Inmunología e inflamación
Los inhibidores de inmunología e inflamación son compuestos que modulan la respuesta inmunitaria y los procesos inflamatorios. Estos inhibidores son cruciales para estudiar los mecanismos de regulación inmunitaria, la autoinmunidad y la inflamación crónica, así como para desarrollar tratamientos para enfermedades inflamatorias, alergias y trastornos relacionados con el sistema inmunológico. Al dirigirse a vías clave en el sistema inmunológico, estos inhibidores pueden ayudar a reducir las respuestas inmunitarias excesivas o inadecuadas. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad para apoyar su investigación en inmunología, inflamación y desarrollo terapéutico.
Subcategorías de "Inmunología e inflamación"
- CCR(136 productos)
- CXCR(148 productos)
- Pared celular(5 productos)
- Receptor de IL(112 productos)
- IκB / IKK(60 productos)
- LTR(3 productos)
- MALT(23 productos)
- MRP(6 productos)
- NADPH-oxidasa(1 productos)
- NF-κB(444 productos)
- NOD(17 productos)
- NOS(63 productos)
- Nrf2(79 productos)
- PGE sintasa(31 productos)
- ROS(69 productos)
- TGF-beta / Smad(58 productos)
- TLR(66 productos)
- Tiorredoxina(12 productos)
- gp120 / CD4(4 productos)
Mostrar 11 subcategorías más
Se han encontrado 3045 productos de "Inmunología e inflamación"
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NBD peptide
CAS:<p>NBD peptide inhibits the NF-κB signaling pathway by preventing the binding of the NEMO-IKK complex. It exhibits anti-inflammatory activity by blocking the production of pro-inflammatory cytokines. Additionally, NBD peptide demonstrates immunosuppressive effects through the regulation of immune cells. It enhances transmembrane capacity by conjugating with the cell-penetrating peptide HIV-TAT.</p>Fórmula:C62H88N14O20Forma y color:SolidPeso molecular:1349.44STING modulator-5
CAS:<p>STING modulator-5: pIC50 9.5, antagonizes PBMC (pIC50 8.1), THP-1 cell antagonist, for immunology research.</p>Fórmula:C43H45F4N11O5Forma y color:SolidPeso molecular:871.88ARC186
<p>ARC186 is a highly potent aptamer that serves as a complement inhibitor by blocking the convertase-catalyzed activation of C5.</p>Forma y color:SolidPeso molecular:120702.76XJB-5-131
CAS:<p>XJB-5-131: synthetic, bi-functional antioxidant; targets mitochondria, scavenges ROS/electrons, protects CB MNCs from irradiation.</p>Fórmula:C53H80N7O9Forma y color:SolidPeso molecular:959.26312-Oxo phytodienoic acid
CAS:<p>12-oxo PDA boosts alkaloid production in E. californica, enhances B. dioica tendril curls, and blocks JA-induced cell death in A. fru mutants.</p>Fórmula:C18H28O3Pureza:98%Forma y color:SolidPeso molecular:292.41(R)-Zadavotide guraxetan
CAS:<p>Zadavotide guraxetan (PSMAI&T; PNT-2002) is an inhibitor of prostate-specific membrane antigen (PSMA) with potential antitumor activity, and it is useful for research targeting prostate cancer.</p>Fórmula:C63H92IN11O23Forma y color:SolidPeso molecular:1498.37Polyinosinic acid sodium
CAS:<p>Polyinosinic Acid Sodium, the sodium variant of Polyinosinic Acid, is a single-stranded homonucleic acid that acts as a Toll-like Receptor 3 (TLR3) ligand. By engaging TLR3 and TRIF, it bolsters cellular immune response, showing promise for immune regulation applications [1].</p>Fórmula:(C10H13N4O8P)x·xNaForma y color:SolidRipertamab
CAS:<p>Ripertamab (SCT-400) is a recombinant human-mouse chimeric monoclonal antibody that targets CD20 and is cytotoxic.</p>Pureza:97.8% (SEC-HPLC) - 97.8% (SEC-HPLC)Forma y color:LiquidClivatuzumab
CAS:<p>Clivatuzumab is a humanized anti-myxinomab, which can target the MUC1 epitope highly expressed on the surface of most pancreatic cancer cells, and has a good</p>Pureza:SDS-PAGE:95% SEC-HPLC:99.99%Forma y color:LiquidPeso molecular:145.42 kDaEritoran
CAS:<p>Eritoran: TLR4 antagonist; shields mice from lethal influenza, EBOV, MARV; reduces granulocytosis, eases cytokine storm.</p>Fórmula:C66H126N2O19P2Forma y color:SolidPeso molecular:1313.663-Methoxycatechol
CAS:<p>3-Methoxycatechol: lignin-based, esophageal carcinogen. 1,2-Dihydroxy-3-methoxybenzene: potent anti-EMCV.</p>Fórmula:C7H8O3Pureza:99.31%Forma y color:SolidPeso molecular:140.14Chitohexaose hexahydrochloride
CAS:<p>Chitohexaose hexahydrochloride, a TLR4-inhibiting chitosan derivative, blocks LPS-induced inflammation.</p>Fórmula:C36H74Cl6N6O25Forma y color:SolidPeso molecular:1203.71Biotin-labeled ODN 2395 sodium
<p>Biotin-labeled ODN 2395 (sodium), a Class C oligodeoxynucleotide and TLR9 agonist, serves to assess cellular uptake and localization of CpG ODN through a biotin</p>Forma y color:Odour SolidAra-F-NAD+
CAS:<p>Ara-F-NAD+, an arabino analogue of NAD + , is a potent, slow-binding CD38 NADase inhibitor, with a K i of 169 nM.</p>Fórmula:C21H26FN7O13P2Forma y color:SolidPeso molecular:665.421Maritimetin
CAS:<p>Maritimein, an aurone from Coreopsis tinctoria, has potent antioxidant activity (IC50: 4.12 μM) and is used in cardiovascular research.</p>Fórmula:C15H10O6Forma y color:SolidPeso molecular:286.24NH2-UAMC1110 TFA
CAS:<p>NH2-UAMC1110 TFA, a derivative of the fibroblast activation protein (FAP) inhibitor UAMC1110, serves as a precursor in the formation of FAPI-QS, a chelating</p>Fórmula:C23H24F5N5O5Pureza:99.02%Forma y color:SolidPeso molecular:545.46Anti-CD200R1 Antibody
<p>Anti-CD200R1 Antibody is an antibody that targets CD200R1 and can be used to study protein immunoblotting.</p>Pureza:97.9% (SDS-PAGE); 98.6% (SEC-HPLC) - 97.9% (SDS-PAGE); 98.6% (SEC-HPLC)Forma y color:Odour LiquidCQ-16
CAS:<p>CQ-16 is an orally active small molecule drug conjugate (SMDC) that targets prostate-specific membrane antigen (PSMA). It exhibits high selectivity in its antiproliferative activity between PSMA-positive and PSMA-negative prostate cells. Additionally, CQ-16 possesses PARP inhibitory activity (IC50=1 nM).</p>Fórmula:C40H47FN8O12Forma y color:SolidPeso molecular:850.85Ibritumomab
<p>Ibritumomab is a murine-derived anti-CD20 monoclonal antibody that kills tumor cells by forming free radicals in target cells and surrounding tissues.</p>Pureza:96% (SDS-PAGE); 95.9% (SEC-HPLC) - 96% (SDS-PAGE); 95.9% (SEC-HPLC)Forma y color:Odour LiquidTMV-IN-6
