Inmunología e inflamación
Los inhibidores de inmunología e inflamación son compuestos que modulan la respuesta inmunitaria y los procesos inflamatorios. Estos inhibidores son cruciales para estudiar los mecanismos de regulación inmunitaria, la autoinmunidad y la inflamación crónica, así como para desarrollar tratamientos para enfermedades inflamatorias, alergias y trastornos relacionados con el sistema inmunológico. Al dirigirse a vías clave en el sistema inmunológico, estos inhibidores pueden ayudar a reducir las respuestas inmunitarias excesivas o inadecuadas. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad para apoyar su investigación en inmunología, inflamación y desarrollo terapéutico.
Subcategorías de "Inmunología e inflamación"
- CCR(136 productos)
- CXCR(149 productos)
- Pared celular(5 productos)
- Receptor de IL(112 productos)
- IκB / IKK(59 productos)
- LTR(3 productos)
- MALT(23 productos)
- MRP(6 productos)
- NADPH-oxidasa(1 productos)
- NF-κB(443 productos)
- NOD(18 productos)
- NOS(63 productos)
- Nrf2(78 productos)
- PGE sintasa(31 productos)
- ROS(69 productos)
- TGF-beta / Smad(58 productos)
- TLR(66 productos)
- Tiorredoxina(12 productos)
- gp120 / CD4(4 productos)
Mostrar 11 subcategorías más
Se han encontrado 3054 productos de "Inmunología e inflamación"
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RS 09 TFA
<p>RS 09 TFA is a TLR4 agonist and LPS peptide analogue, promotes NF-κB nuclear translocation, induces inflammatory cytokine secretion in RAW264.7 macrophages.</p>Fórmula:C33H50F3N9O11Pureza:99.78%Forma y color:SolidPeso molecular:805.8PSB-12379 disodium
<p>PSB-12379 disodium is a nucleotide analogue acting as a potent inhibitor of Ecto-5'-Nucleotidase (CD73), demonstrating inhibitory constants (Ki) of 9.03 nM in</p>Fórmula:C18H21N5Na2O9P2Forma y color:SolidPeso molecular:559.31CNTO4088
CNTO4088 is a monoclonal antibody inhibitor that targets interleukin-23 (IL-23). It holds potential for research in autoimmune diseases such as psoriasis and rheumatoid arthritis.Forma y color:Odour Liquid(R)-(-)-Ibuprofen
CAS:<p>(R)-(-)-Ibuprofen ((R)-Ibuprofen) is the R enantiomer of Ibuprofen and inhibits NF-κB activation.</p>Fórmula:C13H18O2Pureza:99.86%Forma y color:SolidPeso molecular:206.28NLRP3 agonist 2
<p>NLRP3 agonist 2 (compound 22) is an orally active agent that activates Caspase-1 in THP1 cells [1].</p>Pureza:98%Forma y color:Odour SolidTLR8 agonist 2
CAS:<p>TLR8 agonist 2 activates human TLR8 (EC50=3nM), less effective on TLR7 (EC50=33.33μM).</p>Fórmula:C16H22N8Forma y color:SolidPeso molecular:326.408KD014
<p>KD014 (DX-2400) is a human monoclonal antibody (mAb) that targets MMP14, with a Ki of 0.9 nM. It inhibits TGFβ and SMAD2/3 signaling, increases macrophage count and iNOS expression, and shifts macrophage phenotype towards an antitumor M1-like type. KD014 exhibits antitumor activity in three tumor models (MDA-MB-231, MDA-MB-435, and PC3) and is applicable in breast cancer research.</p>Forma y color:Odour Liquid3-Hydroxykynurenamine
CAS:<p>3-Hydroxykynurenamine (3-HKA) is a tryptophan metabolite with anti-inflammatory effects, reducing cytokines and aiding in models of psoriasis and nephritis.</p>Fórmula:C9H12N2O2Forma y color:SolidPeso molecular:180.2Keap1-Nrf2-IN-27
<p>Keap1-Nrf2-IN-27 is an inhibitor of the Keap1-Nrf2 protein-protein interaction (PPI) with a KD2 value of 0.119 μM. It suppresses the expression of pro-inflammatory cytokines TNF-α and IL-6 in an LPS-induced RAW264.7 cell model.</p>Forma y color:Odour SolidTaplitumomab paptox
CAS:<p>Taplitumomab paptox is an anti-CD19 monoclonal antibody utilized in cancer research.</p>Forma y color:LiquidTorudokimab
<p>Torudokimab (ZB-880) is a monoclonal antibody that neutralizes interleukin 33 and can be used to study immune system diseases.</p>Pureza:95.8% (SDS-PAGE); 96.2% (SEC-HPLC) - 95.8% (SDS-PAGE); 96.2% (SEC-HPLC)Forma y color:Odour LiquidLobuprofen
CAS:<p>Lobuprofen is a small molecule COX inhibitor that is used to treat neurological disorders.</p>Fórmula:C25H33ClN2O2Pureza:99.18%Forma y color:SolidPeso molecular:428.99BAY-069
CAS:<p>BAY-069 blocks BCAT1 (IC50:31 nM) & BCAT2 (IC50:153 nM), useful for cancer research.</p>Fórmula:C22H14ClF3N2O3Pureza:99.58%Forma y color:SoildPeso molecular:446.81Keap1-IN-1
<p>Keap1-IN-1 (Compound 27) is an inhibitor of Keap1, functioning by covalently modifying the Cys151 residue on the BTB domain of KEAP1, thereby disrupting the interaction between Keap and Nrf. It enhances the mRNA expression of the antioxidant response element (ARE) dependent gene NQO1, with an EC50 of 160 nM, and exhibits cytotoxicity in U2OS cells, with an EC50 of 527 nM.</p>Fórmula:C17H21Cl2N2O5PS3Forma y color:SolidPeso molecular:531.434XJB-5-131
CAS:<p>XJB-5-131: synthetic, bi-functional antioxidant; targets mitochondria, scavenges ROS/electrons, protects CB MNCs from irradiation.</p>Fórmula:C53H80N7O9Forma y color:SolidPeso molecular:959.2634-ACETAMIDOANTIPYRINE
CAS:<p>4-ACETAMIDOANTIPYRINE, with CAS No. 83-15-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-ACETAMIDOANTIPYRINE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C13H15N3O2Forma y color:SolidPeso molecular:245.28Mepolizumab
CAS:<p>Mepolizumab (SB 240563) is a humanized monoclonal antibody neutralizing IL-5.</p>Pureza:98% - 98%Forma y color:LiquidPU23
CAS:<p>PU 23 is an inhibitor of multidrug-resistant protein 4 (MRP4).</p>Fórmula:C21H19N3O3S2Pureza:99.52%Forma y color:SolidPeso molecular:425.52S7
CAS:<p>S7, an IL-6 receptor antagonist, prevents the interaction between IL-6 and IL-6R, thereby inhibiting angiogenesis and tumor growth [1].</p>Fórmula:C37H70N10O10Forma y color:SolidPeso molecular:815.01Avatrombopag hydrochloride
CAS:<p>Avatrombopag (AKR-501) - oral, nonpeptide TPO receptor agonist, EC50 3.3 nM, boosts platelet production, CYP2C9 and CYP3A substrate.</p>Forma y color:SolidGB2095
