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Inmunología e inflamación

Inmunología e inflamación

Los inhibidores de inmunología e inflamación son compuestos que modulan la respuesta inmunitaria y los procesos inflamatorios. Estos inhibidores son cruciales para estudiar los mecanismos de regulación inmunitaria, la autoinmunidad y la inflamación crónica, así como para desarrollar tratamientos para enfermedades inflamatorias, alergias y trastornos relacionados con el sistema inmunológico. Al dirigirse a vías clave en el sistema inmunológico, estos inhibidores pueden ayudar a reducir las respuestas inmunitarias excesivas o inadecuadas. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad para apoyar su investigación en inmunología, inflamación y desarrollo terapéutico.

Subcategorías de "Inmunología e inflamación"

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Se han encontrado 3054 productos de "Inmunología e inflamación"

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  • Rademikibart

    CAS:
    <p>Rademikibart (CBP-201) is a human monoclonal antibody selective for IL-4Rα, exhibiting strong affinity with a KD of 20.7 pM for human IL-4Rα epitopes, without</p>
    Pureza:95%
    Forma y color:Liquid
  • Avizakimab

    CAS:
    <p>Avizakimab (BOS161721) is a humanized lgG1 monoclonal antibody IL-21, with potential for the treatment of systemic lupus erythematosus (SLE).</p>
    Pureza:95% - 95%
    Forma y color:Liquid
  • CC-90002

    CAS:
    <p>CC-90002: humanized anti-CD47 mAb, high affinity, subnanomolar Kd. For hematologic and solid tumor research.</p>
    Forma y color:Liquid
  • QNZ

    CAS:
    Fórmula:C22H20N4O
    Pureza:>98.0%(HPLC)
    Forma y color:White to Light yellow to Green powder to crystal
    Peso molecular:356.43

    Ref: 3B-Q0109

    5mg
    92,00€
    25mg
    314,00€
  • Indometacin Farnesil

    CAS:
    Fórmula:C34H40ClNO4
    Pureza:>98.0%(HPLC)
    Forma y color:Light yellow to Yellow to Orange clear liquid
    Peso molecular:562.15

    Ref: 3B-I0943

    100mg
    414,00€
  • Azathioprine

    CAS:
    Fórmula:C9H7N7O2S
    Pureza:>98.0%(T)(HPLC)
    Forma y color:Light yellow to Yellow to Green powder to crystal
    Peso molecular:277.26

    Ref: 3B-A2069

    5g
    229,00€
  • Serotonin Creatinine Sulfate Monohydrate

    CAS:
    Fórmula:C14H19N5O2·H2SO4·H2O
    Pureza:>98.0%(T)
    Forma y color:White to Light yellow powder to crystal
    Peso molecular:405.43

    Ref: 3B-S0036

    1g
    69,00€
  • Nepafenac-d5

    CAS:
    <p>Nepafenac D5 is the deuterium labeled Nepafenac, which is a selective inhibitor of COX-2 .</p>
    Fórmula:C15H14N2O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:259.31
  • Maresin 1

    CAS:
    Maresin 1 is biosynthesized by macrophages (MΦ) and possesses significant anti-inflammatory activity that attenuates LPS-induced lung injury in mice.
    Fórmula:C22H32O4
    Forma y color:Solid
    Peso molecular:360.49
  • Ketorolac-d5

    CAS:
    <p>Ketorolac-d5 is a deuterated compound of ketorolac for isotope tracing. Ketorolac is a non-steroidal anti-inflammatory agent and inhibitor of COX-1 and COX-2.</p>
    Fórmula:C15H8D5NO3
    Pureza:98.99%
    Forma y color:Solid
    Peso molecular:260.3
  • Lusvertikimab

    CAS:
    <p>Lusvertikimab (OSE-127) is a humanized anti-IL7R antibody with anti-leukemic efficacy and can be used to study leukemia.</p>
    Pureza:95% - 98.4% (SDS-PAGE); 99% (SEC-HPLC)
    Forma y color:Liquid
  • BMS-378806

    CAS:
    BMS-378806 (BMS-806) selectively inhibits the binding of HIV-1 gp120 to the CD4 receptor with EC50 of 0.85-26.5 nM in virus.
    Fórmula:C22H22N4O4
    Pureza:99.93%
    Forma y color:Solid
    Peso molecular:406.43
  • Vopikitug

    CAS:
    <p>Vopikitug is a humanized monoclonal antibody targeting IL-2RA with antitumor activity. It can be used to study cancer.</p>
    Pureza:99.1% (SDS-PAGE); 96.5% (SEC-HPLC) - 99.1% (SDS-PAGE); 96.5% (SEC-HPLC)
    Forma y color:Liquid
  • (9α,13α,14α)-4-Hydroxy-3,7-dimethoxy-7,8-didehydromorphinan-6-one

    CAS:
    (9α,13α,14α)-4-Hydroxy-3,7-dimethoxy-7,8-didehydromorphinan-6-one is a major mechanism of Sinomenine.
    Fórmula:C18H21NO4
    Pureza:97.85%
    Forma y color:Soild
    Peso molecular:315.36
  • D228

    CAS:
    <p>D228 is an oral anti-inflammatory,inhibi B and T lymphocytes, down-regulation of MyD88/TRAF6/p38 and up-regulation of IL-10,inflammatory bowel disease (IBD).</p>
    Fórmula:C22H28O12
    Pureza:99.91%
    Forma y color:Solid
    Peso molecular:484.45
  • Amfenac

    CAS:
    <p>Amfenac promotes apoptosis in ARPE-19 cell culture.</p>
    Fórmula:C15H13NO3
    Forma y color:Solid
    Peso molecular:255.27
  • Avasopasem manganese

    CAS:
    <p>Avasopasem manganese is a drug candidate of superoxide dismutase mimetic.</p>
    Fórmula:C21H35Cl2MnN5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:483.38
  • TMV-IN-9

    CAS:
    <p>TMV-IN-9 (compound A6) is an antiviral agent that exhibits exceptional inactivation effects against Tobacco Mosaic Virus (TMV), with an EC50 of 62.8 μg/mL. It demonstrates strong binding capabilities to the TMV capsid protein, with a binding affinity of 1.862 μM. Moreover, TMV-IN-9 significantly disrupts the integrity of TMV particles, thereby preventing the virus from infecting the host.</p>
    Fórmula:C20H20O8
    Forma y color:Solid
    Peso molecular:388.37
  • FAPI-2

    CAS:
    <p>FAPI-2 is a specific inhibitor of fibroblast-activated protein based on the radiotracer FAP labeling, and has anticancer activity.</p>
    Fórmula:C40H56N10O10
    Pureza:98.76%
    Forma y color:Solid
    Peso molecular:836.93
  • 3,4-DAA

    CAS:
    <p>3,4-DAA has anti-inflammatory activity and inhibits EOC20 cell-induced nitric oxide synthase (iNOS) induced by IFN-γ and lipopolysaccharide.</p>
    Fórmula:C18H17NO6
    Pureza:98%
    Forma y color:Solid
    Peso molecular:343.33
  • Azacyclonol hydrochloride

    CAS:
    <p>Azacyclonol hydrochloride can be used in the treatment of chronic schizophrenia.</p>
    Fórmula:C18H22ClNO
    Forma y color:Off White Crystalline Powder
    Peso molecular:303.83
  • AZD4144

