Inmunología e inflamación
Los inhibidores de inmunología e inflamación son compuestos que modulan la respuesta inmunitaria y los procesos inflamatorios. Estos inhibidores son cruciales para estudiar los mecanismos de regulación inmunitaria, la autoinmunidad y la inflamación crónica, así como para desarrollar tratamientos para enfermedades inflamatorias, alergias y trastornos relacionados con el sistema inmunológico. Al dirigirse a vías clave en el sistema inmunológico, estos inhibidores pueden ayudar a reducir las respuestas inmunitarias excesivas o inadecuadas. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad para apoyar su investigación en inmunología, inflamación y desarrollo terapéutico.
Subcategorías de "Inmunología e inflamación"
- CCR(140 productos)
- CXCR(153 productos)
- Pared celular(5 productos)
- Receptor de IL(108 productos)
- IκB / IKK(59 productos)
- LTR(3 productos)
- MALT(24 productos)
- MRP(6 productos)
- NADPH-oxidasa(1 productos)
- NF-κB(445 productos)
- NOD(17 productos)
- NOS(62 productos)
- Nrf2(82 productos)
- PGE sintasa(31 productos)
- ROS(70 productos)
- TGF-beta / Smad(59 productos)
- TLR(74 productos)
- Tiorredoxina(12 productos)
- gp120 / CD4(4 productos)
Mostrar 11 subcategorías más
Se han encontrado 3269 productos de "Inmunología e inflamación"
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CD73-IN-13
CD73-IN-13, a potent CD73 inhibitor, may be developed for tumor-related disease treatment.Fórmula:C13H11F3N4O2Forma y color:SolidPeso molecular:312.25PB01
CAS:<p>PB01 is a DPP-4 inhibitor with an IC50 of 15.66 nM. It effectively suppresses high glucose-induced ROS generation and mitochondrial superoxide production while significantly reducing the cellular expression of DPP-4. Additionally, PB01 notably lowers blood glucose levels in diabetic mice. It demonstrates excellent safety, exhibiting almost no cytotoxicity at a concentration of 100 μM. PB01 holds promise for research in the diabetes field.</p>Fórmula:C18H21N5O3Forma y color:SolidPeso molecular:355.391STING agonist-43
CAS:STINGagonist-43 (Compound 67) is a selective STING agonist with an EC50 of 20.53 μM. It selectively enhances the cGAMP-dependent STING pathway activation by modulating STING oligomerization. STINGagonist-43 demonstrates antitumor activity in a B16.F10 mouse melanoma model and can be utilized in cancer immunotherapy research.Fórmula:C21H23NO4Forma y color:SolidPeso molecular:353.41NLRP3-IN-70
CAS:<p>NLRP3-IN-70 (Compound 5m) is an inhibitor of the NLRP3 inflammasome with low oral bioavailability. It binds directly to the NACHT domain of the NLRP3 protein, thereby blocking its interaction with ASC, which inhibits ASC oligomerization and the assembly of the NLRP3 inflammasome. NLRP3-IN-70 is applicable in studies on sepsis and non-alcoholic steatohepatitis.</p>Fórmula:C23H23NO5Forma y color:SolidPeso molecular:393.432GTCpFE
CAS:GTCpFE, a compound synthesized from Dimethyl fumarate (DMF) and Aspirin (ASA), inhibits IKKα/β in the NF-κB pathway, exhibiting anti-inflammatory activity by preventing p65 from entering the nucleus. It selectively inhibits cancer stem cell (CSC) activity by reducing the growth of mammospheres and the expression of the CD44+CD24- immune phenotype. Furthermore, GTCpFE targets breast cancer stem cells, crucial in aggressive cancer phenotypes that depend on NFκB and PGE2.Fórmula:C22H20O8Forma y color:SolidPeso molecular:412.39Panaxcerol B