<p>TMV-IN-6 (Compound 4g) serves as a novel antiviral and fungicidal agent that impedes tobacco mosaic virus (TMV) assembly, functioning by attachment to TMV coat</p>Fórmula:C29H27N3OSForma y color:SolidPeso molecular:465.61Coltuximab
<p>Coltuximab is a humanized anti-CD19 antibody that can be used to synthesize ADC compounds (Coltuximab Ravtansine).</p>Pureza:95.3% (SDS-PAGE); 98.6% (SEC-HPLC) - 95.3% (SDS-PAGE); 98.6% (SEC-HPLC)Forma y color:Odour LiquidKeap1-Nrf2-IN-9
CAS:<p>Keap1-Nrf2-IN-9 inhibits Keap1-Nrf2 PPI with 0.575 µM IC50, boosts Nrf2 genes, non-toxic in ARPE19 cells.</p>Fórmula:C31H30N2O11S2Forma y color:SolidPeso molecular:670.71CLIP (86-100)
CAS:<p>Amino acids 86-100 of CLIP, replaced by DM to allow MHC class II to present foreign peptides, triggering immune response.</p>Fórmula:C72H128N20O19S3Pureza:98%Forma y color:SolidPeso molecular:1674.14-methyl-6-phenyl-2H-pyranone
CAS:<p>4-methyl-6-phenyl-2H-pyranone from Scutellaria boosts mitochondria, shields astrocytes from peroxide.</p>Fórmula:C12H10O2Pureza:>99.99%Forma y color:SolidPeso molecular:186.21Biotinoyl tripeptide-1
CAS:<p>Biotinoyl tripeptide-1 can produce hair follicles by promoting scalp micro-circulation and reduce follicle atrophy and aging.</p>Fórmula:C24H38N8O6SPureza:98%Forma y color:SolidPeso molecular:566.67TH023
<p>TH023 is an inhibitor of the TLR4 signaling pathway, specifically targeting the formation of TLR4 homodimers. In HEK-Blue hTLR4 cells, TH023 suppresses the secretion of embryonic alkaline phosphatase with an IC50 of 0.354 μM and inhibits NO expression in RAW264.7 cells, with an IC50 of 1.61 μM. Additionally, TH023 inhibits the activation of NF-κB and reduces the nuclear translocation of NF-κB p65. The compound demonstrates anti-inflammatory effects in a mouse model of LPS-induced acute sepsis and improves lung injury in mice.</p>Fórmula:C22H21ClF2N4OForma y color:SolidPeso molecular:430.88STING agonist-8 dihydrochloride
<p>STING Agonist-8 Dihydrochloride (Compound 5-AB) is a highly effective STING agonist, exhibiting an EC50 value of 27 nM in THP1-Dual KI-hSTING-R232 cells.</p>Fórmula:C41H48Cl2N14O4Forma y color:SolidPeso molecular:871.82G3-C12
CAS:<p>G3-C12 shows anticancer activity. is a galectin-3 binding peptide, with Kd of 88 nM.</p>Fórmula:C74H115N23O23S2Pureza:98%Forma y color:SolidPeso molecular:1758.99LL-37 GKE acetate
<p>LL-37 GKE acetate, a peptide and active structural domain of LL-37, inhibits lps-induced vascular nitric oxide production,less toxic,antimicrobial，sepsis.</p>Fórmula:C121H206N38O30Pureza:99.88%Forma y color:SolidPeso molecular:2673.17FITC-labeled ODN 1668 sodium
<p>FITC-labeled ODN 1668 (sodium), a class B CpG oligodeoxynucleotide (ODN), functions as a TLR9 agonist.</p>Forma y color:Odour SolidBivalirudin TFA
CAS:<p>Bivalirudin TFA, a 20-residue synthetic peptide, reversibly inhibits thrombin, affecting platelet aggregation and thrombin generation.</p>Fórmula:C98H138N24O33·C2HF3O2Forma y color:SolidPeso molecular:2294.34STING ligand-2
CAS:<p>STING ligand-2 serves as a ligand for STING and can be utilized as the target protein ligand in the synthesis of the PROTAC degrader STING-IN-10.</p>Fórmula:C13H12N2O5Forma y color:SolidPeso molecular:276.25Hydroxychloroquine Impurity E
CAS:<p>Hydroxychloroquine Impurity E, a byproduct, can block TLR7/9 and inhibit SARS-CoV-2 in vitro.</p>Fórmula:C14H17ClN2OForma y color:SolidPeso molecular:264.75BMS-986235
CAS:<p>BMS-986235 (LAR-1219), an oral FPR2 agonist, EC50: 0.41 nM (hFPR2), 3.4 nM (mFPR2), may prevent heart failure.</p>Fórmula:C18H17F2N3O3Pureza:99.85%Forma y color:SolidPeso molecular:361.343-Hydroxykynurenamine
CAS:<p>3-Hydroxykynurenamine (3-HKA) is a tryptophan metabolite with anti-inflammatory effects, reducing cytokines and aiding in models of psoriasis and nephritis.</p>Fórmula:C9H12N2O2Forma y color:SolidPeso molecular:180.2Nrf2 activator-8
<p>Nrf2 Activator-8 (Compound 10e), with an EC50 of 37.9 nM, is a potent Nrf2 activator that demonstrates significant antioxidant and anti-inflammatory properties</p>Fórmula:C13H11ClN2O3SForma y color:SolidPeso molecular:310.76TLR8 agonist 7
CAS:<p>TLR8 agonist7 is an agonist of Toll-like receptor 8 (TLR8) with an EC50 of less than 250 nM. It remains stable in human and mouse plasma and induces the secretion of the cytokine TNFα with an EC50 of less than 1 μM. In the MC38-HER2 xenograft mouse model, TLR8 agonist7 demonstrates antitumor activity, achieving a tumor growth inhibition (TGI) rate of 98%.</p>Fórmula:C54H63N9O16Forma y color:SolidPeso molecular:1094.13EPI-589
CAS:<p>EPI-589, a quinone oxidoreductase inhibitor, may treat ALS; it's safe and tolerable.</p>Fórmula:C14H19NO4Pureza:98%Forma y color:SolidPeso molecular:265.31Biotin-labeled ODN 1826 sodium
<p>Biotin-labeled ODN 1826 (sodium), a class B CpG oligodeoxynucleotide (ODN), serves as a TLR9 agonist and facilitates assessment of CpG ODN cellular uptake and</p>Forma y color:Odour SolidDalutrafusp alfa
CAS:<p>Dalutrafusp alfa (AGEN-1423; GS-1423) is a bifunctional antibody targeting CD73 and TGF-β, components of the immunosuppressive pathway [1].</p>Forma y color:Liquid2-Hydroxybenzylamine
CAS:<p>2-Hydroxybenzylamine captures IsoLGs, prevents early atrial fibrillation recurrence post-ablation.</p>Fórmula:C7H9NOPureza:95.93%Forma y color:CoaPeso molecular:123.15Mipeginterferon alfa-2b
CAS:<p>Mipeginterferon alfa-2b, an IFNA2b analogue, has 5 modified amino groups out of 11 and weighs 40 kDa.</p>Forma y color:LiquidTuparstobart
CAS:<p>Tuparstobart (Incagn-02385) is an IgG1κ monoclonal antibody that targets the immune checkpoint receptor protein LAG-3, which is predominantly expressed on</p>Forma y color:LiquidBengamide B
CAS:<p>Potent NF-κB inhibitor, IC50 at 85 nM. Reduces IκBα phosphorylation, NO, TNF-α, IL-6, MCP. Inhibits HeLa, HCT116 cell growth. Anti-inflammatory, antitumor.</p>Fórmula:C32H58N2O8Forma y color:SolidPeso molecular:598.81Cugrastomig
<p>Cugrastomig is a chimeric antibody of human and humanized IgG1κ-[scFv-heavy -κ]2 type, targeting PDCD1/LAG3.</p>Forma y color:Odour LiquidKeap1-Nrf2-IN-27