<p>GB2095 is an orally effective and selective inhibitor of galectin-3, exhibiting binding affinities (Kd) of 36 nM for human galectin-3 and 0.35 μM for mouse galectin-3. In mouse models, GB2095 demonstrates antitumor activity.</p>Fórmula:C20H17BrClF2N3O4SForma y color:SolidPeso molecular:548.7853D-Monophosphoryl Lipid (12,16) free acid
CAS:3D-Monophosphoryl Lipid (12,16) (3D-MPL (12,16)) free acid is a TLR agonist that serves as a vaccine adjuvant to boost the immunogenicity of vaccines.Fórmula:C96H181N2O21PForma y color:SolidPeso molecular:1730.44C5a Receptor agonist, mouse, human
CAS:<p>C5a Receptor Agonist (mouse, human) is a bioactive peptide derived from the C-terminus of the complement fragment 5 anaphylatoxin (C5a), functioning as an</p>Fórmula:C44H72N10O7Pureza:98%Forma y color:SolidPeso molecular:853.11Schiarisanrin A
CAS:<p>Schiarisanrin A (Kadsulignan J), a lignan, exhibits inhibitory activity on nitric oxide (NO) production, demonstrating an IC50 of 9.6 μM in BV-2 cells [1].</p>Fórmula:C27H32O8Pureza:98%Forma y color:SolidPeso molecular:484.54RIPK2/3-IN-1
<p>RIPK2/3-IN-1 is a potent inhibitor of both RIPK2 and RIPK3 kinases, exhibiting IC50 values of 3 nM for RIPK2 and 117 nM for RIPK3.</p>Fórmula:C24H16N4O2S2Pureza:98%Forma y color:SolidPeso molecular:456.54Siegesbeckialide I
<p>Siegesbeckialide I effectively suppresses LPS-induced NO production in RAW264.7 murine macrophages by directly interacting with IKKα/β.</p>Fórmula:C20H28O6Forma y color:SolidPeso molecular:364.43Ulevostinag
CAS:<p>Ulevostinag (MK-1454) is a STING agonist.</p>Fórmula:C20H22F2N10O9P2S2Forma y color:SolidPeso molecular:710.52STING agonist-28
CAS:<p>STING agonist-28 (CF510), a non-nucleotide, boosts STING, TBK1, IRF3 phosphorylation, and cytokines; active against SARS-CoV.</p>Fórmula:C39H46N14O6Forma y color:SolidPeso molecular:806.87HPK1-IN-58
HPK1-IN-58 is an inhibitor of HPK1 (IC50: 2.6 nM) and SLP76 (IC50: 20 nM). It enhances IL-2 secretion, thereby reversing PGE2-induced immunosuppression. HPK1-IN-58 is applicable for research in antitumor immunity.Fórmula:C26H30N8OForma y color:SolidPeso molecular:470.25426Redaporfin
CAS:<p>Redaporfin (F-2BMet, LUZ-11) is a PDT cancer photosensitizer; 83% of mice had tumor regression with 1.5 mg/kg and 74 J/cm² light.</p>Fórmula:C48H38F8N8O8S4Forma y color:SolidPeso molecular:1135.11Mifamurtide
CAS:<p>Mifamurtide is a drug against osteosarcoma, is an immunomodulator with antitumor effects.</p>Fórmula:C59H109N6O19PPureza:98%Forma y color:SolidPeso molecular:1237.5Reslizumab
CAS:<p>Reslizumab (Sch 55700) is a humanized immunoglobulin G (IgG) 4 κ monoclonal antibody, thereby reducing eosinophil production and survival.</p>Pureza:98.1% (SDS-PAGE); 98.6% (SEC-HPLC) - 98.1% (SDS-PAGE); 98.6% (SEC-HPLC)Forma y color:LiquidPeso molecular:N/AZL-1102
<p>ZL-1102 is a humanized monoclonal antibody inhibitor targeting interleukin-17A (IL-17A). SCH-900117 is being investigated for its potential use in the treatment of autoimmune diseases such as psoriasis and rheumatoid arthritis.</p>Forma y color:Odour LiquidFITC-labeled ODN 1826 sodium
<p>FITC-labeled ODN 1826 (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of CpG ODN cellular uptake and</p>Forma y color:Odour SolidPhotosensitizer-4
Compound PS-I (Photosensitizer-4) is an effective photosensitizer that can efficiently kill cancer cells and inhibit tumor growth under light exposure.Forma y color:Odour SolidSuc-Tyr-Val-Ala-Asp-pNA
CAS:<p>Suc-YVAD-pNA, a chromogenic caspase-1 substrate.</p>Fórmula:C31H38N6O12Forma y color:SolidPeso molecular:686.675IACS-8803 diammonium
<p>IACS-8803 diammonium, a potent cyclic dinucleotide STING agonist, demonstrates robust systemic antitumor efficacy [1].</p>Fórmula:C20H29FN12O9P2S2Forma y color:SolidPeso molecular:726.6BMX-010
CAS:<p>BMX-010, also known as AEOL-10113, is Porphyrin-Based SOD Mimic.</p>Fórmula:C48H44Cl5MnN8Forma y color:SolidPeso molecular:965.12FM101
<p>FM101 is a humanized monoclonal anti-IL6 antibody, suitable for use in asthma-related research.</p>Forma y color:Odour LiquidC-di-IMP disodium
<p>C-di-IMP disodium, a STING agonist, is utilized in tumor research [1].</p>Pureza:98%Forma y color:Odour Solid(-)-10,11-Dihydroxyfarnesol
CAS:<p>(-)-10,11-Dihydroxyfarnesol, from Cryptomarasmius aucubae, inhibits NO production.</p>Fórmula:C15H28O3Forma y color:SolidPeso molecular:256.38TLR7/8 agonist 4 TFA
CAS:<p>TLR7/8 agonist 4 TFA (compound 41) is a highly potent TLR7/8 agonist that exhibits significant anti-cancer activity.</p>Fórmula:C20H25F3N6O2Forma y color:SolidPeso molecular:438.45IKKγ NBD Inhibitory Peptide
CAS:<p>A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF</p>Fórmula:C170H259N49O42S1Pureza:98%Forma y color:SolidPeso molecular:3693.3Nrf2 activator-8
<p>Nrf2 Activator-8 (Compound 10e), with an EC50 of 37.9 nM, is a potent Nrf2 activator that demonstrates significant antioxidant and anti-inflammatory properties</p>Fórmula:C13H11ClN2O3SForma y color:SolidPeso molecular:310.76TP508
CAS:<p>TP508 (Chrysalin), a 23-amino-acid peptide from human prothrombin, aids in tissue repair, targeting thrombin receptors.</p>Fórmula:C97H146N28O36SPureza:98%Forma y color:SolidPeso molecular:2312.44DOPAL
CAS:<p>DOPAL, a neurotoxic aldehyde from dopamine metabolism, is linked to Parkinson's and can convert to DOPAC or DOPET.</p>Fórmula:C8H8O3Forma y color:SolidPeso molecular:152.15FITC-labeled Agatolimod sodium
<p>FITC-labeled Agatolimod (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of CpG ODN cellular uptake and</p>Forma y color:Odour SolidMAPK-IN-4
<p>MAPK-IN-4 (Compound c1) is an orally active anti-inflammatory agent that inhibits the expression and release of pro-inflammatory cytokines IL-6 and TNF-α induced by LPS. It interacts with IRAK4 to exert its anti-inflammatory effects by inhibiting the MAPK pathway.</p>Forma y color:Odour SolidROS inducer 6
<p>ROS inducer 6 (compound 9) acts as a reactive oxygen species (ROS) inducer by depleting intracellular glutathione, thereby functioning as an antitumor agent.</p>Fórmula:C32H26N2O3Forma y color:SolidPeso molecular:486.56Anti-MRC2/CD280 Antibody
