Inmunología e inflamación
Los inhibidores de inmunología e inflamación son compuestos que modulan la respuesta inmunitaria y los procesos inflamatorios. Estos inhibidores son cruciales para estudiar los mecanismos de regulación inmunitaria, la autoinmunidad y la inflamación crónica, así como para desarrollar tratamientos para enfermedades inflamatorias, alergias y trastornos relacionados con el sistema inmunológico. Al dirigirse a vías clave en el sistema inmunológico, estos inhibidores pueden ayudar a reducir las respuestas inmunitarias excesivas o inadecuadas. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad para apoyar su investigación en inmunología, inflamación y desarrollo terapéutico.
Subcategorías de "Inmunología e inflamación"
- CCR(136 productos)
- CXCR(149 productos)
- Pared celular(5 productos)
- Receptor de IL(112 productos)
- IκB / IKK(59 productos)
- LTR(3 productos)
- MALT(23 productos)
- MRP(6 productos)
- NADPH-oxidasa(1 productos)
- NF-κB(443 productos)
- NOD(18 productos)
- NOS(63 productos)
- Nrf2(78 productos)
- PGE sintasa(31 productos)
- ROS(69 productos)
- TGF-beta / Smad(58 productos)
- TLR(66 productos)
- Tiorredoxina(12 productos)
- gp120 / CD4(4 productos)
Mostrar 11 subcategorías más
Se han encontrado 3054 productos de "Inmunología e inflamación"
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CAS:<p>CB-1158 is a potent and orally bioavailable inhibitor of arginase (IC50s: 86 and 296 nM for recombinant human arginase 1 and 2).</p>Fórmula:C11H22BN3O5Pureza:98%Forma y color:SolidPeso molecular:287.12GB1490
CAS:<p>GB1490 is an orally administered galectin inhibitor, demonstrating Kd values of 0.4 μM for galectin-1 and 2.7 μM for galectin-3 [1].</p>Fórmula:C17H15Cl2FN4O4S2Forma y color:SolidPeso molecular:493.36COX-2-IN-7
<p>COX-2-IN-7: potent, orally active COX-2 inhibitor with higher selectivity than Celecoxib, IC50 6.585 uM, anti-inflammatory, low ulcer risk.</p>Fórmula:C15H13N3O2S2Forma y color:SolidPeso molecular:331.41NLRP3-IN-56
CAS:<p>NLRP3-IN-56 (compound 062) is an inhibitor of NLRP3. It effectively suppresses the secretion of IL-1β in THP-1 cells, demonstrating an IC50 of 9.7 nM. NLRP3-IN-56 is useful for research into NLRP3-mediated symptoms and/or diseases.</p>Fórmula:C20H18ClN3O3Forma y color:SolidPeso molecular:383.83meso-Zeaxanthin
CAS:<p>meso-Zeaxanthin accumulates in the central retina and, together with lutein and zeaxanthin, forms the macular pigment, which functions as a light filter. meso-Zeaxanthin can quench reactive oxygen species (ROS), thereby exhibiting antioxidant properties.</p>Fórmula:C40H56O2Forma y color:SolidPeso molecular:568.871XO/COX/LOX-IN-1
<p>XO/COX/LOX-IN-1 targets XO/COX/LOX, used in research of inflammation, cancer, and metabolic disorders.</p>Fórmula:C24H20N4O2SForma y color:SolidPeso molecular:428.51DPP4-In hydrochloride
CAS:<p>DPP4-In (hydrochloride) is an inhibitor of dipeptidyl peptidase 4 (DPP4) that effectively reduces the expression of DPP4.</p>Fórmula:C14H21ClN4O2Forma y color:SolidPeso molecular:312.8oxLig-1
CAS:OxLig-1 (7-Ketocholesteryl-9-carboxynonanoate) constitutes a lipid component of oxidized low-density lipoprotein (oxLDL) and serves as a critical ligand for β-glycoprotein I (β(2)-GPI). It induces nuclear translocation by activating the NF-κB pathway. Additionally, oxLig-1 is utilized in the study of atherosclerosis (AS).Fórmula:C36H58O5Forma y color:SolidPeso molecular:570.84Anti-inflammatory agent 10
