Inmunología e inflamación
Los inhibidores de inmunología e inflamación son compuestos que modulan la respuesta inmunitaria y los procesos inflamatorios. Estos inhibidores son cruciales para estudiar los mecanismos de regulación inmunitaria, la autoinmunidad y la inflamación crónica, así como para desarrollar tratamientos para enfermedades inflamatorias, alergias y trastornos relacionados con el sistema inmunológico. Al dirigirse a vías clave en el sistema inmunológico, estos inhibidores pueden ayudar a reducir las respuestas inmunitarias excesivas o inadecuadas. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad para apoyar su investigación en inmunología, inflamación y desarrollo terapéutico.
Subcategorías de "Inmunología e inflamación"
- CCR(140 productos)
- CXCR(153 productos)
- Pared celular(5 productos)
- Receptor de IL(108 productos)
- IκB / IKK(59 productos)
- LTR(3 productos)
- MALT(24 productos)
- MRP(6 productos)
- NADPH-oxidasa(1 productos)
- NF-κB(445 productos)
- NOD(17 productos)
- NOS(62 productos)
- Nrf2(82 productos)
- PGE sintasa(31 productos)
- ROS(70 productos)
- TGF-beta / Smad(59 productos)
- TLR(74 productos)
- Tiorredoxina(12 productos)
- gp120 / CD4(4 productos)
Mostrar 11 subcategorías más
Se han encontrado 3269 productos de "Inmunología e inflamación"
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TLR7 agonist 1
CAS:TLR7 agonist 1 is a selective and oral TLR7 agonist (IC50: 90 nM).Fórmula:C21H25N5OPureza:98%Forma y color:SolidPeso molecular:363.46Emlenoflast
CAS:Emlenoflast (MCC7840) is a selective inhibitor of NLRP3 inflammasome.Fórmula:C19H24N4O3SPureza:97.004% - 98.19%Forma y color:SolidPeso molecular:388.48AZD8848
CAS:AZD8848 is a selective antedrug agonist of toll-like receptor 7 (TLR7). It is developed for the research of asthma and allergic rhinitis.Fórmula:C29H43N7O5Forma y color:SolidPeso molecular:569.7NF-κB-IN-8
CAS:NF-κB-IN-8 is a competitive antagonist of LPS for MD-2 binding, and it impedes the expression of inflammatory factors by engaging MD-2.Fórmula:C24H21N3O3Pureza:98%Forma y color:SolidPeso molecular:399.44NLRP3-IN-19
CAS:JT001 (NLRP3-IN-19) is a potent, specific, and orally active NLRP3 inhibitor that impedes the assembly of the NLRP3 inflammasome.Fórmula:C19H22N4O4SPureza:98%Forma y color:SolidPeso molecular:402.47U-74389G
CAS:U-74389G: an antioxidant that inhibits iron-induced lipid perox. Shields heart, liver, and kidney from ischemic reperfusion damage in animals.Fórmula:C41H54N6O6Forma y color:SolidPeso molecular:726.919ALV1
CAS:ALV1 degrades IKZF1-4, CK1α, RPL4; enhances Helios/CRBN dimer & IL-2 secretion.Fórmula:C25H23ClN4O5Forma y color:SolidPeso molecular:494.93Isofezolac
CAS:<p>Isofezolac (LM 22070), a NSAID, inhibits prostaglandin-synthetase, offering powerful anti-inflammatory and antipyretic effects.</p>Fórmula:C23H18N2O2Forma y color:SolidPeso molecular:354.4IMD-catechol
CAS:IMD-catechol: an imidazoquinolinone-based dimer with NF-κB activity; improves CT26 cancer treatment, low toxicity.Fórmula:C31H34N6O3Pureza:98%Forma y color:SolidPeso molecular:538.64S-MTC
CAS:<p>S-MTC is a selective inhibitor of type I nitric oxide synthase.</p>Fórmula:C7H15N3O2SPureza:98%Forma y color:Off-White Powder / White SolidPeso molecular:205.28Sul-121 HCl
CAS:Sul-121 HCl combats COPD by reducing inflammation and AHR via oxidative stress inhibition.Fórmula:C18H27ClN2O3Pureza:98%Forma y color:SolidPeso molecular:354.87CD73-IN-9
CAS:<p>CD73-IN-9, a potent inhibitor of CD73, may treat cancer by blocking adenosine production that aids tumor growth and spread.</p>Fórmula:C14H11F2N5O2Forma y color:SolidPeso molecular:319.27IKK2-IN-4
CAS:<p>IKK2-IN-4(IKK2 Inhibitor VI) is a highly potent IKK-2 inhibitor with an IC50 value of 25 nM. IKK2-IN-4 inhibited the production of TNF-α in PBMC induced by LPS.</p>Fórmula:C12H11N3O2SPureza:>99.99%Forma y color:SolidPeso molecular:261.3JAK2/STAT3-IN-1