<p>Keap1-Nrf2-IN-27 is an inhibitor of the Keap1-Nrf2 protein-protein interaction (PPI) with a KD2 value of 0.119 μM. It suppresses the expression of pro-inflammatory cytokines TNF-α and IL-6 in an LPS-induced RAW264.7 cell model.</p>Forma y color:Odour SolidSalicortin
CAS:<p>Salicortin, a phenolic glycoside from Populus and Salix, has anti-adipogenic, anti-amnesic, and immune effects.</p>Fórmula:C20H24O10Pureza:98%Forma y color:SolidPeso molecular:424.40ODN D-SL03
CAS:<p>ODN D-SL03, a C class CpG oligonucleotide, stimulates PBMCs, activating B cells, NK cells & monocytes, and can inhibit tumor growth.</p>Forma y color:SolidPeso molecular:9345SARS-CoV-2-IN-39
CAS:<p>SARS-CoV-2-IN-39 is a SARS-CoV-2 inhibitor with an EC50 of 1 μM.</p>Fórmula:C14H8ClF4NO3Pureza:99.86%Forma y color:SoildPeso molecular:349.66Gliotoxin
CAS:<p>Gliotoxin, a mycotoxin, inhibits Wnt pathway, causing apoptosis in mutated colorectal cancer cells and blocks NF-κB by preserving IκB.</p>Fórmula:C13H14N2O4S2Pureza:98%Forma y color:SolidPeso molecular:326.39Gp100 (25-33), human
CAS:<p>Gp100 (25-33), human: 9-AA melanoma antigen fragment, H-2Db restricted, T-cell recognized, targets B16 melanoma.</p>Fórmula:C52H82N16O14Pureza:98%Forma y color:SolidPeso molecular:1155.31Calcitriol Impurities D
CAS:<p>Calcitriol Impurities D: Vitamin hormone, promotes cell differentiation, has bone activity, inhibits HIV, and aids in treating AIDS/viral infections.</p>Fórmula:C28H46O3Pureza:98%Forma y color:SolidPeso molecular:430.66CP-447697
CAS:<p>CP-447697, a lipophilic C5a receptor antagonist, exhibits an IC50 of 31 nM. It is utilized in inflammation research.</p>Fórmula:C29H26ClF2N3O2SPureza:99.90%Forma y color:SoildPeso molecular:554.05Ulevostinag
CAS:<p>Ulevostinag (MK-1454) is a STING agonist.</p>Fórmula:C20H22F2N10O9P2S2Forma y color:SolidPeso molecular:710.52Cryogenine
CAS:<p>Cryogenine, from H. salicifolia, is an anti-inflammatory alkaloid, blocks prostaglandin synthetase, and alleviates rat arthritis.</p>Fórmula:C26H29NO5Forma y color:SolidPeso molecular:435.52Corza6
<p>Corza6 is a potent and selective peptide inhibitor of the human voltage-gated proton channel (hHv1). It binds to the external voltage sensor domain (VSD) loop in hHv1 at a resting membrane potential (RMP) of natural hyperpolarization in mammalian cells with a Kd of approximately 1 nM. Corza6 facilitates sperm capacitation and permits sustained production of reactive oxygen species (ROS) in leukocytes (WBC).</p>Fórmula:C203H293N55O61S7Forma y color:SolidPeso molecular:4704.29Glutaminase C-IN-2
<p>Glutaminase C-IN-2 (compound 11), an allosteric inhibitor of glutaminase C (GAC), exhibits potent inhibitory activity with an IC50 of 10.64 nM.</p>Fórmula:C24H23N7O2SPureza:98%Forma y color:SolidPeso molecular:473.55PROTAC IRAK4 degrader-4
CAS:<p>PROTAC IRAK4 degrader-4 is a targeted Cereblon-based molecule for degrading IRAK4.</p>Fórmula:C41H38F3N11O10Forma y color:SolidPeso molecular:901.817Ezeprogind
CAS:<p>Ezeprogind, TLR9 inhibitor for Alzheimer's. Affordable Excellence: Reliable Quality You Can Trust</p>Fórmula:C25H44N6Pureza:99.28%Forma y color:SolidPeso molecular:428.66OVA Peptide(257-264) TFA
CAS:<p>OVA Peptide (257-264) TFA, an octameric peptide epitope from ovalbumin, is presented by the class I MHC molecule, H-2Kb, showcasing a class I (Kb)-restricted</p>Fórmula:C47H75F3N10O15Pureza:98%Forma y color:SolidPeso molecular:1077.15Ieramilimab
<p>Ieramilimab (LAG525) is a humanized antibody targeting LAG-3 with potential anticancer activity for the study of malignant tumors.</p>Pureza:96.4% (SDS-PAGE); 97.8% (SEC-HPLC) - 96.4% (SDS-PAGE); 97.8% (SEC-HPLC)Forma y color:Odour LiquidPROTAC IRAK4 degrader-5
CAS:<p>PROTAC IRAK4 degrader-5 is a Cereblon-based IRAK4 degrader.</p>Fórmula:C41H40F3N11O9Forma y color:SolidPeso molecular:887.834UNC8900
<p>UNC8900 is a VHL-recruiting STINGPROTAC degrader with a DC50 of 0.924 μM. It is applicable for the study of bacterial and viral infections.</p>Fórmula:C75H99N17O15SPeso molecular:1509.72273CAY10512
CAS:<p>CAY10512, a resveratrol analog, is 100x more potent, inhibiting NF-κB with an IC50 of 0.15 μM versus resveratrol's 20 μM.</p>Fórmula:C15H13FOForma y color:SolidPeso molecular:228.266N-decanoyl-L-Homoserine lactone
CAS:<p>C10-HSL, an AHL from Pseudomonas cremoris ND07, stunts Arabidopsis roots by raising Ca2+, ROS, MPK6 activity, and NO levels.</p>Fórmula:C14H25NO3Pureza:99.81%Forma y color:SolidPeso molecular:255.35Antidesmone
CAS:<p>Antidesmone from Ajuga decumbens inhibits acute lung injury by modulating MAPK and NF-κB.</p>Fórmula:C19H29NO3Pureza:98%Forma y color:SolidPeso molecular:319.44PROTAC IRAK4 ligand-4
CAS:<p>PROTAC IRAK4 ligand-4, a Ligand for Target Protein for PROTAC (Ligand for Target Protein for PROTAC), exhibits anti-tumor activity and is utilized in synthesizing PROTAC IRAK4 degrader-12. This compound serves as a targeted ligand with specific applications in the development of cancer therapeutics.</p>Fórmula:C24H26F2N6O3Forma y color:SolidPeso molecular:484.5Alcestobart
<p>Alcestobart is a humanized IgG4κ monoclonal antibody targeting LAG3, with HumanIgG4(S228P) kappa serving as its isotype control.</p>Forma y color:Odour LiquidBenz-AP
CAS:<p>Benz-AP: potent photosensitizer, creates singlet oxygen, more toxic in low hCES2 cancer cells, generates ROS via TPE to kill tumors.</p>Fórmula:C20H13NO2Forma y color:SolidPeso molecular:299.32(±)19(20)-EDP Ethanolamide
CAS:<p>(±)19(20)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 108 and 280 nM for CB1 and CB2, respectively).</p>Fórmula:C24H37NO3Forma y color:SolidPeso molecular:387.564α-Guanidinoglutaric Acid
CAS:<p>α-Guanidinoglutaric Acid is found in cobalt-induced epileptogenic focus tissue in the cerebral cortex of cats.</p>Fórmula:C6H11N3O4Pureza:99.73%Forma y color:SolidPeso molecular:189.17TLR4-IN-C34-C2-amide-C6-OH
<p>TLR4-IN-C34-C2-amide-C6-OH: a linker with TLR4-IN-C34 that curbs TLR4 and inflammation in mice.</p>Fórmula:C25H42N2O11Forma y color:SolidPeso molecular:546.61Maresin 2
