Inmunología e inflamación
Los inhibidores de inmunología e inflamación son compuestos que modulan la respuesta inmunitaria y los procesos inflamatorios. Estos inhibidores son cruciales para estudiar los mecanismos de regulación inmunitaria, la autoinmunidad y la inflamación crónica, así como para desarrollar tratamientos para enfermedades inflamatorias, alergias y trastornos relacionados con el sistema inmunológico. Al dirigirse a vías clave en el sistema inmunológico, estos inhibidores pueden ayudar a reducir las respuestas inmunitarias excesivas o inadecuadas. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad para apoyar su investigación en inmunología, inflamación y desarrollo terapéutico.
Subcategorías de "Inmunología e inflamación"
- CCR(140 productos)
- CXCR(153 productos)
- Pared celular(5 productos)
- Receptor de IL(108 productos)
- IκB / IKK(59 productos)
- LTR(3 productos)
- MALT(24 productos)
- MRP(6 productos)
- NADPH-oxidasa(1 productos)
- NF-κB(445 productos)
- NOD(17 productos)
- NOS(62 productos)
- Nrf2(82 productos)
- PGE sintasa(31 productos)
- ROS(70 productos)
- TGF-beta / Smad(59 productos)
- TLR(74 productos)
- Tiorredoxina(12 productos)
- gp120 / CD4(4 productos)
Mostrar 11 subcategorías más
Se han encontrado 3269 productos de "Inmunología e inflamación"
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Arginase inhibitor 7
CAS:<p>Arginase Inhibitor 7 (compound A17), an inhibitor of arginase (ARG1), exhibits an IC 50 value of 0.16 μM and possesses high oral bioavailability [1].</p>Fórmula:C14H29BN6O5Forma y color:SolidPeso molecular:372.23Zomiradomide
CAS:Zomiradomide is a PROTAC degradation agent targeting IRAK4,oral, Ikaros (IKZF1) and Aiolos (IKZF3), NF-κB type I interferon, B-cell lymphoma.Fórmula:C45H48F3N7O6SPureza:98.41%Forma y color:SolidPeso molecular:871.97Melredableukin alfa
CAS:Melredableukin alfa, a human IgG1-κ fused with IL2 mutein, is studied for autoimmune hepatitis and ulcerative colitis.Forma y color:LiquidIFN-α Receptor Recognition Peptide 1
CAS:<p>IFN-α Receptor Recognition Peptide 1, associated with receptor interactions, is a peptide of IFN-α.</p>Fórmula:C35H59N13O12SPureza:98%Forma y color:SolidPeso molecular:885.99Perfluorododecanoic acid
CAS:Perfluorododecanoic acid (PFDoA) is a PFAS pollutant causing ROS increase, mitochondrial damage, and neuronal cytotoxicity.Fórmula:C12HF23O2Pureza:98.42%Forma y color:SolidPeso molecular:614.1Pelgifatamab
CAS:<p>Pelgifatamab (BAY-2315497) is a prostate-specific membrane antigen (PSMA) antibody with potential anticancer activity that can be used to study prostate cancer.</p>Pureza:97.9% (SDS-PAGE); 95.1% (SEC-HPLC) - 97.9% (SDS-PAGE); 95.1% (SEC-HPLC)Forma y color:LiquidWAY-605471
CAS:WAY-605471 is a AHR antagonist with IC50 of 0.5 - 1 μM.Fórmula:C14H15NO3S2Pureza:99.62%Forma y color:SolidPeso molecular:309.4Sartorypyrone D
CAS:Sartorypyrone D, from N. fischeri, inhibits NFRD (1.7 μM) and NADH oxidase (3 μM), and fights Gram-positive bacteria.Fórmula:C26H38O4Forma y color:SolidPeso molecular:414.586PMX-53
CAS:PMX-53: MrgX2 agonist; C5aR antagonist; lessens atherosclerotic lesions & metastasis in mice; blocks rat hypernociception.Fórmula:C47H65N11O7Pureza:98%Forma y color:SolidPeso molecular:896.09VEN-02XX
<p>VEN-02XX is an orally active NLRP3 inhibitor capable of penetrating the brain. It effectively suppresses the release of IL-1β and IL-18, with IC50 values of 0.3 and 0.28 μM, respectively. In the 5XFAD/Rubicon KO mouse model, VEN-02XX aids in restoring memory and cognition, inhibits microgliosis, and alleviates neuroinflammation and tau protein pathology. This compound is valuable for Alzheimer's disease (AD) research.</p>Fórmula:C18H16ClF3N4OForma y color:SolidPeso molecular:396.79Hydroxychloroquine Impurity E
CAS:Hydroxychloroquine Impurity E, a byproduct, can block TLR7/9 and inhibit SARS-CoV-2 in vitro.Fórmula:C14H17ClN2OForma y color:SolidPeso molecular:264.75Dalutrafusp alfa
CAS:Dalutrafusp alfa (AGEN-1423; GS-1423) is a bifunctional antibody targeting CD73 and TGF-β, components of the immunosuppressive pathway [1].Forma y color:LiquidRYTVELA TFA
