecular:326.408
  • diABZI-C2-NH2

    CAS:
    <p>diABZI-C2-NH2 is an agonist of the interferon gene STING, which modulates STING-dependent type I interferon production.</p>
    Fórmula:C36H43N13O4
    Pureza:96.09%
    Forma y color:Solid
    Peso molecular:721.81
  • Keap1-Nrf2-IN-9

    CAS:
    <p>Keap1-Nrf2-IN-9 inhibits Keap1-Nrf2 PPI with 0.575 µM IC50, boosts Nrf2 genes, non-toxic in ARPE19 cells.</p>
    Fórmula:C31H30N2O11S2
    Forma y color:Solid
    Peso molecular:670.71
  • Piperkadsin A

    CAS:
    <p>Piperkadsin A effectively inhibits reactive oxygen species (ROS) production, specifically targeting PMA-induced ROS in human polymorphonuclear neutrophils,</p>
    Fórmula:C21H24O5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:356.41
  • ARC186


    <p>ARC186 is a highly potent aptamer that serves as a complement inhibitor by blocking the convertase-catalyzed activation of C5.</p>
    Forma y color:Solid
    Peso molecular:120702.76
  • FAPI-46

    CAS:
    <p>FAPI-46 is a radiotracer for fibroblast activation protein (FAP),conjugated with 68Ga or 177Lu tracer for FAP tumours in positron emission tomography (PET).</p>
    Fórmula:C41H57F2N11O9
    Forma y color:Solid
    Peso molecular:885.96
  • RDR03785

    CAS:
    <p>The MIF Antagonist IV, RDR 03785 controls the biological activity of MIF. This small molecule/inhibitor is primarily used for Cell Structure applications.</p>
    Fórmula:C19H18F3NO4
    Pureza:98.92%
    Forma y color:Solid
    Peso molecular:381.35
  • 12-Oxo phytodienoic acid

    CAS:
    <p>12-oxo PDA boosts alkaloid production in E. californica, enhances B. dioica tendril curls, and blocks JA-induced cell death in A. fru mutants.</p>
    Fórmula:C18H28O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:292.41
  • Anti-inflammatory agent 7


    <p>Anti-inflammatory Agent 7 suppresses proinflammatory cytokines by hindering the NF-κB/MAPK signaling pathway in both LPS-treated RAW 264.7 cells and mice.</p>
    Fórmula:C36H40N4O9
    Forma y color:Solid
    Peso molecular:672.72
  • Cartap hydrochloride

    CAS:
    <p>Cartap hydrochloride is an insecticidal derivative. It is used to control chewing and sucking insects on many crops.</p>
    Fórmula:C18H33Cl2CuN3O3
    Forma y color:Colorless Crystalline Slightly Hygroscopic Solid Coa
    Peso molecular:473.93
  • MTvkPABC-P5 TFA


    <p>MTvkPABC-P5d TFA, a TLR7 agonist, functions as an immune stimulant. It is applicable in the synthesis of immune-stimulating antibody conjugates (ISAC).</p>
    Forma y color:Odour Solid
  • Galectin-8-IN-2

    CAS:
    <p>Galectin-8-IN-2 (Compound 10) acts as an inhibitor of galectin-8N [1].</p>
    Fórmula:C15H20O7
    Forma y color:Solid
    Peso molecular:312.32
  • Chitohexaose hexahydrochloride

    CAS:
    <p>Chitohexaose hexahydrochloride, a TLR4-inhibiting chitosan derivative, blocks LPS-induced inflammation.</p>
    Fórmula:C36H74Cl6N6O25
    Forma y color:Solid
    Peso molecular:1203.71
  • 3-Methoxycatechol

    CAS:
    <p>3-Methoxycatechol: lignin-based, esophageal carcinogen. 1,2-Dihydroxy-3-methoxybenzene: potent anti-EMCV.</p>
    Fórmula:C7H8O3
    Pureza:99.31%
    Forma y color:Solid
    Peso molecular:140.14
  • N188 TFA


    <p>N188 TFA is a radiolabeled ligand based on a bicyclic peptide scaffold, targeting the protein nectin-4, which is overexpressed in various tumors. It can be efficiently labeled with the radioactive isotope 68Ga to form 68Ga-N188, suitable for positron emission tomography (PET) imaging. The development of N188 TFA and its radiolabeled form, 68Ga-N188, holds potential for the diagnosis and treatment of cancers such as urothelial carcinoma.</p>
    Forma y color:Odour Solid
  • Perfluorododecanoic acid