CAS:<p>Maresin 2 (3R,14S-diHDHA) is a specialized pro-ablative lipid mediator with anti-inflammatory and analgesic activity that promotes mucosal repair.</p>Fórmula:C22H32O4Forma y color:SolidPeso molecular:360.49WAY-605471
CAS:<p>WAY-605471 is a AHR antagonist with IC50 of 0.5 - 1 μM.</p>Fórmula:C14H15NO3S2Pureza:99.62%Forma y color:SolidPeso molecular:309.4MTvkPABC-P5 TFA
<p>MTvkPABC-P5d TFA, a TLR7 agonist, functions as an immune stimulant. It is applicable in the synthesis of immune-stimulating antibody conjugates (ISAC).</p>Forma y color:Odour SolidTopramezone
CAS:<p>Topramezone is a 4-HPPD inhibitor herbicide for post-emergence weed control in corn.</p>Fórmula:C16H17N3O5SForma y color:SolidPeso molecular:363.39PSMA-DA1
CAS:PSMA–DA1 may be a useful PSMA-targeting radiotheranostic agent.Fórmula:C50H76IN9O20Forma y color:SolidPeso molecular:1250.105Bectumomab
CAS:<p>Bectumomab (IMMU-LL2) is a humanized IgG2a mAb targeting CD22, used in imaging and staging non-Hodgkin's lymphoma.</p>Forma y color:Liquid(-)-10,11-Dihydroxyfarnesol
CAS:<p>(-)-10,11-Dihydroxyfarnesol, from Cryptomarasmius aucubae, inhibits NO production.</p>Fórmula:C15H28O3Forma y color:SolidPeso molecular:256.38Chitoheptaose heptahydrochloride
CAS:<p>Chitoheptaose heptahydrochloride, a chitosan derivative, enhances wheat growth and photosynthesis, with health-protective traits.</p>Fórmula:C42H80ClN7O29Forma y color:SolidPeso molecular:1182.573D-Monophosphoryl Lipid (12,16) free acid
CAS:<p>3D-Monophosphoryl Lipid (12,16) (3D-MPL (12,16)) free acid is a TLR agonist that serves as a vaccine adjuvant to boost the immunogenicity of vaccines.</p>Fórmula:C96H181N2O21PForma y color:SolidPeso molecular:1730.44Efmarodocokin alfa
CAS:<p>Efmarodocokin alfa, IL-22/IgG4 fusion protein, activates IL-22 pathways, researched for severe COVID-19 pneumonia.</p>Forma y color:LiquidPorphyra 334
CAS:<p>Porphyra 334 is a mycosporine-like amino acid.</p>Fórmula:C14H22N2O8Forma y color:SolidPeso molecular:346.336Timosaponin E2
CAS:<p>Timosaponin E2 is an anti-inflammatory agent that inhibits active oxygen production [1].</p>Fórmula:C46H78O20Forma y color:SolidPeso molecular:951.1Human Immunoglobulin M
<p>Human Immunoglobulin M (IgM) is an antibody secreted by the adaptive immune system in response to foreign antigens. It is a primary type of immunoglobulin released into circulation during the early stages of the primary antibody response. Human Immunoglobulin M forms a pentamer comprising five IgG equivalents, with 10 Fab fragments, allowing for 10 antigen binding sites. Additionally, Human Immunoglobulin M acts as a complement (complement) activator.</p>Forma y color:Odour SolidMitoquinol
CAS:<p>Mitoquinol is a mitochondria-targeted antioxidant used in the study of cardiovascular disease by modulating the mitochondrial antioxidant defense system.</p>Fórmula:C38H49O7PSPureza:98%Forma y color:SolidPeso molecular:680.83RDR 02308
CAS:<p>RDR 02308 is a TLR4-MyD88 binding inhibitor that inhibits full-length β-lactamase [1] .</p>Fórmula:C19H15N3O3Forma y color:SolidPeso molecular:333.34POT-4 acetate
<p>POT-4 acetate inhibits Complement C3 activation. POT-4 acetate can be used for studies about age-related macular degeneration.</p>Fórmula:C74H106N22O20S2Pureza:98%Forma y color:SolidPeso molecular:1687.9TLR8 agonist 8
CAS:<p>TLR8 agonist8 (Compound II-72) is an agonist of Toll-like receptor 8 (TLR8) with an EC50 of 0.25-1 μM. It demonstrates stability in both human and mouse plasma and induces the secretion of the cytokine TNFα with an EC50 of less than 1 μM. In the MC38-HER2 xenograft mouse model, TLR8 agonist8 exhibits antitumor activity, achieving a tumor growth inhibition (TGI) rate of 89%.</p>Fórmula:C53H63N11O10Forma y color:SolidPeso molecular:1014.14MitoP
CAS:<p>MitoP forms from H2O2 and MitoB, indicating mitochondria's H2O2 levels when measured by LC-MS/MS.</p>Fórmula:C25H22BrOPForma y color:SolidPeso molecular:449.32ADU-S100 disodium salt
CAS:<p>ADU-S100 (MIW815) disodium salt is an activator of stimulator of interferon genes (STING).</p>Fórmula:C20H22N10Na2O10P2S2Pureza:98%Forma y color:SolidPeso molecular:734.51TBK1/IKKε-IN-6
CAS:<p>TBK1/IKKε-IN-6 (example 110) is a potent inhibitor of TBK1 and IKKε, with IC50 values of less than 100 nM for both enzymes.</p>Fórmula:C31H36F2N8O4Forma y color:SolidPeso molecular:622.678Amphimedine
CAS:<p>Amphimedine is a Pyridoacridine Marine Alkaloid.</p>Fórmula:C19H11N3O2Forma y color:SolidPeso molecular:313.3124-Methylenecholesterol
CAS:<p>24-Methylenecholesterol (24 Methylenecholesterol) is a natural marine sterol, which stimulates cholesterol acyl transferase (ACAT) in human macrophages.</p>Fórmula:C28H46OPureza:98%Forma y color:SolidPeso molecular:398.66IFN-α Receptor Recognition Peptide 1
CAS:<p>IFN-α Receptor Recognition Peptide 1, associated with receptor interactions, is a peptide of IFN-α.</p>Fórmula:C35H59N13O12SPureza:98%Forma y color:SolidPeso molecular:885.99Redaporfin
CAS:<p>Redaporfin (F-2BMet, LUZ-11) is a PDT cancer photosensitizer; 83% of mice had tumor regression with 1.5 mg/kg and 74 J/cm² light.</p>Fórmula:C48H38F8N8O8S4Forma y color:SolidPeso molecular:1135.11hSTING activator-1
<p>hSTING activator-1 (Compound 68) is a STING agonist capable of effectively activating various human STING variants (R232, H232, HAQ), with EC50 values of 56 nM, 89 nM, and 51 nM, respectively. This compound activates the type I interferon pathway by directly binding to the STING protein and stabilizing its conformation, which leads to downstream IRF3 phosphorylation and cytokine release. hSTING activator-1 also demonstrates potential in cancer research by inhibiting fibrosarcoma tumor growth.</p>Forma y color:Odour SolidNLRP3-IN-73
<p>NLRP3-IN-73 (W16) is an orally bioavailable inhibitor that disrupts the assembly of the NLRP3 inflammasome, exhibiting an IC50 value of 0.18 μM for the NLRP3/IL-1β pathway.</p>Forma y color:Odour SolidBiotin-labeled ODN TTAGGG sodium
<p>Biotin-labeled ODN TTAGGG (sodium) is an inhibitory oligonucleotide (ODN) that functions as an antagonist to TLR9, AIM2, and cGAS.</p>Forma y color:Odour SolidNLRP3-IN-50
