Inmunología e inflamación
Los inhibidores de inmunología e inflamación son compuestos que modulan la respuesta inmunitaria y los procesos inflamatorios. Estos inhibidores son cruciales para estudiar los mecanismos de regulación inmunitaria, la autoinmunidad y la inflamación crónica, así como para desarrollar tratamientos para enfermedades inflamatorias, alergias y trastornos relacionados con el sistema inmunológico. Al dirigirse a vías clave en el sistema inmunológico, estos inhibidores pueden ayudar a reducir las respuestas inmunitarias excesivas o inadecuadas. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad para apoyar su investigación en inmunología, inflamación y desarrollo terapéutico.
Subcategorías de "Inmunología e inflamación"
- CCR(136 productos)
- CXCR(149 productos)
- Pared celular(5 productos)
- Receptor de IL(112 productos)
- IκB / IKK(59 productos)
- LTR(3 productos)
- MALT(23 productos)
- MRP(6 productos)
- NADPH-oxidasa(1 productos)
- NF-κB(443 productos)
- NOD(18 productos)
- NOS(63 productos)
- Nrf2(78 productos)
- PGE sintasa(31 productos)
- ROS(69 productos)
- TGF-beta / Smad(58 productos)
- TLR(66 productos)
- Tiorredoxina(12 productos)
- gp120 / CD4(4 productos)
Mostrar 11 subcategorías más
Se han encontrado 3054 productos de "Inmunología e inflamación"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Clazakizumab
CAS:<p>Clazakizumab: monoclonal antibody targeting IL-6, may inhibit COVID-19 cytokine response, researched for PsA and renal rejection.</p>Forma y color:LiquidTri(TLR4-IN-C34-C2-amide-C3-amide-PEG1)-amide-C3-COOH
<p>Tri(TLR4-IN-C34) linker reduces inflammation by inhibiting TLR4 in cells, shown effective in mouse endotoxemia and enterocolitis.</p>Fórmula:C84H134N10O39Forma y color:SolidPeso molecular:1908.01RDR03785
CAS:<p>The MIF Antagonist IV, RDR 03785 controls the biological activity of MIF. This small molecule/inhibitor is primarily used for Cell Structure applications.</p>Fórmula:C19H18F3NO4Pureza:98.92%Forma y color:SolidPeso molecular:381.35Antibiofilm agent-8
<p>Antibiofilm agent-8 (compound Ru2) boosts antibacterial activity under visible light (400-700 nm, 10 J cm-2). It induces oxidative stress by promoting NADH oxidation and reactive oxygen species (ROS) generation, which disrupts the bacterial cell wall.</p>Fórmula:C35H23ClF6N7PRuPeso molecular:823.03887ARC186
<p>ARC186 is a highly potent aptamer that serves as a complement inhibitor by blocking the convertase-catalyzed activation of C5.</p>Forma y color:SolidPeso molecular:120702.76FAPI-46
CAS:<p>FAPI-46 is a radiotracer for fibroblast activation protein (FAP),conjugated with 68Ga or 177Lu tracer for FAP tumours in positron emission tomography (PET).</p>Fórmula:C41H57F2N11O9Forma y color:SolidPeso molecular:885.96ROS-ERS inducer 2
<p>ROS-ERS inducer 2 (Complex 3f) promotes the generation of intracellular ROS, affects mitochondrial function, facilitates the release of damage-associated molecular patterns (DAMPs), induces immunogenic cell death (ICD), and activates endoplasmic reticulum stress (ERS). It plays a significant role in anti-hepatocellular carcinoma research.</p>Fórmula:C24H23BrClF2N3PtForma y color:SolidPeso molecular:701.9QX006N
<p>QX006N is a humanized monoclonal antibody inhibitor targeting the human interferon α/β receptor 1 (IFNAR1). It is promising for research in systemic lupus erythematosus (SLE) and other IFNAR1-related autoimmune diseases.</p>Forma y color:Odour LiquidEX-A5758
