Inmunología e inflamación
Los inhibidores de inmunología e inflamación son compuestos que modulan la respuesta inmunitaria y los procesos inflamatorios. Estos inhibidores son cruciales para estudiar los mecanismos de regulación inmunitaria, la autoinmunidad y la inflamación crónica, así como para desarrollar tratamientos para enfermedades inflamatorias, alergias y trastornos relacionados con el sistema inmunológico. Al dirigirse a vías clave en el sistema inmunológico, estos inhibidores pueden ayudar a reducir las respuestas inmunitarias excesivas o inadecuadas. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad para apoyar su investigación en inmunología, inflamación y desarrollo terapéutico.
Subcategorías de "Inmunología e inflamación"
- CCR(136 productos)
- CXCR(149 productos)
- Pared celular(5 productos)
- Receptor de IL(112 productos)
- IκB / IKK(59 productos)
- LTR(3 productos)
- MALT(23 productos)
- MRP(6 productos)
- NADPH-oxidasa(1 productos)
- NF-κB(443 productos)
- NOD(18 productos)
- NOS(62 productos)
- Nrf2(78 productos)
- PGE sintasa(31 productos)
- ROS(69 productos)
- TGF-beta / Smad(58 productos)
- TLR(66 productos)
- Tiorredoxina(12 productos)
- gp120 / CD4(4 productos)
Mostrar 11 subcategorías más
Se han encontrado 3055 productos de "Inmunología e inflamación"
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POT-4 acetate
<p>POT-4 acetate inhibits Complement C3 activation. POT-4 acetate can be used for studies about age-related macular degeneration.</p>Fórmula:C74H106N22O20S2Pureza:98%Forma y color:SolidPeso molecular:1687.9TBK1/IKKε-IN-6
CAS:<p>TBK1/IKKε-IN-6 (example 110) is a potent inhibitor of TBK1 and IKKε, with IC50 values of less than 100 nM for both enzymes.</p>Fórmula:C31H36F2N8O4Forma y color:SolidPeso molecular:622.678MTvkPABC-P5 TFA
<p>MTvkPABC-P5d TFA, a TLR7 agonist, functions as an immune stimulant. It is applicable in the synthesis of immune-stimulating antibody conjugates (ISAC).</p>Forma y color:Odour Solidα-Guanidinoglutaric Acid
CAS:<p>α-Guanidinoglutaric Acid is found in cobalt-induced epileptogenic focus tissue in the cerebral cortex of cats.</p>Fórmula:C6H11N3O4Pureza:99.73%Forma y color:SolidPeso molecular:189.17Maresin 2
CAS:<p>Maresin 2 (3R,14S-diHDHA) is a specialized pro-ablative lipid mediator with anti-inflammatory and analgesic activity that promotes mucosal repair.</p>Fórmula:C22H32O4Forma y color:SolidPeso molecular:360.49QX-005N
QX 005N is a humanized monoclonal anti-CD124/IL4R/IL-4Rα antibody. It is applicable in research related to asthma.Forma y color:Odour LiquidRedaporfin
CAS:<p>Redaporfin (F-2BMet, LUZ-11) is a PDT cancer photosensitizer; 83% of mice had tumor regression with 1.5 mg/kg and 74 J/cm² light.</p>Fórmula:C48H38F8N8O8S4Forma y color:SolidPeso molecular:1135.11NLRP3-IN-73
<p>NLRP3-IN-73 (W16) is an orally bioavailable inhibitor that disrupts the assembly of the NLRP3 inflammasome, exhibiting an IC50 value of 0.18 μM for the NLRP3/IL-1β pathway.</p>Forma y color:Odour SolidhSTING activator-1