    CAS:
    <p>AZD4144 is a potent and selective NLRP3 inhibitor (IC50 = 54 nM) that reducs IL-1β and IL-18 production for immune disorders.</p>
    Fórmula:C18H16F3N3O3
    Pureza:99.02%
    Forma y color:Soild
    Peso molecular:379.33
  • Etokimab

    CAS:
    <p>Etokimab (ANB-020) is a humanised monoclonal antibody targeting IL-33, neutrophil migration, atopic dermatitis, asthma, and sinusitis.</p>
    Pureza:95%
    Forma y color:Liquid
  • AHR-10037

    CAS:
    <p>AHR-10037, a NSAID, offers pain relief, fever reduction, safety, and low stomach risk, acting as a prodrug for COX inhibitors.</p>
    Fórmula:C15H13ClN2O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:288.73
  • Kamebakaurin

    CAS:
    <p>Kamebakaurin combats liver toxicity, cancer, inflammation, and neuroinflammation by blocking NF-κB, HIF-1α, and key signaling pathways.</p>
    Fórmula:C20H30O5
    Pureza:98.05%
    Forma y color:Solid
    Peso molecular:350.45
  • Allopurinol Sodium

    CAS:
    <p>Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.</p>
    Fórmula:C5H4N4NaO
    Pureza:99.93%
    Forma y color:Solid
    Peso molecular:159.1
  • Catalase

    CAS:
    <p>Catalase, an enzyme, metabolizes H2O2 and ROS; its expression and localization change significantly in tumors.</p>
    Pureza:≥98%
    Forma y color:Small Colorless Crystals Or Powder At Room Temperature Almost Odourless Small Colourless Crystals Or A White Crystalline Powder
  • E3330

    CAS:
    <p>E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.</p>
    Fórmula:C21H30O6
    Pureza:99.52%
    Forma y color:Solid
    Peso molecular:378.46
  • Pelubiprofen

    CAS:
    <p>Pelubiprofen is a non-steroidal anti-inflammatory agent and a COX-2 inhibitor, which effectively reduces PGE(2) production by inhibiting COX activity.</p>
    Fórmula:C16H18O3
    Pureza:99.69%
    Forma y color:Solid
    Peso molecular:258.31
  • K-80001

    CAS:
    <p>K-80001 is a selective RXRα ligand and a COX-1/2 inhibitor, exhibiting IC50 values of 82.9μM for RXRα, 3.4μM for COX-1, and 1.2μM for COX-2, respectively [1].</p>
    Fórmula:C20H17FO2
    Forma y color:Solid
    Peso molecular:308.35
  • Avanafil dibesylate

    CAS:
    <p>Avanafil dibesylate is a PDE5 inhibitor.</p>
    Fórmula:C35H38ClN7O9S2
    Forma y color:Solid
    Peso molecular:800.3
  • (R)-MALT1-IN-3

    CAS:
    <p>(R)-MALT1-IN-3 (121) inhibits MALT1 protease (IC50: 20 nM) and IL6/IL10 in OCI-LY3 (IC50: 60/40 nM).</p>
    Fórmula:C21H19F3N8O2
    Forma y color:Solid
    Peso molecular:472.42
  • COX-2-IN-17

    CAS:
    <p>COX-2-IN-17 is a potent, blood-brain barrier permeable COX-2 (cyclooxygenase-2) inhibitor (IC50: 0.02 μM) with anti-inflammatory and analgesic activity.</p>
    Fórmula:C20H23ClN6O2
    Forma y color:Solid
    Peso molecular:414.89
  • AXC-715 trihydrochloride

    CAS:
    <p>AXC-715 trihydrochloride is a TLR7/8 agonist used to make PD-L1 adjuvanted antibody immunocouplings.</p>
    Fórmula:C18H28Cl3N5
    Pureza:99.74%
    Forma y color:Solid
    Peso molecular:420.81
  • Naproxen glucuronide

    CAS:
    <p>Naproxen glucuronide: NSAID, propionic class, eases pain, fever, inflammation. Nonselective COX blocker.</p>
    Fórmula:C20H22O9
    Forma y color:Solid
    Peso molecular:406.38
  • CHD-5

    CAS:
    <p>CHD-5 is a selective antagonist of the aryl hydrocarbon receptor (AhR).</p>
    Fórmula:C19H17N3O2
    Forma y color:Solid
    Peso molecular:319.36
  • IRAK4-IN-22

    CAS:
    <p>IRAK4-IN-22: oral IRAK4 inhibitor, IC50: IRAK4-3nM, TAK1-17nM, disrupts IL-23, targets autoimmune diseases.</p>
    Fórmula:C28H28FN7O2
    Forma y color:Solid
    Peso molecular:513.57
  • Enflicoxib

    CAS:
    <p>Enflicoxib is an effective treatment for canine osteoarthritis pain and inflammation, with faster onset than mavacoxib, improving veterinary outcomes.</p>
    Fórmula:C16H12F5N3O2S
    Pureza:99.88%
    Forma y color:Solid
    Peso molecular:405.34
  • MIF-IN-4 hydrochloride

    CAS:
    <p>MIF-IN-4 hydrochloride inhibits MIF, a cytokine; has pIC50 of 5.01-6, affecting macrophage movement.</p>
    Fórmula:C26H29ClN6O2
    Forma y color:Solid
    Peso molecular:493.01
  • TML-6

    CAS:
    <p>TML-6, an oral derivative of curcumin, may help in Alzheimer's research by targeting amyloid production and various molecular pathways.</p>
    Fórmula:C30H37NO7
    Pureza:99.71%
    Forma y color:Solid
    Peso molecular:523.62
  • Tilarginine citrate

    CAS:
    <p>Tilarginine citrate is a competitive nitric oxide synthetase inhibitor.</p>
    Fórmula:C13H24N4O9
    Pureza:98%
    Forma y color:Solid
    Peso molecular:380.354
  • NPD926

    CAS:
    <p>NPD926 is an inducer of cancel cell death.</p>
    Fórmula:C29H35ClN2O2
    Forma y color:Solid
    Peso molecular:479.05
  • Avenanthramide-C methyl ester

    CAS:
    <p>Avenanthramide-C methyl ester blocks IKK/IκB phosphorylation, inhibits NF-κB, and reduces IL-6, IL-8, MCP-1 in endothelial cells (IC50 ~40 μM).</p>
    Fórmula:C17H15NO6
    Forma y color:Solid
    Peso molecular:329.3
  • Loxoprofenol-SRS tromethamine

    CAS:
    <p>Loxoprofenol-SRS tromethamine (HR1405-01), a metabolite of Loxoprofen, is a safe IV NSAID with strong anti-inflammatory and pain relief properties.</p>
    Fórmula:C19H31NO6
    Forma y color:Solid
    Peso molecular:369.45
  • HE 3286

    CAS:
    <p>Triolex, an NF-kB inhibitor, is used potentially for the treatment of rheumatoid arthritis, ulcerative colitis.</p>
    Fórmula:C21H30O3
    Forma y color:Solid
    Peso molecular:330.46
  • COX-2-IN-21

    CAS:
    <p>COX-2-IN-21 (Compound 5c) is an orally active, selective COX-2 inhibitor (IC50: 0.039 μM). COX-2-IN-21 has good anti-inflammatory potential.</p>
    Fórmula:C21H22N6O4
    Forma y color:Solid
    Peso molecular:422.44
  • NF-κB-IN-3

