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Inmunología e inflamación

Inmunología e inflamación

Los inhibidores de inmunología e inflamación son compuestos que modulan la respuesta inmunitaria y los procesos inflamatorios. Estos inhibidores son cruciales para estudiar los mecanismos de regulación inmunitaria, la autoinmunidad y la inflamación crónica, así como para desarrollar tratamientos para enfermedades inflamatorias, alergias y trastornos relacionados con el sistema inmunológico. Al dirigirse a vías clave en el sistema inmunológico, estos inhibidores pueden ayudar a reducir las respuestas inmunitarias excesivas o inadecuadas. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad para apoyar su investigación en inmunología, inflamación y desarrollo terapéutico.

Subcategorías de "Inmunología e inflamación"

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Se han encontrado 3269 productos de "Inmunología e inflamación"

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  • Nrf2 activator-1

    CAS:
    Nrf2 activator-1 activates Nrf2; used for COPD, asthma, ALI, ARDS, pulmonary fibrosis research.
    Fórmula:C30H34N4O6S
    Pureza:97.8%
    Forma y color:Solid
    Peso molecular:578.68
  • PMX 205

    CAS:
    <p>PMX 205 is an effective complement antagonist of the C5a receptor.</p>
    Fórmula:C45H62N10O6
    Pureza:98%
    Forma y color:Solid
    Peso molecular:839.04
  • (-)-10,11-Dihydroxyfarnesol

    CAS:
    (-)-10,11-Dihydroxyfarnesol, from Cryptomarasmius aucubae, inhibits NO production.
    Fórmula:C15H28O3
    Forma y color:Solid
    Peso molecular:256.38
  • Inflexuside A

    CAS:
    Inflexuside A, an abietane diterpenoid from Isodon inflexus, and Inflexuside B inhibit NO in LPS-stimulated RAW264.7 cells.
    Fórmula:C26H42O9
    Forma y color:Solid
    Peso molecular:498.61
  • JPE-1375

    CAS:
    JPE-1375: a C5aR1 antagonist, blocks leukocyte mobilization (EC50=6.9 µM), lowers TNF in mice (EC50=4.5 µM), useful for autoimmune/inflammation research.
    Fórmula:C49H63FN10O9
    Forma y color:Solid
    Peso molecular:955.08
  • Biotin-labeled ODN 2216 sodium


    Biotin-labeled ODN 2216 (sodium) serves as a specific agonist for human TLR9 (toll-like receptor 9), facilitating the assessment of CpG ODN cellular uptake and
    Forma y color:Odour Solid
  • diABZI-V/C-DBCO


    <p>Compound 3 (diABZI-V/C-DBCO) functions as an efficient STING agonist. This compound acts by releasing diABZI-amine under the action of cathepsin B to activate STING, thereby inducing the production of interferon and other immune-activating molecules, which enhances the immune system's response to tumors. In THP1-Dual cells, the EC50 values for STING activation by diABZI-V/C-DBCO and diABZI-amine are 1.47 nM and 0.144 nM, respectively, and in primary mouse splenic cells, the EC50 values are 7.7 µM and 0.17 µM, respectively. diABZI-V/C-DBCO is useful for research in the field of cancer immunotherapy.</p>
    Fórmula:C78H89N19O13
    Forma y color:Solid
    Peso molecular:1500.66
  • TLR7 agonist 24


    TLR7 agonist24 (Compound 21) is an agonist of TLR7 with an EC50 of 3.72 μM. When combined with Aluminum Hydroxide, it can be employed as a vaccine adjuvant to enhance the immune response to antigens from SARS-CoV-2 and hepatitis B.
    Forma y color:Odour Solid
  • G3-C12

    CAS:
    G3-C12 shows anticancer activity. is a galectin-3 binding peptide, with Kd of 88 nM.
    Fórmula:C74H115N23O23S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1758.99
  • Tuparstobart

    CAS:
    Tuparstobart (Incagn-02385) is an IgG1κ monoclonal antibody that targets the immune checkpoint receptor protein LAG-3, which is predominantly expressed on
    Forma y color:Liquid
  • Ara-F-NAD+ sodium


    Ara-F-NAD+ sodium, an arabino analogue of NAD+, serves as a potent, reversible, and slow-binding inhibitor of the CD38 NADase [1] [2].
    Fórmula:C21H25FN7NaO13P2
    Forma y color:Solid
    Peso molecular:687.4
  • Citrullinated LL-37 1cit


    Citrullinated LL-37 1cit, a modified LL-37 peptide, retains the antiviral properties of its parent compound against human rhinovirus and exhibits antibacterial
    Fórmula:C205H339N59O54
    Forma y color:Solid
    Peso molecular:4494.25
  • mPGES-1/5-LOX-IN-1


    mPGES-1/5-LOX-IN-1 (compound 3j) is a potent, orally active dual inhibitor of mPGES-1 and 5-LOX, with IC50 values of 0.92 and 1.89 µM, respectively. Additionally, mPGES-1/5-LOX-IN-1 exhibits anti-inflammatory properties.
    Fórmula:C20H22N4O6S
    Peso molecular:446.12601
  • UNC9036


    <p>UNC9036 is a PROTAC degrader of STING, with a DC50 value of 227 nM. The degradation of STING mediated by UNC9036 is dependent on the proteasomal VHL pathway.</p>
    Fórmula:C73H95N17O11S
    Peso molecular:1417.71177
  • Timosaponin E2

    CAS:
    Timosaponin E2 is an anti-inflammatory agent that inhibits active oxygen production [1].
    Fórmula:C46H78O20
    Forma y color:Solid
    Peso molecular:951.1
  • GB1908


    <p>GB1908 is a selective oral inhibitor of galectin-1 (galectin-1), with Ki values of 57 nM for human galectin-1 and 72 nM for mouse galectin-1. It demonstrates over 50-fold selectivity for galectin-1 compared to galectin-3. GB1908 can be utilized in lung cancer research.</p>
    Fórmula:C18H18Cl2N4O5S2
    Peso molecular:504.00957
  • dsVACV-70mer sodium


    <p>dsVACV-70mer sodium is a 70 base pair double-stranded oligonucleotide that contains a viral DNA motif derived from vaccinia virus DNA. It effectively induces IFN-β through a STING-dependent mechanism.</p>
  • Nω-Propyl-L-arginine

    CAS:
    Nω-Propyl-L-arginine, a powerful and specific inhibitor of neuronal nitric oxide synthase (nNOS), effectively inhibits nNOS with a Ki of 57 nM.
    Fórmula:C9H20N4O2
    Forma y color:Solid
    Peso molecular:216.28
  • 7-O-Methylaloeasinol

    CAS:
    7-O-Methylaloeasinol is a useful organic compound for research related to life sciences. The catalog number is T126468 and the CAS number is 105317-69-9.
    Fórmula:C20H26O9
    Forma y color:Solid
    Peso molecular:410.419
  • EX-A5758

    CAS:
    <p>EX-A5758: novel nNOS-NOS1AP inhibitor, reduces pain &amp; enhances paclitaxel's anti-tumor effect.</p>
    Fórmula:C10H17NO5
    Pureza:99.67%
    Forma y color:Solid
    Peso molecular:231.25