    CAS:
    <p>Perfluorododecanoic acid (PFDoA) is a PFAS pollutant causing ROS increase, mitochondrial damage, and neuronal cytotoxicity.</p>
    Fórmula:C12HF23O2
    Pureza:98.42%
    Forma y color:Solid
    Peso molecular:614.1
  • FV-100

    CAS:
    FV-100 (Valnivudine HCl), API for CF-1743, is a potent, oral anti-vaxx-zoster drug with low in vivo toxicity.
    Fórmula:C27H36ClN3O6
    Pureza:98.52%
    Forma y color:Solid
    Peso molecular:534.04
  • Maritimetin

    CAS:
    <p>Maritimein, an aurone from Coreopsis tinctoria, has potent antioxidant activity (IC50: 4.12 μM) and is used in cardiovascular research.</p>
    Fórmula:C15H10O6
    Forma y color:Solid
    Peso molecular:286.24
  • NH2-UAMC1110 TFA

    CAS:
    <p>NH2-UAMC1110 TFA, a derivative of the fibroblast activation protein (FAP) inhibitor UAMC1110, serves as a precursor in the formation of FAPI-QS, a chelating</p>
    Fórmula:C23H24F5N5O5
    Pureza:99.02%
    Forma y color:Solid
    Peso molecular:545.46
  • TMV-IN-6


    <p>TMV-IN-6 (Compound 4g) serves as a novel antiviral and fungicidal agent that impedes tobacco mosaic virus (TMV) assembly, functioning by attachment to TMV coat</p>
    Fórmula:C29H27N3OS
    Forma y color:Solid
    Peso molecular:465.61
  • 4-methyl-6-phenyl-2H-pyranone

    CAS:
    <p>4-methyl-6-phenyl-2H-pyranone from Scutellaria boosts mitochondria, shields astrocytes from peroxide.</p>
    Fórmula:C12H10O2
    Pureza:>99.99%
    Forma y color:Solid
    Peso molecular:186.21
  • StemRegenin 1 Hydrochloride

    CAS:
    <p>StemRegenin 1 Hydrochloride is an AhR antagonist (IC₅₀ = 127 nM) that inhibits RANKL-induced osteoclast generation and differentiation.</p>
    Fórmula:C24H24ClN5OS
    Pureza:99.94%
    Forma y color:Solid
    Peso molecular:466
  • MyD88-IN-2


    <p>MyD88-IN-2 (compound A5S) is a MyD88 inhibitor with a Kd value of 15 μM. It demonstrates protective effects in mouse models of acute lung injury induced by LPS and sepsis.</p>
    Fórmula:C22H26BrN3O2
    Forma y color:Solid
    Peso molecular:444.365
  • Anti-inflammatory agent 78


    <p>Anti-inflammatory agent 78 (compound L-37) is a potent anti-inflammatory agent. It effectively inhibits PGE2, PGE1, COX-2, and COX-1. Additionally, Anti-inflammatory agent 78 suppresses the release of NO in LPS-stimulated RAW 264.7 cell lines.</p>
    Fórmula:C19H14ClNO4
    Peso molecular:355.06114
  • Damnacanthol


    <p>Damnacanthol is a useful organic compound for research related to life sciences and the catalog number is T131609.</p>
    Fórmula:C16H12O5
    Forma y color:Solid
    Peso molecular:284.267
  • β-Amyrin acetate

    CAS:
    Beta-Amyrin acetate: HMGCR & sEH inhibitor (IC50 3.4 μM), anti-inflammatory, antifungal, antioxidant, anti-hyperlipidemic.
    Fórmula:C32H52O2
    Pureza:99.87%
    Forma y color:Solid
    Peso molecular:468.75
  • Dazostinag

    CAS:
    <p>Dazostinag (TAK-676) is a STING agonist with anti-cancer properties, used in making ADCs.</p>
    Fórmula:C21H22F2N8O10P2S2
    Forma y color:Solid
    Peso molecular:710.52
  • GB2095


    <p>GB2095 is an orally effective and selective inhibitor of galectin-3, exhibiting binding affinities (Kd) of 36 nM for human galectin-3 and 0.35 μM for mouse galectin-3. In mouse models, GB2095 demonstrates antitumor activity.</p>
    Fórmula:C20H17BrClF2N3O4S
    Forma y color:Solid
    Peso molecular:548.785
  • 2-Hydroxybenzylamine