<p>Anti-MRC2/CD280 Antibody is a humanized anti-MRC2/CD280 antibody that can be used in immunoblotting (WB) and immunohistochemistry experiments.</p>Pureza:99.1% (SDS-PAGE); 98.7% (SEC-HPLC) - 99.1% (SDS-PAGE); 98.7% (SEC-HPLC)Forma y color:Odour LiquidMifamurtide TFA
<p>Mifamurtide TFA: muramyl dipeptide analog, boosts immunity, activates macrophages/monocytes, potential osteosarcoma research.</p>Fórmula:C61H110F3N6O21PForma y color:SolidPeso molecular:1351.52Human Immunoglobulin M
<p>Human Immunoglobulin M (IgM) is an antibody secreted by the adaptive immune system in response to foreign antigens. It is a primary type of immunoglobulin released into circulation during the early stages of the primary antibody response. Human Immunoglobulin M forms a pentamer comprising five IgG equivalents, with 10 Fab fragments, allowing for 10 antigen binding sites. Additionally, Human Immunoglobulin M acts as a complement (complement) activator.</p>Forma y color:Odour SolidVemircopan
CAS:<p>Vemircopan is a complement factor D inhibitor.</p>Fórmula:C29H28BrN7O3Forma y color:SolidPeso molecular:602.493Dazostinag
CAS:<p>Dazostinag (TAK-676) is a STING agonist with anti-cancer properties, used in making ADCs.</p>Fórmula:C21H22F2N8O10P2S2Forma y color:SolidPeso molecular:710.52F-CRI1
<p>F-CRI1, a potent STING agonist with a dissociation constant (K d) of 40.62 nM, is an 18F-labeled radioactive probe employed for visualizing STING in the tumor</p>Fórmula:C23H25FN4O3Pureza:98%Forma y color:SolidPeso molecular:424.47Neuroprotective agent 8
<p>Neuroprotective agent 8 (compound AA-9) is an orally active neuroprotective agent that functions through antioxidant stress reduction and anti-inflammatory mechanisms. In a rat model of MCAO ischemic stroke, it activates PGC-1α and inhibits the NLRP3 inflammasome.</p>Forma y color:Odour SolidTBK1/IKKε-IN-6
CAS:<p>TBK1/IKKε-IN-6 (example 110) is a potent inhibitor of TBK1 and IKKε, with IC50 values of less than 100 nM for both enzymes.</p>Fórmula:C31H36F2N8O4Forma y color:SolidPeso molecular:622.678Chitoheptaose heptahydrochloride
CAS:<p>Chitoheptaose heptahydrochloride, a chitosan derivative, enhances wheat growth and photosynthesis, with health-protective traits.</p>Fórmula:C42H80ClN7O29Forma y color:SolidPeso molecular:1182.5717-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid
CAS:<p>DPA metabolite 17-oxo-DPA, found in fish oil, spurs antioxidant genes, modulates inflammation, and activates PPARγ (EC50 ≈ 200 nM).</p>Fórmula:C22H32O3Forma y color:SolidPeso molecular:344.495PSMA-DA1
CAS:PSMA–DA1 may be a useful PSMA-targeting radiotheranostic agent.Fórmula:C50H76IN9O20Forma y color:SolidPeso molecular:1250.105RC529-MDP
<p>RC529-MDP is an immunological adjuvant that couples Toll-like receptors (TLR4a) and NOD-like receptors (NOD2a) to enhance the innate immune response through the TLR4 and NOD2 signaling pathways. In mouse models, RC529-MDP induces high levels of the cytokine interleukin-related factor (IL-6), highlighting its immunostimulatory activity. Additionally, when injected into mice models with ovalbumin (OVA), RC529-MDP elevates OVA-specific antibody responses, T cell responses, and the proportion of memory T cells.</p>Fórmula:C118H215N10O28PForma y color:SolidPeso molecular:2252.99Bectumomab
CAS:<p>Bectumomab (IMMU-LL2) is a humanized IgG2a mAb targeting CD22, used in imaging and staging non-Hodgkin's lymphoma.</p>Forma y color:LiquidODN 2395
CAS:<p>ODN 2395, a class C oligodeoxynucleotide and TLR9 agonist, serves as a vaccine adjuvant. Its sequence is 5'-tcgtcgttttcggcgc:gcgccg-3' [1].</p>Forma y color:SolidPeso molecular:7035MRT67307
CAS:<p>Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy.</p>Fórmula:C26H36N6O2Pureza:99.25% - 99.84%Forma y color:SolidPeso molecular:464.6ATV006
CAS:<p>SHEN26 has antiviral activity and can be used in research on the treatment of viral infections.</p>Fórmula:C16H19N5O5Pureza:99.58%Forma y color:SolidPeso molecular:361.35SARS-CoV-2-IN-107
<p>SARS-CoV-2-IN-107 (Compound A7) is an inhibitor of SARS-CoV-2 3CLpro, with an IC50 of 261.3 nM. It inhibits the replication of SARS-CoV-2, exhibiting an EC50 of 11.7 μM. Additionally, SARS-CoV-2-IN-107 demonstrates anti-inflammatory activity in LPS-stimulated RAW264.7 macrophages, with a NO inhibition rate of 68.6%.</p>Fórmula:C15H11FO4Forma y color:SolidPeso molecular:274.244WAY-605471
CAS:WAY-605471 is a AHR antagonist with IC50 of 0.5 - 1 μM.Fórmula:C14H15NO3S2Pureza:99.62%Forma y color:SolidPeso molecular:309.4QX-005N
QX 005N is a humanized monoclonal anti-CD124/IL4R/IL-4Rα antibody. It is applicable in research related to asthma.Forma y color:Odour LiquidCL097
CAS:<p>CL097 activates TLR7/8, spurs macrophage cytokines, and enhances ROS creation with fMLF.</p>Fórmula:C13H14N4OPureza:99.88%Forma y color:SolidPeso molecular:242.28Factor B-IN-1
CAS:<p>Factor B-IN-1 is a Factor B inhibitor.</p>Fórmula:C19H16N4O2Forma y color:SolidPeso molecular:332.3559TLR8 agonist 8
CAS:<p>TLR8 agonist8 (Compound II-72) is an agonist of Toll-like receptor 8 (TLR8) with an EC50 of 0.25-1 μM. It demonstrates stability in both human and mouse plasma and induces the secretion of the cytokine TNFα with an EC50 of less than 1 μM. In the MC38-HER2 xenograft mouse model, TLR8 agonist8 exhibits antitumor activity, achieving a tumor growth inhibition (TGI) rate of 89%.</p>Fórmula:C53H63N11O10Forma y color:SolidPeso molecular:1014.14KTX-955
CAS:<p>KTX-955, a potent IRAK4 degrader, exhibits DC50 values of 5 nM for IRAK4 and 130 nM for Ikaros. It is primarily utilized in anticancer research [1] [2].</p>Fórmula:C46H51F3N8O7Forma y color:SolidPeso molecular:884.94Anti-osteoporosis agent-8
Anti-osteoporosis agent-8 (Compound 4aa) is a RANKL inhibitor, capable of preventing RANKL-induced osteoclastogenesis and osteoclast differentiation, with an IC50 of 2.41 μM. Furthermore, Anti-osteoporosis agent-8 has been shown to mitigate bone loss in an ovariectomized (OVX) mouse model.Fórmula:C18H19F3N2O2SePeso molecular:432.05638Mipeginterferon alfa-2b
