Inmunología e inflamación
Los inhibidores de inmunología e inflamación son compuestos que modulan la respuesta inmunitaria y los procesos inflamatorios. Estos inhibidores son cruciales para estudiar los mecanismos de regulación inmunitaria, la autoinmunidad y la inflamación crónica, así como para desarrollar tratamientos para enfermedades inflamatorias, alergias y trastornos relacionados con el sistema inmunológico. Al dirigirse a vías clave en el sistema inmunológico, estos inhibidores pueden ayudar a reducir las respuestas inmunitarias excesivas o inadecuadas. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad para apoyar su investigación en inmunología, inflamación y desarrollo terapéutico.
Subcategorías de "Inmunología e inflamación"
- CCR(140 productos)
- CXCR(153 productos)
- Pared celular(5 productos)
- Receptor de IL(109 productos)
- IκB / IKK(58 productos)
- LTR(2 productos)
- MALT(24 productos)
- MRP(6 productos)
- NADPH-oxidasa(1 productos)
- NF-κB(446 productos)
- NOD(17 productos)
- NOS(62 productos)
- Nrf2(82 productos)
- PGE sintasa(31 productos)
- ROS(70 productos)
- TGF-beta / Smad(59 productos)
- TLR(74 productos)
- Tiorredoxina(12 productos)
- gp120 / CD4(4 productos)
Mostrar 11 subcategorías más
Se han encontrado 3244 productos de "Inmunología e inflamación"
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iNOS-IN-2
CAS:<p>iNOS-IN-2 (Compound 53) is a potent inducible nitric oxide synthase (iNOS) protein down-regulator.</p>Fórmula:C25H31NO7Forma y color:SolidPeso molecular:457.52iNOs-IN-3
CAS:iNOs-IN-3: oral iNOS inhibitor, IC50 = 3.342 μM, anti-inflammatory, for LPS-induced ALI study.Fórmula:C27H24N2O5SForma y color:SolidPeso molecular:488.55COX-2/15-LOX-IN-1
CAS:<p>COX-2/15-LOX-IN-1 is a dual inhibitor for COX-2/15-LOX with anti-inflammatory properties (IC50: COX-1 10.65μM, COX-2 0.075μM, 15-LOX 2.98μM).</p>Fórmula:C21H21N7S3Forma y color:SolidPeso molecular:467.63Ruzotolimod
CAS:<p>Ruzotolimod, an agonist of TLR7, exhibits promising potential for investigating HBV, COVID-19, and SARS-CoV-2 infections （WO2021130195A1）[1].</p>Fórmula:C14H18N4O5SForma y color:SolidPeso molecular:354.38Heterophdoid A
CAS:Heterophdoid A is an anti-inflammatory agent that inhibits NO production in BV-2 cells (IC50: 5.93 μM).Fórmula:C26H42O10Forma y color:SolidPeso molecular:514.61MitoB
CAS:MitoB is a novel exon of mitochondrial hydrogen peroxide.Fórmula:C25H23BBrO2PForma y color:SolidPeso molecular:477.14TNF-α-IN-18
CAS:<p>TNF-α-IN-18 is a small molecule TNF-α inhibitor that blocks NF-κB translocation, alleviates sepsis in models, and protects against rheumatoid arthritis in mice.</p>Fórmula:C16H7ClF2O4Pureza:99.77%Forma y color:SolidPeso molecular:336.67Prostaglandin G/H synthase 1 inhibitor
CAS:<p>Prostaglandin G/H synthase 1 inhibitor (CP 74006) is a selective D5D inhibitor with an IC(50) value of 20 nM.</p>Fórmula:C13H11ClN2OPureza:99.76%Forma y color:SolidPeso molecular:246.69IRAK4-IN-21
CAS:<p>IRAK4-IN-21: Oral IRAK4 inhibitor, IC50: IRAK4 5 nM, TAK1 56 nM; curbs IL-23, aids autoimmune research.</p>Fórmula:C28H28FN7O2Forma y color:SolidPeso molecular:513.57MIND4-17
CAS:<p>MIND4-17 activates NRF2 by binding Keap1 C151, blocking Keap1-Nrf2, stabilizes Nrf2, and promotes its nuclear entry, with strong antioxidant effects.</p>Fórmula:C20H15N5O3SForma y color:SolidPeso molecular:405.43IKKβ-IN-1
CAS:<p>IKKβ-IN-1 is a potent, orally active inhibitor of IkappaB (IKK-β) (IC50: 0.20 μM).</p>Fórmula:C31H30N4O4SForma y color:SolidPeso molecular:554.66DSR-6434
CAS:<p>DSR-6434 is a selective agonist of TLR7 with antitumor effect. DSR-6434 exhibits EC50s of 7.2 nM and 4.6 nM for human and mouse.</p>Fórmula:C19H28N8O2Pureza:99.78%Forma y color:SolidPeso molecular:400.487-NINA
