Inmunología e inflamación
Los inhibidores de inmunología e inflamación son compuestos que modulan la respuesta inmunitaria y los procesos inflamatorios. Estos inhibidores son cruciales para estudiar los mecanismos de regulación inmunitaria, la autoinmunidad y la inflamación crónica, así como para desarrollar tratamientos para enfermedades inflamatorias, alergias y trastornos relacionados con el sistema inmunológico. Al dirigirse a vías clave en el sistema inmunológico, estos inhibidores pueden ayudar a reducir las respuestas inmunitarias excesivas o inadecuadas. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad para apoyar su investigación en inmunología, inflamación y desarrollo terapéutico.
Subcategorías de "Inmunología e inflamación"
- CCR(140 productos)
- CXCR(153 productos)
- Pared celular(5 productos)
- Receptor de IL(109 productos)
- IκB / IKK(59 productos)
- LTR(3 productos)
- MALT(25 productos)
- MRP(6 productos)
- NADPH-oxidasa(1 productos)
- NF-κB(446 productos)
- NOD(17 productos)
- NOS(62 productos)
- Nrf2(82 productos)
- PGE sintasa(31 productos)
- ROS(70 productos)
- TGF-beta / Smad(59 productos)
- TLR(76 productos)
- Tiorredoxina(12 productos)
- gp120 / CD4(4 productos)
Mostrar 11 subcategorías más
Se han encontrado 3304 productos de "Inmunología e inflamación"
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α-Guanidinoglutaric Acid
CAS:α-Guanidinoglutaric Acid is found in cobalt-induced epileptogenic focus tissue in the cerebral cortex of cats.Fórmula:C6H11N3O4Pureza:99.73%Forma y color:SolidPeso molecular:189.17Hydroxychloroquine Impurity E
CAS:Hydroxychloroquine Impurity E, a byproduct, can block TLR7/9 and inhibit SARS-CoV-2 in vitro.Fórmula:C14H17ClN2OForma y color:SolidPeso molecular:264.75Pratensein
CAS:Pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells.Fórmula:C16H12O6Pureza:99.90%Forma y color:SolidPeso molecular:300.26POT-4 acetate
<p>POT-4 acetate inhibits Complement C3 activation. POT-4 acetate can be used for studies about age-related macular degeneration.</p>Fórmula:C74H106N22O20S2Pureza:98%Forma y color:SolidPeso molecular:1687.9Ac-macropa
Ac-macropa is a conjugate of Actinium-225 that targets PSMA, and it is useful for researching prostate cancer.Fórmula:C39H52AcN6O9SPeso molecular:1007.3794Maresin 2
CAS:<p>Maresin 2 (3R,14S-diHDHA) is a specialized pro-ablative lipid mediator with anti-inflammatory and analgesic activity that promotes mucosal repair.</p>Fórmula:C22H32O4Forma y color:SolidPeso molecular:360.49hSTING activator-1
<p>hSTING activator-1 (Compound 68) is a STING agonist capable of effectively activating various human STING variants (R232, H232, HAQ), with EC50 values of 56 nM, 89 nM, and 51 nM, respectively. This compound activates the type I interferon pathway by directly binding to the STING protein and stabilizing its conformation, which leads to downstream IRF3 phosphorylation and cytokine release. hSTING activator-1 also demonstrates potential in cancer research by inhibiting fibrosarcoma tumor growth.</p>Forma y color:Odour SolidRedaporfin
CAS:Redaporfin (F-2BMet, LUZ-11) is a PDT cancer photosensitizer; 83% of mice had tumor regression with 1.5 mg/kg and 74 J/cm² light.Fórmula:C48H38F8N8O8S4Forma y color:SolidPeso molecular:1135.11TLR4-IN-C34-C2-amide-C6-OH