    CAS:
    <p>NF-κB-IN-3 (Compound 2) is an NF-κB inhibitor (IC50: 0.70 μM) and can be used as an anti-tumour agent.</p>
    Fórmula:C24H18ClF3N2O2
    Forma y color:Solid
    Peso molecular:458.86
  • 3-OH-Kynurenamine dihydroiodide

    CAS:
    <p>3-OH-Kynurenamine dihydroiodide, the dihydroiodide form of 3-OH-Kynurenamine, functions as an activator of the aryl hydrocarbon receptor (AhR), thereby modulating the immune response. It enhances the expression of Ido1 and Tgfb1, reducing skin inflammation in psoriasis mouse models and kidney damage in nephrotoxic lupus mouse models .</p>
    Fórmula:C9H14I2N2O2
    Forma y color:Solid
    Peso molecular:436.03
  • AChE/Nrf2 modulator 1

    CAS:
    <p>AChE/Nrf2 modulator 1: oral, targets AChE/Nrf2, IC50s: 0.07 μM (eeAChE), 0.38 μM (hAChE); for Alzheimer's research.</p>
    Fórmula:C27H27FN4O2
    Forma y color:Solid
    Peso molecular:458.53
  • Nrf2 activator-5

    CAS:
    <p>Nrf2 activator-5 combats oxidative stress and inflammation in microglia, with potent antioxidant effects.</p>
    Fórmula:C25H30Cl2O6
    Forma y color:Solid
    Peso molecular:497.41
  • Antimicrobial agent-2

    CAS:
    <p>Compound V-a: broad-spectrum, low-toxicity antimicrobial with no resistance, high bioavailability, damages membranes, targets MRSA (MIC 1μg/mL).</p>
    Fórmula:C16H14N2O4S
    Forma y color:Solid
    Peso molecular:330.36
  • NLRP3-IN-25

    CAS:
    <p>NLRP3-IN-25 (compound 32), an orally available NLRP3 inhibitor, exhibits anti-inflammatory properties by attenuating renal injury in a mouse model of doxorubicin-induced glomerulonephritis and inhibiting IL-1β secretion in THP-1 cells, with an IC 50 value of 21 nM [1].</p>
    Fórmula:C17H19F3N4O5S
    Forma y color:Solid
    Peso molecular:448.42
  • iNOs-IN-3

    CAS:
    <p>iNOs-IN-3: oral iNOS inhibitor, IC50 = 3.342 μM, anti-inflammatory, for LPS-induced ALI study.</p>
    Fórmula:C27H24N2O5S
    Forma y color:Solid
    Peso molecular:488.55
  • Keap1-Nrf2-IN-11

    CAS:
    <p>Keap1-Nrf2-IN-11 (6k) inhibits Keap1-Nrf2, KD 0.21 nM; reduces ROS, NO, TNF-α; aids anti-inflammatory research.</p>
    Fórmula:C36H43N7O8S2
    Forma y color:Solid
    Peso molecular:765.9
  • 10-Cl-BBQ

    CAS:
    <p>10-Cl-BBQ is a ligand of aryl hydrocarbon receptor (AhR).</p>
    Fórmula:C18H9ClN2O
    Forma y color:Solid
    Peso molecular:304.73
  • IKK2-IN-4

    CAS:
    <p>IKK2-IN-4(IKK2 Inhibitor VI) is a highly potent IKK-2 inhibitor with an IC50 value of 25 nM. IKK2-IN-4 inhibited the production of TNF-α in PBMC induced by LPS.</p>
    Fórmula:C12H11N3O2S
    Pureza:>99.99%
    Forma y color:Solid
    Peso molecular:261.3
  • NXPZ-2

    CAS:
    <p>NXPZ-2, an oral Keap1-Nrf2 PPI inhibitor (Ki: 95 nM, EC50: 120-170 nM), may improve cognition and neuron health in AD.</p>
    Fórmula:C27H27N5O7S2
    Forma y color:Solid
    Peso molecular:597.66
  • APHS

    CAS:
    <p>APHS is a cyclooxygenase-2 (COX-2) inhibitor with anti-inflammatory action. It also more potent than aspirin in the inhibition of COX-1.</p>
    Fórmula:C15H18O2S
    Forma y color:Solid
    Peso molecular:262.37
  • Keap1-Nrf2-IN-12

    CAS:
    <p>eap1-Nrf2-IN-12 is a potent inhibitor of Keap1-Nrf2 (IC50: 2.30 μM). eap1-Nrf2-IN-12 is metabolically stable in human liver microsomes.</p>
    Fórmula:C26H28N2O10S2
    Forma y color:Solid
    Peso molecular:592.64
  • Piroxicam cinnamate

    CAS:
    <p>Cinnoxicam is a COX inhibitor used for bone/joint inflammation, rheumatic issues, and varicocele-related oligospermia.</p>
    Fórmula:C24H19N3O5S
    Forma y color:Solid
    Peso molecular:461.49
  • IT-901

    CAS:
    <p>IT-901: Oral NF-κB c-Rel inhibitor, IC50 0.1 µM. Blocks c-Rel/DNA binding, IC50 3 µM. Antitumor naphthalene derivative for lymphoma/myeloma therapy.</p>
    Fórmula:C17H14N2O4S
    Pureza:98.06%
    Forma y color:Solid
    Peso molecular:342.37
  • P2X7-IN-2

    CAS:
    <p>P2X7-IN-2 is a P2X7 receptor blocker, halts IL-Iβ release (IC50: 0.01 nM), researched for autoimmunity and heart issues.</p>
    Fórmula:C22H21F4N3O2
    Forma y color:Solid
    Peso molecular:435.41
  • PT4

    CAS:
    <p>PT4: treats CL, disrupts parasite mitochondria, kills Leishmania spp., IC50- L. amazonensis 125.18 μM, L. braziliensis 233.18 μM, anti-inflammatory.</p>
    Fórmula:C18H14N4O2
    Forma y color:Solid
    Peso molecular:318.33
  • COX-2/5-LOX-IN-2

    CAS:
    <p>COX-2/5-LOX-IN-2, a benzothiophen derivative, inhibits COX-1, COX-2, 5-LOX with IC50s of 5.40, 0.01, 1.78 μM. More effective than Celecoxib, Indomethacin.</p>
    Fórmula:C18H13N3O4S2
    Forma y color:Solid
    Peso molecular:399.44
  • DMX-129

    CAS:
    <p>DMX-129 is a chemical compound acting as an inhibitor for both ΙΚΚε and TBK-1, demonstrating efficacy with IC50 values of below 30 nM for each [1].</p>
    Fórmula:C19H17FN8
    Forma y color:Solid
    Peso molecular:376.39
  • CAY10589

    CAS:
    <p>CAY10589 is an mPGES-1 inhibitor.</p>
    Fórmula:C25H28ClN3O2S
    Forma y color:Solid
    Peso molecular:470.03
  • COX-2-IN-19

    CAS:
    <p>COX-2-IN-19, a potent COX-2 inhibitor, IC50 of 1.76 μM, has strong anti-inflammatory effects in vivo.</p>
    Fórmula:C18H18N4O2S
    Forma y color:Solid
    Peso molecular:354.43
  • COX-2-IN-24

    CAS:
    <p>COX-2-IN-24 is an orally active COX-2 inhibitor (IC50: 0.17 μM) with anti-inflammatory and hypo-ulcerogenic effects.</p>
    Fórmula:C24H24BrN5O3S2
    Forma y color:Solid
    Peso molecular:574.51
  • L-NMMA acetate

