Inmunología e inflamación
Los inhibidores de inmunología e inflamación son compuestos que modulan la respuesta inmunitaria y los procesos inflamatorios. Estos inhibidores son cruciales para estudiar los mecanismos de regulación inmunitaria, la autoinmunidad y la inflamación crónica, así como para desarrollar tratamientos para enfermedades inflamatorias, alergias y trastornos relacionados con el sistema inmunológico. Al dirigirse a vías clave en el sistema inmunológico, estos inhibidores pueden ayudar a reducir las respuestas inmunitarias excesivas o inadecuadas. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad para apoyar su investigación en inmunología, inflamación y desarrollo terapéutico.
Subcategorías de "Inmunología e inflamación"
- CCR(136 productos)
- CXCR(148 productos)
- Pared celular(5 productos)
- Receptor de IL(112 productos)
- IκB / IKK(60 productos)
- LTR(3 productos)
- MALT(23 productos)
- MRP(6 productos)
- NADPH-oxidasa(1 productos)
- NF-κB(444 productos)
- NOD(17 productos)
- NOS(63 productos)
- Nrf2(79 productos)
- PGE sintasa(31 productos)
- ROS(69 productos)
- TGF-beta / Smad(58 productos)
- TLR(66 productos)
- Tiorredoxina(12 productos)
- gp120 / CD4(4 productos)
Mostrar 11 subcategorías más
Se han encontrado 3045 productos de "Inmunología e inflamación"
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RIPK1-IN-25
<p>RIPK1-IN-25 (WL8) is a RIPK1 inhibitor with blood-brain barrier permeability, displaying an EC50 of 19.9 nM and a Kd of 25 nM. It is utilized in the research of neurodegenerative diseases.</p>Forma y color:Odour SolidSTING-IN-6
CAS:<p>STING-IN-6 (compound 50), a potent inhibitor of STING, exhibits a pIC50 value of 8.9, indicating its significant inhibitory capacity.</p>Fórmula:C46H52N12O6Forma y color:SolidPeso molecular:868.98Tri(TLR4-IN-C34-PEG2-amide-PEG1)-amide-C3-COOH
<p>Tri(TLR4-IN-C34-PEG2/PEG1)-amide-C3-COOH is a TLR4 inhibiting linker, reducing inflammation in endotoxemia and enterocolitis mouse models.</p>Fórmula:C78H125N7O42Forma y color:SolidPeso molecular:1832.85Antiparasitic agent-26
<p>Antiparasitic agent-26 (Compound 8) is an antiparasitic compound that effectively inhibits the growth of Naegleria fowleri, with an IC50 of 22.87 μM (trophozoite stage) and 25.16 μM (cyst stage). It exerts its antiparasitic effects by inducing programmed cell death, which includes cytosolic calcium accumulation, mitochondrial membrane potential collapse, ATP synthesis inhibition, ROS accumulation, and chromatin condensation. Antiparasitic agent-26 can be utilized in research on primary amoebic meningoencephalitis (PAM).</p>Forma y color:Odour SolidNLRP3-IN-48
<p>NLRP3-IN-48 is an inhibitor of NLRP3. It suppresses the activation of the NLRP3 inflammasome by targeting the NLRP3 protein, thereby interfering with the assembly of the NLRP3 inflammasome. Additionally, NLRP3-IN-48 exhibits anti-inflammatory activity in a DSS-induced acute colitis model in mice.</p>Forma y color:Odour SolidPegaldesleukin
CAS:<p>Pegaldesleukin, a PEG-IL2 conjugate, exhibits antiviral properties, potentially slowing HIV progression, preserving immune function.</p>Forma y color:LiquidBMS-986179
<p>BMS-986179 is a human monoclonal antibody targeting NT5E/CD73. It inhibits CD73 enzymatic activity both in tumor vasculature and tumor cells. BMS-986179 is applicable for research in advanced solid tumors.</p>Forma y color:Odour LiquidIL-6-IN-1