CAS:<p>EX-A5758: novel nNOS-NOS1AP inhibitor, reduces pain & enhances paclitaxel's anti-tumor effect.</p>Fórmula:C10H17NO5Pureza:99.67%Forma y color:SolidPeso molecular:231.25ZSA-51
<p>ZSA-51 is an effective, orally active STING agonist with anticancer properties. It has the capability to remodel the immune microenvironment within tumors and lymph nodes.</p>Fórmula:C16H15NO6SForma y color:SolidPeso molecular:349.358Multiflorin B
CAS:<p>Multiflorin B (compound 5), a kaempferol glycoside, can be extracted from the root of Neocheiropteris palmatopedata.</p>Fórmula:C27H30O15Pureza:98%Forma y color:SolidPeso molecular:594.52Goflikicept
CAS:<p>Goflikicept (RPH 104) binds/inactivates IL-1ß/α; may research STEMI.</p>Forma y color:LiquidIRAK4-IN-26
<p>IRAK4-IN-26 (Compound 21), an IRAK4 inhibitor with an IC50 of 6.2 nM, exhibits an oral bioavailability of 21%.</p>Fórmula:C22H23N5O3Pureza:98%Forma y color:SolidPeso molecular:405.45GB1908
<p>GB1908 is a selective oral inhibitor of galectin-1 (galectin-1), with Ki values of 57 nM for human galectin-1 and 72 nM for mouse galectin-1. It demonstrates over 50-fold selectivity for galectin-1 compared to galectin-3. GB1908 can be utilized in lung cancer research.</p>Fórmula:C18H18Cl2N4O5S2Peso molecular:504.009573-(3-Methoxyphenyl)acrylic acid
CAS:<p>3-(3-Methoxyphenyl)acrylic acid can inhibit free radical generation, has antioxidant potential, and can be used in biochemical experiments and drug synthesis.</p>Fórmula:C10H10O3Pureza:99.91%Forma y color:SolidPeso molecular:178.19STING agonist-29
CAS:<p>CF511: non-nucleotide, small-molecule STING activator; fights SARS-CoV variants.</p>Fórmula:C38H44N14O6Forma y color:SolidPeso molecular:792.85NLRP3-IN-23
<p>NLRP3-IN-23 (Compound 15C) is an inhibitor that significantly impedes heme-mediated activation of the NLRP3 inflammasome at a concentration of 0.1 μM [1].</p>Pureza:98%Forma y color:Odour SolidcGAMP diammonium
<p>cGAMP is a second messenger that triggers interferon production via STING activation upon detecting cytosolic DNA.</p>Fórmula:C20H30N12O13P2Forma y color:SolidPeso molecular:708.47NLRP3-IN-15
CAS:<p>NLRP3-IN-15: potent, selective NLRP3 inflammasome inhibitor; IC50 0.114 μM for IL-1β; for inflammation research.</p>Fórmula:C22H19NO4Forma y color:SolidPeso molecular:361.39PMX 205
CAS:<p>PMX 205 is an effective complement antagonist of the C5a receptor.</p>Fórmula:C45H62N10O6Pureza:98%Forma y color:SolidPeso molecular:839.041-Hydroxy-ibuprofen
CAS:<p>1-Hydroxy Ibuprofen, a metabolite in P. australis, targets COX-1/COX-2 with IC50s: 13 μM/370 μM.</p>Fórmula:C13H18O3Forma y color:SolidPeso molecular:222.28027-epi Maresin 1
CAS:<p>7-epi Maresin 1 is the inactive 7(S) epimer of Maresin 1 , which contains a 7(R) hydroxyl group. It can be used as an experimental negative control.</p>Fórmula:C22H32O4Forma y color:SolidPeso molecular:360.494Reltecimod
CAS:Reltecimod, a CD28 antigen inhibitor, is used potentially for the treatment of necrotizing soft tissue infection.Fórmula:C46H72N10O15SPureza:98%Forma y color:SolidPeso molecular:1037.19dsVACV-70mer sodium
<p>dsVACV-70mer sodium is a 70 base pair double-stranded oligonucleotide that contains a viral DNA motif derived from vaccinia virus DNA. It effectively induces IFN-β through a STING-dependent mechanism.</p>TLR4-IN-C34-C2-amide-C6-OH