    CAS:
    <p>2-Hydroxybenzylamine captures IsoLGs, prevents early atrial fibrillation recurrence post-ablation.</p>
    Fórmula:C7H9NO
    Pureza:95.93%
    Forma y color:Coa
    Peso molecular:123.15
  • BMS-986235

    CAS:
    <p>BMS-986235 (LAR-1219), an oral FPR2 agonist, EC50: 0.41 nM (hFPR2), 3.4 nM (mFPR2), may prevent heart failure.</p>
    Fórmula:C18H17F2N3O3
    Pureza:99.85%
    Forma y color:Solid
    Peso molecular:361.34
  • Efmarodocokin alfa

    CAS:
    <p>Efmarodocokin alfa, IL-22/IgG4 fusion protein, activates IL-22 pathways, researched for severe COVID-19 pneumonia.</p>
    Forma y color:Liquid
  • Efineptakin alfa

    CAS:
    <p>Efineptakin alfa (NT-17), a recombinant IL-7, boosts CD4+ and CD8+ cell growth and is used in glioblastoma studies.</p>
    Forma y color:Liquid
  • Biotin-labeled ODN 1826 sodium


    <p>Biotin-labeled ODN 1826 (sodium), a class B CpG oligodeoxynucleotide (ODN), serves as a TLR9 agonist and facilitates assessment of CpG ODN cellular uptake and</p>
    Forma y color:Odour Solid
  • D-NAME (hydrochloride)

    CAS:
    <p>D-NAME, a less active NO synthase inhibitor enantiomer, has mild cardiovascular effects in rats; inactive in mouse nociception.</p>
    Fórmula:C7H16ClN5O4
    Forma y color:Solid
    Peso molecular:269.69
  • MAPK-IN-4


    <p>MAPK-IN-4 (Compound c1) is an orally active anti-inflammatory agent that inhibits the expression and release of pro-inflammatory cytokines IL-6 and TNF-α induced by LPS. It interacts with IRAK4 to exert its anti-inflammatory effects by inhibiting the MAPK pathway.</p>
    Forma y color:Odour Solid
  • PROTAC IRAK4 degrader-11


    PROTACIRAK4 degrader-11 (compound 15) is a PROTAC molecule utilizing a Cereblon ligand, achieving a maximal IRAK4 degradation rate of 96.25% in HEK293 cells, with a DC50 value of 2.29 nM.
    Fórmula:C41H41F3N8O6
    Peso molecular:798.31012
  • Dithianon

    CAS:
    Dithianon: broad-spectrum anthraquinone fungicide; sticks to leaves/fruits; controls various fungi in some produce.
    Fórmula:C14H4N2O2S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:296.32
  • CP-447697

    CAS:
    CP-447697, a lipophilic C5a receptor antagonist, exhibits an IC50 of 31 nM. It is utilized in inflammation research.
    Fórmula:C29H26ClF2N3O2S
    Pureza:99.90%
    Forma y color:Soild
    Peso molecular:554.05
  • M133 peptide


    <p>The M133 peptide is a coronavirus-specific CD4 T cell epitope. In mice infected with the neurotropic coronavirus (strain JHM of mouse hepatitis virus), the M133 peptide demonstrates immunodominance. It activates CD4 T cells by forming an MHC/peptide complex through binding with MHC II molecules, which is recognized by specific TCRs.</p>
    Fórmula:C84H130N20O25
    Peso molecular:1818.9516
  • SARS-CoV-2-IN-39

    CAS:
    <p>SARS-CoV-2-IN-39 is a SARS-CoV-2 inhibitor with an EC50 of 1 μM.</p>
    Fórmula:C14H8ClF4NO3
    Pureza:99.86%
    Forma y color:Soild
    Peso molecular:349.66
  • COX-2/NLRP3-IN-1


    <p>COX-2/NLRP3-IN-1 (Compound 6k) is an inhibitor that targets COX-2 and NLRP3, exhibiting an IC50 value of 1.53 μM for COX-2. This compound exerts anti-inflammatory effects by inhibiting the NF-κB/NLRP3 signaling pathway.</p>
    Fórmula:C24H19Cl2N5OS
    Peso molecular:495.06874
  • JH-FK-08


    <p>JH-FK-08 is an inhibitor of the serine/threonine-specific phosphatase enzyme calcineurin (calcium-dependent phosphatase). It demonstrates antifungal activity, effectively inhibiting C. neoformans with a MIC80 of 0.8 µg/mL. Additionally, JH-FK-08 exhibits immunosuppressive properties by inhibiting IL-2 expression with an IC50 of 42.6 nM, and shows anti-infective activity in mouse models.</p>
    Fórmula:C45H73N3O13
    Forma y color:Solid
    Peso molecular:864.073
  • Calcitriol Impurities D