<p>IL-6-IN-1 (Compound 22) inhibits the release of IL-6 with an IC50 of 1.065 μM and demonstrates anti-inflammatory activity in LPS-induced acute lung injury in mice.</p>Fórmula:C16H12N2OSForma y color:SolidPeso molecular:280.34Antibacterial agent 119
<p>Antibacterialagent 119 (Compound 21 g) is a potential antibacterial agent effective against methicillin-resistant Staphylococcus aureus, with a minimum inhibitory concentration (MIC) of less than 1 μg/mL against tested strains. It induces reactive oxygen species (ROS) generation and disrupts bacterial cell membranes, causing their rupture. Antibacterialagent 119 exhibits strong antimicrobial activity, low cytotoxicity, rapid bactericidal action, and favorable in vivo antibacterial efficacy.</p>Fórmula:C42H54BrClN2O4Forma y color:SolidPeso molecular:766.246HNGF6A
CAS:<p>increases glucose stimulated insulin secretion and glucose metabolism</p>Fórmula:C112H198N34O31S2Pureza:98%Forma y color:SolidPeso molecular:2581.11GSK1795091
CAS:<p>GSK1795091, a synthetic TLR4 agonist, boosts immunity and shows antitumor effects, enhancing flu vaccine response.</p>Fórmula:C81H157N2O16PForma y color:SolidPeso molecular:1446.119c-di-AMP disodium
CAS:<p>c-di-AMP sodium: STING agonist, activates TBK3-IRF3 pathway, boosts type I IFN/TNF, regulates bacterial growth/virulence, and stimulates immune responses.</p>Fórmula:C20H22N10Na2O12P2Forma y color:SolidPeso molecular:702.38Butan-1-amine hydrochloride
CAS:<p>1-Butylamine hydrochloride,butylamine, a potential agonist of Nrf2/ARE (Nuclear Factor Erythroid 2 Associated Factor 2/Antioxidant Response Element).</p>Fórmula:C4H12ClNForma y color:SolidPeso molecular:109.6AMY-101
CAS:<p>AMY-101 TFA is a C3 complement inhibitor with high affinity (KD: 0.5 nM) and promising anti-inflammatory effects in severe COVID-19.</p>Fórmula:C83H117N23O18S2Pureza:98%Forma y color:SolidPeso molecular:1789.111-Ethoxycarbonyl-β-carboline
CAS:<p>1-Ethoxycarbonyl-β-carboline is a natural product for research related to life sciences. The catalog number is TN7072 and the CAS number is 72755-19-2.</p>Fórmula:C28H23N4O4Forma y color:SolidPeso molecular:479.516Eramkafusp Alfa
<p>Eramkafusp alfa is a human IgG1 antibody that targets the murine B lymphocyte antigen CD20, also known as MS4A1 [1].</p>Forma y color:Odour LiquidMifamurtide
CAS:<p>Mifamurtide is a drug against osteosarcoma, is an immunomodulator with antitumor effects.</p>Fórmula:C59H109N6O19PPureza:98%Forma y color:SolidPeso molecular:1237.5iE-DAP dihydrochloride
<p>iE-DAP dihydrochloride is a Nod1 agonist that activates the NF-κB pathway through recognition by Nod1, leading to an inflammatory cytokine response. This compound is useful for studying maternal-fetal inflammation and preterm birth.</p>Fórmula:C12H23Cl2N3O7Forma y color:SolidPeso molecular:391.09131STING agonist-28
CAS:<p>STING agonist-28 (CF510), a non-nucleotide, boosts STING, TBK1, IRF3 phosphorylation, and cytokines; active against SARS-CoV.</p>Fórmula:C39H46N14O6Forma y color:SolidPeso molecular:806.87Sirtuin modulator 2
CAS:<p>Sirtuin modulator 2 (N-(3-(imidazo[2,1-b]thiazol-6-yl)phenyl)-2-methoxybenzamide) exhibits antidiabetic, anti-inflammatory and antitumor activities.</p>Fórmula:C19H15N3O2SPureza:99.67%Forma y color:SolidPeso molecular:349.41Salicortin
