Inmunología e inflamación
Los inhibidores de inmunología e inflamación son compuestos que modulan la respuesta inmunitaria y los procesos inflamatorios. Estos inhibidores son cruciales para estudiar los mecanismos de regulación inmunitaria, la autoinmunidad y la inflamación crónica, así como para desarrollar tratamientos para enfermedades inflamatorias, alergias y trastornos relacionados con el sistema inmunológico. Al dirigirse a vías clave en el sistema inmunológico, estos inhibidores pueden ayudar a reducir las respuestas inmunitarias excesivas o inadecuadas. En CymitQuimica, ofrecemos una amplia selección de inhibidores de alta calidad para apoyar su investigación en inmunología, inflamación y desarrollo terapéutico.
Subcategorías de "Inmunología e inflamación"
- CCR(136 productos)
- CXCR(149 productos)
- Pared celular(5 productos)
- Receptor de IL(112 productos)
- IκB / IKK(59 productos)
- LTR(3 productos)
- MALT(23 productos)
- MRP(6 productos)
- NADPH-oxidasa(1 productos)
- NF-κB(443 productos)
- NOD(18 productos)
- NOS(62 productos)
- Nrf2(78 productos)
- PGE sintasa(31 productos)
- ROS(69 productos)
- TGF-beta / Smad(58 productos)
- TLR(66 productos)
- Tiorredoxina(12 productos)
- gp120 / CD4(4 productos)
Mostrar 11 subcategorías más
Se han encontrado 3055 productos de "Inmunología e inflamación"
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BI 7446
CAS:<p>BI 7446 is a potent and selective cyclic dinucleotide (CDN)-based stimulator of interferon genes (STING) agonist capable of activating all five STING variants</p>Fórmula:C20H22FN9O10P2S2Pureza:98%Forma y color:SolidPeso molecular:693.52Lipid peroxidation inhibitor 1
CAS:<p>Lipid peroxidation inhibitor 1 is an inhibitor of lipid peroxidation (IC50: 0.07 μM).</p>Fórmula:C24H32N2OPureza:98%Forma y color:SolidPeso molecular:364.52BW 755C
CAS:BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways.Fórmula:C10H10F3N3Pureza:96.52%Forma y color:SolidPeso molecular:229.2hnNOS-IN-2
CAS:<p>Compound 17, also known as hnNOS-IN-2, is an inhibitor of human neuronal nitric oxide synthase (hnNOS) that exhibits good metabolic stability.</p>Fórmula:C18H23F2N3Pureza:98%Forma y color:SolidPeso molecular:319.39IKK-IN-1
CAS:IKK-IN-1 is an inhibitor of IKK.Fórmula:C22H26ClN3O4Pureza:98%Forma y color:SolidPeso molecular:431.91Keap1-Nrf2-IN-15
CAS:<p>Keap1-Nrf2-IN-15 (Compound 24a) is a potent inhibitor of the Keap1-Nrf2 protein-protein interaction, displaying IC50 values of 77 nM in a fluorescence</p>Fórmula:C39H35N3O12S2Forma y color:SolidPeso molecular:801.84TLR8 agonist 5
CAS:<p>TLR8 Agonist 5, exhibiting potent efficacy as a TLR8 agonist, demonstrates an EC50 of 20 nM in HEK-Blue hTLR8, effectively activating the immune response.</p>Fórmula:C31H40N6O5Forma y color:SolidPeso molecular:576.69Dapsone hydroxylamine
CAS:<p>Dapsone hydroxylamine (DDS-NOH) promotes methemoglobinemia, impedes catalase (CAT) activity, and suppresses the generation of reactive oxygen species, while</p>Fórmula:C12H12N2O3SPureza:98%Forma y color:SolidPeso molecular:264.3TMV-IN-3
CAS:<p>TMV-IN-3 is a chalcone derivative that inhibits TMV with a 120.3 μg/mL EC50, used in research on infection and cancer.</p>Fórmula:C28H26O4Forma y color:SolidPeso molecular:426.5HBF-0259
CAS:HBF-0259 is an inhibitors of hepatitis B virus surface antigen (HBsAg) secretion with an EC50 of 11.3 μM and a CC50 value of >50 μM in HepG2.2.15 cells.Fórmula:C16H12Cl2FN5Pureza:98.07% - 99.42%Forma y color:SolidPeso molecular:364.2STING agonist-11
CAS:<p>STING agonist-11 is a potent activator of the small molecule cyclic urea class of STING (EC50: 18 nM).STING activation is a highly promising immunotherapy.</p>Fórmula:C25H20ClF4N3O2Forma y color:SolidPeso molecular:505.89NLRP3-IN-18
CAS:<p>NLRP3-IN-18, also known as compound 13, is a potent inhibitor of NLRP3, demonstrating an IC50 value of ≤1.0 µM [1].</p>Fórmula:C19H18ClN3OPureza:98%Forma y color:SolidPeso molecular:339.82Friluglanstat
CAS:<p>Friluglanstat is an inhibitor of the enzyme prostaglandin E synthase (mPGES-1) and exhibits anti-inflammatory activity [1].</p>Fórmula:C25H20ClF3N4O3Pureza:98%Forma y color:SolidPeso molecular:516.9TMV-IN-5