CAS:<p>Mipeginterferon alfa-2b, an IFNA2b analogue, has 5 modified amino groups out of 11 and weighs 40 kDa.</p>Forma y color:LiquidNosantine racemate
CAS:Nosantine racemate is the racemate of Nosantine which is a IL-2 inducer or enhancer of IL-2 induction by phytohemagglutinin (PHA).Fórmula:C14H22N4O2Pureza:98%Forma y color:SolidPeso molecular:278.35Bavunalimab
CAS:<p>Bavunalimab: bispecific anti-CTLA-4/LAG-3 antibody, T-cell activator in NSG mice, for cancer research.</p>Forma y color:LiquidLadanetin-6-O-β-D-glucopyranoside
CAS:<p>Ladanetin-6-O-β-D-glucopyranoside, an active flavonoid, exhibits antioxidative effects and has potential for research into cardioprotective effects [1].</p>Fórmula:C22H22O11Forma y color:SolidPeso molecular:462.4His-Pro
CAS:<p>His-Pro is a dipeptide consisting of histidyl and proline.</p>Fórmula:C11H16N4O3Pureza:98%Forma y color:SolidPeso molecular:252.27LL-37 GKE acetate
<p>LL-37 GKE acetate, a peptide and active structural domain of LL-37, inhibits lps-induced vascular nitric oxide production,less toxic,antimicrobial，sepsis.</p>Fórmula:C121H206N38O30Pureza:99.88%Forma y color:SolidPeso molecular:2673.17TLR8 agonist 7
CAS:<p>TLR8 agonist7 is an agonist of Toll-like receptor 8 (TLR8) with an EC50 of less than 250 nM. It remains stable in human and mouse plasma and induces the secretion of the cytokine TNFα with an EC50 of less than 1 μM. In the MC38-HER2 xenograft mouse model, TLR8 agonist7 demonstrates antitumor activity, achieving a tumor growth inhibition (TGI) rate of 98%.</p>Fórmula:C54H63N9O16Forma y color:SolidPeso molecular:1094.13AHR Inhibitor I-103
CAS:<p>AHR Inhibitor I-103 is an aryl hydrocarbon receptor (AHR) inhibitor with anticancer activity used in the study of breast cancer and acute myeloid leukemia.</p>Fórmula:C21H17FN6Pureza:98.70%Forma y color:SoildPeso molecular:372.4Timosaponin E2
CAS:Timosaponin E2 is an anti-inflammatory agent that inhibits active oxygen production [1].Fórmula:C46H78O20Forma y color:SolidPeso molecular:951.1CDN-A
CAS:<p>CDN-A, a cyclic di-nucleotide, activates immune response & aids in ADC synthesis.</p>Fórmula:C22H29N11O12P2Forma y color:SolidPeso molecular:701.48PROTAC IRAK4 degrader-5
CAS:<p>PROTAC IRAK4 degrader-5 is a Cereblon-based IRAK4 degrader.</p>Fórmula:C41H40F3N11O9Forma y color:SolidPeso molecular:887.834Selnoflast calcium
CAS:<p>Selnoflast calcium (example 6), an NLRP3 inhibitor[1], is a chemical compound designed to suppress the activity of the NLRP3 inflammasome.</p>Fórmula:C20H29N3O3S·xCaPureza:98%Forma y color:SolidIVMT-Rx-3
<p>IVMT-Rx-3 is a chemical compound that serves as an inhibitor of SDCBP's targeting of the PDZ1 and PDZ2 domains of MDA-9/Syntenin.</p>Fórmula:C69H90F3N13O24Pureza:98%Forma y color:SoildPeso molecular:1542.54ATWLPPR Peptide TFA
<p>ATWLPPR Peptide TFA inhibits neuropilin-1 and VEGF165-NRP-1 binding; may reduce diabetic retinal damage.</p>Fórmula:C42H62F3N11O11Pureza:98%Forma y color:SolidPeso molecular:954c-di-AMP disodium
CAS:<p>c-di-AMP sodium: STING agonist, activates TBK3-IRF3 pathway, boosts type I IFN/TNF, regulates bacterial growth/virulence, and stimulates immune responses.</p>Fórmula:C20H22N10Na2O12P2Forma y color:SolidPeso molecular:702.38P2X7-IN-2 TFA
P2X7-IN-2 TFA inhibits IL-Iβ release (IC50=0.01nM), used in autoimmunity, inflammation & cardiovascular research.Fórmula:C24H22F7N3O4Forma y color:SolidPeso molecular:549.44KTX-612
CAS:<p>KTX-612 is a compound that serves as an orally active IRAK4 degrader, exhibiting a DC50 value of 7 nM. It is primarily utilized in oncology research [1].</p>Fórmula:C46H51F3N8O6Forma y color:SolidPeso molecular:868.94Glu-urea-Lys
CAS:Glu-urea-Lys is a molecular scaffold that targets PSMA and can be used as a prostate cancer imaging agent to study prostate-specific membrane antigens.Fórmula:C12H21N3O7Pureza:99.40%Forma y color:SolidPeso molecular:319.31Eritoran Tetrasodium
CAS:<p>Eritoran Tetrasodium, a TLR4 receptor antagonist, is used potentially for the treatment of type 2 diabetes.</p>Fórmula:C66H122N2Na4O19P2Pureza:98%Forma y color:SolidPeso molecular:1401.58Ezeprogind
CAS:<p>Ezeprogind, TLR9 inhibitor for Alzheimer's. Affordable Excellence: Reliable Quality You Can Trust</p>Fórmula:C25H44N6Pureza:99.28%Forma y color:SolidPeso molecular:428.66PMX 205 Trifluoroacetate
<p>PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR ; CD88 ) antagonist.</p>Fórmula:C47H63F3N10O8Forma y color:SolidPeso molecular:953.06SIN 14
<p>SIN 14 is an HO-1 activator that targets and activates HO-1 through an allosteric mechanism. Additionally, SIN 14 can induce the polarization of macrophages from the M1 phenotype to the M2 phenotype.</p>Fórmula:C20H22ClNO4Forma y color:SolidPeso molecular:375.12374Pegcetacoplan acetate
<p>Pegcetacoplan acetate is a pegylated complement C3 inhibitory peptide that functions by binding to complement component 3 (C3) and its activation fragment C3b. This compound is utilized in the study of complement-mediated diseases, including age-related macular degeneration, C3 glomerulopathy, geographic atrophy (GA), and autoimmune hemolytic anemia.</p>Forma y color:Odour SolidSTING agonist-27
CAS:<p>CF509 is a non-nucleotide STING agonist; it activates STING and combats SARS-CoV strains.</p>Fórmula:C40H50N14O6Forma y color:SolidPeso molecular:822.925-LOX/sEH-IN-1
<p>Compound 8o (5-LOX/sEH-IN-1) is a dual inhibitor with cardioprotective properties, targeting both 5-LOX and sEH with IC50 values of 3.05 μM and 2.20 nM respectively. It also inhibits the activity of COX-2 (IC50=10.50 μM). Possessing analgesic and anti-inflammatory properties, 5-LOX/sEH-IN-1 reduces ulcerogenicity, making it a potential candidate for developing anti-inflammatory agents with fewer gastrointestinal and cardiovascular side effects.</p>Forma y color:Odour SolidSARS-CoV-2-IN-39
CAS:<p>SARS-CoV-2-IN-39 is a SARS-CoV-2 inhibitor with an EC50 of 1 μM.</p>Fórmula:C14H8ClF4NO3Pureza:99.86%Forma y color:SoildPeso molecular:349.66STING agonist-24