CAS:JAK2/STAT3-IN-1 is a GP130 inhibitor with anti-tumor effects and can be used to study inflammation, autoimmunity and cancer.Fórmula:C34H35BrF3N5O2Pureza:97.35%Forma y color:SolidPeso molecular:682.57WN1316
CAS:WN1316 is a unique neuroprotectant against oxidative injury, being a highly promising remedy for the treatment of amyotrophic lateral sclerosis (ALS).Fórmula:C20H26Cl3N5OForma y color:SolidPeso molecular:458.81COX-2/5-LOX-IN-3
CAS:<p>COX-2/5-LOX-IN-3 inhibits COX-2/5-LOX with IC50s: COX-1 45.73μM, COX-2 5.45μM, 5-LOX 4.33μM; promising for inflammation research.</p>Fórmula:C17H16ClN3O2SForma y color:SolidPeso molecular:361.85XT2
CAS:XT2 is a potent, oral NF-κB-inducing kinase (NIK) inhibitor with an IC50 of 9.1 nM, reduces ALT levels, and curbs immune cell liver infiltration.Fórmula:C19H14FN5OSForma y color:SolidPeso molecular:379.41C5aR-IN-2
CAS:<p>C5aR-IN-2, a potent C5aR inhibitor, shows promise for researching inflammatory diseases.</p>Fórmula:C36H40FN5O2Forma y color:SolidPeso molecular:593.73L-NMMA acetate
CAS:L-NMMA acetate inhibits all NOS types (nNOS, eNOS, iNOS); Ki: 0.18, 0.4, 6 µM respectively.Fórmula:C9H20N4O4Pureza:99.72% - 99.8%Forma y color:White To Off-White SolidPeso molecular:248.28MSU38225
CAS:<p>MSU38225, an Nrf-2 inhibitor, elevates reactive oxygen species (ROS) levels and suppresses the proliferation of human lung cancer cells.</p>Fórmula:C21H19N3Forma y color:SolidPeso molecular:313.4OT-551
CAS:OT-551, a NF-κB inhibitor, is used potentially for the treatment of cataracts and age-related macular degeneration.Fórmula:C13H23NO3Pureza:98%Forma y color:SolidPeso molecular:241.33BI-665915
CAS:BI-665915 is a 5-lipoxygenase activating protein inhibitor.Fórmula:C24H26N8O2Forma y color:SolidPeso molecular:458.52Keap1-Nrf2-IN-13
CAS:Keap1-Nrf2-IN-13 is a PPI inhibitor (IC50: 0.15 μM) that binds Keap1 strongly, useful for oxidative stress and inflammation research.Fórmula:C28H32N2O10S2Forma y color:SolidPeso molecular:620.69Anti-inflammatory agent 21
CAS:Compound 9o: orally active, low-toxicity anti-inflammatory; inhibits NO (IC50: 0.76 μM), blocks NF-κB/MAPK, reduces arthritis symptoms.Fórmula:C24H21FO6Forma y color:SolidPeso molecular:424.42CL264
CAS:CL264, a selective agonist of TLR7, can be used in studies about innate immune signals.Fórmula:C19H23N7O4Pureza:98.01%Forma y color:SolidPeso molecular:413.43Fc 11a-2
CAS:Fc 11a-2, an oral benzimidazole, potently inhibits NLRP3 inflammasome and caspase-1 to prevent colitis.Fórmula:C16H16N2Forma y color:SolidPeso molecular:236.31LAG-3 biner 1
CAS:LAG-3biner 1 (compound 3) is a small molecule ligand for the immune checkpoint Lymphocyte Activation Gene 3 (LAG-3), with a dissociation constant (Kd) of 1.23 μM. It is used in research for targeting LAG-3 in cancer diagnostics.Fórmula:C19H18F3N3O3Peso molecular:393.36Miroprofen
CAS:Miprofen is an analgesic and non-steroidal anti-inflammatory, which means it has anti-inflammatory, antipyretic, and anti-platelet aggregation activities.Fórmula:C16H14N2O2Forma y color:SolidPeso molecular:266.3CID-2858522
CAS:CID-2858522 is an effective and specific antigen receptor-mediated NF-κB activation inhibitor (IC50: 70 nM).Fórmula:C28H39N3O3Pureza:96.12%Forma y color:SolidPeso molecular:465.63WIN 54954
CAS:<p>WIN 54954 is an orally available antiviral agent that inhibits Coxsackievirus and may be used in the study of small ribonucleic acid virus infections.</p>Fórmula:C18H20Cl2N2O3Pureza:98.98%Forma y color:SolidPeso molecular:383.27M62812 free base
CAS:<p>M62812 (free base), a Toll-like receptor 4 (TLR4) signal transduction inhibitor, suppresses activation of endothelial cells and leukocytes and prevents lethal</p>Fórmula:C13H11N3OSForma y color:SolidPeso molecular:257.31c-di-AMP
CAS:c-di-AMP (Cyclic diadenylate) is a STING agonist. It binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway.Fórmula:C20H24N10O12P2Pureza:98%Forma y color:SolidPeso molecular:658.41BC12-4