CAS:<p>Salicortin, a phenolic glycoside from Populus and Salix, has anti-adipogenic, anti-amnesic, and immune effects.</p>Fórmula:C20H24O10Pureza:98%Forma y color:SolidPeso molecular:424.40IACS-8803 diammonium
<p>IACS-8803 diammonium, a potent cyclic dinucleotide STING agonist, demonstrates robust systemic antitumor efficacy [1].</p>Fórmula:C20H29FN12O9P2S2Forma y color:SolidPeso molecular:726.6EPI-589
CAS:<p>EPI-589, a quinone oxidoreductase inhibitor, may treat ALS; it's safe and tolerable.</p>Fórmula:C14H19NO4Pureza:98%Forma y color:SolidPeso molecular:265.31SMRT peptide
CAS:SMRT peptide, one of the corepressor factors interacting with the BCL6 BTB domain, binds to the BTB domain of BCL6 to enhance its transcriptional repression function. Additionally, SMRT peptide is utilized for studying protein-protein interactions.Fórmula:C82H142N26O24Forma y color:SolidPeso molecular:1876.16IKK-IN-3
CAS:<p>IKK-IN-3: potent IKK2 inhibitor (IC50=19nM), affects IKK1(IC50=400nM).</p>Fórmula:C17H17N5SForma y color:SolidPeso molecular:323.42Guretolimod
CAS:<p>Guretolimod is a Toll-like receptor 7 (TLR7) agonist.</p>Fórmula:C24H34F3N5O4Forma y color:SolidPeso molecular:513.562Ac-LDEETGEFL-NH2
CAS:<p>Ac-LDEETGEFL-NH2 is a fluorescent molecule designed to target the interaction between the Kelch-like ECH-associated protein 1 (Keap1) and nuclear factor</p>Fórmula:C48H72N10O19Forma y color:SolidPeso molecular:1093.14Allyl methyl trisulfide
CAS:<p>Allyl methyl trisulfide: a garlic oil compound with antibacterial, antioxidant, and antitumor properties.</p>Fórmula:C4H8S3Forma y color:SolidPeso molecular:152.3FITC-labeled ODN TTAGGG sodium
<p>FITC-labeled ODN TTAGGG (sodium) is an inhibitory oligonucleotide that functions as an antagonist of TLR9, AIM2, and cGAS.</p>Forma y color:Odour SolidArginase inhibitor 7
CAS:<p>Arginase Inhibitor 7 (compound A17), an inhibitor of arginase (ARG1), exhibits an IC 50 value of 0.16 μM and possesses high oral bioavailability [1].</p>Fórmula:C14H29BN6O5Forma y color:SolidPeso molecular:372.23Polyinosinic acid
CAS:<p>Polyinosinic acid: single-strand, TLR3 agonist, boosts immune response, has immune regulation uses.</p>Fórmula:(C10H13N4O8P)xForma y color:SolidSTING agonist-24
CAS:<p>CF504: non-nucleotide STING agonist, boosts STING, TBK1, IRF3 phosphorylation; raises IFN-β, IL-6, CXCL-10, TNF-α; active against SARS-CoV strains.</p>Fórmula:C34H37N13O5Forma y color:SolidPeso molecular:707.74MJ210
<p>MJ210 is an orally active and blood-brain barrier-permeable modulator of the NF-κB and MAPK pathways, exhibiting neuroprotective properties. In vitro, 5 μM MJ210 can increase the survival rate of rotenone-treated SH-SY5Y cells to 81.9% and reduce levels of ROS. In vivo, 5 mg/kg MJ210 improves motor dysfunction in rat models of Parkinson's disease. MJ210 is useful for research in neurological disorders, including Parkinson's disease.</p>Forma y color:Odour SolidSepteremophilane E
<p>Septeremophilane E, from Septoria rudbeckiae fungus, inhibits NO production.</p>Fórmula:C21H26O5Forma y color:SolidPeso molecular:358.43MUC1, mucin core
CAS:<p>MUC1: Type I transmembrane glycoprotein, overexpressed and abnormally glycosylated in cancer, binds ICAM-1 domain 1.</p>Fórmula:C61H101N19O24Forma y color:SolidPeso molecular:1484.588KYN-101
CAS:<p>KYN-101 is an and aryl hydrocarbon receptor (AHR) inhibitor with anticancer activity. KYN-101 is used for the study of breast cancer and acute myeloid leukemia.</p>Fórmula:C22H19FN6Pureza:98.35%Forma y color:SolidPeso molecular:386.43MCI