CAS:non-selective NOS inhibitorFórmula:C7H5N3NaO2Pureza:98%Forma y color:SolidPeso molecular:186.12Keap1-Nrf2-IN-11
CAS:<p>Keap1-Nrf2-IN-11 (6k) inhibits Keap1-Nrf2, KD 0.21 nM; reduces ROS, NO, TNF-α; aids anti-inflammatory research.</p>Fórmula:C36H43N7O8S2Forma y color:SolidPeso molecular:765.9Heme Oxygenase-1-IN-1 hydrochloride
CAS:HO-1-IN-1 hydrochloride is a heme oxygenase 1 (HO-1) inhibitor (IC50: 250 nM).Fórmula:C13H16BrClN2Forma y color:SolidPeso molecular:315.6410-Cl-BBQ
CAS:10-Cl-BBQ is a ligand of aryl hydrocarbon receptor (AhR).Fórmula:C18H9ClN2OForma y color:SolidPeso molecular:304.73COX-2/5-LOX-IN-1
CAS:COX-2/5-LOX-IN-1, a benzothiophen-2-yl pyrazole, inhibits COX-2 & 5-LOX with IC50: COX-1 (12.13μM), COX-2 (0.4μM), 5-LOX (4.96μM). Better than Celecoxib.Fórmula:C14H10ClN3O4S2Forma y color:SolidPeso molecular:383.83Insulin levels modulator
CAS:Insulin level regulators can be used to treat diabetes.Fórmula:C21H23N7OSPureza:98%Forma y color:SolidPeso molecular:421.52ADU-S100 ammonium salt
CAS:<p>ADU-S100 ammonium salt is an activator of stimulator of interferon genes (STING).Cost-effective and quality-assured.</p>Fórmula:C20H30N12O10P2S2Pureza:98%Forma y color:SolidPeso molecular:724.6MK-0703
CAS:MK-0703 is a selective cyclooxygenase-2 inhibitor.Fórmula:C17H22O5SPureza:98%Forma y color:SolidPeso molecular:338.42NLRP3-IN-13
CAS:<p>NLRP3-IN-13 is an NLRP3 inhibitor that inhibits NLRP3-associated inflammation.NLRP3-IN-13 can be used in the study of neurological disorders and inflammation.</p>Fórmula:C19H15N3O3SPureza:99.16%Forma y color:SolidPeso molecular:365.41MIF-IN-5
CAS:MIF-IN-5: reversible MIF inhibitor, IC50 4.8 μM, Ki 3.3 μM.Fórmula:C18H14FN5O2Forma y color:SolidPeso molecular:351.33UC-781
CAS:UC-781, a potent NNRTI, inhibits HIV-1 with a C50 of 5 nM and is stable across pH and temperatures.Fórmula:C17H18ClNO2SPureza:92.17%Forma y color:SolidPeso molecular:335.85NOD2 antagonist 1
CAS:NOD2 antagonist 1 (compound 32): Selective, effective (IC50: 5.23μM), blocks MDP-induced IL-8 in THP-1, IL-6/IL-10/TNF-α in PBMCs.Fórmula:C26H26N4O3SForma y color:SolidPeso molecular:474.57MALT1-IN-3
CAS:<p>MALT1-IN-3 is a potent inhibitor of MALT1 protease (IC50: 0.06 μM) with IC50 values of 0.14 and 0.13 μM for human IL6 and IL10, respectively, in OCI-LY3 cells.</p>Fórmula:C21H19F3N8O2Forma y color:SolidPeso molecular:472.42R110
CAS:<p>R110 shows the potential for cancer research that is a potent, competitive MIF2 tautomerase inhibitor (IC 50 = 15 μM) [1].</p>Fórmula:C15H17ClN2OSForma y color:SolidPeso molecular:308.83AP-1/NF-κB activation inhibitor 1
CAS:<p>AP-1/NF-κB activation inhibitor 1 is a potent inhibitor of AP-1 and NF-κB mediated transcriptional activation ( IC 50 =1 μM), does not blocking basal</p>Fórmula:C13H11F3N4O4Pureza:99.52% - 99.91%Forma y color:SolidPeso molecular:344.25Nrf2 activator-4
CAS:Nrf2 activator-4 is an Nrf2 activator for the treatment of fatty liver disease associated with metabolic dysfunction in humans.Fórmula:C23H24ClF3N2O3Pureza:98.53%Forma y color:SolidPeso molecular:468.9NF-κB/PON1-IN-1
CAS:NF-κB/PON1-IN-1 (Compound 16) is an NF-κB/PON1 pathway inhibitor with antioxidant activity (IC50: 45.76 μM) and hepatoprotective activity.Fórmula:C20H16N6O4S2Forma y color:SolidPeso molecular:468.51NF-κB-IN-11
CAS:<p>NF-κB-IN-11 (Compound 3i) is an inhibitor of NF-κB, effectively blocking TNF-α-induced NF-κB pathway activation and the nuclear translocation of NF-κB.</p>Fórmula:C19H18O5Pureza:98%Forma y color:SolidPeso molecular:326.34C5aR-IN-2
CAS:<p>C5aR-IN-2, a potent C5aR inhibitor, shows promise for researching inflammatory diseases.</p>Fórmula:C36H40FN5O2Forma y color:SolidPeso molecular:593.73Naproxen glucuronide