<p>hSTING activator-1 (Compound 68) is a STING agonist capable of effectively activating various human STING variants (R232, H232, HAQ), with EC50 values of 56 nM, 89 nM, and 51 nM, respectively. This compound activates the type I interferon pathway by directly binding to the STING protein and stabilizing its conformation, which leads to downstream IRF3 phosphorylation and cytokine release. hSTING activator-1 also demonstrates potential in cancer research by inhibiting fibrosarcoma tumor growth.</p>Forma y color:Odour SolidBiotin-labeled ODN TTAGGG sodium
<p>Biotin-labeled ODN TTAGGG (sodium) is an inhibitory oligonucleotide (ODN) that functions as an antagonist to TLR9, AIM2, and cGAS.</p>Forma y color:Odour SolidGHN105
<p>GHN105 is an orally active STING inhibitor that suppresses STING-dependent IFN-β secretion in THP-1 human monocytes with an IC50 of 4.4 μM. In mice, GHN105 reduces serum levels of IFN-β, IL-6, and CXCL10, and alleviates colitis in a DSS-induced acute colitis mouse model. Additionally, GHN105 demonstrates favorable pharmacokinetic properties in mice, with an oral bioavailability of 43% and a half-life of 1.1 hours.</p>Fórmula:C41H56N2O14Forma y color:SolidPeso molecular:800.89JPE-1375
CAS:<p>JPE-1375: a C5aR1 antagonist, blocks leukocyte mobilization (EC50=6.9 µM), lowers TNF in mice (EC50=4.5 µM), useful for autoimmune/inflammation research.</p>Fórmula:C49H63FN10O9Forma y color:SolidPeso molecular:955.08Prifelone
CAS:<p>Prifelone (R 830) is a non-steroidal anti-inflammatory compound with antioxidant activity.</p>Fórmula:C19H24O2SPureza:99.8%Forma y color:SolidPeso molecular:316.46(±)19(20)-EDP Ethanolamide
CAS:<p>(±)19(20)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 108 and 280 nM for CB1 and CB2, respectively).</p>Fórmula:C24H37NO3Forma y color:SolidPeso molecular:387.564MC4762
<p>MC4762 is an inhibitor of NOX2 and MAOB, with IC50 values of 0.155 μM and 0.182 μM, respectively. It exhibits anti-inflammatory properties by suppressing the production of ROS and downregulating the expression of pro-inflammatory cytokines such as iNOS, IL-1β, and IL-6.</p>Forma y color:Odour SolidRH-EDA
<p>RH-EDA, a rhodamine-based turn-on fluorescent probe, detects hydroxyl radicals ([OH]) in living systems.</p>Fórmula:C28H25N3O4Forma y color:SolidPeso molecular:467.523D-Monophosphoryl Lipid (12,16) free acid
CAS:3D-Monophosphoryl Lipid (12,16) (3D-MPL (12,16)) free acid is a TLR agonist that serves as a vaccine adjuvant to boost the immunogenicity of vaccines.Fórmula:C96H181N2O21PForma y color:SolidPeso molecular:1730.44MitoP
CAS:<p>MitoP forms from H2O2 and MitoB, indicating mitochondria's H2O2 levels when measured by LC-MS/MS.</p>Fórmula:C25H22BrOPForma y color:SolidPeso molecular:449.32Gliotoxin
CAS:<p>Gliotoxin, a mycotoxin, inhibits Wnt pathway, causing apoptosis in mutated colorectal cancer cells and blocks NF-κB by preserving IκB.</p>Fórmula:C13H14N2O4S2Pureza:98%Forma y color:SolidPeso molecular:326.39PSB-12379 ditriethylamine salt
PSB-12379 ditriethylamine salt, a nucleotide analogue, is a potent Ecto-5'-Nucleotidase (CD73) inhibitor with Kis of 9.03 nM (rat) and 2.21 nM (human).Fórmula:C30H53N7O9P2Pureza:99.44% - 99.97%Forma y color:SolidPeso molecular:717.73CU-115