TLR4-IN-C34-C2-amide-C6-OH: a linker with TLR4-IN-C34 that curbs TLR4 and inflammation in mice.Fórmula:C25H42N2O11Forma y color:SolidPeso molecular:546.61NLRP3-IN-73
NLRP3-IN-73 (W16) is an orally bioavailable inhibitor that disrupts the assembly of the NLRP3 inflammasome, exhibiting an IC50 value of 0.18 μM for the NLRP3/IL-1β pathway.Forma y color:Odour SolidBiotin-labeled ODN TTAGGG sodium
<p>Biotin-labeled ODN TTAGGG (sodium) is an inhibitory oligonucleotide (ODN) that functions as an antagonist to TLR9, AIM2, and cGAS.</p>Forma y color:Odour SolidMC4762
MC4762 is an inhibitor of NOX2 and MAOB, with IC50 values of 0.155 μM and 0.182 μM, respectively. It exhibits anti-inflammatory properties by suppressing the production of ROS and downregulating the expression of pro-inflammatory cytokines such as iNOS, IL-1β, and IL-6.Forma y color:Odour SolidMik-β-1
Mik-Beta-1 is a human IgG1-kappa monoclonal antibody targeting IL2RB. For isotype control, refer to Human IgG1 kappa, Isotype Control. Mik-Beta-1 is applicable in research related to the prevention of allograft rejection.Forma y color:Odour LiquidKetoprofen L-thyroxine ester
Ketoprofen L-thyroxine ester, a prodrug of ketoprofen, acts as a reservoir to slowly release ketoprofen in the brain [1].Forma y color:Odour SolidGHN105
<p>GHN105 is an orally active STING inhibitor that suppresses STING-dependent IFN-β secretion in THP-1 human monocytes with an IC50 of 4.4 μM. In mice, GHN105 reduces serum levels of IFN-β, IL-6, and CXCL10, and alleviates colitis in a DSS-induced acute colitis mouse model. Additionally, GHN105 demonstrates favorable pharmacokinetic properties in mice, with an oral bioavailability of 43% and a half-life of 1.1 hours.</p>Fórmula:C41H56N2O14Forma y color:SolidPeso molecular:800.89Efmarodocokin alfa
CAS:Efmarodocokin alfa, IL-22/IgG4 fusion protein, activates IL-22 pathways, researched for severe COVID-19 pneumonia.Forma y color:Liquid3-Hydroxykynurenamine
CAS:3-Hydroxykynurenamine (3-HKA) is a tryptophan metabolite with anti-inflammatory effects, reducing cytokines and aiding in models of psoriasis and nephritis.Fórmula:C9H12N2O2Forma y color:SolidPeso molecular:180.2Prifelone
CAS:Prifelone (R 830) is a non-steroidal anti-inflammatory compound with antioxidant activity.Fórmula:C19H24O2SPureza:99.8%Forma y color:SolidPeso molecular:316.46Inflexuside B
CAS:<p>Inflexuside B, an abietane diterpenoid derived from the aerial parts of Isodon inflexus, effectively inhibits lipopolysaccharide (LPS)-activated NO Synthase in</p>Fórmula:C35H48O11Forma y color:SolidPeso molecular:644.75Amphimedine
CAS:<p>Amphimedine is a Pyridoacridine Marine Alkaloid.</p>Fórmula:C19H11N3O2Forma y color:SolidPeso molecular:313.31RH-EDA
<p>RH-EDA, a rhodamine-based turn-on fluorescent probe, detects hydroxyl radicals ([OH]) in living systems.</p>Fórmula:C28H25N3O4Forma y color:SolidPeso molecular:467.52IFN-α Receptor Recognition Peptide 1
CAS:IFN-α Receptor Recognition Peptide 1, associated with receptor interactions, is a peptide of IFN-α.Fórmula:C35H59N13O12SPureza:98%Forma y color:SolidPeso molecular:885.99Perfluorohexane