<p>Tilomisole-derived benzimidazole-thiazole, orally active, favors COX-2 inhibition over COX-1.</p>Fórmula:C17H13BrN4O3S2Forma y color:SolidPeso molecular:465.34NIK-IN-2
CAS:<p>NIK-IN-2 (compound 1) is an effective inhibitor of NF-κB inducing kinase (NIK), exhibiting a pIC50 of 7.4. It plays a crucial role in cancer research.</p>Fórmula:C20H22N4O3Forma y color:SolidPeso molecular:366.41NLRP3-IN-57
<p>NLRP3-IN-57 (compound 5) inhibits the NLRP3 inflammasome, consequently downregulating IL-1β levels in THP-1 macrophages induced by LPS+Nigericin.</p>Fórmula:C44H60O7Forma y color:SolidPeso molecular:700.94Indeno[1,2,3-cd]pyrene
CAS:<p>Indeno[1,2,3-cd]pyrene, a polycyclic aromatic hydrocarbon, exhibits moderate cytotoxicity to human alveolar epithelial cells (HPAEpiC). Additionally, it enhances allergic pulmonary inflammation responses through the activation of the aryl hydrocarbon receptor.</p>Fórmula:C22H12Forma y color:SolidPeso molecular:276.33Zharp1-211
CAS:<p>Zharp1-211 is a RIPK3 inhibitor，reduces JAK/ stat1-mediated chemokines and MHC class II molecules in IECs, (GVHD) for gastrointestinal inflammation.</p>Fórmula:C24H25N5O4Pureza:99.71%Forma y color:SolidPeso molecular:447.49HOIPIN-8 sodium
CAS:<p>HOIPIN-8 sodium is a LUBAC inhibitor for the study of inflammatory and immune diseases.</p>Fórmula:C23H15F2N4NaO3Pureza:97.34%Forma y color:SolidPeso molecular:456.38UBS109
CAS:<p>UBS109, a curcumin analog, is a DNA demethylating agent in pancreatic cancer that promotes osteoblast differentiation and mineralization.</p>Fórmula:C18H17N3OPureza:99.48%Forma y color:SolidPeso molecular:291.35KI696
CAS:<p>KI696 is a high-affinity probe that potently inhibits the interaction of Keap1 and NRF2.</p>Fórmula:C28H30N4O6SPureza:99.74%Forma y color:SolidPeso molecular:550.63AM103
CAS:<p>AM103 is an effective and selective inhibitor of FLAP (IC50 = 4.2 nM).</p>Fórmula:C36H38N3NaO4SPureza:99.75%Forma y color:SolidPeso molecular:631.76VVD-130037
CAS:VVD-130037 is a KEAP1 activator with potential antitumor activity.VVD-130037 inhibits tumor growth in advanced solid tumors by degrading NRF2.Fórmula:C17H17ClN4O2Pureza:99.01% - 99.92%Forma y color:SolidPeso molecular:344.8Antiproliferative agent-22
CAS:<p>Antiproliferative agent-22 is an anticancer compound that shows antiproliferative activity on MCF-7, MDA-MB-231 and MDA-MB-468 cells.</p>Fórmula:C17H13N3O3Pureza:99.20% - 99.27%Forma y color:SolidPeso molecular:307.3Evixapodlin
CAS:<p>Evixapodlin (PD-1/PD-L1-IN 7) is a human PD-1/PD-L1 protein/protein interaction inhibitor (IC50: 0.213).Evixapodlin has anticancer and antiviral activities.</p>Fórmula:C34H36Cl2N8O4Pureza:99.07%Forma y color:SolidPeso molecular:691.61Dazostinag disodium
CAS:<p>Dazostinag disodium (TAK-676) is a synthetic novel interferon gene (STING) agonist.Cost-effective and quality-assured.</p>Fórmula:C21H20F2N8Na2O10P2S2Pureza:98.84% - 99.96%Forma y color:SolidPeso molecular:754.482-Selenouracil
CAS:<p>2-Selenouracil is a specialized photosensitizer for photodynamical therapy.</p>Fórmula:C4H4N2OSeForma y color:SolidPeso molecular:175.05NSC23925
CAS:NSC23925 is a selective and effective inhibitor of P-glycoprotein (Pgp).Fórmula:C22H26Cl2N2O2Pureza:98%Forma y color:SolidPeso molecular:421.36Veledimex
CAS:<p>Veledimex is an oral activator ligand for a proprietary gene therapy promoter system. It is also a moderate inhibitor of and substrate for CYP3A4/5.</p>Fórmula:C27H38N2O3Pureza:98%Forma y color:SolidPeso molecular:438.6PSB-12379