    CAS:
    Calcitriol Impurities D: Vitamin hormone, promotes cell differentiation, has bone activity, inhibits HIV, and aids in treating AIDS/viral infections.
    Fórmula:C28H46O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:430.66
  • GB1908


    <p>GB1908 is a selective oral inhibitor of galectin-1 (galectin-1), with Ki values of 57 nM for human galectin-1 and 72 nM for mouse galectin-1. It demonstrates over 50-fold selectivity for galectin-1 compared to galectin-3. GB1908 can be utilized in lung cancer research.</p>
    Fórmula:C18H18Cl2N4O5S2
    Peso molecular:504.00957
  • dsVACV-70mer sodium


    <p>dsVACV-70mer sodium is a 70 base pair double-stranded oligonucleotide that contains a viral DNA motif derived from vaccinia virus DNA. It effectively induces IFN-β through a STING-dependent mechanism.</p>
  • Antiviral agent 61


    <p>Antiviralagent 61 (compound Z40) serves as an effective antiviral agent with activity against Tomato Spotted Wilt Virus (TSWV), exhibiting an EC50 value of 252 µg/mL. It increases the RNA expression of Ndufb9, COX6B, 7.1.2.2, E, COX5B, Ndufs4, and SDHB, while reducing the expression of Ndufb7, Ndufa5, and G.</p>
    Fórmula:C22H23N5O4S
    Forma y color:Solid
    Peso molecular:453.51
  • Ezeprogind

    CAS:
    <p>Ezeprogind, TLR9 inhibitor for Alzheimer's. Affordable Excellence: Reliable Quality You Can Trust</p>
    Fórmula:C25H44N6
    Pureza:99.28%
    Forma y color:Solid
    Peso molecular:428.66
  • Glutaminase C-IN-2


    <p>Glutaminase C-IN-2 (compound 11), an allosteric inhibitor of glutaminase C (GAC), exhibits potent inhibitory activity with an IC50 of 10.64 nM.</p>
    Fórmula:C24H23N7O2S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:473.55
  • mPGES-1/5-LOX-IN-1


    mPGES-1/5-LOX-IN-1 (compound 3j) is a potent, orally active dual inhibitor of mPGES-1 and 5-LOX, with IC50 values of 0.92 and 1.89 µM, respectively. Additionally, mPGES-1/5-LOX-IN-1 exhibits anti-inflammatory properties.
    Fórmula:C20H22N4O6S
    Peso molecular:446.12601
  • TBK1/IKKε-IN-6

    CAS:
    <p>TBK1/IKKε-IN-6 (example 110) is a potent inhibitor of TBK1 and IKKε, with IC50 values of less than 100 nM for both enzymes.</p>
    Fórmula:C31H36F2N8O4
    Forma y color:Solid
    Peso molecular:622.678
  • UNC9036


    <p>UNC9036 is a PROTAC degrader of STING, with a DC50 value of 227 nM. The degradation of STING mediated by UNC9036 is dependent on the proteasomal VHL pathway.</p>
    Fórmula:C73H95N17O11S
    Peso molecular:1417.71177
  • Antibiofilm agent-8


    <p>Antibiofilm agent-8 (compound Ru2) boosts antibacterial activity under visible light (400-700 nm, 10 J cm-2). It induces oxidative stress by promoting NADH oxidation and reactive oxygen species (ROS) generation, which disrupts the bacterial cell wall.</p>
    Fórmula:C35H23ClF6N7PRu
    Peso molecular:823.03887
  • 6Lac[6]Met

    CAS:
    <p>6Lac[6]Met is a galectin-4 inhibitor with an IC50 value of 5 μM [1].</p>
    Fórmula:C126H180N12O66S6
    Forma y color:Solid
    Peso molecular:3111.21
  • PROTAC IRAK4 degrader-5

    CAS:
    <p>PROTAC IRAK4 degrader-5 is a Cereblon-based IRAK4 degrader.</p>
    Fórmula:C41H40F3N11O9
    Forma y color:Solid
    Peso molecular:887.834
  • HSV-60mer sodium


    <p>HSV-60mer sodium is a 60 bp double-stranded oligonucleotide that includes viral DNA motifs from the herpes simplex virus 1 (HSV-1) genome. Transfection of HSV-60mer effectively induces IFN-β in a manner dependent on STING, TBK1, and IFN regulatory factor 3 (IRF3).</p>
  • CAY10512