CAS:CF504: non-nucleotide STING agonist, boosts STING, TBK1, IRF3 phosphorylation; raises IFN-β, IL-6, CXCL-10, TNF-α; active against SARS-CoV strains.Fórmula:C34H37N13O5Forma y color:SolidPeso molecular:707.74Tetrachlorohydroquinone
CAS:<p>TCHQ, a pentachlorophenol metabolite, toxic to trout liver cells, increases ROS, disrupts mitochondria, and causes necrosis in splenocytes. EC50: 1.55 μM.</p>Fórmula:C6H2Cl4O2Forma y color:SolidPeso molecular:247.89PSMA-trillium
CAS:PSMA-trillium is a PSMA-targeting compound comprising a PSMA-targeting molecule (PSMA binding agent), a Macropa chelator, and a pharmacokinetics-modulating group (PK modulator). It acts as the non-radioactive variant of Actinium-225-PSMA-Trillium (BAY 3563254), boasting enhanced PSMA targeting and pharmacokinetic properties. PSMA-trillium can bind with Ac through either the Macropa chelator or the radioactive isotope Actinium-225. Actinium-225-PSMA-Trillium effectively inhibits metastatic castration-resistant prostate cancer (mCRPC).Fórmula:C106H156IN17O34SPeso molecular:2371.44STING agonist-31
CAS:<p>STING agonist-31, a potent STING agonist, exhibits EC50 values of 0.24 μM and 39.51 μM for human STING (h-STING) and murine STING (m-STING), respectively,</p>Fórmula:C43H51N15O6Forma y color:SolidPeso molecular:873.96M0324
<p>M0324 is a MUC-1 conditional CD40 agonist composed of an anti-MUC-1 IgG and two identical CD40-targeting camelid VHH domains, selectively activate immune cells.</p>Forma y color:Odour LiquidBiotin-labeled ODN 2216 sodium
<p>Biotin-labeled ODN 2216 (sodium) serves as a specific agonist for human TLR9 (toll-like receptor 9), facilitating the assessment of CpG ODN cellular uptake and</p>Forma y color:Odour SolidRomilkimab
CAS:<p>Romilkimab (SAR156597) is a chimeric humanized immunoglobulin (Ig) antibody designed to specifically target interleukins 4 and 13 (IL-4 and IL-13) [1].</p>Forma y color:Liquid5(S),15(S)-DiHETE
CAS:<p>5(S),15(S)-DiHETE, made by 15-LO from 5(S)-HETE, boosts human PMNL degranulation via PAF, not fMLP/A23187/LTB4, and lures eosinophils at ED50 of 0.3μM.</p>Fórmula:C20H32O4Forma y color:SolidPeso molecular:336.472TLR7 agonist 17
CAS:TLR7 agonist 17 (compound 20) functions as a highly effective TLR7 agonist, exhibiting EC 50 values of 12 nM for hTLR7 and 17 nM for mTLR7. Additionally, this compound has demonstrated anticancer activity [1].Fórmula:C25H37N7O3Forma y color:SolidPeso molecular:483.61N-Acetyldopamine dimer-2
CAS:<p>Compound 2, an N-acetyldopamine dimer from Periostracum Cicadae, exhibits antioxidant and anti-inflammatory properties.</p>Fórmula:C20H20N2O6Forma y color:SolidPeso molecular:384.38Guignardone L
CAS:<p>Guignardone L, a metabolite extracted from the endophytic fungus Guignardia mangiferae, possesses toll-like receptor 3 (TLR3) regulating activity [1].</p>Fórmula:C17H24O4Forma y color:SolidPeso molecular:292.37Rabelomycin
CAS:<p>Rabelomycin is an angucycline group antibiotic.</p>Fórmula:C19H14O6Forma y color:SolidPeso molecular:338.31Anti-inflammatory agent 64
<p>Anti-inflammatory agent 64 (compound 4b) exhibits antioxidant and anti-inflammatory activities, effectively inhibiting the secretion of IL-6 and TNF-α while</p>Pureza:98%Forma y color:Odour SolidFM-303
<p>FM-303 is a monoclonal antibody inhibitor that targets interleukin-23 (IL-23). It shows promise for research in immune system and digestive system diseases.</p>Forma y color:Odour LiquidCD19 CAR circRNA
<p>CD19 CAR circRNA expresses a CD19 car protein for CAR-T immunotherapy targeting B-cell antigens.</p>Forma y color:SolidNOX4-IN-1
<p>NOX4-IN-1 (Compound 14m) is an inhibitor of NADPH oxidase 4 (NOX4) that reduces the production of reactive oxygen species (ROS). It also inhibits the TGF-β1/Smad signaling pathway, leading to decreased expression of fibrosis-related proteins. Additionally, NOX4-IN-1 impedes the migration of NRK-49F cells.</p>Fórmula:C26H16ClN3O3Forma y color:SolidPeso molecular:453.877DEPMPO-biotin
CAS:<p>DEPMPO is a stable nitrone for trapping O, N, S, C radicals, used in vivo/vitro with ESR. DEPMPO-biotin tags proteins' S-nitroso groups for analysis.</p>Fórmula:C24H42N5O8PSForma y color:SolidPeso molecular:591.66Croconazole
CAS:<p>Croconazole exhibited dose-dependent inhibitory activity on the 5-lipoxygenase (5-LOX) of neutrophils.</p>Fórmula:C18H15ClN2OPureza:99.71%Forma y color:SolidPeso molecular:310.78Biotinoyl tripeptide-1
CAS:<p>Biotinoyl tripeptide-1 can produce hair follicles by promoting scalp micro-circulation and reduce follicle atrophy and aging.</p>Fórmula:C24H38N8O6SPureza:98%Forma y color:SolidPeso molecular:566.67Balekafusp alfa
CAS:Balekafusp alfa is a human IgG1κ antibody targeting IL-2, known for its antitumor properties.Forma y color:LiquidSAP-04
<p>SAP-04 is a potent, orally active STING agonist exhibiting significant immunomodulatory effects appropriate for cancer therapy [1].</p>Fórmula:C24H30N6O4Pureza:98%Forma y color:SolidPeso molecular:466.533-(2-Hydroxyethyl) thio withaferin A
<p>3-(2-Hydroxyethyl) thio withaferin A, a steroidal lactone, blocks NF-kB, targets vimentin, and inhibits EPCR shedding.</p>Fórmula:C30H44O7SForma y color:SolidPeso molecular:548.732-Hydroxybenzylamine
CAS:<p>2-Hydroxybenzylamine captures IsoLGs, prevents early atrial fibrillation recurrence post-ablation.</p>Fórmula:C7H9NOPureza:95.93%Forma y color:CoaPeso molecular:123.15Anti-neuroinflammation agent 1
<p>Anti-neuroinflammation Agent 1 effectively modulates BV2 microglia cell polarization, shifting from an M1 to an M2 phenotype [1].</p>Fórmula:C22H20ClF6N3O3Pureza:98%Forma y color:SolidPeso molecular:523.86Selnoflast potassium
<p>Selnoflast (potassium) (example 6), is an NLRP3 inhibitor.</p>Fórmula:C20H29N3O3S·xKPureza:98%Forma y color:SolidDiplacol
CAS:<p>Diplacol, a geranylated flavanone isolated from Paulownia trees (Paulownia coreana UYEKI), exhibits anti-inflammatory properties by inhibiting NO production in LPS-stimulated Raw264.7 cells with an IC50 value of 4.53 μM [1].</p>Fórmula:C25H28O7Forma y color:SolidPeso molecular:440.49Anticonvulsant agent 10