CAS:Naproxen glucuronide: NSAID, propionic class, eases pain, fever, inflammation. Nonselective COX blocker.Fórmula:C20H22O9Forma y color:SolidPeso molecular:406.38CL264
CAS:CL264, a selective agonist of TLR7, can be used in studies about innate immune signals.Fórmula:C19H23N7O4Pureza:98.01%Forma y color:SolidPeso molecular:413.43Nrf2 activator-3
CAS:Nrf2 activator-3 is an Nrf2 activator with potential anti-inflammatory, antioxidant and anti-tumor activity for the study of neurological diseases.Fórmula:C23H18F3N3O2Pureza:98.52% - 99.84%Forma y color:SolidPeso molecular:425.4RWJ 63556
CAS:RWJ 63556 is an orally active inhibitor of COX-2 selective/5-lipoxygenase, shows anti-inflammatory activities.Fórmula:C11H10FNO3S2Pureza:99.92%Forma y color:SolidPeso molecular:287.33Keap1-Nrf2-IN-13
CAS:Keap1-Nrf2-IN-13 is a PPI inhibitor (IC50: 0.15 μM) that binds Keap1 strongly, useful for oxidative stress and inflammation research.Fórmula:C28H32N2O10S2Forma y color:SolidPeso molecular:620.69M62812 free base
CAS:<p>M62812 (free base), a Toll-like receptor 4 (TLR4) signal transduction inhibitor, suppresses activation of endothelial cells and leukocytes and prevents lethal</p>Fórmula:C13H11N3OSForma y color:SolidPeso molecular:257.31IMD-biphenylA
CAS:IMD-biphenylA, a novel imidazoquinolinone-based dimer, functions as an NF-κB immunomodulator and enhances the adjuvant properties of small molecule immuneFórmula:C35H33N5O2Pureza:98%Forma y color:SolidPeso molecular:555.67c-di-AMP
CAS:c-di-AMP (Cyclic diadenylate) is a STING agonist. It binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway.Fórmula:C20H24N10O12P2Pureza:98%Forma y color:SolidPeso molecular:658.41BC12-4
CAS:<p>BC12-4 is a novel potent inhibitor of IL-2 secretion, it has potent immunomodulatory activity.</p>Fórmula:C19H14N2O3Forma y color:SolidPeso molecular:318.33MIF-IN-1
CAS:<p>MIF-IN-1 (compound 14) inhibits MIF, a cytokine linked to diseases, with pIC50 of 6.87.</p>Fórmula:C15H13N3O5Forma y color:SolidPeso molecular:315.28STING modulator-4
CAS:STING modulator-4: competitive, Ki=0.0933 μM (R232H STING), EC50 >10 μM (p-IRF3, THP-1 cells).Fórmula:C17H18N8OForma y color:SolidPeso molecular:350.38XT2
CAS:XT2 is a potent, oral NF-κB-inducing kinase (NIK) inhibitor with an IC50 of 9.1 nM, reduces ALT levels, and curbs immune cell liver infiltration.Fórmula:C19H14FN5OSForma y color:SolidPeso molecular:379.41L-Kynurenine sulfate
CAS:L-Kynurenine sulfate activates AHR, leading naive T cells to anti-inflammatory Treg phenotype.Fórmula:C10H14N2O7SForma y color:SolidPeso molecular:306.29OPC-163493
CAS:OPC-163493 is an orally active, liver-targeted mitochondrial uncoupling agent that diminishes Δψ (delta psi) and mitochondrial ROS (reactive oxygen species)Fórmula:C14H8F3N5SPureza:98%Forma y color:SolidPeso molecular:335.31CID-2858522
CAS:<p>CID-2858522 is an effective and specific antigen receptor-mediated NF-κB activation inhibitor (IC50: 70 nM).</p>Fórmula:C28H39N3O3Pureza:96.12%Forma y color:SolidPeso molecular:465.63COX-2-IN-20
CAS:COX-2-IN-20 (Compound 5d) is a selective and orally active inhibitor of COX-2 (IC 50 = 17.9 nM) with anti-inflammatory activity [1].Fórmula:C11H9ClFN3O2Forma y color:SolidPeso molecular:269.66Stigmane B
<p>Stigmane B activates Nrf2, decreases apoptosis and ROS, boosts antioxidants, and is neuroprotective.</p>Fórmula:C21H30O4Forma y color:SolidPeso molecular:346.46STING Agonist C11
CAS:<p>STING agonist C11 activates STING, induces type I IFN in cells, phosphorylates IRF3, and lowers various viral titers via STING/IFNAR pathway.</p>Fórmula:C19H18N4O3SForma y color:SolidPeso molecular:382.44NF-κB-IN-8
CAS:NF-κB-IN-8 is a competitive antagonist of LPS for MD-2 binding, and it impedes the expression of inflammatory factors by engaging MD-2.Fórmula:C24H21N3O3Pureza:98%Forma y color:SolidPeso molecular:399.44