CAS:Perfluorohexane (AF-0150) is a perfluorocarbon (PFC)-based microbubble formulation for ultrasound contrast and is developmentally toxic.Fórmula:C6F14Pureza:98%Forma y color:Colourless LiquidPeso molecular:338.04Keap1-Nrf2-IN-27
<p>Keap1-Nrf2-IN-27 is an inhibitor of the Keap1-Nrf2 protein-protein interaction (PPI) with a KD2 value of 0.119 μM. It suppresses the expression of pro-inflammatory cytokines TNF-α and IL-6 in an LPS-induced RAW264.7 cell model.</p>Forma y color:Odour SolidC2 Protein (human)
C2 Protein (human) is a naturally glycosylated peptide with a 20-amino acid signal sequence. It plays a critical regulatory role in the early activation stages of the classical pathway and is involved in the formation of the classical pathway C3 convertase, C4b2a.Forma y color:Odour SolidAntifungal agent 123
<p>Antifungalagent 123 (Compound 4b) demonstrates strong affinity for the oxidoreductase of Staphylococcus aureus or membrane proteins of Candida albicans, exhibiting both antibacterial and antifungal properties. Additionally, it is capable of scavenging free radicals, showcasing antioxidant effects. Antifungalagent 123 also inhibits the TLR signaling pathway and possesses anti-inflammatory activity.</p>Fórmula:C21H20N4O3Forma y color:SolidPeso molecular:376.409CNTO4088
CNTO4088 is a monoclonal antibody inhibitor that targets interleukin-23 (IL-23). It holds potential for research in autoimmune diseases such as psoriasis and rheumatoid arthritis.Forma y color:Odour LiquidDibenzothiophene
CAS:<p>Dibenzothiophene, a sulfur PAH in petroleum, has 3 rings and keratolytic properties.</p>Fórmula:C12H8SPureza:99.82%Forma y color:Yellow To Green SolidPeso molecular:184.26PSMA-ALB-56
CAS:<p>PSMA-ALB-56: radioactive, PSMA-targeted ligand, antitumor, combines glutamic urea, DOTA, albumin, with iodophenyl or tolyl fragments.</p>Fórmula:C66H95N11O18Forma y color:SolidPeso molecular:1330.52RS 09 TFA
<p>RS 09 TFA is a TLR4 agonist and LPS peptide analogue, promotes NF-κB nuclear translocation, induces inflammatory cytokine secretion in RAW264.7 macrophages.</p>Fórmula:C33H50F3N9O11Pureza:99.78%Forma y color:SolidPeso molecular:805.8MS7829
MS7829 is a first-class DUBTAC targeting cGAS, a critical component in the cGAS-STING pathway.Forma y color:Odour SolidNLRP3-IN-50
NLRP3-IN-50 (compound SN3-1) is a potential inhibitor of NLRP3, offering therapeutic promise for inflammatory diseases.Fórmula:C23H22Cl2N2O4S2Forma y color:SolidPeso molecular:525.47MTvkPABC-P5 TFA
<p>MTvkPABC-P5d TFA, a TLR7 agonist, functions as an immune stimulant. It is applicable in the synthesis of immune-stimulating antibody conjugates (ISAC).</p>Forma y color:Odour Solid4-hydroperoxy 2-Nonenal
CAS:4-HNE, a marker of oxidative stress, arises from oxidized ω-6 fats like linoleic acid and shows cytotoxic and genotoxic effects.Fórmula:C9H16O3Forma y color:SolidPeso molecular:172.224Bectumomab
CAS:<p>Bectumomab (IMMU-LL2) is a humanized IgG2a mAb targeting CD22, used in imaging and staging non-Hodgkin's lymphoma.</p>Forma y color:LiquidTuparstobart
CAS:Tuparstobart (Incagn-02385) is an IgG1κ monoclonal antibody that targets the immune checkpoint receptor protein LAG-3, which is predominantly expressed onForma y color:LiquidGuaiacol-d3