    CAS:
    L-NMMA acetate inhibits all NOS types (nNOS, eNOS, iNOS); Ki: 0.18, 0.4, 6 µM respectively.
    Fórmula:C9H20N4O4
    Pureza:99.72% - 99.8%
    Forma y color:White To Off-White Solid
    Peso molecular:248.28
  • PPM-18

    CAS:
    <p>PPM-18 (NSC 73233), a potent anti-inflammatory, inhibits iNOS and NF-κB binding; also suppresses bladder cancer cell growth.</p>
    Fórmula:C17H11NO3
    Forma y color:Solid
    Peso molecular:277.27
  • 1-Dehydro-[10]-gingerdione

    CAS:
    <p>1-Dehydro-[10]-gingerdione blocks IKKβ, curbs IκBα phosphorylation, halts NF-κB activity, and aids inflammation research.</p>
    Fórmula:C21H30O4
    Forma y color:Solid
    Peso molecular:346.46
  • IRAK4-IN-13

    CAS:
    <p>IRAK4-IN-13 (compound 21) is a potent IRAK4 inhibitor, IC50 0.6 nM, with high HLM clearance at 96 μL/min/mg.</p>
    Fórmula:C24H27N9O
    Forma y color:Solid
    Peso molecular:457.53
  • COX-2-IN-23

    CAS:
    <p>COX-2-IN-23 selectively inhibits COX-2 (IC50=0.28μM), weakly affects COX-1 (IC50=20.14μM), and has anti-inflammatory and low ulcerogenic properties.</p>
    Fórmula:C24H25N5O3S2
    Forma y color:Solid
    Peso molecular:495.62
  • IFN α-IFNAR-IN-1

    CAS:
    <p>Nonpeptidic IFN-α/IFNAR blocker, halts MVA-triggered BM-pDC IFN-α response; IC50: 2-8 μM.</p>
    Fórmula:C18H17NS
    Pureza:98%
    Forma y color:Solid
    Peso molecular:279.4
  • COX-1/2-IN-3

    CAS:
    <p>COX-1/2-IN-3 (Compound 7a) is a dual inhibitor of COX-1 and COX-2. COX-1/2-IN-3 has anti-inflammatory activity with low toxicity [1].</p>
    Fórmula:C14H8N2O8
    Forma y color:Solid
    Peso molecular:332.22
  • Z-VRPR-FMK

    CAS:
    <p>Z-VRPR-FMK: irreversible MALT1 inhibitor, halts growth/invasion of diffused B-cell lymphoma by blocking NF-κB activation and MMP expression.</p>
    Fórmula:C31H49FN10O6
    Forma y color:Solid
    Peso molecular:676.78
  • COX-1/2-IN-1

    CAS:
    <p>"COX-1/2-IN-2: Strong dual inhibitor of COX-1 (IC50 = 13.9 μM) and COX-2 (IC50 = 6.4 μM)."</p>
    Fórmula:C15H10BrClN2O
    Forma y color:Solid
    Peso molecular:349.61
  • β-Nor-lapachone

    CAS:
    β-Nor-lapachone is an antibiofilm agent of Candida glabrata.
    Fórmula:C14H12O3
    Forma y color:Solid
    Peso molecular:228.24
  • Keap1-Nrf2-IN-14

    CAS:
    <p>Keap1-Nrf2-IN-14, a KEAP1-NRF2 inhibitor (IC50: 75 nM, Kd: 24 nM), boosts NRF2 gene expression, antioxidative and anti-inflammatory response.</p>
    Fórmula:C30H29NO8S
    Forma y color:Solid
    Peso molecular:563.62
  • COX-2/sEH-IN-1

    CAS:
    <p>COX-2/sEH-IN-1, oral dual inhibitor: COX-2 (IC50=1.24 μM), sEH (IC50=0.40 μM); boosts anti-inflammatory action, cuts heart risk.</p>
    Fórmula:C23H18F3N5O3S
    Forma y color:Solid
    Peso molecular:501.48
  • Veledimex (S enantiomer)

    CAS:
    Veledimex S is the oral S enantiomer of a gene therapy promoter activator and CYP3A4/5 inhibitor.
    Fórmula:C27H38N2O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:438.6
  • PNRI-299

    CAS:
    <p>PNRI-299 is a selective inhibitor of AP-1 transcription(IC50 of 20 uM ).</p>
    Fórmula:C21H15N5O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:401.37
  • Naphazoline

    CAS:
    <p>Naphazoline (Naphcon-a) is a sympathomimetic compound with marked alpha adrenergic activity.</p>
    Fórmula:C14H14N2
    Pureza:99.79%
    Forma y color:White Crystalline Powder Solid
    Peso molecular:210.27
  • Safrole oxide

    CAS:
    <p>Safrole oxide inhibits neuronal growth, induces apoptosis, elevates COX-2, IL-8, ROS, promoting endothelial-to-neuron-like cell transdifferentiation.</p>
    Fórmula:C10H10O3
    Pureza:100%
    Forma y color:Solid
    Peso molecular:178.18
  • Vidarabine phosphate

    CAS:
    Vidarabine phosphate is an adenosine monophosphate analog.
    Fórmula:C10H14N5O7P
    Pureza:99.75%
    Forma y color:White Crystalline Powder
    Peso molecular:347.22
  • TMV-IN-1

    CAS:
    <p>TMV-IN-1: a chalcone inhibits TMV with EC50s of 70.7 and 60.8 μg/mL, applicable in infection and tumor studies.</p>
    Fórmula:C28H26O4
    Forma y color:Solid
    Peso molecular:426.5
  • TLR7/8 agonist 6

    CAS:
    <p>Compound 4: Imidazoquinoline, potent TLR7/8 agonist, IC50: 0.18μM (TLR7), 5.34μM (TLR8).</p>
    Fórmula:C24H27N5O2
    Forma y color:Solid
    Peso molecular:417.5
  • APC-0576

    CAS:
    <p>APC-0576, an (S,S)-isomer, blocks NF-kappaB gene activation and may reduce inflammation in human cells.</p>
    Fórmula:C23H27N3O3
    Forma y color:Solid
    Peso molecular:393.48
  • COX-2-IN-20

    CAS:
    <p>COX-2-IN-20 (Compound 5d) is a selective and orally active inhibitor of COX-2 (IC 50 = 17.9 nM) with anti-inflammatory activity [1].</p>
    Fórmula:C11H9ClFN3O2
    Forma y color:Solid
    Peso molecular:269.66
  • C5aR-IN-2

    CAS:
    <p>C5aR-IN-2, a potent C5aR inhibitor, shows promise for researching inflammatory diseases.</p>
    Fórmula:C36H40FN5O2
    Forma y color:Solid
    Peso molecular:593.73
  • Keap1-Nrf2-IN-13

    CAS:
    <p>Keap1-Nrf2-IN-13 is a PPI inhibitor (IC50: 0.15 μM) that binds Keap1 strongly, useful for oxidative stress and inflammation research.</p>
    Fórmula:C28H32N2O10S2
    Forma y color:Solid
    Peso molecular:620.69
  • c-di-AMP

    CAS:
    <p>c-di-AMP (Cyclic diadenylate) is a STING agonist. It binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway.</p>
    Fórmula:C20H24N10O12P2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:658.41
  • BC12-4

    CAS:
    <p>BC12-4 is a novel potent inhibitor of IL-2 secretion, it has potent immunomodulatory activity.</p>
    Fórmula:C19H14N2O3
    Forma y color:Solid
    Peso molecular:318.33
  • STING modulator-4