CAS:<p>CU-115 is a selective and potent TLR8 antagonist with IC50 of 1.04 µM and =>50 µM for TLR8 and TLR7, respectively.</p>Fórmula:C21H11F7INO2Pureza:99.96%Forma y color:SolidPeso molecular:569.21Vemircopan
CAS:<p>Vemircopan is a complement factor D inhibitor.</p>Fórmula:C29H28BrN7O3Forma y color:SolidPeso molecular:602.493Perfluorohexane
CAS:<p>Perfluorohexane (AF-0150) is a perfluorocarbon (PFC)-based microbubble formulation for ultrasound contrast and is developmentally toxic.</p>Fórmula:C6F14Pureza:98%Forma y color:Colourless LiquidPeso molecular:338.04Dazostinag
CAS:<p>Dazostinag (TAK-676) is a STING agonist with anti-cancer properties, used in making ADCs.</p>Fórmula:C21H22F2N8O10P2S2Forma y color:SolidPeso molecular:710.52Amphimedine
CAS:<p>Amphimedine is a Pyridoacridine Marine Alkaloid.</p>Fórmula:C19H11N3O2Forma y color:SolidPeso molecular:313.31Mesalamine impurity P
CAS:<p>Mesalamine impurity P, a 5-Aminosalicylic acid derivative, is a PPARγ agonist, inhibiting PAK1 and NF-κB.</p>Fórmula:C13H11NO6SForma y color:SolidPeso molecular:309.30Dibenzothiophene
CAS:<p>Dibenzothiophene, a sulfur PAH in petroleum, has 3 rings and keratolytic properties.</p>Fórmula:C12H8SPureza:99.82%Forma y color:Yellow To Green SolidPeso molecular:184.26NLRP3-IN-50
NLRP3-IN-50 (compound SN3-1) is a potential inhibitor of NLRP3, offering therapeutic promise for inflammatory diseases.Fórmula:C23H22Cl2N2O4S2Forma y color:SolidPeso molecular:525.47RS 09 TFA
<p>RS 09 TFA is a TLR4 agonist and LPS peptide analogue, promotes NF-κB nuclear translocation, induces inflammatory cytokine secretion in RAW264.7 macrophages.</p>Fórmula:C33H50F3N9O11Pureza:99.78%Forma y color:SolidPeso molecular:805.8PSMA-ALB-56
CAS:<p>PSMA-ALB-56: radioactive, PSMA-targeted ligand, antitumor, combines glutamic urea, DOTA, albumin, with iodophenyl or tolyl fragments.</p>Fórmula:C66H95N11O18Forma y color:SolidPeso molecular:1330.52Mifamurtide TFA
<p>Mifamurtide TFA: muramyl dipeptide analog, boosts immunity, activates macrophages/monocytes, potential osteosarcoma research.</p>Fórmula:C61H110F3N6O21PForma y color:SolidPeso molecular:1351.52MS7829
MS7829 is a first-class DUBTAC targeting cGAS, a critical component in the cGAS-STING pathway.Forma y color:Odour SolidLY-402913
CAS:<p>LY-402913 is a selective multidrug resistance protein (MRP1) inhibitor.</p>Fórmula:C28H24ClN3O6Pureza:99.73%Forma y color:SolidPeso molecular:533.964-hydroperoxy 2-Nonenal
CAS:<p>4-HNE, a marker of oxidative stress, arises from oxidized ω-6 fats like linoleic acid and shows cytotoxic and genotoxic effects.</p>Fórmula:C9H16O3Forma y color:SolidPeso molecular:172.224Guaiacol-d3
CAS:Guaiacol-d3 is a deuterated form of Guaiacol, which is a phenolic compound known for its ability to inhibit COX-2 expression and NF-κB activation in response to LPS stimulation, exhibiting anti-inflammatory properties.Fórmula:C7H8O2Forma y color:SolidPeso molecular:127.16Bermoprofen
CAS:<p>Bermoprofen (AD-1590) is an anti-inflammatory compound with anti-inflammatory and analgesic activity used in the study of gastric ulcers.</p>Fórmula:C18H16O4Pureza:98.72% - 99.28%Forma y color:SolidPeso molecular:296.32BMS-986148