CAS:<p>BC12-4 is a novel potent inhibitor of IL-2 secretion, it has potent immunomodulatory activity.</p>Fórmula:C19H14N2O3Forma y color:SolidPeso molecular:318.33STING modulator-4
CAS:STING modulator-4: competitive, Ki=0.0933 μM (R232H STING), EC50 >10 μM (p-IRF3, THP-1 cells).Fórmula:C17H18N8OForma y color:SolidPeso molecular:350.38L-Kynurenine sulfate
CAS:L-Kynurenine sulfate activates AHR, leading naive T cells to anti-inflammatory Treg phenotype.Fórmula:C10H14N2O7SForma y color:SolidPeso molecular:306.29RI-962
CAS:RI-962 is a potent and selective inhibitor of RIPK1 that protects cells from necrotic apoptosis by inhibiting RIPK1, RIPK3, and MLKL phosphorylation.Fórmula:C28H28N6O2Pureza:99.39%Forma y color:SoildPeso molecular:480.56PNRI-299
CAS:<p>PNRI-299 is a selective inhibitor of AP-1 transcription(IC50 of 20 uM ).</p>Fórmula:C21H15N5O4Pureza:98%Forma y color:SolidPeso molecular:401.37GSK319347A
CAS:GSK319347A is a dual inhibitor of TBK1 and IKKε that inhibits IKK2 and can be used to study bladder and lung adenocarcinomas.Fórmula:C22H19N3O5S2Pureza:98.42%Forma y color:SolidPeso molecular:469.53FK-330 dihydrate
CAS:<p>FK-330 dihydrate (FR-260330 dihydrate), as a NOS inhibitor, prevents tissue damage caused by ischemia and reperfusion. Cost-effective and quality-assured.</p>Fórmula:C29H32ClF3N6O6Pureza:99.52% - 99.98%Forma y color:SolidPeso molecular:653.05COX-2-IN-2
CAS:COX-2-IN-2 selectively inhibits COX2 (IC50: 0.24 μM); COX-2-IN-1 offers anti-inflammatory and pain relief.Fórmula:C17H12FN3O2SPureza:97.62%Forma y color:SolidPeso molecular:341.36OPC-163493
CAS:OPC-163493 is an orally active, liver-targeted mitochondrial uncoupling agent that diminishes Δψ (delta psi) and mitochondrial ROS (reactive oxygen species)Fórmula:C14H8F3N5SPureza:98%Forma y color:SolidPeso molecular:335.31Veledimex (S enantiomer)
CAS:Veledimex S is the oral S enantiomer of a gene therapy promoter activator and CYP3A4/5 inhibitor.Fórmula:C27H38N2O3Pureza:98%Forma y color:SolidPeso molecular:438.6NOS1-IN-1
CAS:<p>NOS1-IN-1: selective, potent nNOS inhibitor (Ki: 120 nM), less effective on eNOS/iNOS, for neurological disorder research.</p>Fórmula:C14H24F9N7O8Pureza:99.7%Forma y color:SolidPeso molecular:589.37S-Isopropylisothiourea hydrobromide
CAS:S-Isopropylisothiourea hydrobromide is an iNOS inhibitor.Fórmula:C4H11BrN2SPureza:98%Forma y color:SolidPeso molecular:199.11NLRP3-IN-25
CAS:<p>NLRP3-IN-25 (compound 32), an orally available NLRP3 inhibitor, exhibits anti-inflammatory properties by attenuating renal injury in a mouse model of doxorubicin-induced glomerulonephritis and inhibiting IL-1β secretion in THP-1 cells, with an IC 50 value of 21 nM [1].</p>Fórmula:C17H19F3N4O5SForma y color:SolidPeso molecular:448.42COX-2/sEH-IN-1
CAS:COX-2/sEH-IN-1, oral dual inhibitor: COX-2 (IC50=1.24 μM), sEH (IC50=0.40 μM); boosts anti-inflammatory action, cuts heart risk.Fórmula:C23H18F3N5O3SForma y color:SolidPeso molecular:501.48Feprazone
CAS:Feprazone (DA-2370) possesses anti-inflammatory and antiadipogenic properties. Feprazone can be used in studies about the treatment of joint and muscular pain.Fórmula:C20H20N2O2Pureza:99.6% - 99.89%Forma y color:SolidPeso molecular:320.39GCPII-IN-1 TFA
CAS:GCPII-IN-1 TFA (compound 2) is an inhibitor scaffold for glutamate carboxypeptidase II (GCPII, PSMA) with a Ki of 44.3±2.4 nM for use in prostate cancer.Fórmula:C14H22F3N3O9Forma y color:SoildPeso molecular:433.34SZM679
SZM679: Oral RIPK1 inhibitor, Kd 8.6 nM, weak RIPK3 affinity (>5000 nM). Reduces inflammation, Tau phosphorylation in AD research.Fórmula:C27H18F5N3O5SPureza:98%Forma y color:SolidPeso molecular:591.51Keap1-Nrf2-IN-14
CAS:<p>Keap1-Nrf2-IN-14, a KEAP1-NRF2 inhibitor (IC50: 75 nM, Kd: 24 nM), boosts NRF2 gene expression, antioxidative and anti-inflammatory response.</p>Fórmula:C30H29NO8SForma y color:SolidPeso molecular:563.62