CAS:<p>Panaxcerol B, a monogalactosyl monoacylglycerol, exhibits an IC50 value of 59.4 μM against NO production in LPS-stimulated RAW264.7 cells.</p>Fórmula:C27H46O9Forma y color:SolidPeso molecular:514.65BCL6 ligand-4
CAS:BCL6ligand-4 is a BCL6 ligand used in the synthesis of PROTACs, such as BCL6PROTAC 1.Fórmula:C21H25ClN6O3Forma y color:SolidPeso molecular:444.92NLRP3-IN-7
<p>NLRP3-IN-7 (Compound 36) is a selective inhibitor of the NLRP3 inflammasome and is able to assemble the NLRP3 inflammasome.</p>Fórmula:C18H15ClN2O4S3Forma y color:SolidPeso molecular:454.97HOIPIN-8 sodium
CAS:<p>HOIPIN-8 sodium is a LUBAC inhibitor for the study of inflammatory and immune diseases.</p>Fórmula:C23H15F2N4NaO3Pureza:97.34%Forma y color:SolidPeso molecular:456.38VVD-130037
CAS:VVD-130037 is a KEAP1 activator with potential antitumor activity.VVD-130037 inhibits tumor growth in advanced solid tumors by degrading NRF2.Fórmula:C17H17ClN4O2Pureza:99.01% - 99.92%Forma y color:SolidPeso molecular:344.8UBS109
CAS:<p>UBS109, a curcumin analog, is a DNA demethylating agent in pancreatic cancer that promotes osteoblast differentiation and mineralization.</p>Fórmula:C18H17N3OPureza:99.48%Forma y color:SolidPeso molecular:291.35KI696
CAS:KI696 is a high-affinity probe that potently inhibits the interaction of Keap1 and NRF2.Fórmula:C28H30N4O6SPureza:99.74%Forma y color:SolidPeso molecular:550.63Evixapodlin
CAS:Evixapodlin (PD-1/PD-L1-IN 7) is a human PD-1/PD-L1 protein/protein interaction inhibitor (IC50: 0.213).Evixapodlin has anticancer and antiviral activities.Fórmula:C34H36Cl2N8O4Pureza:99.07%Forma y color:SolidPeso molecular:691.61AM103
CAS:AM103 is an effective and selective inhibitor of FLAP (IC50 = 4.2 nM).Fórmula:C36H38N3NaO4SPureza:99.75%Forma y color:SolidPeso molecular:631.76Antiproliferative agent-22
CAS:<p>Antiproliferative agent-22 is an anticancer compound that shows antiproliferative activity on MCF-7, MDA-MB-231 and MDA-MB-468 cells.</p>Fórmula:C17H13N3O3Pureza:99.20% - 99.27%Forma y color:SolidPeso molecular:307.3Dazostinag disodium
CAS:<p>Dazostinag disodium (TAK-676) is a synthetic novel interferon gene (STING) agonist.Cost-effective and quality-assured.</p>Fórmula:C21H20F2N8Na2O10P2S2Pureza:98.84% - 99.96%Forma y color:SolidPeso molecular:754.482-Selenouracil
CAS:2-Selenouracil is a specialized photosensitizer for photodynamical therapy.Fórmula:C4H4N2OSeForma y color:SolidPeso molecular:175.05NSC23925
CAS:NSC23925 is a selective and effective inhibitor of P-glycoprotein (Pgp).Fórmula:C22H26Cl2N2O2Pureza:98%Forma y color:SolidPeso molecular:421.36PSB-12379
CAS:PSB-12379 is a potent inhibitor of Ecto-5'-Nucleotidase (CD73)(Kis of 9.03 nM (rat) and 2.21 nM (human)).Fórmula:C18H23N5O9P2Pureza:98%Forma y color:SolidPeso molecular:515.35Veledimex
CAS:Veledimex is an oral activator ligand for a proprietary gene therapy promoter system. It is also a moderate inhibitor of and substrate for CYP3A4/5.Fórmula:C27H38N2O3Pureza:98%Forma y color:SolidPeso molecular:438.6