<p>TLR4-IN-C34-C2-amide-C6-OH: a linker with TLR4-IN-C34 that curbs TLR4 and inflammation in mice.</p>Fórmula:C25H42N2O11Forma y color:SolidPeso molecular:546.61EB-TCIP
<p>EB-TCIP (BAK-04-212) is a bivalent molecule composed of AP1867 and BI-3812. It facilitates the reversible formation of a ternary complex between FKBPF36V and BCL6BTB, thereby recruiting FKBP12F36V-tagged EWS/FLI1 to DNA sites bound by the transcriptional regulator BCL6, rapidly inducing expression of BCL6 target genes such as SOCS2 and CXCL11. EWS/FLI1 is a fusion transcription factor found in Ewing sarcoma. EB-TCIP is applicable for studying transcriptional dysregulation in cancer.</p>Forma y color:Odour SolidCTT2274
<p>CTT2274 is a prodrug of MMAE. It consists of a prostate-specific membrane antigen (PSMA) binding scaffold, a biphenyl motif, a pH-sensitive phosphoramidate linker, and an MMAE payload. CTT2274 selectively targets and binds to PSMA to deliver MMAE and has the capability to inhibit prostate cancer.</p>Fórmula:C119H159N17O33P2Forma y color:SolidPeso molecular:2417.58NLRP3-IN-76
<p>NLRP3-IN-76 is an orally active NLRP3 inhibitor that suppresses the production of NO and reduces the mRNA levels of pro-inflammatory cytokines (iNOS, IL-6, IL-1β, and TNFα). It exerts anti-inflammatory effects by inhibiting the activation of the NLRP3 inflammasome and the NF-κB signaling pathway. Furthermore, NLRP3-IN-76 can ameliorate DSS-induced colitis and is applicable for studying inflammatory bowel disease (IBD).</p>Forma y color:Odour SolidVensobafusp alfa
CAS:<p>Vensobafusp alfa (KP-104) is a fusion protein composed of an IgG4 monoclonal antibody targeting complement protein C5, combined with the domains 1-5 of complement factor H (FH1-5). It exhibits anti-inflammatory and immunomodulatory properties. The isotype control for Vensobafusp alfa can be referred to as human IgG4(S228P) kappa.</p>Forma y color:LiquidG3-C12
CAS:<p>G3-C12 shows anticancer activity. is a galectin-3 binding peptide, with Kd of 88 nM.</p>Fórmula:C74H115N23O23S2Pureza:98%Forma y color:SolidPeso molecular:1758.99Tuparstobart
CAS:<p>Tuparstobart (Incagn-02385) is an IgG1κ monoclonal antibody that targets the immune checkpoint receptor protein LAG-3, which is predominantly expressed on</p>Forma y color:LiquidZ-VRPR-FMK TFA
<p>Z-VRPR-FMK (TFA), a tetrapeptide, irreversibly inhibits MALT1, protecting against influenza A.</p>Fórmula:C33H50F4N10O8Forma y color:SolidPeso molecular:790.81TMX-201
CAS:<p>TMX-201: TLR7 ligand-phospholipid with potent immune-boosting effect; for breast cancer & melanoma study.</p>Fórmula:C57H93N6O12PForma y color:SolidPeso molecular:1085.36Cafestol palmitate
CAS:<p>Cafestol palmitate is an active compound found in green coffee beans. It can enhance the activity of glutathione S-transferase (GST) in mice and also exhibits weak COX-2 inhibitory activity.</p>Fórmula:C36H58O4Forma y color:SolidPeso molecular:554.843NLRP3-IN-14
CAS:<p>NLRP3-IN-14, potent selective NLRP3 inhibitor, KD 5.87μM; IC50 0.131μM for IL-1β; for inflammation research.</p>Fórmula:C27H28N2O4Forma y color:SolidPeso molecular:444.52Ibuprofen impurity 1
CAS:<p>Ibuprofen impurity 1: anti-inflammatory, inhibits COX-1/COX-2 with IC50s of 13 μM/370 μM.</p>Fórmula:C12H16O2Forma y color:SolidPeso molecular:192.258MLT-231
<p>MLT-231: potent MALT1 Inhibitor, IC50=9 nM; blocks BCL10 cleavage, IC50=160 nM; exhibits antitumor efficacy in mouse ABC-DLBCL model.</p>Forma y color:SolidMethyl 3,4-Dihydroxyphenylacetate