CAS:<p>PSB-12379 is a potent inhibitor of Ecto-5'-Nucleotidase (CD73)(Kis of 9.03 nM (rat) and 2.21 nM (human)).</p>Fórmula:C18H23N5O9P2Pureza:98%Forma y color:SolidPeso molecular:515.35α-Terpineol
CAS:<p>Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol (Terpineol) shows anticonvulsant, and anti-inflammatory activities, it inhibits the gene expression of the IL-6 receptor.</p>Fórmula:C10H18OPureza:97.55%Forma y color:Colorless LiquidPeso molecular:154.2511β,17α,21-Trihydroxypregna-1,4-diene-3,20-dione
CAS:Fórmula:C21H28O5Pureza:98%Forma y color:SolidPeso molecular:360.4440Ref: IN-DA0034OW
Producto descatalogado9a-Fluoro-11b,17a,21-trihydroxy-16b-methylpregna-1,4-diene-3,20-dione
CAS:Fórmula:C22H29FO5Pureza:99%Forma y color:SolidPeso molecular:392.4611Ref: IN-DA0034IN
Producto descatalogado11β,17α,21-Trihydroxypregn-4-ene-3,20-dione
CAS:Fórmula:C21H30O5Pureza:98%Forma y color:SolidPeso molecular:362.4599Ref: IN-DA003AAY
Producto descatalogado(11β,16α)-9-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
CAS:Fórmula:C24H31FO6Pureza:99%Forma y color:SolidPeso molecular:434.4977Ref: IN-DA0039HQ
Producto descatalogadoTripeptide-41
CAS:<p>Tripeptide-41 (CG-Lipoxyn) is a bioactive peptide known for its ability to reduce fat accumulation.</p>Fórmula:C29H30N4O5Pureza:98%Forma y color:SolidPeso molecular:514.57Tacalcitol
CAS:<p>Tacalcitol (1,24(R)-Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3) promotes normal bone development by regulating calcium and modulates immunological and inflammatory processes.</p>Fórmula:C27H44O3Pureza:98%Forma y color:SolidPeso molecular:416.64JH-X-119-01 hydrochloride
CAS:<p>JH-X-119-01 hydrochloride is a potent, selective inhibitor of interleukin-1 receptor-associated kinase 1 (IRAK1) that effectively alleviates lipopolysaccharide (LPS)-induced sepsis in mice.</p>Fórmula:C25H21ClN6O3Forma y color:SolidPeso molecular:488.93STING agonist-22
CAS:<p>STING agonist-22 (CF501) boosts vaccines by activating STING, inducing IFN-I and cytokines, aiding in SARS-CoV-2 research.</p>Fórmula:C40H48N14O6Forma y color:SolidPeso molecular:820.9Magnesium citrate
CAS:<p>Magnesium citrate is a useful organic compound for research related to life sciences. The catalog number is T64455 and the CAS number is 3344-18-1.</p>Fórmula:C12H10Mg3O14Forma y color:SolidPeso molecular:451.113Icatolimab
<p>Icatolimab (JS-004) is a humanized antibody targeting BTLA/CD272 for the study of lymphomas and solid tumors.</p>Pureza:98.7% (SDS-PAGE); 95.6% (SEC-HPLC) - 98.7% (SDS-PAGE); 95.6% (SEC-HPLC)Forma y color:LiquidPeso molecular:145.5 kDaRef: TM-T77490
Producto descatalogadoRacemic Naproxen
CAS:<p>Racemic Naproxen is a biochemical substance.</p>Fórmula:C14H14O3Pureza:98%Forma y color:Crystals From Acetone-Hexane White SolidPeso molecular:230.26TLQP-21 TFA
<p>TLQP-21 TFA is a VGF-derived peptide, C3aR1 agonist (mouse EC50: 10.3μM; human EC50: 68.8μM), that raises intracellular Ca2+ for nociception research.</p>Pureza:98%Forma y color:LiquidXibornol
CAS:<p>Xibornol (Nanbacine) 具有广谱的抗菌和抗病毒活性，可用于研究革兰氏阳性菌感染和人呼吸道合胞病毒与人冠状病毒229E感染。</p>Fórmula:C18H26OForma y color:SolidPeso molecular:258.4Aurothioglucose
CAS:<p>Aurothioglucose is a active-site TrxR1 inhibitor.</p>Fórmula:C6H11AuO5SPureza:98%Forma y color:Yellow Crystals SolidPeso molecular:392.18Pam2CSK4 TFA