    CAS:
    STING modulator-4: competitive, Ki=0.0933 μM (R232H STING), EC50 >10 μM (p-IRF3, THP-1 cells).
    Fórmula:C17H18N8O
    Forma y color:Solid
    Peso molecular:350.38
  • L-Kynurenine sulfate

    CAS:
    <p>L-Kynurenine sulfate activates AHR, leading naive T cells to anti-inflammatory Treg phenotype.</p>
    Fórmula:C10H14N2O7S
    Forma y color:Solid
    Peso molecular:306.29
  • OPC-163493

    CAS:
    <p>OPC-163493 is an orally active, liver-targeted mitochondrial uncoupling agent that diminishes Δψ (delta psi) and mitochondrial ROS (reactive oxygen species)</p>
    Fórmula:C14H8F3N5S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:335.31
  • HPGDS inhibitor 3

    CAS:
    <p>HPGDS inhibitor 3: oral, potent (IC50=9.4 nM; EC50=42 nM), selective, no CNS toxicity, good pharmacokinetics, anti-inflammatory.</p>
    Fórmula:C21H27N3O2
    Forma y color:Solid
    Peso molecular:353.46
  • IRAK4-IN-17

    CAS:
    <p>IRAK4-IN-17 is a potent IRAK4 inhibitor with a 1.3 nM IC50, key for DLBCL research.</p>
    Fórmula:C17H20F2N8O
    Forma y color:Solid
    Peso molecular:390.39
  • T-5342126

    CAS:
    <p>T-5342126: TLR4 antagonist, lowers LPS-induced NO in cells (IC50=27.8 μM) &amp; cytokines in blood, cuts ethanol intake &amp; Iba1 in mice.</p>
    Fórmula:C25H32ClN3O3
    Forma y color:Solid
    Peso molecular:457.99
  • Nω-Propyl-L-arginine hydrochloride

    CAS:
    <p>Highly selective and potent inhibitor of nNOS (Ki = 57 nM). Displays 3158-fold and 149-fold selectivity over iNOS and eNOS respectively. Hypotensive in vivo.</p>
    Fórmula:C9H21ClN4O2
    Forma y color:Solid
    Peso molecular:252.74
  • APY0201

    CAS:
    <p>APY0201: potent, specific ATP-competitive PIKfyve inhibitor; IC50=5.2 nM; blocks PtdIns3P to PtdIns(3,5)P2 conversion.</p>
    Fórmula:C23H23N7O
    Pureza:98% - 99.74%
    Forma y color:Solid
    Peso molecular:413.48
  • TYT-1

    CAS:
    <p>TYT-1 is a West Nile virus (WNV) inhibitor, antiviral (IC₅₀ = 0.7 mM) by blocking the pre-assembly replication step following viral entry into cells.</p>
    Fórmula:C21H17N3O2S3
    Pureza:98.49%
    Forma y color:Solid
    Peso molecular:439.57
  • L 669083

    CAS:
    <p>L 669083 is two classes of potent leukotriene biosynthesis inhibitors photoaffinity analogue.</p>
    Fórmula:C29H29IN4O5S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:672.54
  • LY 150310

    CAS:
    <p>LY 150310, a histamine H1-receptor antagonist, can alter prostanoid concentrations in vitro and in vivo.</p>
    Fórmula:C13H14N2
    Forma y color:Solid
    Peso molecular:198.26
  • Fagaramide

    CAS:
    <p>Fagaramide possesses Antiplasmodial activity.</p>
    Fórmula:C14H17NO3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:247.29
  • NCX-6560

    CAS:
    NCX-6560 is a novel NO-releasing derivative of atorvastatin, with those of atorvastatin.
    Fórmula:C37H42FN3O8
    Forma y color:Solid
    Peso molecular:675.74
  • ZXX2-77

    CAS:
    <p>ZXX2-77 is a cyclooxygenase-1 inhibitor.</p>
    Fórmula:C13H13ClN2O2S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:296.77
  • Tiazotic acid

    CAS:
    <p>Tiazotic acid is an agent with the activity of antioxidant.</p>
    Fórmula:C5H7N3O2S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:173.19
  • L 748780

    CAS:
    <p>L 748780 is a selective inducible COX-2 inhibitor.</p>
    Fórmula:C19H14Cl3NO4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:426.68
  • Oxyfenamate

    CAS:
    Oxyfenamate has anti-anxiety actions. It is also used in anxiety neuroses.
    Fórmula:C11H15NO3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:209.24
  • Anisodine hydrobromide

    CAS:
    <p>Anisodine hydrobromide is an inhibitor of adenosine kinase.</p>
    Fórmula:C17H22BrNO5
    Forma y color:White Crystals Or Crystalline Powder
    Peso molecular:400.27
  • Eltrombopag methyl ester

    CAS:
    <p>Eltrombopag methyl ester, a Tpo receptor agonist derivative, boosts platelet production for thrombocytopenia research.</p>
    Fórmula:C26H24N4O4
    Forma y color:Solid
    Peso molecular:456.49
  • FR20

    CAS:
    <p>FR20 is a human microsomal prostaglandin synthase 1 (mPGES 1) inhibitor.</p>
    Fórmula:C31H25Cl2N3O2
    Forma y color:Solid
    Peso molecular:542.46
  • LC-R 505

    CAS:
    <p>LC-R 505 is an anti-inflammatory.</p>
    Fórmula:C20H26N2O5S
    Forma y color:Solid
    Peso molecular:406.5
  • NCX1022

    CAS:
    <p>NCX1022 is a NO-releasing derivative of Hydrocortisone. It is the most widely used anti-inflammatory drug for the treatment of skin inflammation.</p>
    Fórmula:C29H35NO9
    Pureza:98%
    Forma y color:Solid
    Peso molecular:541.59
  • GSK223

    CAS:
    GSK223 is an iE-DAP-stimulated IL-8 release inhibitor via the NOD1 signaling pathway.
    Fórmula:C21H18FN3O3S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:443.51
  • MIP-1072

    CAS:
    <p>MIP-1072 is the prostate-specific membrane antigen inhibitor.</p>
    Fórmula:C19H26IN3O7
    Pureza:98%
    Forma y color:Solid
    Peso molecular:535.33
  • Cyclic-di-GMP diammonium

    CAS:
    <p>C-di-GMP diammonium activates STING, regulates biofilms, motility, and virulence in bacteria.</p>
    Fórmula:C20H30N12O14P2
    Forma y color:Solid
    Peso molecular:724.47
  • hDDAH-1-IN-1

    CAS:
    hDDAH-1-IN-1 is a selective non-amino acid catalytic site inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) (Ki: 18 μM).
    Fórmula:C8H20N4O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:188.27
  • BPK-29

    CAS:
    BPK-29 disrupts NR0B1 binding and modifies C274, inhibiting growth in KEAP1-mutant cancers.
    Fórmula:C26H32ClN3O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:470
  • UPF-648 sodium salt

    CAS:
    <p>UPF-648 sodium salt is an inhibitor of kynurenine 3-monooxygenase (KMO) and exhibits highly active at 1 uM (81 ± 10% KMO inhibition).</p>
    Fórmula:C11H8Cl2NaO3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:282.07
  • AHR-6293