<p>Anticonvulsant agent 10 (Compound 6d) is an inhibitor targeting the Keap1-Nrf2 interaction, with a strong activity showing an ED50 of 0.04 mmol/kg. By inhibiting the Keap1-Nrf2 binding, it activates the Nrf2/ARE pathway, providing anticonvulsant and neuroprotective effects, making it useful for research in epilepsy and neuroprotection.</p>Forma y color:Odour SolidOICR11029
CAS:<p>OICR11029 is a potent probe for Bcl-6.</p>Fórmula:C26H25Cl2N7O5Forma y color:SolidPeso molecular:586.427IRAK4-IN-25
<p>IRAK4-IN-25 (compound 38), a potent oral IRAK4 inhibitor (IC50 = 7.3 nM) with low clearance (Cl = 12 mL/min/kg), effectively suppresses pro-inflammatory</p>Fórmula:C23H25N5O4Pureza:98%Forma y color:SolidPeso molecular:435.484-Chlorochalcone
CAS:<p>4-Chlorochalcone is achalcone inhibit human MAO-B and ROS/RNS production and is able to inhibit the growth of CAL51 cells.</p>Fórmula:C15H11ClOPureza:98.08%Forma y color:SolidPeso molecular:242.7STING agonist-13
CAS:<p>STING agonist-13 boosts cancer immunity by activating STING pathway, reducing tumors, and enhancing immune memory.</p>Fórmula:C45H53N15O7Forma y color:SolidPeso molecular:916Anti-inflammatory agent 58
<p>Anti-inflammatory agent 58 exhibits IL-1β inhibition with an IC50 value of 1.08 μM and suppresses pro-inflammatory gene expression, protein secretion, and NF-κB</p>Forma y color:Odour SolidAmaroswerin
CAS:<p>Amaroswerin, a secoiridoid glucoside, has anti-inflammatory, antidiabetic, and other medicinal properties; it inhibits NO release at IC50 of 5.42 μg/mL.</p>Fórmula:C29H30O14Forma y color:SolidPeso molecular:602.54BRD5075
BRD5075 is an effective activator of GPR65, stimulating the production of cAMP in a GPR65-dependent manner. Additionally, it reduces the gene expression of IL-1, IL-2, TNF, and chemokines. BRD5075 holds potential for researching multiple sclerosis and inflammatory bowel disease (IBD).Forma y color:Odour SolidR1-ICR-5
CAS:<p>R1-ICR-5 is a selective PROTAC degrader targeting serine/threonine-protein kinase 1 (RIPK1). Mediated by VHL, R1-ICR-5 promotes the degradation of RIPK1, disrupting the TNFR1 and TLR3/4 signaling hubs, enhancing NF-κB, MAPK, and IFN signal output, and facilitating RIPK3 activation and necroptosis induction. R1-ICR-5 holds potential for research in cancer and inflammatory diseases.</p>Fórmula:C54H70N8O7S2Forma y color:SolidPeso molecular:1007.31Camstatin
CAS:An analog of PEP-19 with enhanced binding to and antagonism of calmodulin.Fórmula:C122H203N39O34Pureza:98%Forma y color:SolidPeso molecular:2760.19BCL6 PROTAC 1
CAS:<p>BCL6 PROTAC 1: Selective BCL6 degrader, IC50 8.8 µM, used in DLBCL research.</p>Fórmula:C45H52ClN9O12Forma y color:SolidPeso molecular:946.4AHR agonist 4
<p>AHR agonist 4 (compound 24e), as an Aryl hydrocarbon receptor (AHR) agonist, modulates the immune equilibrium between Th17/22 and Treg cells.</p>Fórmula:C14H10N4OSPureza:98%Forma y color:SolidPeso molecular:282.32(±)-Phrymarolin II
CAS:<p>(±)-Phrymarolin II is a promising class of inhibitors that targets the tobacco mosaic virus, representing a novel approach in plant virus suppression.</p>Fórmula:C23H22O10Forma y color:SolidPeso molecular:458.419COX-2/15-LOX-IN-4
<p>COX-2/15-LOX-IN-4 (compound 5i) is a dual inhibitor with IC50 values of 0.075 μM for COX-2 and 1.97 μM for 15-LOX.</p>Fórmula:C23H20FN3OSPureza:98%Forma y color:SolidPeso molecular:405.49TLQP-21
CAS:<p>TLQP 21, a VGF-derived peptide, guards CGCs against apoptosis and combats early diet-induced diabetes by boosting energy spend.</p>Fórmula:C107H170N40O26Pureza:98%Forma y color:SolidPeso molecular:2432.75Maritimetin
CAS:<p>Maritimein, an aurone from Coreopsis tinctoria, has potent antioxidant activity (IC50: 4.12 μM) and is used in cardiovascular research.</p>Fórmula:C15H10O6Forma y color:SolidPeso molecular:286.24NOD1 antagonist-1
<p>NOD1antagonist-1 (compound 37) acts as an antagonist to NOD1 and exhibits a slight selectivity between NOD1 and NOD2, with IC50 values of 9.18 μM and 20.8 μM, respectively.</p>Fórmula:C24H32N4O2SPeso molecular:440.2246Topramezone
CAS:<p>Topramezone is a 4-HPPD inhibitor herbicide for post-emergence weed control in corn.</p>Fórmula:C16H17N3O5SForma y color:SolidPeso molecular:363.39α-Guanidinoglutaric Acid
CAS:<p>α-Guanidinoglutaric Acid is found in cobalt-induced epileptogenic focus tissue in the cerebral cortex of cats.</p>Fórmula:C6H11N3O4Pureza:99.73%Forma y color:SolidPeso molecular:189.17LB244
<p>LB244, a homologue of BB-Cl-amidine, functions as an orally effective STING inhibitor with an EC50 value of 0.8 μM, applicable in the treatment of STING-</p>Fórmula:C30H27N5O5Pureza:98%Forma y color:SolidPeso molecular:537.573-Methoxycatechol
CAS:<p>3-Methoxycatechol: lignin-based, esophageal carcinogen. 1,2-Dihydroxy-3-methoxybenzene: potent anti-EMCV.</p>Fórmula:C7H8O3Pureza:99.31%Forma y color:SolidPeso molecular:140.145-LOX/NO-IN-1
<p>5-LOX/NO-IN-1 (Compound 7e) is a dual inhibitor of 5-LOX and nitric oxide release. It exhibits an IC50 value of 2.833 μM for 5-LOX and demonstrates anti-inflammatory properties.</p>Fórmula:C22H18N6O4Forma y color:SolidPeso molecular:430.42Crocin-4
CAS:<p>Crocin-4, a saffron carotenoid, is an antioxidant that inhibits Aβ deposits in the brain and may aid Alzheimer's research with anti-tumor effects.</p>Fórmula:C27H36O9Forma y color:SolidPeso molecular:504.576PROTAC IRAK4 degrader-6
CAS:<p>PROTAC IRAK4 degrader-6, potent, targets Cereblon to degrade IRAK4, detailed in US20190192668A1.</p>Fórmula:C42H41F3N12O8Forma y color:SolidPeso molecular:898.861CDD-3290
<p>CDD-3290 (Compound 20) is an inhibitor of prostate-specific antigen (PSA) with a Ki value of 216 nM. This compound also exhibits inhibitory effects on α-chymotrypsin and elastase.</p>Forma y color:Odour SolidClazakizumab
CAS:<p>Clazakizumab: monoclonal antibody targeting IL-6, may inhibit COVID-19 cytokine response, researched for PsA and renal rejection.</p>Forma y color:LiquidTri(TLR4-IN-C34-C2-amide-C3-amide-PEG1)-amide-C3-COOH