<p>BMS-986148 is a CHO-expressed humanized antibody-drug coupling targeting mesothelin-expressing cells for cytotoxic load delivery.</p>Pureza:98.1% (SDS-PAGE); 99% (SEC-HPLC) - 98.1% (SDS-PAGE); 99% (SEC-HPLC)Forma y color:Odour LiquidInflexuside B
CAS:<p>Inflexuside B, an abietane diterpenoid derived from the aerial parts of Isodon inflexus, effectively inhibits lipopolysaccharide (LPS)-activated NO Synthase in</p>Fórmula:C35H48O11Forma y color:SolidPeso molecular:644.75Flunixin
CAS:<p>Flunixin is a nonsteroidal anti-inflammatory drug (NSAID), antipyretic, and analgesic used in pigs, horses, and cattle.</p>Fórmula:C14H11F3N2O2Forma y color:SolidPeso molecular:296.24NOD2 agonist 2
NOD2 agonist 2 (compound 23) enhances antigen presentation in murine bone marrow-derived dendritic cells (BMDCs), highlighting its potential as a vaccine adjuvant.Fórmula:C46H65N3O10Forma y color:SolidPeso molecular:820.024-Methylamino antipyrine hydrochloride
CAS:<p>4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole.</p>Fórmula:C12H16ClN3OPureza:98%Forma y color:SolidPeso molecular:253.73PSMA-D5
CAS:<p>PSMA-D5 exhibits a binding affinity for PSMA with a Ki of 0.21 nM and becomes useful for PSMA tracing following radiolabeling. When marked with [68Ga], PSMA-D5 contains a DOTA chelator, facilitating the convenient labeling with therapeutic radionuclides such as 177Lu and 225Ac. Additionally, [68Ga]-labeled PSMA-D5 demonstrates exceptional pharmacokinetic properties and significant tumor uptake in 22Rv1 tumors. This compound can be employed in the synthesis and research of radiolabeled conjugates (RDC).</p>Fórmula:C57H80N12O24Forma y color:SolidPeso molecular:1317.31Biotin-labeled Agatolimod sodium
<p>Biotin-labeled Agatolimod (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of cellular uptake and localization of</p>Forma y color:Odour SolidSTING-IN-13
<p>STING-IN-13 is a selective STING inhibitor that effectively suppresses downstream signaling of the STING pathway and STING-mediated inflammation. It exhibits low toxicity and is suitable for research related to STING-associated inflammatory and autoimmune diseases.</p>Forma y color:Odour SolidAntitumor agent-188
<p>Antitumor agent-188 (compound C6) exhibits α-glucosidase inhibitory activity and anticancer properties. It induces excessive ROS production, thereby triggering oxidative stress.</p>Fórmula:C25H44FN3O7Forma y color:SolidPeso molecular:517.632'2'-cGAMP (sodium salt)
CAS:<p>2'2'-cGAMP, a synthetic CDN, binds STING in the immune response, inducing IFN-β; binds weaker than 2'3'-cGAMP but stronger than other CDNs.</p>Fórmula:C20H24N10O13P2Forma y color:SolidPeso molecular:674.417IMGN-779
<p>IMGN-779 (Anti-CD33 Antibody) is a humanized antibody targeting CD33 with antileukemic activity, which can be used to study leukemia.</p>Pureza:>95%Forma y color:Odour LiquidDecylubiquinone
CAS:<p>Decylubiquinone (DUb) is a coenzyme Q10 analog with anticancer activity, inhibiting the growth and metastasis of breast cancer.</p>Fórmula:C19H30O4Pureza:99.32% - 99.92%Forma y color:SolidPeso molecular:322.444'-hydroxy Flurbiprofen
CAS:4'-hydroxy Flurbiprofen can be used in related research in the field of life sciences. Its product number is T35722 and CAS number is 52807-12-2.Fórmula:C15H13FO3Forma y color:SolidPeso molecular:260.264CD19 CAR mRNA