<p>NLRP3-IN-50 (compound SN3-1) is a potential inhibitor of NLRP3, offering therapeutic promise for inflammatory diseases.</p>Fórmula:C23H22Cl2N2O4S2Forma y color:SolidPeso molecular:525.47GHN105
<p>GHN105 is an orally active STING inhibitor that suppresses STING-dependent IFN-β secretion in THP-1 human monocytes with an IC50 of 4.4 μM. In mice, GHN105 reduces serum levels of IFN-β, IL-6, and CXCL10, and alleviates colitis in a DSS-induced acute colitis mouse model. Additionally, GHN105 demonstrates favorable pharmacokinetic properties in mice, with an oral bioavailability of 43% and a half-life of 1.1 hours.</p>Fórmula:C41H56N2O14Forma y color:SolidPeso molecular:800.89Inflexuside A
CAS:<p>Inflexuside A, an abietane diterpenoid from Isodon inflexus, and Inflexuside B inhibit NO in LPS-stimulated RAW264.7 cells.</p>Fórmula:C26H42O9Forma y color:SolidPeso molecular:498.61Prifelone
CAS:<p>Prifelone (R 830) is a non-steroidal anti-inflammatory compound with antioxidant activity.</p>Fórmula:C19H24O2SPureza:99.8%Forma y color:SolidPeso molecular:316.46Dibenzothiophene
CAS:<p>Dibenzothiophene, a sulfur PAH in petroleum, has 3 rings and keratolytic properties.</p>Fórmula:C12H8SPureza:99.82%Forma y color:Yellow To Green SolidPeso molecular:184.26RH-EDA
<p>RH-EDA, a rhodamine-based turn-on fluorescent probe, detects hydroxyl radicals ([OH]) in living systems.</p>Fórmula:C28H25N3O4Forma y color:SolidPeso molecular:467.52MC4762
<p>MC4762 is an inhibitor of NOX2 and MAOB, with IC50 values of 0.155 μM and 0.182 μM, respectively. It exhibits anti-inflammatory properties by suppressing the production of ROS and downregulating the expression of pro-inflammatory cytokines such as iNOS, IL-1β, and IL-6.</p>Forma y color:Odour SolidSuc-Tyr-Val-Ala-Asp-pNA
CAS:<p>Suc-YVAD-pNA, a chromogenic caspase-1 substrate.</p>Fórmula:C31H38N6O12Forma y color:SolidPeso molecular:686.675Perfluorohexane
CAS:<p>Perfluorohexane (AF-0150) is a perfluorocarbon (PFC)-based microbubble formulation for ultrasound contrast and is developmentally toxic.</p>Fórmula:C6F14Pureza:98%Forma y color:Colourless LiquidPeso molecular:338.04NOD2 agonist 2
<p>NOD2 agonist 2 (compound 23) enhances antigen presentation in murine bone marrow-derived dendritic cells (BMDCs), highlighting its potential as a vaccine adjuvant.</p>Fórmula:C46H65N3O10Forma y color:SolidPeso molecular:820.02Mifamurtide TFA
<p>Mifamurtide TFA: muramyl dipeptide analog, boosts immunity, activates macrophages/monocytes, potential osteosarcoma research.</p>Fórmula:C61H110F3N6O21PForma y color:SolidPeso molecular:1351.52TSR-033
CAS:<p>TSR-033 is a human IgG4 antibody with high affinity for LAG-3 (lymphocyte activation gene-3), a co-receptor linked to diminished T cell activity, frequently co-</p>Forma y color:LiquidFlunixin
CAS:<p>Flunixin is a nonsteroidal anti-inflammatory drug (NSAID), antipyretic, and analgesic used in pigs, horses, and cattle.</p>Fórmula:C14H11F3N2O2Forma y color:SolidPeso molecular:296.24Antifungal agent 123
<p>Antifungalagent 123 (Compound 4b) demonstrates strong affinity for the oxidoreductase of Staphylococcus aureus or membrane proteins of Candida albicans, exhibiting both antibacterial and antifungal properties. Additionally, it is capable of scavenging free radicals, showcasing antioxidant effects. Antifungalagent 123 also inhibits the TLR signaling pathway and possesses anti-inflammatory activity.</p>Fórmula:C21H20N4O3Forma y color:SolidPeso molecular:376.409Vemircopan
CAS:<p>Vemircopan is a complement factor D inhibitor.</p>Fórmula:C29H28BrN7O3Forma y color:SolidPeso molecular:602.493Inflexuside B
CAS:<p>Inflexuside B, an abietane diterpenoid derived from the aerial parts of Isodon inflexus, effectively inhibits lipopolysaccharide (LPS)-activated NO Synthase in</p>Fórmula:C35H48O11Forma y color:SolidPeso molecular:644.75Guaiacol-d3
CAS:<p>Guaiacol-d3 is a deuterated form of Guaiacol, which is a phenolic compound known for its ability to inhibit COX-2 expression and NF-κB activation in response to LPS stimulation, exhibiting anti-inflammatory properties.</p>Fórmula:C7H8O2Forma y color:SolidPeso molecular:127.16PSMA-ALB-56
CAS:<p>PSMA-ALB-56: radioactive, PSMA-targeted ligand, antitumor, combines glutamic urea, DOTA, albumin, with iodophenyl or tolyl fragments.</p>Fórmula:C66H95N11O18Forma y color:SolidPeso molecular:1330.52RS 09 TFA
<p>RS 09 TFA is a TLR4 agonist and LPS peptide analogue, promotes NF-κB nuclear translocation, induces inflammatory cytokine secretion in RAW264.7 macrophages.</p>Fórmula:C33H50F3N9O11Pureza:99.78%Forma y color:SolidPeso molecular:805.8CD19 CAR mRNA
<p>CD19 CAR mRNA expresses a protein for use in CAR-CD19 T cell therapy, targeting B cell antigen for cancer treatment.</p>Forma y color:Solid4-hydroperoxy 2-Nonenal
CAS:<p>4-HNE, a marker of oxidative stress, arises from oxidized ω-6 fats like linoleic acid and shows cytotoxic and genotoxic effects.</p>Fórmula:C9H16O3Forma y color:SolidPeso molecular:172.224BMS-986148
<p>BMS-986148 is a CHO-expressed humanized antibody-drug coupling targeting mesothelin-expressing cells for cytotoxic load delivery.</p>Pureza:98.1% (SDS-PAGE); 99% (SEC-HPLC) - 98.1% (SDS-PAGE); 99% (SEC-HPLC)Forma y color:Odour LiquidBermoprofen
CAS:<p>Bermoprofen (AD-1590) is an anti-inflammatory compound with anti-inflammatory and analgesic activity used in the study of gastric ulcers.</p>Fórmula:C18H16O4Pureza:98.72% - 99.28%Forma y color:SolidPeso molecular:296.32IL-6-IN-1
<p>IL-6-IN-1 (Compound 22) inhibits the release of IL-6 with an IC50 of 1.065 μM and demonstrates anti-inflammatory activity in LPS-induced acute lung injury in mice.</p>Fórmula:C16H12N2OSForma y color:SolidPeso molecular:280.34PSMA-D5
CAS:<p>PSMA-D5 exhibits a binding affinity for PSMA with a Ki of 0.21 nM and becomes useful for PSMA tracing following radiolabeling. When marked with [68Ga], PSMA-D5 contains a DOTA chelator, facilitating the convenient labeling with therapeutic radionuclides such as 177Lu and 225Ac. Additionally, [68Ga]-labeled PSMA-D5 demonstrates exceptional pharmacokinetic properties and significant tumor uptake in 22Rv1 tumors. This compound can be employed in the synthesis and research of radiolabeled conjugates (RDC).</p>Fórmula:C57H80N12O24Forma y color:SolidPeso molecular:1317.312'2'-cGAMP (sodium salt)