<p>Tri(TLR4-IN-C34) linker reduces inflammation by inhibiting TLR4 in cells, shown effective in mouse endotoxemia and enterocolitis.</p>Fórmula:C84H134N10O39Forma y color:SolidPeso molecular:1908.01RDR03785
CAS:<p>The MIF Antagonist IV, RDR 03785 controls the biological activity of MIF. This small molecule/inhibitor is primarily used for Cell Structure applications.</p>Fórmula:C19H18F3NO4Pureza:98.92%Forma y color:SolidPeso molecular:381.35Antibiofilm agent-8
<p>Antibiofilm agent-8 (compound Ru2) boosts antibacterial activity under visible light (400-700 nm, 10 J cm-2). It induces oxidative stress by promoting NADH oxidation and reactive oxygen species (ROS) generation, which disrupts the bacterial cell wall.</p>Fórmula:C35H23ClF6N7PRuPeso molecular:823.03887ARC186
<p>ARC186 is a highly potent aptamer that serves as a complement inhibitor by blocking the convertase-catalyzed activation of C5.</p>Forma y color:SolidPeso molecular:120702.76FAPI-46
CAS:<p>FAPI-46 is a radiotracer for fibroblast activation protein (FAP),conjugated with 68Ga or 177Lu tracer for FAP tumours in positron emission tomography (PET).</p>Fórmula:C41H57F2N11O9Forma y color:SolidPeso molecular:885.96ROS-ERS inducer 2
<p>ROS-ERS inducer 2 (Complex 3f) promotes the generation of intracellular ROS, affects mitochondrial function, facilitates the release of damage-associated molecular patterns (DAMPs), induces immunogenic cell death (ICD), and activates endoplasmic reticulum stress (ERS). It plays a significant role in anti-hepatocellular carcinoma research.</p>Fórmula:C24H23BrClF2N3PtForma y color:SolidPeso molecular:701.9QX006N
<p>QX006N is a humanized monoclonal antibody inhibitor targeting the human interferon α/β receptor 1 (IFNAR1). It is promising for research in systemic lupus erythematosus (SLE) and other IFNAR1-related autoimmune diseases.</p>Forma y color:Odour LiquidEX-A5758
CAS:<p>EX-A5758: novel nNOS-NOS1AP inhibitor, reduces pain & enhances paclitaxel's anti-tumor effect.</p>Fórmula:C10H17NO5Pureza:99.67%Forma y color:SolidPeso molecular:231.25ZSA-51
<p>ZSA-51 is an effective, orally active STING agonist with anticancer properties. It has the capability to remodel the immune microenvironment within tumors and lymph nodes.</p>Fórmula:C16H15NO6SForma y color:SolidPeso molecular:349.358Multiflorin B
CAS:<p>Multiflorin B (compound 5), a kaempferol glycoside, can be extracted from the root of Neocheiropteris palmatopedata.</p>Fórmula:C27H30O15Pureza:98%Forma y color:SolidPeso molecular:594.52Goflikicept
CAS:<p>Goflikicept (RPH 104) binds/inactivates IL-1ß/α; may research STEMI.</p>Forma y color:LiquidIRAK4-IN-26
<p>IRAK4-IN-26 (Compound 21), an IRAK4 inhibitor with an IC50 of 6.2 nM, exhibits an oral bioavailability of 21%.</p>Fórmula:C22H23N5O3Pureza:98%Forma y color:SolidPeso molecular:405.45GB1908
<p>GB1908 is a selective oral inhibitor of galectin-1 (galectin-1), with Ki values of 57 nM for human galectin-1 and 72 nM for mouse galectin-1. It demonstrates over 50-fold selectivity for galectin-1 compared to galectin-3. GB1908 can be utilized in lung cancer research.</p>Fórmula:C18H18Cl2N4O5S2Peso molecular:504.009573-(3-Methoxyphenyl)acrylic acid
CAS:<p>3-(3-Methoxyphenyl)acrylic acid can inhibit free radical generation, has antioxidant potential, and can be used in biochemical experiments and drug synthesis.</p>Fórmula:C10H10O3Pureza:99.91%Forma y color:SolidPeso molecular:178.19STING agonist-29
CAS:<p>CF511: non-nucleotide, small-molecule STING activator; fights SARS-CoV variants.</p>Fórmula:C38H44N14O6Forma y color:SolidPeso molecular:792.85NLRP3-IN-23
<p>NLRP3-IN-23 (Compound 15C) is an inhibitor that significantly impedes heme-mediated activation of the NLRP3 inflammasome at a concentration of 0.1 μM [1].</p>Pureza:98%Forma y color:Odour SolidcGAMP diammonium
<p>cGAMP is a second messenger that triggers interferon production via STING activation upon detecting cytosolic DNA.</p>Fórmula:C20H30N12O13P2Forma y color:SolidPeso molecular:708.47NLRP3-IN-15
CAS:<p>NLRP3-IN-15: potent, selective NLRP3 inflammasome inhibitor; IC50 0.114 μM for IL-1β; for inflammation research.</p>Fórmula:C22H19NO4Forma y color:SolidPeso molecular:361.39PMX 205
CAS:<p>PMX 205 is an effective complement antagonist of the C5a receptor.</p>Fórmula:C45H62N10O6Pureza:98%Forma y color:SolidPeso molecular:839.041-Hydroxy-ibuprofen
CAS:<p>1-Hydroxy Ibuprofen, a metabolite in P. australis, targets COX-1/COX-2 with IC50s: 13 μM/370 μM.</p>Fórmula:C13H18O3Forma y color:SolidPeso molecular:222.28027-epi Maresin 1
CAS:<p>7-epi Maresin 1 is the inactive 7(S) epimer of Maresin 1 , which contains a 7(R) hydroxyl group. It can be used as an experimental negative control.</p>Fórmula:C22H32O4Forma y color:SolidPeso molecular:360.494Reltecimod
CAS:Reltecimod, a CD28 antigen inhibitor, is used potentially for the treatment of necrotizing soft tissue infection.Fórmula:C46H72N10O15SPureza:98%Forma y color:SolidPeso molecular:1037.19dsVACV-70mer sodium
<p>dsVACV-70mer sodium is a 70 base pair double-stranded oligonucleotide that contains a viral DNA motif derived from vaccinia virus DNA. It effectively induces IFN-β through a STING-dependent mechanism.</p>TLR4-IN-C34-C2-amide-C6-OH
<p>TLR4-IN-C34-C2-amide-C6-OH: a linker with TLR4-IN-C34 that curbs TLR4 and inflammation in mice.</p>Fórmula:C25H42N2O11Forma y color:SolidPeso molecular:546.61EB-TCIP
<p>EB-TCIP (BAK-04-212) is a bivalent molecule composed of AP1867 and BI-3812. It facilitates the reversible formation of a ternary complex between FKBPF36V and BCL6BTB, thereby recruiting FKBP12F36V-tagged EWS/FLI1 to DNA sites bound by the transcriptional regulator BCL6, rapidly inducing expression of BCL6 target genes such as SOCS2 and CXCL11. EWS/FLI1 is a fusion transcription factor found in Ewing sarcoma. EB-TCIP is applicable for studying transcriptional dysregulation in cancer.</p>Forma y color:Odour SolidCTT2274