<p>CD19 CAR mRNA expresses a protein for use in CAR-CD19 T cell therapy, targeting B cell antigen for cancer treatment.</p>Forma y color:SolidNG-Hydroxy-L-arginine acetate
CAS:NG-Hydroxy-L-arginine acetate (NOHA acetate) acts as a crucial physiological inhibitor of arginase, playing a vital role in the conversion of arginine to nitric oxide and citrulline via nitric oxide synthase.Fórmula:C6H14N4O3xC2H4O2Forma y color:SolidPeso molecular:190.20（free base）(Rac)-γ-Tocopherol
CAS:<p>(Rac)-γ-Tocopherol (DMPBQ) is an isoform of Vitamin E that undergoes conversion to γ-Tocopherol through the action of tocopherol cyclase.</p>Fórmula:C28H48O2Forma y color:SolidPeso molecular:416.68TSR-033
CAS:<p>TSR-033 is a human IgG4 antibody with high affinity for LAG-3 (lymphocyte activation gene-3), a co-receptor linked to diminished T cell activity, frequently co-</p>Forma y color:LiquidAnti-inflammatory agent 93
<p>Compound 2g (Anti-inflammatory agent 93) is an active compound that exhibits analgesic activity.</p>Fórmula:C27H17Cl2N3O2Forma y color:SolidPeso molecular:486.35OVA Peptide(257-264)
CAS:<p>OVA Peptide(257-264) is an ovalbumin octamer Peptide expressed by class I MHC molecule h-2kb.</p>Fórmula:C45H74N10O13Pureza:99.53%Forma y color:SolidPeso molecular:963.132-Iminobiotin
CAS:2-Iminobiotin inhibits iNOS/nNOS; Ki: 21.8 μM (mouse iNOS), 37.5 μM (rat nNOS).Fórmula:C10H17N3O2SPureza:98%Forma y color:SolidPeso molecular:243.33Antifungal agent 123
<p>Antifungalagent 123 (Compound 4b) demonstrates strong affinity for the oxidoreductase of Staphylococcus aureus or membrane proteins of Candida albicans, exhibiting both antibacterial and antifungal properties. Additionally, it is capable of scavenging free radicals, showcasing antioxidant effects. Antifungalagent 123 also inhibits the TLR signaling pathway and possesses anti-inflammatory activity.</p>Fórmula:C21H20N4O3Forma y color:SolidPeso molecular:376.409Multinoside A
CAS:Multinoside A is a useful organic compound for research related to life sciences. The catalog number is T124593 and the CAS number is 59262-54-3.Fórmula:C27H30O16Forma y color:SolidPeso molecular:610.521Pelgifatamab
CAS:<p>Pelgifatamab (BAY-2315497) is a prostate-specific membrane antigen (PSMA) antibody with potential anticancer activity that can be used to study prostate cancer.</p>Pureza:97.9% (SDS-PAGE); 95.1% (SEC-HPLC) - 97.9% (SDS-PAGE); 95.1% (SEC-HPLC)Forma y color:LiquidCarboxy-PTIO
CAS:<p>Carboxy-PTIO rapidly scavenges NO, forming NO2, key in preventing hypotension and shock in rats.</p>Fórmula:C14H17N2O4Forma y color:SolidPeso molecular:277.3Anti-Human MSLN Antibody (Clone HN1)
<p>Anti-Human MSLN Antibody (Clone HN1) is a humanised monoclonal antibody targeting MSLN (Mesothelin), , blocks the interaction between MSLN and CA125, cancer .</p>Pureza:95%Forma y color:Odour LiquidiNOs-IN-6
<p>iNOs-IN-6 is an anti-inflammatory agent known for inhibiting the expression of NF-κB, iNOS, and MAPK with an IC50 ranging from 0.2 to 0.62 μM. Additionally, it decreases the levels of pro-inflammatory mediators, such as IL-6, TNF-α, and IL-1β, with an IC50 ranging from 0.4 to 0.69 μM.</p>Forma y color:Odour SolidPepinh-MYD