    CAS:
    <p>AHR-6293 is used to distinguishing the effect of anti-platelet aggregating drug properties and the effect of anti-inflammatory properties.</p>
    Fórmula:C15H12ClNO3
    Forma y color:Solid
    Peso molecular:289.71
  • Tyrosinase-IN-12

    CAS:
    <p>Tyrosinase-IN-12(Non-competitive tyrosinase inhibitor) is a potent non-competitive tyrosinase inhibitor with an IC50 of 49.33 ± 2.64 µM and a Ki of 31.25 ± 0.25</p>
    Fórmula:C16H12ClN3S
    Pureza:99.2%
    Forma y color:Soild
    Peso molecular:313.8
  • QM385

    CAS:
    <p>QM385 is a potent inhibitor of sepiapterin reductase (SPR)(IC50 of 1.49 nM).</p>
    Fórmula:C17H18F3N7O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:409.37
  • NOS-IN-3

    CAS:
    <p>NOS-IN-3: potent, selective iNOS inhibitor; IC50 of 4.6 µM; spares eNOS; low toxicity; potential for septic shock treatment.</p>
    Fórmula:C10H15N3O
    Forma y color:Solid
    Peso molecular:193.25
  • Isoandrographolide

    CAS:
    <p>Isoandrographolide induces cell differentiation, protects the liver, blocks NLRP3, and reduces silicosis in mice.</p>
    Fórmula:C20H30O5
    Forma y color:Solid
    Peso molecular:350.45
  • AN-3485

    CAS:
    <p>AN-3485 is a Toll-Like Receptor(TLR) inhibitor (IC50s: 18 to 580 nM).</p>
    Fórmula:C14H13BClNO3
    Forma y color:Solid
    Peso molecular:289.52
  • PHA-408

    CAS:
    <p>PHA-408 is a novel potent, highly selective and ATP-competitive inhibitor of IKB kinase-2.</p>
    Fórmula:C29H27ClFN7O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:560.02
  • 546C88

    CAS:
    <p>546C88 is an inhibitor of nitric oxide synthase.</p>
    Fórmula:C7H17ClN4O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:224.69
  • STING Agonist 1a

    CAS:
    <p>STING agonist 1a activates STING, induces IRF-SEAP, IFN-β, IL-6, CXCL10 (EC50=16.77 µM); effects reversed by STING KO/inhibitor H-151.</p>
    Fórmula:C19H11Cl2N5O
    Forma y color:Solid
    Peso molecular:396.23
  • Etoricoxib HCl

    CAS:
    <p>Etoricoxib HCl is a synthetic NSAID that inhibits COX-2, blocking prostaglandin production.</p>
    Fórmula:C18H16Cl2N2O2S
    Forma y color:Solid
    Peso molecular:395.30
  • ABD-350

    CAS:
    <p>ABD-350 is ligand-induced inhibitor of nuclear factor kappaB phosphorylation.</p>
    Fórmula:C19H22F2O2
    Forma y color:Solid
    Peso molecular:320.37
  • AI-3

    CAS:
    <p>Nrf2/Keap1 and Keap1/Cul3 interaction inhibitor</p>
    Fórmula:C11H13ClO3S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:292.8
  • Phox-I1

    CAS:
    <p>Phox-I1 is a NOX2 inhibitor targeting the interactive site of p67phox with Rac GTPase.</p>
    Fórmula:C23H19N3O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:401.41
  • (+)-DHMEQ

    CAS:
    (+)-DHMEQ is an antioxidant transcription factor Nrf2 activator. (+)-DHMEQ is the enantiomer of (-)-DHMEQ.
    Fórmula:C13H11NO5
    Forma y color:Solid
    Peso molecular:261.23
  • NCX 466

    CAS:
    <p>cyclooxygenase (COX)-inhibiting nitric oxide (NO) donor</p>
    Fórmula:C20H24N2O9
    Pureza:98%
    Forma y color:Solid
    Peso molecular:436.41
  • COX-2-IN-16

    CAS:
    <p>COX-2-IN-16: potent, selective oral COX-2 blocker, IC50=102 μM, reduces NO, anti-inflammatory.</p>
    Fórmula:C19H12BrN3O2
    Forma y color:Solid
    Peso molecular:394.22
  • hDDAH-1-IN-1 TFA

    CAS:
    <p>hDDAH-1-IN-1 TFA is a selective non-amino acid catalytic site inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) (Ki: 18 μM).</p>
    Fórmula:C12H22F6N4O5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:416.32
  • QD-394

    CAS:
    <p>QD-394 promotes ROS, impairs GSH/GSSG ratio, and is cytotoxic to pancreatic cancer cells, with synergy with napabucasin.</p>
    Fórmula:C19H19N5O2
    Forma y color:Solid
    Peso molecular:349.39
  • Phortress

    CAS:
    <p>Phortress (NSC-710305) is a potent AhR ligand with strong binding affinity, which subsequently triggers the transcription of CYP1A1 and induces antitumor</p>
    Fórmula:C20H25Cl2FN4OS
    Pureza:99.89%
    Forma y color:Solid
    Peso molecular:459.41
  • MHY884

    CAS:
    <p>MHY884 inhibits tyrosinase and UVB-triggered NF-κB activation by reducing oxidative stress.</p>
    Fórmula:C15H14ClNO3S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:323.79
  • NLRP3 antagonist 1

    CAS:
    <p>Potential cancer research drug, NLRP3 antagonist 1, targets immune response in macrophages, neutrophils.</p>
    Fórmula:C16H18N6O
    Forma y color:Solid
    Peso molecular:310.35
  • AHR antagonist 5

    CAS:
    <p>Potent, oral AHR blocker from WO2018195397; IC50 &lt; 0.5μM; hinders tumor growth with anti-PD-1.</p>
    Fórmula:C25H27Cl3FN7
    Pureza:98%
    Forma y color:Solid
    Peso molecular:550.89
  • PC407-ws

    CAS:
    <p>PC407-ws is a water-soluble novel COX-2 inhibitor.</p>
    Fórmula:C24H18F3N3Na2O5S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:563.46
  • Isocyclosporin A

    CAS:
    <p>Isocyclosporin A is a rearranged degradation product. It is formed by acid treatment of cyclosporin A under aqueous and non-aqueous conditions.</p>
    Fórmula:C62H111N11O12
    Forma y color:Solid
    Peso molecular:1202.61
  • ND-2110

    CAS:
    <p>ND-2110, a selective interleukin-1 receptor-associated kinase 4 inhibitors, is used for the treatment of autoimmune disorders and lymphoid malignancy.</p>
    Fórmula:C21H28N4O3S
    Forma y color:Solid
    Peso molecular:416.54
  • Tilarginine

    CAS:
    <p>Tilarginine is a nitric oxide synthetase competitive inhibitor.</p>
    Fórmula:C7H16N4O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:188.23
  • TBK1/IKKε-IN-4

    CAS:
    <p>TBK1/IKKε-IN-4, a 6-aminopyrazolopyrimidine derivative, serves as a potent, selective inhibitor for TBK1 and IKKε, demonstrating IC50 values of 13 nM and 59 nM</p>
    Fórmula:C28H35N7O4
    Forma y color:Solid
    Peso molecular:533.62
  • NRP1 antagonist 2

    CAS:
    <p>NRP1 antagonist 2 (Compound 1) is an NRP1 antagonist.</p>
    Fórmula:C20H17ClN6OS2
    Forma y color:Solid
    Peso molecular:456.97
  • Propoxur