CAS:<p>RYTVELA TFA is a variant interleukin-1 receptor inhibitor with anti-inflammatory activity for the prevention of preterm labor and fetal protection.</p>Fórmula:C38H62N10O12Forma y color:SolidPeso molecular:850.96Mipeginterferon alfa-2b
CAS:<p>Mipeginterferon alfa-2b, an IFNA2b analogue, has 5 modified amino groups out of 11 and weighs 40 kDa.</p>Forma y color:LiquidODN D-SL03
CAS:<p>ODN D-SL03, a C class CpG oligonucleotide, stimulates PBMCs, activating B cells, NK cells & monocytes, and can inhibit tumor growth.</p>Forma y color:SolidPeso molecular:9345Bavunalimab
CAS:Bavunalimab: bispecific anti-CTLA-4/LAG-3 antibody, T-cell activator in NSG mice, for cancer research.Forma y color:LiquidLadanetin-6-O-β-D-glucopyranoside
CAS:<p>Ladanetin-6-O-β-D-glucopyranoside, an active flavonoid, exhibits antioxidative effects and has potential for research into cardioprotective effects [1].</p>Fórmula:C22H22O11Forma y color:SolidPeso molecular:462.4Anti-Human MSLN Antibody (Clone HN1)
<p>Anti-Human MSLN Antibody (Clone HN1) is a humanised monoclonal antibody targeting MSLN (Mesothelin), , blocks the interaction between MSLN and CA125, cancer .</p>Pureza:95%Forma y color:Odour LiquidCAY10512
CAS:CAY10512, a resveratrol analog, is 100x more potent, inhibiting NF-κB with an IC50 of 0.15 μM versus resveratrol's 20 μM.Fórmula:C15H13FOForma y color:SolidPeso molecular:228.2667-O-Methylaloeasinol
CAS:7-O-Methylaloeasinol is a useful organic compound for research related to life sciences. The catalog number is T126468 and the CAS number is 105317-69-9.Fórmula:C20H26O9Forma y color:SolidPeso molecular:410.419iNOs-IN-6
<p>iNOs-IN-6 is an anti-inflammatory agent known for inhibiting the expression of NF-κB, iNOS, and MAPK with an IC50 ranging from 0.2 to 0.62 μM. Additionally, it decreases the levels of pro-inflammatory mediators, such as IL-6, TNF-α, and IL-1β, with an IC50 ranging from 0.4 to 0.69 μM.</p>Forma y color:Odour SolidPepinh-MYD
CAS:<p>Pepinh-MYD, a MyD88 inhibitor, incorporates both a domain sequence from MyD88 TIR and a protein transduction sequence to facilitate cell membrane penetration. This compound disrupts MyD88-mediated TLR signaling pathways, effectively inhibiting associated immune responses. Its design is particularly useful for investigating MyD88's function in viral infections.</p>Fórmula:C151H248N50O35S2Forma y color:SolidPeso molecular:3388.03TPNA10168
CAS:<p>Compound Fr13590, with CAS No. 957942-34-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr13590 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C9H9ClO2S2Forma y color:SolidPeso molecular:248.75Dithianon
CAS:Dithianon: broad-spectrum anthraquinone fungicide; sticks to leaves/fruits; controls various fungi in some produce.Fórmula:C14H4N2O2S2Pureza:98%Forma y color:SolidPeso molecular:296.32Vadastuximab
<p>Vadastuximab (Anti-Human CD33 Recombinant Antibody) is a humanized anti-CD33 monoclonal antibody for the study of acute myeloid leukemia (AML).</p>Pureza:98.5% (SDS-PAGE); 97.3% (SEC-HPLC) - 98.5% (SDS-PAGE); 97.3% (SEC-HPLC)Forma y color:LiquidPeso molecular:145.5 kDaSomantadine
CAS:<p>Somantadine has antiviral activities and can be used for research on preventing and treating coronavirus-related diseases.</p>Fórmula:C14H25NPureza:99.9%Forma y color:SolidPeso molecular:207.35MUC1, mucin core
CAS:<p>MUC1: Type I transmembrane glycoprotein, overexpressed and abnormally glycosylated in cancer, binds ICAM-1 domain 1.</p>Fórmula:C61H101N19O24Forma y color:SolidPeso molecular:1484.588Humanized anti-tac (HAT) binding peptide
CAS:Humanized anti-tac (HAT) binding peptide is a peptide that specifically binds to the Fc region of HAT. HAT is a humanized monoclonal antibody targeting the low-affinity p55 subunit of the interleukin IL-2 receptor. The peptide can be utilized in the development of affinity chromatography media for the purification of specific monoclonal antibodies.Fórmula:C60H103N17O18Forma y color:SolidPeso molecular:1350.56Trifludimoxazin
CAS:Trifludimoxazin is an inhibitor of protoporphyrinogen oxidase and can be used as a herbicide.Fórmula:C16H11F3N4O4SPureza:99.84%Forma y color:SolidPeso molecular:412.34Galectin-8N-IN-2