CAS:<p>Pepinh-MYD, a MyD88 inhibitor, incorporates both a domain sequence from MyD88 TIR and a protein transduction sequence to facilitate cell membrane penetration. This compound disrupts MyD88-mediated TLR signaling pathways, effectively inhibiting associated immune responses. Its design is particularly useful for investigating MyD88's function in viral infections.</p>Fórmula:C151H248N50O35S2Forma y color:SolidPeso molecular:3388.03CRX-526
CAS:<p>CRX-526, a TLR4 antagonist, protects against advanced diabetic nephropathy.</p>Fórmula:C69H127N2O19PPureza:98%Forma y color:SolidPeso molecular:1319.72TPNA10168
CAS:<p>Compound Fr13590, with CAS No. 957942-34-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr13590 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C9H9ClO2S2Forma y color:SolidPeso molecular:248.75Dithianon
CAS:Dithianon: broad-spectrum anthraquinone fungicide; sticks to leaves/fruits; controls various fungi in some produce.Fórmula:C14H4N2O2S2Pureza:98%Forma y color:SolidPeso molecular:296.32Vadastuximab
<p>Vadastuximab (Anti-Human CD33 Recombinant Antibody) is a humanized anti-CD33 monoclonal antibody for the study of acute myeloid leukemia (AML).</p>Pureza:98.5% (SDS-PAGE); 97.3% (SEC-HPLC) - 98.5% (SDS-PAGE); 97.3% (SEC-HPLC)Forma y color:LiquidPeso molecular:145.5 kDaSomantadine
CAS:<p>Somantadine has antiviral activities and can be used for research on preventing and treating coronavirus-related diseases.</p>Fórmula:C14H25NPureza:99.9%Forma y color:SolidPeso molecular:207.35QKY-613
CAS:<p>QKY-613 is a prodrug designed to enhance immune surveillance by targeting nucleic acid modification pathways. It selectively facilitates the incorporation of 6mdA (N6-methyl-deoxyadenosine) into viral DNA, boosting the DNA's phase separation potential and subsequently increasing cGAS activation levels to strengthen host immune surveillance. In mouse models of viral infection, QKY-613 significantly reduced mortality in aged mice. This compound holds promise for studying immune surveillance mechanisms based on nucleic acid modifications.</p>Fórmula:C27H31N6O7PForma y color:SolidPeso molecular:582.55Englumafusp alfa
<p>Englumafusp alfa (CD19-4-1BBL; RO7227166) is a fusion protein combining a CD19-specific antibody domain with trimerized extracellular domains of human 4-1BBL,</p>Forma y color:Odour LiquidPirenoxine
CAS:<p>Pirenoxine is an agent with anti-cataractogenesis activity by interacting with calcium ions or selenite which could lead to the formation of lens cataract.</p>Fórmula:C16H8N2O5Forma y color:SolidPeso molecular:308.25IL-6-IN-1
IL-6-IN-1 (Compound 22) inhibits the release of IL-6 with an IC50 of 1.065 μM and demonstrates anti-inflammatory activity in LPS-induced acute lung injury in mice.Fórmula:C16H12N2OSForma y color:SolidPeso molecular:280.34PSMα3
CAS:<p>PSMα3 is a peptide compound that can be utilized to induce tolerance in dendritic cells (DCs) for DC vaccination strategies.</p>Fórmula:C128H192N28O30SForma y color:SolidPeso molecular:2635.17ZL-1102