    CAS:
    <p>CAY10512, a resveratrol analog, is 100x more potent, inhibiting NF-κB with an IC50 of 0.15 μM versus resveratrol's 20 μM.</p>
    Fórmula:C15H13FO
    Forma y color:Solid
    Peso molecular:228.266
  • Mipeginterferon alfa-2b

    CAS:
    <p>Mipeginterferon alfa-2b, an IFNA2b analogue, has 5 modified amino groups out of 11 and weighs 40 kDa.</p>
    Forma y color:Liquid
  • MC-ND-18


    <p>MC-ND-18 is an ATTEC degrader that facilitates the degradation of NLRP3 via autophagy, exhibiting a DC50 of 125.5 nM in THP-1 cells. It is composed of an NLRP3 ligand, a linker, and an LC3 ligand.</p>
    Fórmula:C42H42Br2IN3O9S
    Peso molecular:1049.00532
  • NOD1 antagonist-2


    <p>NOD1antagonist-2 (compound 66) is an orally active and selective inhibitor that can suppress NOD1 in both humans and mice. It effectively blocks the NOD1-induced NF-κB and MAPK pathways.</p>
    Fórmula:C21H13Cl2F2N3O5S2
    Forma y color:Solid
    Peso molecular:560.378
  • NLRP3-IN-55


    NLRP3-IN-55 (Compound 19) is an effective inhibitor of NLRP3, exhibiting an inhibitory concentration (IC50) of 0.34 μM. It targets the NLRP3 protein directly with a dissociation constant (KD) of 0.45 μM, effectively blocking the assembly and activation of the NLRP3 inflammasome. This action results in anti-inflammatory effects and inhibits cell pyroptosis.
    Fórmula:C32H30ClFN2O4
    Forma y color:Solid
    Peso molecular:561.04
  • STING agonist-31

    CAS:
    <p>STING agonist-31, a potent STING agonist, exhibits EC50 values of 0.24 μM and 39.51 μM for human STING (h-STING) and murine STING (m-STING), respectively,</p>
    Fórmula:C43H51N15O6
    Forma y color:Solid
    Peso molecular:873.96
  • Benz-AP

    CAS:
    <p>Benz-AP: potent photosensitizer, creates singlet oxygen, more toxic in low hCES2 cancer cells, generates ROS via TPE to kill tumors.</p>
    Fórmula:C20H13NO2
    Forma y color:Solid
    Peso molecular:299.32
  • OVA Peptide(257-264) acetate salt


    <p>OVA Peptide(257-264) acetate salt is a Class I (Kb)-restricted epitope of OVA. This octamer peptide is presented by Class I MHC molecule H-2Kb derived from ovalbumin.</p>
    Fórmula:C47H78N10O15
    Peso molecular:1022.56481
  • (-)-10,11-Dihydroxyfarnesol

    CAS:
    <p>(-)-10,11-Dihydroxyfarnesol, from Cryptomarasmius aucubae, inhibits NO production.</p>
    Fórmula:C15H28O3
    Forma y color:Solid
    Peso molecular:256.38
  • Suc-Tyr-Val-Ala-Asp-pNA

    CAS:
    <p>Suc-YVAD-pNA, a chromogenic caspase-1 substrate.</p>
    Fórmula:C31H38N6O12
    Forma y color:Solid
    Peso molecular:686.675
  • ZM640


    ZM640 is an NLRP3 inhibitor that promotes IL-1β release mediated by NLRP3 inflammasome activation in THP-1 cells. It demonstrates low cytotoxicity.
    Fórmula:C28H36F3NO8S
    Peso molecular:603.21137
  • WAY-605471

    CAS:
    WAY-605471 is a AHR antagonist with IC50 of 0.5 - 1 μM.
    Fórmula:C14H15NO3S2
    Pureza:99.62%
    Forma y color:Solid
    Peso molecular:309.4
  • Siegesbeckialide I


    <p>Siegesbeckialide I effectively suppresses LPS-induced NO production in RAW264.7 murine macrophages by directly interacting with IKKα/β.</p>
    Fórmula:C20H28O6
    Forma y color:Solid
    Peso molecular:364.43
  • R-HP210


    <p>R-HP210 blocks LPS-triggered IL-1β, IL-6, COX-2 gene transcription and has a 3.80 μM IC50 for NF-κB inhibition without activating GCs.</p>
    Fórmula:C22H19N3O2S2
    Forma y color:Solid
    Peso molecular:421.54
  • UNC8900