CAS:<p>2'2'-cGAMP, a synthetic CDN, binds STING in the immune response, inducing IFN-β; binds weaker than 2'3'-cGAMP but stronger than other CDNs.</p>Fórmula:C20H24N10O13P2Forma y color:SolidPeso molecular:674.417Dazostinag
CAS:<p>Dazostinag (TAK-676) is a STING agonist with anti-cancer properties, used in making ADCs.</p>Fórmula:C21H22F2N8O10P2S2Forma y color:SolidPeso molecular:710.524-Methylamino antipyrine hydrochloride
CAS:<p>4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole.</p>Fórmula:C12H16ClN3OPureza:98%Forma y color:SolidPeso molecular:253.73JPE-1375
CAS:<p>JPE-1375: a C5aR1 antagonist, blocks leukocyte mobilization (EC50=6.9 µM), lowers TNF in mice (EC50=4.5 µM), useful for autoimmune/inflammation research.</p>Fórmula:C49H63FN10O9Forma y color:SolidPeso molecular:955.08HS-243
CAS:<p>HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.</p>Fórmula:C17H16N4O3Pureza:98.62%Forma y color:SolidPeso molecular:324.33Axinelline A
CAS:<p>Axinelline A: COX inhibitor, IC50 of 2.22 μM (COX-2) & 8.89 μM (COX-1), anti-inflammatory.</p>Fórmula:C12H15NO6Forma y color:SolidPeso molecular:269.25NG-Hydroxy-L-arginine acetate
CAS:<p>NG-Hydroxy-L-arginine acetate (NOHA acetate) acts as a crucial physiological inhibitor of arginase, playing a vital role in the conversion of arginine to nitric oxide and citrulline via nitric oxide synthase.</p>Fórmula:C6H14N4O3xC2H4O2Forma y color:SolidPeso molecular:190.20（free base）STING-IN-13
<p>STING-IN-13 is a selective STING inhibitor that effectively suppresses downstream signaling of the STING pathway and STING-mediated inflammation. It exhibits low toxicity and is suitable for research related to STING-associated inflammatory and autoimmune diseases.</p>Forma y color:Odour SolidBiotin-labeled Agatolimod sodium
<p>Biotin-labeled Agatolimod (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of cellular uptake and localization of</p>Forma y color:Odour SolidBiotin-labeled ODN 2216 sodium
<p>Biotin-labeled ODN 2216 (sodium) serves as a specific agonist for human TLR9 (toll-like receptor 9), facilitating the assessment of CpG ODN cellular uptake and</p>Forma y color:Odour SolidAntitumor agent-188
<p>Antitumor agent-188 (compound C6) exhibits α-glucosidase inhibitory activity and anticancer properties. It induces excessive ROS production, thereby triggering oxidative stress.</p>Fórmula:C25H44FN3O7Forma y color:SolidPeso molecular:517.63CU-115
CAS:<p>CU-115 is a selective and potent TLR8 antagonist with IC50 of 1.04 µM and =>50 µM for TLR8 and TLR7, respectively.</p>Fórmula:C21H11F7INO2Pureza:99.96%Forma y color:SolidPeso molecular:569.21diABZI STING agonist-1 trihydrochloride
CAS:<p>diABZI STING agonist-1 (trihydrochloride) is stimulator of interferon genes (STING) receptor agonist.</p>Fórmula:C42H54Cl3N13O7Pureza:95.33% - 99.55%Forma y color:SolidPeso molecular:959.32Multinoside A
CAS:<p>Multinoside A is a useful organic compound for research related to life sciences. The catalog number is T124593 and the CAS number is 59262-54-3.</p>Fórmula:C27H30O16Forma y color:SolidPeso molecular:610.521(Rac)-γ-Tocopherol
CAS:<p>(Rac)-γ-Tocopherol (DMPBQ) is an isoform of Vitamin E that undergoes conversion to γ-Tocopherol through the action of tocopherol cyclase.</p>Fórmula:C28H48O2Forma y color:SolidPeso molecular:416.68Carboxy-PTIO
CAS:<p>Carboxy-PTIO rapidly scavenges NO, forming NO2, key in preventing hypotension and shock in rats.</p>Fórmula:C14H17N2O4Forma y color:SolidPeso molecular:277.3STING agonist-25
CAS:<p>STING agonist-25 is a non-nucleotide that activates STING, enhances immune response, and is active against SARS-CoV strains.</p>Fórmula:C36H41N13O6Forma y color:SolidPeso molecular:751.79NLRP3-IN-15
CAS:<p>NLRP3-IN-15: potent, selective NLRP3 inflammasome inhibitor; IC50 0.114 μM for IL-1β; for inflammation research.</p>Fórmula:C22H19NO4Forma y color:SolidPeso molecular:361.39QKY-613
CAS:<p>QKY-613 is a prodrug designed to enhance immune surveillance by targeting nucleic acid modification pathways. It selectively facilitates the incorporation of 6mdA (N6-methyl-deoxyadenosine) into viral DNA, boosting the DNA's phase separation potential and subsequently increasing cGAS activation levels to strengthen host immune surveillance. In mouse models of viral infection, QKY-613 significantly reduced mortality in aged mice. This compound holds promise for studying immune surveillance mechanisms based on nucleic acid modifications.</p>Fórmula:C27H31N6O7PForma y color:SolidPeso molecular:582.55Decylubiquinone
CAS:<p>Decylubiquinone (DUb) is a coenzyme Q10 analog with anticancer activity, inhibiting the growth and metastasis of breast cancer.</p>Fórmula:C19H30O4Pureza:99.32% - 99.92%Forma y color:SolidPeso molecular:322.44Anti-inflammatory agent 93
<p>Compound 2g (Anti-inflammatory agent 93) is an active compound that exhibits analgesic activity.</p>Fórmula:C27H17Cl2N3O2Forma y color:SolidPeso molecular:486.35CRX-526
CAS:<p>CRX-526, a TLR4 antagonist, protects against advanced diabetic nephropathy.</p>Fórmula:C69H127N2O19PPureza:98%Forma y color:SolidPeso molecular:1319.72IMGN-779
<p>IMGN-779 (Anti-CD33 Antibody) is a humanized antibody targeting CD33 with antileukemic activity, which can be used to study leukemia.</p>Pureza:>95%Forma y color:Odour Liquid2-Iminobiotin
CAS:<p>2-Iminobiotin inhibits iNOS/nNOS; Ki: 21.8 μM (mouse iNOS), 37.5 μM (rat nNOS).</p>Fórmula:C10H17N3O2SPureza:98%Forma y color:SolidPeso molecular:243.33Anti-Human MSLN Antibody (Clone HN1)
<p>Anti-Human MSLN Antibody (Clone HN1) is a humanised monoclonal antibody targeting MSLN (Mesothelin), , blocks the interaction between MSLN and CA125, cancer .</p>Pureza:95%Forma y color:Odour LiquidCbl-b-IN-28
<p>Cbl-b-IN-28 (Compound B2) is an orally active Cbl-b inhibitor. It enhances the function of immune cells by promoting the secretion of cytokines like IL-2 and modulating the phosphorylation levels of key proteins in the T cell receptor signaling pathway. Cbl-b-IN-28 is applicable in cancer immunology research.</p>Forma y color:Odour SolidLY-402913