<p>ZL-1102 is a humanized monoclonal antibody inhibitor targeting interleukin-17A (IL-17A). SCH-900117 is being investigated for its potential use in the treatment of autoimmune diseases such as psoriasis and rheumatoid arthritis.</p>Forma y color:Odour LiquidUNC8900
UNC8900 is a VHL-recruiting STINGPROTAC degrader with a DC50 of 0.924 μM. It is applicable for the study of bacterial and viral infections.Fórmula:C75H99N17O15SPeso molecular:1509.72273Keap1-Nrf2-IN-3
CAS:<p>Keap1-Nrf2-IN-3 is a KEAP1:NRF2 protein protein interaction inhibitor, and with a K d value of 2.5 nM for KEAP1 protein.</p>Fórmula:C31H34N6O3Forma y color:SolidPeso molecular:538.652SN50
CAS:<p>SN50 is a cell-permeable inhibitor of NF-κB nuclear translocation that protects against ventilator-induced acute lung injury in rats.</p>Fórmula:C129H230N36O29SPureza:99.91%Forma y color:SolidPeso molecular:2781.5LL-37 GKE acetate
<p>LL-37 GKE acetate, a peptide and active structural domain of LL-37, inhibits lps-induced vascular nitric oxide production,less toxic,antimicrobial，sepsis.</p>Fórmula:C121H206N38O30Pureza:99.88%Forma y color:SolidPeso molecular:2673.17TLR4-IN-C34-C2-amide-C6-OH
<p>TLR4-IN-C34-C2-amide-C6-OH: a linker with TLR4-IN-C34 that curbs TLR4 and inflammation in mice.</p>Fórmula:C25H42N2O11Forma y color:SolidPeso molecular:546.61Antiviral agent 61
<p>Antiviralagent 61 (compound Z40) serves as an effective antiviral agent with activity against Tomato Spotted Wilt Virus (TSWV), exhibiting an EC50 value of 252 µg/mL. It increases the RNA expression of Ndufb9, COX6B, 7.1.2.2, E, COX5B, Ndufs4, and SDHB, while reducing the expression of Ndufb7, Ndufa5, and G.</p>Fórmula:C22H23N5O4SForma y color:SolidPeso molecular:453.51NLRP3-IN-15
CAS:<p>NLRP3-IN-15: potent, selective NLRP3 inflammasome inhibitor; IC50 0.114 μM for IL-1β; for inflammation research.</p>Fórmula:C22H19NO4Forma y color:SolidPeso molecular:361.39Numidargistat dihydrochloride
<p>Numidargistat dihydrochloride is an ARG1 inhibitor and an immuno-oncology agent that inhibits TGF-β2-induced pre-lens cataract formation.</p>Fórmula:C11H24BCl2N3O5Pureza:99.49%Forma y color:SolidPeso molecular:360.04ABX-IL8
<p>ABX-IL8 is a humanized antibody targeting IL-8, capable of interfering with tube formation in human umbilical vein endothelial cells.</p>Pureza:>95%Forma y color:LiquidPeso molecular:145.5 kDadiABZI STING agonist-1 trihydrochloride
CAS:<p>diABZI STING agonist-1 (trihydrochloride) is stimulator of interferon genes (STING) receptor agonist.</p>Fórmula:C42H54Cl3N13O7Pureza:95.33% - 99.55%Forma y color:SolidPeso molecular:959.32Tri(TLR4-IN-C34-PEG2-amide-PEG1)-amide-C3-COOH
<p>Tri(TLR4-IN-C34-PEG2/PEG1)-amide-C3-COOH is a TLR4 inhibiting linker, reducing inflammation in endotoxemia and enterocolitis mouse models.</p>Fórmula:C78H125N7O42Forma y color:SolidPeso molecular:1832.85Axinelline A
CAS:<p>Axinelline A: COX inhibitor, IC50 of 2.22 μM (COX-2) & 8.89 μM (COX-1), anti-inflammatory.</p>Fórmula:C12H15NO6Forma y color:SolidPeso molecular:269.25β-Interleukin II (44-56)
β-Interleukin II is a peptide with the sequence NH2-ILE-LEU-ASN-GLY-ILE-ASN-ASN-TYR-LYS-ASN-PRO-LYS-LEU-COOH.Fórmula:C68H113N19O19Pureza:98%Forma y color:SolidPeso molecular:1500.74Fentiazac