<p>CTT2274 is a prodrug of MMAE. It consists of a prostate-specific membrane antigen (PSMA) binding scaffold, a biphenyl motif, a pH-sensitive phosphoramidate linker, and an MMAE payload. CTT2274 selectively targets and binds to PSMA to deliver MMAE and has the capability to inhibit prostate cancer.</p>Fórmula:C119H159N17O33P2Forma y color:SolidPeso molecular:2417.58NLRP3-IN-76
<p>NLRP3-IN-76 is an orally active NLRP3 inhibitor that suppresses the production of NO and reduces the mRNA levels of pro-inflammatory cytokines (iNOS, IL-6, IL-1β, and TNFα). It exerts anti-inflammatory effects by inhibiting the activation of the NLRP3 inflammasome and the NF-κB signaling pathway. Furthermore, NLRP3-IN-76 can ameliorate DSS-induced colitis and is applicable for studying inflammatory bowel disease (IBD).</p>Forma y color:Odour SolidVensobafusp alfa
CAS:<p>Vensobafusp alfa (KP-104) is a fusion protein composed of an IgG4 monoclonal antibody targeting complement protein C5, combined with the domains 1-5 of complement factor H (FH1-5). It exhibits anti-inflammatory and immunomodulatory properties. The isotype control for Vensobafusp alfa can be referred to as human IgG4(S228P) kappa.</p>Forma y color:LiquidG3-C12
CAS:<p>G3-C12 shows anticancer activity. is a galectin-3 binding peptide, with Kd of 88 nM.</p>Fórmula:C74H115N23O23S2Pureza:98%Forma y color:SolidPeso molecular:1758.99Tuparstobart
CAS:<p>Tuparstobart (Incagn-02385) is an IgG1κ monoclonal antibody that targets the immune checkpoint receptor protein LAG-3, which is predominantly expressed on</p>Forma y color:LiquidZ-VRPR-FMK TFA
<p>Z-VRPR-FMK (TFA), a tetrapeptide, irreversibly inhibits MALT1, protecting against influenza A.</p>Fórmula:C33H50F4N10O8Forma y color:SolidPeso molecular:790.81TMX-201
CAS:<p>TMX-201: TLR7 ligand-phospholipid with potent immune-boosting effect; for breast cancer & melanoma study.</p>Fórmula:C57H93N6O12PForma y color:SolidPeso molecular:1085.36Cafestol palmitate
CAS:<p>Cafestol palmitate is an active compound found in green coffee beans. It can enhance the activity of glutathione S-transferase (GST) in mice and also exhibits weak COX-2 inhibitory activity.</p>Fórmula:C36H58O4Forma y color:SolidPeso molecular:554.843NLRP3-IN-14
CAS:<p>NLRP3-IN-14, potent selective NLRP3 inhibitor, KD 5.87μM; IC50 0.131μM for IL-1β; for inflammation research.</p>Fórmula:C27H28N2O4Forma y color:SolidPeso molecular:444.52Ibuprofen impurity 1
CAS:<p>Ibuprofen impurity 1: anti-inflammatory, inhibits COX-1/COX-2 with IC50s of 13 μM/370 μM.</p>Fórmula:C12H16O2Forma y color:SolidPeso molecular:192.258MLT-231
<p>MLT-231: potent MALT1 Inhibitor, IC50=9 nM; blocks BCL10 cleavage, IC50=160 nM; exhibits antitumor efficacy in mouse ABC-DLBCL model.</p>Forma y color:SolidMethyl 3,4-Dihydroxyphenylacetate
CAS:<p>Methyl 3,4-Dihydroxyphenylacetate is an effective enterovirus 71 (EV71) inhibitor, suppressing EV71 replication in rhabdomyosarcoma (RD) cells, antiviral.</p>Fórmula:C9H10O4Pureza:97.03%Forma y color:SolidPeso molecular:182.17β-Aminoarteether
CAS:<p>β-Aminoarteether (SM934 free base), an orally active derivative of Artemisinin, serves a pivotal role in the research of inflammation and autoimmune disorders,</p>Fórmula:C17H29NO5Pureza:96.09% - 97.02%Forma y color:SolidPeso molecular:327.427-O-Methylaloeasinol
CAS:<p>7-O-Methylaloeasinol is a useful organic compound for research related to life sciences. The catalog number is T126468 and the CAS number is 105317-69-9.</p>Fórmula:C20H26O9Forma y color:SolidPeso molecular:410.419C3a (70-77)
CAS:<p>C3a (70-77) is an octapeptide corresponding to the COOH terminus of C3a.</p>Fórmula:C35H61N13O10Pureza:98%Forma y color:SolidPeso molecular:823.94Sericin
<p>Sericin is a globular protein isolated from silkworm cocoons. It has cognitive enhancement and pain-relieving properties. Additionally, Sericin serves as a cryoprotectant, potentially replacing fetal bovine serum or dimethyl sulfoxide (DMSO). It helps reduce oxidative stress and reactive oxygen species (ROS). Sericin aids in wound repair by promoting collagen production and exhibits activities such as antioxidant, antidiabetic, antihyperlipidemic, anti-inflammatory, moisturizing, wound healing promotion, antibacterial, and antitumor effects.</p>Forma y color:Odour Solid3′-Hydroxy-4′-O-methylglabridin
CAS:<p>3′-Hydroxy-4′-O-methylglabridin effectively prevents NADH-dependent peroxidation, exhibiting potent antioxidant properties [1].</p>Fórmula:C21H22O5Forma y color:SolidPeso molecular:354.4EC1169
CAS:<p>EC1169 is a targeted PSMA ligand that acts to inhibit the proliferation of cells expressing PSMA.</p>Fórmula:C78H112N14O28S3Forma y color:SolidPeso molecular:1790.00Iromycin A
CAS:<p>Iromycin A: a bacterial metabolite inhibiting NOS III over NOS I, blocks NADH oxidation, IC50 = 0.461 µM.</p>Fórmula:C19H29NO2Forma y color:SolidPeso molecular:303.44Zomiradomide
CAS:<p>Zomiradomide is a PROTAC degradation agent targeting IRAK4,oral, Ikaros (IKZF1) and Aiolos (IKZF3), NF-κB type I interferon, B-cell lymphoma.</p>Fórmula:C45H48F3N7O6SPureza:98.41%Forma y color:SolidPeso molecular:871.97ROS-ERS inducer 1
<p>Type II ICD agent, ROS-ERS inducer 1, is a Pt(II)-NHC from 4,5-diarylimidazole, boosting ER stress, ROS, and DAMPs in HCC, outperforming Cisplatin.</p>Fórmula:C24H23F2I2N3PtForma y color:SolidPeso molecular:840.35Anti-Mouse MHC Class I (H-2) Antibody (M1/42.3.9.8)
Anti-Mouse MHC Class I (H-2) Antibody (M1/42.3.9.8) is a rat-derived IgG2a, κ antibody inhibitor specifically targeting mouse MHC Class I.AJ2-30
CAS:AJ2-30: Inhibits SLCl5A4, TLR9-B cell activation, MDP transport, NOD signaling; for inflammation study.Fórmula:C23H22N4Pureza:>99.99%Forma y color:SoildPeso molecular:354.45Pepinh-MYD TFA
<p>Pepinh-MYD TFA is a MyD88 inhibitor that features domain sequences from MyD88TIR and a protein transduction sequence, allowing it to penetrate cell membranes. By disrupting MyD88-mediated TLR pathway signaling, it inhibits related immune responses. Pepinh-MYD TFA shows potential for investigating MyD88's role in viral infections.</p>Fórmula:C151H248N50O35S2·xC2HF3O2Forma y color:SolidPeso molecular:3388.03 (free base)