CAS:<p>LY-402913 is a selective multidrug resistance protein (MRP1) inhibitor.</p>Fórmula:C28H24ClN3O6Pureza:99.73%Forma y color:SolidPeso molecular:533.96PSB-12379 ditriethylamine salt
<p>PSB-12379 ditriethylamine salt, a nucleotide analogue, is a potent Ecto-5'-Nucleotidase (CD73) inhibitor with Kis of 9.03 nM (rat) and 2.21 nM (human).</p>Fórmula:C30H53N7O9P2Pureza:98.26% - 99.44%Forma y color:SolidPeso molecular:717.73iNOs-IN-6
<p>iNOs-IN-6 is an anti-inflammatory agent known for inhibiting the expression of NF-κB, iNOS, and MAPK with an IC50 ranging from 0.2 to 0.62 μM. Additionally, it decreases the levels of pro-inflammatory mediators, such as IL-6, TNF-α, and IL-1β, with an IC50 ranging from 0.4 to 0.69 μM.</p>Forma y color:Odour SolidDithianon
CAS:<p>Dithianon: broad-spectrum anthraquinone fungicide; sticks to leaves/fruits; controls various fungi in some produce.</p>Fórmula:C14H4N2O2S2Pureza:98%Forma y color:SolidPeso molecular:296.32Vadastuximab
<p>Vadastuximab (Anti-Human CD33 Recombinant Antibody) is a humanized anti-CD33 monoclonal antibody for the study of acute myeloid leukemia (AML).</p>Pureza:98.5% (SDS-PAGE); 97.3% (SEC-HPLC) - 98.5% (SDS-PAGE); 97.3% (SEC-HPLC)Forma y color:LiquidPeso molecular:145.5 kDaCRX 527
CAS:<p>CRX 527 is a TLR4 ligand and serves as an adjuvant for peptide cancer vaccines, enhancing anti-tumor immune responses. CRX 527 also induces hematopoietic stem cell (HSC) differentiation, increasing the proportion and number of LSK cells, and promotes their differentiation into macrophages. This activation bolsters immune defense and protects intestinal epithelium from radiation damage.</p>Fórmula:C81H151N2O19PForma y color:SolidPeso molecular:1488.04Siegesbeckialide I
<p>Siegesbeckialide I effectively suppresses LPS-induced NO production in RAW264.7 murine macrophages by directly interacting with IKKα/β.</p>Fórmula:C20H28O6Forma y color:SolidPeso molecular:364.43SN50
CAS:<p>SN50 is a cell-permeable inhibitor of NF-κB nuclear translocation that protects against ventilator-induced acute lung injury in rats.</p>Fórmula:C129H230N36O29SPureza:99.91%Forma y color:SolidPeso molecular:2781.5Damnacanthol
<p>Damnacanthol is a useful organic compound for research related to life sciences and the catalog number is T131609.</p>Fórmula:C16H12O5Forma y color:SolidPeso molecular:284.267Prezalumab
CAS:<p>Prezalumab (AMG 557) is a human IgG2 monoclonal antibody against ICOSL and BAFF.</p>Pureza:> 95%Forma y color:LiquidPeso molecular:145.42 kDaPSMα3
CAS:<p>PSMα3 is a peptide compound that can be utilized to induce tolerance in dendritic cells (DCs) for DC vaccination strategies.</p>Fórmula:C128H192N28O30SForma y color:SolidPeso molecular:2635.174'-hydroxy Flurbiprofen
CAS:<p>4'-hydroxy Flurbiprofen can be used in related research in the field of life sciences. Its product number is T35722 and CAS number is 52807-12-2.</p>Fórmula:C15H13FO3Forma y color:SolidPeso molecular:260.264TPNA10168
CAS:<p>Compound Fr13590, with CAS No. 957942-34-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr13590 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C9H9ClO2S2Forma y color:SolidPeso molecular:248.75SN50 TFA
<p>SN50 TFA is an inhibitor of NF-κB and attenuates alveolar hypercoagulation and fibrinolysis inhibition. SN50 TFA can be used in studies about ARDS.</p>Fórmula:C129H230N36O29S·XCF3COOHForma y color:SolidPeso molecular:2781.5 (free base)Somantadine
CAS:<p>Somantadine has antiviral activities and can be used for research on preventing and treating coronavirus-related diseases.</p>Fórmula:C14H25NPureza:99.9%Forma y color:SolidPeso molecular:207.35β-Interleukin II (44-56)
<p>β-Interleukin II is a peptide with the sequence NH2-ILE-LEU-ASN-GLY-ILE-ASN-ASN-TYR-LYS-ASN-PRO-LYS-LEU-COOH.</p>Fórmula:C68H113N19O19Pureza:98%Forma y color:SolidPeso molecular:1500.74QX-005N
QX 005N is a humanized monoclonal anti-CD124/IL4R/IL-4Rα antibody. It is applicable in research related to asthma.Forma y color:Odour LiquidAntiviral agent 61
<p>Antiviralagent 61 (compound Z40) serves as an effective antiviral agent with activity against Tomato Spotted Wilt Virus (TSWV), exhibiting an EC50 value of 252 µg/mL. It increases the RNA expression of Ndufb9, COX6B, 7.1.2.2, E, COX5B, Ndufs4, and SDHB, while reducing the expression of Ndufb7, Ndufa5, and G.</p>Fórmula:C22H23N5O4SForma y color:SolidPeso molecular:453.51Pepinh-MYD
CAS:<p>Pepinh-MYD, a MyD88 inhibitor, incorporates both a domain sequence from MyD88 TIR and a protein transduction sequence to facilitate cell membrane penetration. This compound disrupts MyD88-mediated TLR signaling pathways, effectively inhibiting associated immune responses. Its design is particularly useful for investigating MyD88's function in viral infections.</p>Fórmula:C151H248N50O35S2Forma y color:SolidPeso molecular:3388.03Pelgifatamab
CAS:<p>Pelgifatamab (BAY-2315497) is a prostate-specific membrane antigen (PSMA) antibody with potential anticancer activity that can be used to study prostate cancer.</p>Pureza:97.9% (SDS-PAGE); 95.1% (SEC-HPLC) - 97.9% (SDS-PAGE); 95.1% (SEC-HPLC)Forma y color:LiquidEnglumafusp alfa
<p>Englumafusp alfa (CD19-4-1BBL; RO7227166) is a fusion protein combining a CD19-specific antibody domain with trimerized extracellular domains of human 4-1BBL,</p>Forma y color:Odour LiquidMS7829
<p>MS7829 is a first-class DUBTAC targeting cGAS, a critical component in the cGAS-STING pathway.</p>Forma y color:Odour SolidABX-IL8
<p>ABX-IL8 is a humanized antibody targeting IL-8, capable of interfering with tube formation in human umbilical vein endothelial cells.</p>Pureza:>95%Forma y color:LiquidPeso molecular:145.5 kDaTD139
CAS:<p>TD139 is an inhaled small molecule inhibitor of galectin-3 (Gal-3) with potential anti-fibrotic activity. Cost-effective and quality-assured.</p>Fórmula:C28H30F2N6O8SPureza:97.82% - 99.66%Forma y color:SolidPeso molecular:648.64AHR antagonist 5 free base
CAS:<p>AHR antagonist 5 free base is an orally active AHR antagonist and exhibits anticancer activity.Cost-effective and quality-assured.</p>Fórmula:C25H24FN7Pureza:99.88%Forma y color:SolidPeso molecular:441.5FITC-labeled ODN 2395 sodium