CAS:<p>Methyl 3,4-Dihydroxyphenylacetate is an effective enterovirus 71 (EV71) inhibitor, suppressing EV71 replication in rhabdomyosarcoma (RD) cells, antiviral.</p>Fórmula:C9H10O4Pureza:97.03%Forma y color:SolidPeso molecular:182.17β-Aminoarteether
CAS:<p>β-Aminoarteether (SM934 free base), an orally active derivative of Artemisinin, serves a pivotal role in the research of inflammation and autoimmune disorders,</p>Fórmula:C17H29NO5Pureza:96.09% - 97.02%Forma y color:SolidPeso molecular:327.427-O-Methylaloeasinol
CAS:<p>7-O-Methylaloeasinol is a useful organic compound for research related to life sciences. The catalog number is T126468 and the CAS number is 105317-69-9.</p>Fórmula:C20H26O9Forma y color:SolidPeso molecular:410.419C3a (70-77)
CAS:<p>C3a (70-77) is an octapeptide corresponding to the COOH terminus of C3a.</p>Fórmula:C35H61N13O10Pureza:98%Forma y color:SolidPeso molecular:823.94Sericin
<p>Sericin is a globular protein isolated from silkworm cocoons. It has cognitive enhancement and pain-relieving properties. Additionally, Sericin serves as a cryoprotectant, potentially replacing fetal bovine serum or dimethyl sulfoxide (DMSO). It helps reduce oxidative stress and reactive oxygen species (ROS). Sericin aids in wound repair by promoting collagen production and exhibits activities such as antioxidant, antidiabetic, antihyperlipidemic, anti-inflammatory, moisturizing, wound healing promotion, antibacterial, and antitumor effects.</p>Forma y color:Odour Solid3′-Hydroxy-4′-O-methylglabridin
CAS:<p>3′-Hydroxy-4′-O-methylglabridin effectively prevents NADH-dependent peroxidation, exhibiting potent antioxidant properties [1].</p>Fórmula:C21H22O5Forma y color:SolidPeso molecular:354.4EC1169
CAS:<p>EC1169 is a targeted PSMA ligand that acts to inhibit the proliferation of cells expressing PSMA.</p>Fórmula:C78H112N14O28S3Forma y color:SolidPeso molecular:1790.00Iromycin A
CAS:<p>Iromycin A: a bacterial metabolite inhibiting NOS III over NOS I, blocks NADH oxidation, IC50 = 0.461 µM.</p>Fórmula:C19H29NO2Forma y color:SolidPeso molecular:303.44Zomiradomide
CAS:<p>Zomiradomide is a PROTAC degradation agent targeting IRAK4,oral, Ikaros (IKZF1) and Aiolos (IKZF3), NF-κB type I interferon, B-cell lymphoma.</p>Fórmula:C45H48F3N7O6SPureza:98.41%Forma y color:SolidPeso molecular:871.97ROS-ERS inducer 1
<p>Type II ICD agent, ROS-ERS inducer 1, is a Pt(II)-NHC from 4,5-diarylimidazole, boosting ER stress, ROS, and DAMPs in HCC, outperforming Cisplatin.</p>Fórmula:C24H23F2I2N3PtForma y color:SolidPeso molecular:840.35Anti-Mouse MHC Class I (H-2) Antibody (M1/42.3.9.8)
Anti-Mouse MHC Class I (H-2) Antibody (M1/42.3.9.8) is a rat-derived IgG2a, κ antibody inhibitor specifically targeting mouse MHC Class I.AJ2-30
CAS:AJ2-30: Inhibits SLCl5A4, TLR9-B cell activation, MDP transport, NOD signaling; for inflammation study.Fórmula:C23H22N4Pureza:>99.99%Forma y color:SoildPeso molecular:354.45Pepinh-MYD TFA
<p>Pepinh-MYD TFA is a MyD88 inhibitor that features domain sequences from MyD88TIR and a protein transduction sequence, allowing it to penetrate cell membranes. By disrupting MyD88-mediated TLR pathway signaling, it inhibits related immune responses. Pepinh-MYD TFA shows potential for investigating MyD88's role in viral infections.</p>Fórmula:C151H248N50O35S2·xC2HF3O2Forma y color:SolidPeso molecular:3388.03 (free base)