<p>MCI, a chemical compound demonstrating significant anti-inflammatory effects, particularly in collagen-induced arthritis (CIA) models, modulates inflammation</p>Fórmula:C45H52ClN7O13Pureza:98%Forma y color:SolidPeso molecular:934.39CAY10657
CAS:<p>CAY10657 has a wide range of applications in life science related research.</p>Fórmula:C17H20N4O3SForma y color:SolidPeso molecular:360.43cGAMP disodium
CAS:<p>cGAMP disodium, a bacterial CDN, boosts interferon production and activates STING, enhancing immune responses as a sublingual adjuvant.</p>Fórmula:C20H24N10O13P2·2NaForma y color:SoildPeso molecular:720.39KRN7000 analog 1
<p>KRN7000 analog 1 stimulates a strong Th1-biased immune response by inducing interferon-γ (IFN-γ) and reducing interleukin-4 (IL-4). This compound shows potential as an antitumor agent and vaccine adjuvant.</p>Fórmula:C47H76FNO9SPeso molecular:849.52248Anti-osteoporosis agent-8
Anti-osteoporosis agent-8 (Compound 4aa) is a RANKL inhibitor, capable of preventing RANKL-induced osteoclastogenesis and osteoclast differentiation, with an IC50 of 2.41 μM. Furthermore, Anti-osteoporosis agent-8 has been shown to mitigate bone loss in an ovariectomized (OVX) mouse model.Fórmula:C18H19F3N2O2SePeso molecular:432.05638RGB097
<p>RGB097 is an efficacious inhibitor of D-dopachrome tautomerase (D-DT), with an IC50 value of 0.5 µM. It holds potential for applications in cancer research.</p>Fórmula:C26H22F3N5O3Peso molecular:509.16747Phytoene desaturase-IN-1
CAS:<p>Potent PDS inhibitor with Kd of 65.9 μM, induces mRNA reduction and ROS accumulation, useful in agriculture.</p>Fórmula:C18H13ClF3N3O2SForma y color:SolidPeso molecular:427.83Valeriandoid F
CAS:<p>Valeriandoid F, an iridoid, strongly inhibits NO production (IC50: 0.88 μM) and has anti-inflammatory, antiproliferative effects.</p>Fórmula:C23H34O9Forma y color:SolidPeso molecular:454.516Feeblin
CAS:<p>Feeblin (IRF5-IN-1) induces protein degradation, inhibits pro-inflammatory pathways, and is used for autoimmune disease research.</p>Fórmula:C27H33N3O2Pureza:99.58% - 99.88%Forma y color:SoildPeso molecular:431.57Anti-inflammatory agent 93
<p>Compound 2g (Anti-inflammatory agent 93) is an active compound that exhibits analgesic activity.</p>Fórmula:C27H17Cl2N3O2Forma y color:SolidPeso molecular:486.35InsB (9-23)
CAS:<p>InsB (9-23) (InsulinB chain (9-23)) is an insulin B chain peptide capable of binding to the class II major histocompatibility complex (MHC) allele I-Ag7. It holds potential for research into various autoimmune diseases, including type 1 diabetes.</p>Fórmula:C72H116N20O22SPeso molecular:1645.88NC318
<p>NC318 is a humanized antibody targeting Siglec-15/CD33L3 for the study of non-small cell lung cancer.</p>Pureza:98.6% (SDS-PAGE); 99% (SEC-HPLC) - 98.6% (SDS-PAGE); 99% (SEC-HPLC)Forma y color:Odour LiquidCOX-2/15-LOX-IN-2
<p>COX-2/15-LOX-IN-2 is a potent inhibitor of both COX-2 and 15-LOX, demonstrating IC50 values of 0.065 μM for COX-2 and 1.86 μM for 15-LOX.</p>Fórmula:C27H26N6OS2Pureza:98%Forma y color:SolidPeso molecular:514.66APF
CAS:<p>APF, a low-fluorescence probe, turns bright (490/515 nm) when oxidized by specific radicals; not affected by NO or H2O2.</p>Fórmula:C26H17NO5Forma y color:SolidPeso molecular:423.42