<p>Pam2CSK4 TFA (PUL-042 TFA) is a potent dual agonist of TLR2 and TLR6, a peptide that mimics bacterial lipoproteins.Pam2CSK4 TFA promotes platelet aggregation, and can be used to study the effects of lipoproteins on the periodontium.</p>Fórmula:C67H127F3N10O14SPureza:99.90%Forma y color:SoildPeso molecular:1385.84Di-O-methyldemethoxycurcumin
CAS:<p>Di-O-methyldemethoxycurcumin is a Curcumin analog isolated from medicinal plant turmeric di-orthomethyldemethoxycurcumin, anti-inflammatory and antioxidant properties Inhibition of IL-6 production, EC50 is 16.20μg/mL.</p>Fórmula:C22H22O5Pureza:98%Forma y color:SolidPeso molecular:366.41TLR7/8/9 antagonist 2
CAS:<p>TLR7/8/9 antagonist 2 is an orally active and highly bioavailable vTLR7/8/9 antagonist. It inhibits HEK/hTLR7, HEK/hTLR8, and HEK/hTLR9 with IC50s of 0.011 μM, 0.029 μM, and 0.052 μM, respectively. TLR7/8/9 antagonist 2 can be used to study auto-inflammatory diseases such as systemic lupus erythematosus or lupus nephritis.</p>Fórmula:C23H31N7Pureza:98%Forma y color:SoildPeso molecular:405.54Elamipretide acetate
<p>Elamipretide acetate (MTP 131), a small tetrapeptide, targets mitochondria to reduce toxic species and stabilize cardiolipin.</p>Fórmula:C34H53N9O7Pureza:99.76%Forma y color:SoildPeso molecular:699.84RIDR-PI-103
CAS:<p>RIDR-PI-103 is a reactive oxygen species (ROS)-induced drug release prodrug featuring an autocyclized portion connected to the pan-PI3K inhibitor (PI-103). In MDA-MB-361 and MDA-MB-231 cells, Doxorubicin and RIDR-PI-103 exhibited synergistic inhibition of cancer cell proliferation.</p>Fórmula:C27H25N7O4Forma y color:SolidPeso molecular:511.53TLQP-21 TFA
<p>TLQP-21 TFA （TLQP-21 Trifluoroacetate） 是一种 VGF 衍生肽，可通过结合后折叠机制激活C3aR1 受体。</p>Pureza:98%gp91ds-tat
<p>gp91ds-tat is a useful organic compound for research related to life sciences and the catalog number is T35393.</p>Pureza:98%Forma y color:Solid2,3-Bis(3-indolylmethyl)indole
CAS:<p>2,3-Bis(3-indolylmethyl)indole exhibits a concentration-dependent inhibition of RANKL-induced osteoclastogenesis, actin ring formation, and bone resorption.</p>Fórmula:C26H21N3Forma y color:SolidPeso molecular:375.475ARGX-112
CAS:<p>Temtokibart is a humanized IgG1 λ2 antibody that specifically targets IL22RA1, and is expressed by cells that are deficient in the glutamine synthetase gene.</p>Forma y color:Odour LiquidL-NIO dihydrochloride
CAS:<p>L-NIO dihydrochloride, a potent and non-selective NADPH-dependent nitric oxide synthase (NOS) inhibitor, consistently induces focal ischemic infarct in rats. It exhibits inhibitory constants (Kis) of 1.7, 3.9, and 3.9 μM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS) forms, respectively.</p>Fórmula:C7H16ClN3O2Pureza:98%Forma y color:SolidPeso molecular:209.67ALPK1-IN-2
CAS:<p>ALPK1-IN-2 is a potent inhibitor of ALPK1 (α-kinase 1) (IC50: 95 nM). ALPK1-IN-2 inhibits NF-κB (IC50: 1.31 μM).</p>Fórmula:C20H18F2N4O2SForma y color:SolidPeso molecular:416.44Ref: TM-T62162
Producto descatalogadoALPK1-IN-1
CAS:<p>ALPK1-IN-1 (A001) strongly inhibits ALPK1, key for innate immunity & NF-κB signaling via TIFA/TRAF.</p>Fórmula:C25H32N6O2SForma y color:SolidPeso molecular:480.63ALPK1-IN-3
CAS:<p>ALPK1-IN-3,serves as an ALPK1 inhibitor that dampens proinflammatory gene expression in the kidney and enhances survival in animal models of sepsis-induced</p>Fórmula:C20H16F2N4OSPureza:98%Forma y color:SolidPeso molecular:398.43
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