<p>Galectin-8N-IN-2 (compound 2) is an effective selective inhibitor of Galectin-8N, with a Ki value of 74 μM.</p>Forma y color:Odour SolidISD Control sodium
ISD (interferon stimulatory DNA) Control sodium is a non-immunostimulatory single-stranded oligonucleotide with a sequence identical to its double-stranded counterpart, ISD.Biotin-labeled ODN 2216 sodium
Biotin-labeled ODN 2216 (sodium) serves as a specific agonist for human TLR9 (toll-like receptor 9), facilitating the assessment of CpG ODN cellular uptake andForma y color:Odour SolidGalectin-8-IN-2
CAS:<p>Galectin-8-IN-2 (Compound 10) acts as an inhibitor of galectin-8N [1].</p>Fórmula:C15H20O7Forma y color:SolidPeso molecular:312.32PMX 205 Trifluoroacetate
<p>PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR ; CD88 ) antagonist.</p>Fórmula:C47H63F3N10O8Forma y color:SolidPeso molecular:953.06Siplizumab
CAS:<p>Siplizumab (MEDI-507), an IgG1 antibody targeting CD2, depletes T cells, may treat psoriasis.</p>Pureza:100% (SEC-HPLC) - > 95%Forma y color:LiquidPeso molecular:147.24 kDaAnticancer agent 15
CAS:Anticancer agent 15 raises ROS, causing necroptosis in melanoma cells.Fórmula:C35H40Cl2N2O5Forma y color:SolidPeso molecular:639.61SARS-CoV-2-IN-39
CAS:SARS-CoV-2-IN-39 is a SARS-CoV-2 inhibitor with an EC50 of 1 μM.Fórmula:C14H8ClF4NO3Pureza:99.86%Forma y color:SoildPeso molecular:349.66Olendalizumab
CAS:Olendalizumab (ALXN1007) is a humanized antibody targeting C5a for research on COVID-19-related inflammation.Forma y color:LiquidPerfluorohexane
CAS:Perfluorohexane (AF-0150) is a perfluorocarbon (PFC)-based microbubble formulation for ultrasound contrast and is developmentally toxic.Fórmula:C6F14Pureza:98%Forma y color:Colourless LiquidPeso molecular:338.04Eupenicisirenin C
CAS:Eupenicisirenin C (compound 1), a sirenin derivative, exhibits strong NF-κB inhibitory activities and suppresses the cGAS-STING pathway. Additionally, Eupenicisirenin C inhibits RANKL-induced osteoclast differentiation in bone marrow macrophage cells [1].Fórmula:C13H18O4Peso molecular:238.28PSMα3
CAS:<p>PSMα3 is a peptide compound that can be utilized to induce tolerance in dendritic cells (DCs) for DC vaccination strategies.</p>Fórmula:C128H192N28O30SForma y color:SolidPeso molecular:2635.17C6 L-threo Ceramide (d18:1/6:0)
CAS:C6 L-threo Ceramide: bioactive sphingolipid, cytotoxic to U937 cells (IC50=18μM), non-metabolic, boosts IL-4 in T cells at 10μM.Fórmula:C24H47NO3Forma y color:SolidPeso molecular:397.63NF-κB-IN-9
NF-κB-IN-9, a nuclear factor kappa B (NF-κB) targeting sonosensitizer with excitation and emission wavelengths (λex/λem) of 489/628 nm, features dualFórmula:C62H50N4O4SForma y color:SolidPeso molecular:947.15Ginger extract
CAS:<p>Ginger extract demonstrates (exhibits) anti-cancer, anti-inflammatory, and chemotherapeutic properties in living organisms (in vivo).</p>Forma y color:SolidRomilkimab
CAS:Romilkimab (SAR156597) is a chimeric humanized immunoglobulin (Ig) antibody designed to specifically target interleukins 4 and 13 (IL-4 and IL-13) [1].Forma y color:LiquidN188 TFA
<p>N188 TFA is a radiolabeled ligand based on a bicyclic peptide scaffold, targeting the protein nectin-4, which is overexpressed in various tumors. It can be efficiently labeled with the radioactive isotope 68Ga to form 68Ga-N188, suitable for positron emission tomography (PET) imaging. The development of N188 TFA and its radiolabeled form, 68Ga-N188, holds potential for the diagnosis and treatment of cancers such as urothelial carcinoma.</p>Forma y color:Odour SolidIFN-γ Antagonist 1
CAS:<p>IFN-γ Antagonist 1 (AYCRDGKIGPPKLDIRKEEKQI), an interferon γ (IFN γ) antagonist, effectively inhibits IFN-γ induced HLR/DR antigen expression in Colon 205 cells</p>Fórmula:C115H194N34O34SForma y color:SolidPeso molecular:2629.04Temtokibart
CAS:<p>Temtokibart is a humanized monoclonal antibody targeting IL22RA1, used in autoimmune and inflammatory disease research.</p>Forma y color:LiquidPeso molecular:145.5SN50
CAS:<p>SN50 is a cell-permeable inhibitor of NF-κB nuclear translocation that protects against ventilator-induced acute lung injury in rats.</p>Fórmula:C129H230N36O29SPureza:99.91%Forma y color:SolidPeso molecular:2781.5