    CAS:
    <p>Propoxur: an insecticide causing temporary cholinergic effects in humans; chronic exposure leads to health issues; carcinogenicity unclassified by EPA.</p>
    Fórmula:C11H15NO3
    Pureza:99.84% - 99.87%
    Forma y color:Minute Crystals (Niosh 2016)
    Peso molecular:209.24
  • Thiazolinobutazone

    CAS:
    <p>Thiazolinobutazone is the 2-amino-2-thiazoline salt of phenylbutazone.</p>
    Fórmula:C22H26N4O2S
    Forma y color:Solid
    Peso molecular:410.53
  • COX/5-LO-IN-1

    CAS:
    <p>COX/5-LO-IN-1 is a cyclooxygenase and 5-lipoxygenase (5-LO) inhibitor, and used for inflammatory and allergic disease states.</p>
    Fórmula:C16H15FN2O2S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:318.37
  • N-α-Tosyl-L-lysine chloromethyl ketone hydrochloride

    CAS:
    <p>N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride inhibits trypsin-like proteases and IFN-γ activities.</p>
    Fórmula:C14H22Cl2N2O3S
    Pureza:97.44%
    Forma y color:Powder
    Peso molecular:369.31
  • COX-2-IN-14

    CAS:
    <p>COX-2-IN-14 (2a) is a potent, selective COX-2 inhibitor with high affinity and notable anti-inflammatory effects in mice.</p>
    Fórmula:C18H18N4O6
    Forma y color:Solid
    Peso molecular:386.364
  • Isonixin

    CAS:
    <p>Isonixin is used for the treatment of inflammation and pain associated with musculoskeletal and joint disorders.</p>
    Fórmula:C14H14N2O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:242.27
  • Bifenazate

    CAS:
    <p>Bifenazate is a positive allosteric modulator of GABA receptor. Bifenazate is an acaricide that controls 100% of mites at a concentration of 25 ppm.</p>
    Fórmula:C17H20N2O3
    Pureza:99.62%
    Forma y color:Solid Crystalline
    Peso molecular:300.35
  • Hetrombopag

    CAS:
    <p>Hetrombopag: potent thrombopoietin receptor agonist, well tolerated, safe, promising for immune thrombocytopenia research.</p>
    Fórmula:C25H22N4O5
    Forma y color:Solid
    Peso molecular:458.47
  • Tenosal

    CAS:
    <p>Tenosal obtained by esterifying salicylic acid with 2-thiophene-carboxylic acid, and with analgesic and antipyretic properties, anti-inflammatory.</p>
    Fórmula:C12H8O4S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:248.25
  • Anti-inflammatory agent 1

    CAS:
    <p>Anti-inflammatory agent 1 is an anti-inflammatory compound.</p>
    Fórmula:C17H16O3S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:300.37
  • Ppc-1

    CAS:
    <p>Ppc-1 inhibits Porphyromonas gingivalis, uncouples mitochondria, and blocks IL-2, with anti-obesity, antibacterial, anti-inflammatory effects.</p>
    Fórmula:C21H25NO4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:355.43
  • Nrf2-Activator-12G

    CAS:
    <p>Nrf2-Activator-12G is a potent Nrf-2 activator.</p>
    Fórmula:C15H13ClO3S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:308.78
  • (-)-Ibuprofenamide

    CAS:
    (-)-Ibuprofenamide is an amide prodrug of Ibuprofen with anti-inflammatory activity.
    Fórmula:C13H19NO
    Pureza:98%
    Forma y color:Solid
    Peso molecular:205.3
  • Carboxyamidotriazole

    CAS:
    <p>Carboxyamidotriazole is a cytostatic inhibitor of non-voltage-operated calcium channels and calcium channel-mediated signaling pathways.</p>
    Fórmula:C17H12Cl3N5O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:424.67
  • MALT1-IN-8

    CAS:
    <p>MALT1-IN-8: potent MALT1 inhibitor, IC50=2 nM; hinders OCI-LY3 cells, IC50=1.16 μM; anticancer, from patent WO2018165385A1.</p>
    Fórmula:C20H15Cl2N7O
    Forma y color:Solid
    Peso molecular:440.29
  • U-83836E

    CAS:
    <p>U-83836E (lazaroid ) Possesses neuroprotective activity and anti-tumor activity, inhibits tumor necrosis factor and reverses endotoxin-induced shock.</p>
    Fórmula:C30H46Cl2N6O2
    Pureza:99.33%
    Forma y color:Solid
    Peso molecular:593.63
  • IL-1β-IN-2

    CAS:
    <p>IL-1β-IN-2, a cannabigerol derivative, serves as a potent inhibitor of IL-1β, exhibiting anti-inflammatory and pain-resolving properties [1].</p>
    Fórmula:C22H34O2
    Forma y color:Solid
    Peso molecular:330.5
  • CHS-111

    CAS:
    <p>CHS-111 is a benzyl indazole that inhibits O2- generation, fMLP-induced PLD activity (IC50 3.9μM), and disrupts PLD1/Arf6 and RhoA interactions.</p>
    Fórmula:C21H18N2O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:314.38
  • NOC-5

    CAS:
    <p>NOC-5 is an NO donor that induces airway relaxation and concentration-dependently triggers 10 μM DAF-2 fluorescence.</p>
    Fórmula:C6H16N4O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:176.22
  • SARS-CoV-2 nsp13-IN-1

    CAS:
    <p>SARS-CoV-2 nsp13-IN-1 (C1) inhibits nsp13 ssDNA+ATPase (IC50: 6 μM), not ssDNA-ATPase; useful for COVID-19 research.</p>
    Fórmula:C27H20N4O2
    Pureza:99.44%
    Forma y color:Solid
    Peso molecular:432.47
  • UC-1V150

    CAS:
    <p>UC-1V150: TLR7 agonist, triggers immune response, anti-tumor, precursor for ISAC synthesis.</p>
    Fórmula:C16H17N5O4
    Forma y color:Solid
    Peso molecular:343.34
  • YS-121

    CAS:
    <p>YS121 inhibits mPGES-1 (IC50=3.4μM) &amp; 5-LOX (IC50=6.5μM), and lowers PGE2 in A549 cells (EC50=12μM).</p>
    Fórmula:C20H26ClN3O2S
    Forma y color:Solid
    Peso molecular:407.96
  • NBC 6

    CAS:
    <p>NLRP3-IN-NBC6: potent NLRP3 inflammasome inhibitor, IC50 574 nM, Ca2+ independent, inhibits inflammasome in THP-1 cells/BMDMs.</p>
    Fórmula:C18H16BCl3N2O2
    Forma y color:Solid
    Peso molecular:409.5
  • STING ligand-1

    CAS:
    <p>STING ligand-1 is a lead STING ligand(IC50 of 68 nM for HAQ STING).</p>
    Fórmula:C29H27ClFNO5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:523.98
  • Anti-inflammatory agent 8

    CAS:
    <p>Anti-inflammatory agent 8 targets COX-2 over COX-1, IC50 of 0.09 nM, orally bioavailable.</p>
    Fórmula:C18H15N5OS2
    Forma y color:Solid
    Peso molecular:381.47
  • iNOS-IN-2

    CAS:
    <p>iNOS-IN-2 (Compound 53) is a potent inducible nitric oxide synthase (iNOS) protein down-regulator.</p>
    Fórmula:C25H31NO7
    Forma y color:Solid
    Peso molecular:457.52
  • NOS1-IN-1