    UNC8900 is a VHL-recruiting STINGPROTAC degrader with a DC50 of 0.924 μM. It is applicable for the study of bacterial and viral infections.
    Fórmula:C75H99N17O15S
    Peso molecular:1509.72273
  • ODN D-SL03

    CAS:
    <p>ODN D-SL03, a C class CpG oligonucleotide, stimulates PBMCs, activating B cells, NK cells &amp; monocytes, and can inhibit tumor growth.</p>
    Forma y color:Solid
    Peso molecular:9345
  • STING modulator-5

    CAS:
    <p>STING modulator-5: pIC50 9.5, antagonizes PBMC (pIC50 8.1), THP-1 cell antagonist, for immunology research.</p>
    Fórmula:C43H45F4N11O5
    Forma y color:Solid
    Peso molecular:871.88
  • EC1169

    CAS:
    <p>EC1169 is a targeted PSMA ligand that acts to inhibit the proliferation of cells expressing PSMA.</p>
    Fórmula:C78H112N14O28S3
    Forma y color:Solid
    Peso molecular:1790.00
  • Chitoheptaose heptahydrochloride

    CAS:
    <p>Chitoheptaose heptahydrochloride, a chitosan derivative, enhances wheat growth and photosynthesis, with health-protective traits.</p>
    Fórmula:C42H80ClN7O29
    Forma y color:Solid
    Peso molecular:1182.57
  • ROS-ERS inducer 1


    <p>Type II ICD agent, ROS-ERS inducer 1, is a Pt(II)-NHC from 4,5-diarylimidazole, boosting ER stress, ROS, and DAMPs in HCC, outperforming Cisplatin.</p>
    Fórmula:C24H23F2I2N3Pt
    Forma y color:Solid
    Peso molecular:840.35
  • cGAS-IN-3


    <p>cGAS-IN-3 (compound 30d-S) is an orally active inhibitor of cyclic GMP-AMP synthase (cGAS) that exhibits excellent plasma exposure and low clearance rate. It demonstrates anti-inflammatory properties, significantly reducing pulmonary inflammation in rats.</p>
    Fórmula:C21H20Cl2F2N4O2
    Peso molecular:468.09314
  • Porphyra 334

    CAS:
    <p>Porphyra 334 is a mycosporine-like amino acid.</p>
    Fórmula:C14H22N2O8
    Forma y color:Solid
    Peso molecular:346.336
  • Human Immunoglobulin M


    <p>Human Immunoglobulin M (IgM) is an antibody secreted by the adaptive immune system in response to foreign antigens. It is a primary type of immunoglobulin released into circulation during the early stages of the primary antibody response. Human Immunoglobulin M forms a pentamer comprising five IgG equivalents, with 10 Fab fragments, allowing for 10 antigen binding sites. Additionally, Human Immunoglobulin M acts as a complement (complement) activator.</p>
    Forma y color:Odour Solid
  • Englumafusp alfa


    <p>Englumafusp alfa (CD19-4-1BBL; RO7227166) is a fusion protein combining a CD19-specific antibody domain with trimerized extracellular domains of human 4-1BBL,</p>
    Forma y color:Odour Liquid
  • Mitoquinol

    CAS:
    Mitoquinol is a mitochondria-targeted antioxidant used in the study of cardiovascular disease by modulating the mitochondrial antioxidant defense system.
    Fórmula:C38H49O7PS
    Pureza:98%
    Forma y color:Solid
    Peso molecular:680.83
  • (±)-Phrymarolin II

    CAS:
    <p>(±)-Phrymarolin II is a promising class of inhibitors that targets the tobacco mosaic virus, representing a novel approach in plant virus suppression.</p>
    Fórmula:C23H22O10
    Forma y color:Solid
    Peso molecular:458.419
  • Biotin-labeled ODN 1668 sodium


    <p>Biotin-labeled ODN 1668 (sodium), a class B CpG oligodeoxynucleotide (ODN) and TLR9 agonist, facilitates the assessment of cellular uptake and localization of</p>
    Forma y color:Odour Solid
  • (R)-(-)-Ibuprofen

    CAS:
    (R)-(-)-Ibuprofen ((R)-Ibuprofen) is the R enantiomer of Ibuprofen and inhibits NF-κB activation.
    Fórmula:C13H18O2
    Pureza:99.86%
    Forma y color:Solid
    Peso molecular:206.28