CAS:<p>Fentiazac (BR-700) is an oral NSAID for pain, inflammation, fever, studied for arthritis and tendonitis.</p>Fórmula:C17H12ClNO2SPureza:99.83%Forma y color:SolidPeso molecular:329.8FITC-labeled ODN 2395 sodium
<p>FITC-labeled ODN 2395 (sodium), a class C oligodeoxynucleotide and TLR9 agonist, facilitates the assessment of CpG ODN cellular uptake and localization through</p>Forma y color:Odour SolidPegaldesleukin
CAS:<p>Pegaldesleukin, a PEG-IL2 conjugate, exhibits antiviral properties, potentially slowing HIV progression, preserving immune function.</p>Forma y color:LiquidSartorypyrone D
CAS:<p>Sartorypyrone D, from N. fischeri, inhibits NFRD (1.7 μM) and NADH oxidase (3 μM), and fights Gram-positive bacteria.</p>Fórmula:C26H38O4Forma y color:SolidPeso molecular:414.586Aβ-IN-6
<p>Aβ-IN-6 is an orally active compound exhibiting anti-inflammatory, antioxidant, and anti-oligomeric activities, with significant implications for Alzheimer's</p>Fórmula:C28H31N3O4Forma y color:SolidPeso molecular:473.56CHBO4
CAS:<p>CHBO4 is an hMAO-B inhibitor that is potent, reversible, competitive and selective.The IC50 value of CHBO4 against hMAO-B in the CHBO assay was 0.031 μM, and</p>Fórmula:C15H10BrFOPureza:98.14%Forma y color:SolidPeso molecular:305.14IL-17-IN-3
<p>IL-17-IN-3 (compound 11) is an IL-17A inhibitor with an IC50 value of 35 nM. In a rat tolerance study, it showed no adverse reactions when administered at doses up to 300 mg/kg/day for four consecutive days.</p>Fórmula:C22H25F6N5O3SForma y color:SolidPeso molecular:553.521IACS-8803 disodium
CAS:<p>IACS-8803 Disodium, a potent cyclic dinucleotide STING agonist, exhibits strong systemic antitumor efficacy [1].</p>Fórmula:C20H21FN10Na2O9P2S2Forma y color:SolidPeso molecular:736.50R-HP210
<p>R-HP210 blocks LPS-triggered IL-1β, IL-6, COX-2 gene transcription and has a 3.80 μM IC50 for NF-κB inhibition without activating GCs.</p>Fórmula:C22H19N3O2S2Forma y color:SolidPeso molecular:421.54CIB-1476
<p>CIB-1476, a caspase-1 inhibitor, effectively reduces joint swelling in mouse models of arthritis and demonstrates lasting anti-inflammatory effects. This compound achieves its benefits by blocking IL-1β production, NF-κB activation, and GSDMD-mediated pyroptosis, all of which are triggered by the NLRP3 inflammasome.</p>Fórmula:C28H28N2O6SForma y color:SolidPeso molecular:520.6Damnacanthol
<p>Damnacanthol is a useful organic compound for research related to life sciences and the catalog number is T131609.</p>Fórmula:C16H12O5Forma y color:SolidPeso molecular:284.267Nrf2 activator 18
<p>Nrf2 activator 18 (Compound 11a) is an orally active activator of the Keap1/Nrf2/HO-1 signaling pathway, promoting Nrf2 nuclear translocation and enhancing antioxidant effects. It inhibits IL-6 release with an IC50 of 4.816 μM. In a mouse model of PM2.5-induced lung injury, Nrf2 activator 18 demonstrates anti-inflammatory activity.</p>Fórmula:C23H24FN3OForma y color:SolidPeso molecular:377.45IACS-8803 diammonium
<p>IACS-8803 diammonium, a potent cyclic dinucleotide STING agonist, demonstrates robust systemic antitumor efficacy [1].</p>Fórmula:C20H29FN12O9P2S2Forma y color:SolidPeso molecular:726.6