    CAS:
    <p>NOS1-IN-1: selective, potent nNOS inhibitor (Ki: 120 nM), less effective on eNOS/iNOS, for neurological disorder research.</p>
    Fórmula:C14H24F9N7O8
    Pureza:99.7%
    Forma y color:Solid
    Peso molecular:589.37
  • FK-330 dihydrate

    CAS:
    <p>FK-330 dihydrate (FR-260330 dihydrate), as a NOS inhibitor, prevents tissue damage caused by ischemia and reperfusion. Cost-effective and quality-assured.</p>
    Fórmula:C29H32ClF3N6O6
    Pureza:99.52% - 99.98%
    Forma y color:Solid
    Peso molecular:653.05
  • Prostaglandin G/H synthase 1 inhibitor

    CAS:
    <p>Prostaglandin G/H synthase 1 inhibitor (CP 74006) is a selective D5D inhibitor with an IC(50) value of 20 nM.</p>
    Fórmula:C13H11ClN2O
    Pureza:99.76%
    Forma y color:Solid
    Peso molecular:246.69
  • 7-NINA

    CAS:
    non-selective NOS inhibitor
    Fórmula:C7H5N3NaO2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:186.12
  • R110

    CAS:
    <p>R110 shows the potential for cancer research that is a potent, competitive MIF2 tautomerase inhibitor (IC 50 = 15 μM) [1].</p>
    Fórmula:C15H17ClN2OS
    Forma y color:Solid
    Peso molecular:308.83
  • CID-2858522

    CAS:
    <p>CID-2858522 is an effective and specific antigen receptor-mediated NF-κB activation inhibitor (IC50: 70 nM).</p>
    Fórmula:C28H39N3O3
    Pureza:96.12%
    Forma y color:Solid
    Peso molecular:465.63
  • MALT1-IN-3

    CAS:
    <p>MALT1-IN-3 is a potent inhibitor of MALT1 protease (IC50: 0.06 μM) with IC50 values of 0.14 and 0.13 μM for human IL6 and IL10, respectively, in OCI-LY3 cells.</p>
    Fórmula:C21H19F3N8O2
    Forma y color:Solid
    Peso molecular:472.42
  • MK-0703

    CAS:
    <p>MK-0703 is a selective cyclooxygenase-2 inhibitor.</p>
    Fórmula:C17H22O5S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:338.42
  • Insulin levels modulator

    CAS:
    <p>Insulin level regulators can be used to treat diabetes.</p>
    Fórmula:C21H23N7OS
    Pureza:98%
    Forma y color:Solid
    Peso molecular:421.52
  • COX-2/5-LOX-IN-1

    CAS:
    <p>COX-2/5-LOX-IN-1, a benzothiophen-2-yl pyrazole, inhibits COX-2 &amp; 5-LOX with IC50: COX-1 (12.13μM), COX-2 (0.4μM), 5-LOX (4.96μM). Better than Celecoxib.</p>
    Fórmula:C14H10ClN3O4S2
    Forma y color:Solid
    Peso molecular:383.83
  • IKKβ-IN-1

    CAS:
    <p>IKKβ-IN-1 is a potent, orally active inhibitor of IkappaB (IKK-β) (IC50: 0.20 μM).</p>
    Fórmula:C31H30N4O4S
    Forma y color:Solid
    Peso molecular:554.66
  • MIND4-17

    CAS:
    <p>MIND4-17 activates NRF2 by binding Keap1 C151, blocking Keap1-Nrf2, stabilizes Nrf2, and promotes its nuclear entry, with strong antioxidant effects.</p>
    Fórmula:C20H15N5O3S
    Forma y color:Solid
    Peso molecular:405.43
  • IRAK4-IN-21

    CAS:
    <p>IRAK4-IN-21: Oral IRAK4 inhibitor, IC50: IRAK4 5 nM, TAK1 56 nM; curbs IL-23, aids autoimmune research.</p>
    Fórmula:C28H28FN7O2
    Forma y color:Solid
    Peso molecular:513.57
  • MitoB

    CAS:
    <p>MitoB is a novel exon of mitochondrial hydrogen peroxide.</p>
    Fórmula:C25H23BBrO2P
    Forma y color:Solid
    Peso molecular:477.14
  • Heterophdoid A

    CAS:
    <p>Heterophdoid A is an anti-inflammatory agent that inhibits NO production in BV-2 cells (IC50: 5.93 μM).</p>
    Fórmula:C26H42O10
    Forma y color:Solid
    Peso molecular:514.61
  • RWJ 63556

    CAS:
    RWJ 63556 is an orally active inhibitor of COX-2 selective/5-lipoxygenase, shows anti-inflammatory activities.
    Fórmula:C11H10FNO3S2
    Pureza:99.92%
    Forma y color:Solid
    Peso molecular:287.33
  • Nrf2 activator-3

    CAS:
    Nrf2 activator-3 is an Nrf2 activator with potential anti-inflammatory, antioxidant and anti-tumor activity for the study of neurological diseases.
    Fórmula:C23H18F3N3O2
    Pureza:98.52% - 99.84%
    Forma y color:Solid
    Peso molecular:425.4
  • Ruzotolimod

    CAS:
    <p>Ruzotolimod, an agonist of TLR7, exhibits promising potential for investigating HBV, COVID-19, and SARS-CoV-2 infections (WO2021130195A1)[1].</p>
    Fórmula:C14H18N4O5S
    Forma y color:Solid
    Peso molecular:354.38
  • COX-2/15-LOX-IN-1

    CAS:
    <p>COX-2/15-LOX-IN-1 is a dual inhibitor for COX-2/15-LOX with anti-inflammatory properties (IC50: COX-1 10.65μM, COX-2 0.075μM, 15-LOX 2.98μM).</p>
    Fórmula:C21H21N7S3
    Forma y color:Solid
    Peso molecular:467.63
  • Clopirac

    CAS:
    <p>Clopirac is a potent and orally active prostaglandin synthetase inhibitor that is an anti-inflammatory agent [1].</p>
    Fórmula:C14H14ClNO2
    Forma y color:Solid
    Peso molecular:263.72
  • ROS inducer 3

    CAS:
    <p>ROS inducer 3 is a ROS inducer used as a bactericide in the study of resistant plant bacterial diseases, inhibiting Streptomyces.</p>
    Fórmula:C22H22F3N3O
    Pureza:99.88%
    Forma y color:Solid
    Peso molecular:401.43
  • ROS inducer 2

    CAS:
    <p>ROS inducer 2 is a reactive oxygen species (ROS) inducer with antibacterial activity, inhibiting Axonobacter species.</p>
    Fórmula:C23H24F3N3O
    Pureza:99.53% - 99.97%
    Forma y color:Solid
    Peso molecular:415.45
  • NF-κB-IN-2

    CAS:
    <p>NF-κB-IN-2 inhibits canonical NF-κB signaling induced by TNF-α in PC-3 cells.</p>
    Fórmula:C15H18O3
    Forma y color:Solid
    Peso molecular:246.3
  • IND24

    CAS:
    <p>IND24 has anti-prion activity and can be used to study neurodegenerative diseases.</p>
    Fórmula:C21H17N3S
    Pureza:99.64%
    Forma y color:Solid
    Peso molecular:343.44
  • Methyl aminolevulinate

    CAS:
    <p>Methyl aminolevulinate, a prodrug for protoporphyrin IX, sensitizes in PDT.</p>
    Fórmula:C6H11NO3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:145.16