<p>FITC-labeled ODN 2395 (sodium), a class C oligodeoxynucleotide and TLR9 agonist, facilitates the assessment of CpG ODN cellular uptake and localization through</p>Forma y color:Odour SolidIACS-8803 diammonium
<p>IACS-8803 diammonium, a potent cyclic dinucleotide STING agonist, demonstrates robust systemic antitumor efficacy [1].</p>Fórmula:C20H29FN12O9P2S2Forma y color:SolidPeso molecular:726.6CIB-1476
<p>CIB-1476, a caspase-1 inhibitor, effectively reduces joint swelling in mouse models of arthritis and demonstrates lasting anti-inflammatory effects. This compound achieves its benefits by blocking IL-1β production, NF-κB activation, and GSDMD-mediated pyroptosis, all of which are triggered by the NLRP3 inflammasome.</p>Fórmula:C28H28N2O6SForma y color:SolidPeso molecular:520.6Septeremophilane E
<p>Septeremophilane E, from Septoria rudbeckiae fungus, inhibits NO production.</p>Fórmula:C21H26O5Forma y color:SolidPeso molecular:358.43OVA Peptide(257-264)
CAS:<p>OVA Peptide(257-264) is an ovalbumin octamer Peptide expressed by class I MHC molecule h-2kb.</p>Fórmula:C45H74N10O13Pureza:99.53%Forma y color:SolidPeso molecular:963.13Pirenoxine
CAS:<p>Pirenoxine is an agent with anti-cataractogenesis activity by interacting with calcium ions or selenite which could lead to the formation of lens cataract.</p>Fórmula:C16H8N2O5Forma y color:SolidPeso molecular:308.25Dovanvetmab
CAS:<p>Dovanvetmab (ZTS-00521505) is an IgG1-κ monoclonal antibody that targets feline interleukin 31 (Felcat IL31), primarily produced in Chinese Hamster Ovary (CHO)</p>Forma y color:LiquidDecamethylene glycol
CAS:<p>Decamethylene glycol, a reagent for studying modified oligonucleotides with anticancer effects, is also researched in myrrh and frankincense oil composition.</p>Fórmula:C10H22O2Pureza:98%Forma y color:White Crystals Or PowderPeso molecular:174.28R-HP210
<p>R-HP210 blocks LPS-triggered IL-1β, IL-6, COX-2 gene transcription and has a 3.80 μM IC50 for NF-κB inhibition without activating GCs.</p>Fórmula:C22H19N3O2S2Forma y color:SolidPeso molecular:421.54diABZI-V/C-DBCO
<p>Compound 3 (diABZI-V/C-DBCO) functions as an efficient STING agonist. This compound acts by releasing diABZI-amine under the action of cathepsin B to activate STING, thereby inducing the production of interferon and other immune-activating molecules, which enhances the immune system's response to tumors. In THP1-Dual cells, the EC50 values for STING activation by diABZI-V/C-DBCO and diABZI-amine are 1.47 nM and 0.144 nM, respectively, and in primary mouse splenic cells, the EC50 values are 7.7 µM and 0.17 µM, respectively. diABZI-V/C-DBCO is useful for research in the field of cancer immunotherapy.</p>Fórmula:C78H89N19O13Forma y color:SolidPeso molecular:1500.66Tri(TLR4-IN-C34-PEG2-amide-PEG1)-amide-C3-COOH
<p>Tri(TLR4-IN-C34-PEG2/PEG1)-amide-C3-COOH is a TLR4 inhibiting linker, reducing inflammation in endotoxemia and enterocolitis mouse models.</p>Fórmula:C78H125N7O42Forma y color:SolidPeso molecular:1832.85Paneolilludinic acid
CAS:<p>Paneolilludinic acid from Cryptomarasmius aucubae fungus inhibits NO production.</p>Fórmula:C15H22O3Forma y color:SolidPeso molecular:250.33M-5011
CAS:<p>M-5011: NSAID and immunomodulator for pain and inflammation; ED50 0.63mg/kg; reduces bone loss in arthritis; low ulcer risk.</p>Fórmula:C14H14O2SPureza:98%Forma y color:SolidPeso molecular:246.32Pegaldesleukin
CAS:<p>Pegaldesleukin, a PEG-IL2 conjugate, exhibits antiviral properties, potentially slowing HIV progression, preserving immune function.</p>Forma y color:LiquidAra-F-NAD+ sodium
<p>Ara-F-NAD+ sodium, an arabino analogue of NAD+, serves as a potent, reversible, and slow-binding inhibitor of the CD38 NADase [1] [2].</p>Fórmula:C21H25FN7NaO13P2Forma y color:SolidPeso molecular:687.4NLRP3-IN-45
<p>NLRP3-IN-45 (D6) serves as an inhibitor specifically targeting the NLRP3 inflammasome, demonstrated through its ability to curb the activity of IL-1β (IC 50 = 41.79 nM). It effectively prevents the activation of the NLRP3 inflammasome while sparing the initial stages of its activation process. Furthermore, NLRP3-IN-45 has been shown to selectively inhibit NLRP3 inflammasome activation in the LPS-induced acute lung injury (ALI) mouse model.</p>Fórmula:C27H30FNO6Forma y color:SolidPeso molecular:483.53Eramkafusp Alfa
<p>Eramkafusp alfa is a human IgG1 antibody that targets the murine B lymphocyte antigen CD20, also known as MS4A1 [1].</p>Forma y color:Odour LiquidAβ-IN-6
<p>Aβ-IN-6 is an orally active compound exhibiting anti-inflammatory, antioxidant, and anti-oligomeric activities, with significant implications for Alzheimer's</p>Fórmula:C28H31N3O4Forma y color:SolidPeso molecular:473.56CHBO4
CAS:<p>CHBO4 is an hMAO-B inhibitor that is potent, reversible, competitive and selective.The IC50 value of CHBO4 against hMAO-B in the CHBO assay was 0.031 μM, and</p>Fórmula:C15H10BrFOPureza:98.14%Forma y color:SolidPeso molecular:305.14HNGF6A
CAS:<p>increases glucose stimulated insulin secretion and glucose metabolism</p>Fórmula:C112H198N34O31S2Pureza:98%Forma y color:SolidPeso molecular:2581.11Withangulatin A
CAS:<p>Withangulatin A, a COX-2 inhibitor from Physalis angulata, has anti-tumor and anti-inflammatory effects.</p>Fórmula:C30H38O8Forma y color:SolidPeso molecular:526.62Mesalamine impurity P
CAS:<p>Mesalamine impurity P, a 5-Aminosalicylic acid derivative, is a PPARγ agonist, inhibiting PAK1 and NF-κB.</p>Fórmula:C13H11NO6SForma y color:SolidPeso molecular:309.30Siplizumab
CAS:<p>Siplizumab (MEDI-507), an IgG1 antibody targeting CD2, depletes T cells, may treat psoriasis.</p>Pureza:100% (SEC-HPLC) - > 95%Forma y color:LiquidPeso molecular:147.24 kDaNrf2 activator 18
<p>Nrf2 activator 18 (Compound 11a) is an orally active activator of the Keap1/Nrf2/HO-1 signaling pathway, promoting Nrf2 nuclear translocation and enhancing antioxidant effects. It inhibits IL-6 release with an IC50 of 4.816 μM. In a mouse model of PM2.5-induced lung injury, Nrf2 activator 18 demonstrates anti-inflammatory activity.</p>Fórmula:C23H24FN3OForma y color:SolidPeso molecular:377.45