CAS:Guaiacol-d3 is a deuterated form of Guaiacol, which is a phenolic compound known for its ability to inhibit COX-2 expression and NF-κB activation in response to LPS stimulation, exhibiting anti-inflammatory properties.Fórmula:C7H8O2Forma y color:SolidPeso molecular:127.16Bermoprofen
CAS:<p>Bermoprofen (AD-1590) is an anti-inflammatory compound with anti-inflammatory and analgesic activity used in the study of gastric ulcers.</p>Fórmula:C18H16O4Pureza:98.72% - 99.28%Forma y color:SolidPeso molecular:296.32CHBO4
CAS:<p>CHBO4 is an hMAO-B inhibitor that is potent, reversible, competitive and selective.The IC50 value of CHBO4 against hMAO-B in the CHBO assay was 0.031 μM, and</p>Fórmula:C15H10BrFOPureza:98.14%Forma y color:SolidPeso molecular:305.142'2'-cGAMP (sodium salt)
CAS:<p>2'2'-cGAMP, a synthetic CDN, binds STING in the immune response, inducing IFN-β; binds weaker than 2'3'-cGAMP but stronger than other CDNs.</p>Fórmula:C20H24N10O13P2Forma y color:SolidPeso molecular:674.417PSMA-D5
CAS:<p>PSMA-D5 exhibits a binding affinity for PSMA with a Ki of 0.21 nM and becomes useful for PSMA tracing following radiolabeling. When marked with [68Ga], PSMA-D5 contains a DOTA chelator, facilitating the convenient labeling with therapeutic radionuclides such as 177Lu and 225Ac. Additionally, [68Ga]-labeled PSMA-D5 demonstrates exceptional pharmacokinetic properties and significant tumor uptake in 22Rv1 tumors. This compound can be employed in the synthesis and research of radiolabeled conjugates (RDC).</p>Fórmula:C57H80N12O24Forma y color:SolidPeso molecular:1317.31PSMA-DA1
CAS:PSMA–DA1 may be a useful PSMA-targeting radiotheranostic agent.Fórmula:C50H76IN9O20Forma y color:SolidPeso molecular:1250.105Aβ-IN-6
<p>Aβ-IN-6 is an orally active compound exhibiting anti-inflammatory, antioxidant, and anti-oligomeric activities, with significant implications for Alzheimer's</p>Fórmula:C28H31N3O4Forma y color:SolidPeso molecular:473.56GBR-1342
GBR-1342 is a human bispecific antibody targeting CD38 and CD3. It inhibits the activity of cancer cell lines Daudi, RAJI, RPMI8226, IM-9, and NCI-H929, and is applicable to multiple myeloma research.Forma y color:Odour LiquidCD19 CAR mRNA
CD19 CAR mRNA expresses a protein for use in CAR-CD19 T cell therapy, targeting B cell antigen for cancer treatment.Forma y color:SolidTLR8 agonist 2
CAS:<p>TLR8 agonist 2 activates human TLR8 (EC50=3nM), less effective on TLR7 (EC50=33.33μM).</p>Fórmula:C16H22N8Forma y color:SolidPeso molecular:326.408Reslizumab
CAS:Reslizumab (Sch 55700) is a humanized immunoglobulin G (IgG) 4 κ monoclonal antibody, thereby reducing eosinophil production and survival.Pureza:98.1% (SDS-PAGE); 98.6% (SEC-HPLC) - 98.1% (SDS-PAGE); 98.6% (SEC-HPLC)Forma y color:LiquidPeso molecular:N/A3-O-(2'E,4'Z-Decadienoyl)ingenol
3-O-(2'E,4'Z-Decadienoyl)ingenol is a useful organic compound for research related to life sciences and the catalog number is T124104.Fórmula:C30H42O6Forma y color:SolidPeso molecular:498.664-Methylamino antipyrine hydrochloride
CAS:<p>4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole.</p>Fórmula:C12H16ClN3OPureza:98%Forma y color:SolidPeso molecular:253.73Axinelline A
CAS:Axinelline A: COX inhibitor, IC50 of 2.22 μM (COX-2) & 8.89 μM (COX-1), anti-inflammatory.Fórmula:C12H15NO6Forma y color:SolidPeso molecular:269.25