CAS:<p>TMV-IN-5 (compound 1a) serves as an antiviral/antifungal agent, specifically targeting and inhibiting the assembly of the tobacco mosaic virus (TMV) by binding</p>Fórmula:C22H23N3SForma y color:SolidPeso molecular:361.5RIP1 kinase inhibitor 4
CAS:<p>RIP1 Kinase Inhibitor 4 (Compound 3) is an effective inhibitor of RIP1K, exhibiting an EC50 of ≤ 1000 nM [1].</p>Fórmula:C23H23N5Pureza:98%Forma y color:SolidPeso molecular:369.46NLRP3-IN-22
CAS:<p>NLRP3-IN-22 (Compound II-4) is an inhibitor of NLRP3, exhibiting a 67% inhibition rate at a concentration of 10 μM [1].</p>Fórmula:C19H12F3NO4SPureza:98%Forma y color:SolidPeso molecular:407.36α-Pyridoin
CAS:<p>α-Pyridoin (α-pyridoin) is an enediol (enediol) compound that acts as a unique antioxidant.</p>Fórmula:C12H12N2O2Forma y color:SolidPeso molecular:216.24OATD-02
CAS:<p>OATD-02 is an orally active, competitive, reversible, noncovalent inhibitor with slow offset kinetics that targets both Arginase1 and 2, exhibiting inhibitory</p>Fórmula:C12H25BN2O4Pureza:98%Forma y color:SolidPeso molecular:272.15Anti-inflammatory agent 46
CAS:<p>Anti-inflammatory agent 46 (compound 7h), exhibiting nitric oxide (NO) inhibitory properties, demonstrates a high affinity for iNOS through low binding energies</p>Fórmula:C24H19FN2O3SPureza:98%Forma y color:SolidPeso molecular:434.48STING-IN-5
CAS:<p>STING-IN-5 suppresses NO synthesis in macrophages, inhibits STING pathway with IC50 of 1.15 μM, and may aid anti-inflammatory and sepsis research.</p>Fórmula:C47H67NO9S2Pureza:98%Forma y color:SolidPeso molecular:854.17TMV-IN-2
CAS:<p>TMV-IN-2, a chalcone, inhibits TMV with an EC50 of 89.9 μg/mL, used in infection and tumor studies.</p>Fórmula:C27H23FO4Forma y color:SolidPeso molecular:430.47CGA-JK3
CAS:<p>CGA-JK3 is an IkappaB kinase inhibitor in innate immune process.</p>Fórmula:C15H19NO3Pureza:98%Forma y color:SolidPeso molecular:261.32JT002
CAS:<p>JT002 is an orally active NLRP3 inflammasome inhibitor that decreases the production of NLRP3-dependent proinflammatory cytokines (such as IL-1β, IL-1α, IL-18)</p>Fórmula:C20H24N4O5SPureza:98%Forma y color:SolidPeso molecular:432.49Nitric oxide production-IN-1
CAS:<p>Nitric oxide production-IN-1 (Compound 1) is an inhibitor of nitric oxide (NO) production extracted from Tupistra chinensis.</p>Fórmula:C33H52O15Pureza:98%Forma y color:SolidPeso molecular:688.76Argininosuccinic acid disodium
CAS:<p>Argininosuccinic acid disodium, involved in the urea cycle's fourth step, is cleaved by argininosuccinate lyase (ASL) into arginine and fumarate.</p>Fórmula:C10H16N4Na2O6Pureza:98%Forma y color:SolidPeso molecular:334.24EG01377
CAS:<p>EG01377 is a NRP1 antagonist with antiangiogenic, antimigratory, and antitumor activity, Kd 1.32 μM, IC50s 609 nM for NRP1-a1/b1, inactive on NRP2.</p>Fórmula:C26H30N6O6S2Pureza:98%Forma y color:SolidPeso molecular:586.68ST 2825
CAS:<p>ST 2825 is a specific MyD88 dimerization inhibitor. ST2825 inhibition of IL-1β-mediated activation of NF-κB transcriptional activity.</p>Fórmula:C27H28Cl2N4O5SPureza:98%Forma y color:SolidPeso molecular:591.51h-NTPDase-IN-3
CAS:h-NTPDase-IN-3 is an h-NTPDase inhibitor that inhibits h-NTPDase1, h-NTPDase2, h-NTPDase3 and h-NTPDase8.Fórmula:C16H10N4SPureza:98.24%Forma y color:SolidPeso molecular:290.34Caspase-3 activator 1
<p>Caspase-3 activator 1 (compound 4b), a Ru(III) metal complex, effectively inhibits gastric tumor growth and metastasis by mediating caspase-3 cleavage.</p>Fórmula:C28H27N6O2RuS2Pureza:98%Forma y color:SolidPeso molecular:644.75TLR9-IN-1
CAS:<p>TLR9-IN-1: selective, potent human TLR9 inhibitor (IC50: 7 nM), useful for researching immune-related diseases.</p>Fórmula:C23H31N7OForma y color:SolidPeso molecular:421.54Ro26-4550
CAS:<p>Ro26-4550 is a competitive reversible inhibitor of interleukin-2 (IL-2) binding to IL-2R α-subunit (IC50 = 3 μM).</p>Fórmula:C26H30N4O3Pureza:98%Forma y color:SolidPeso molecular:446.54STING Agonist D61
CAS:<p>STING agonist D61 is a compound that activates the stimulator of interferon genes (STING), leading to the induction of IFN3-inducible secreted alkaline</p>Fórmula:C29H29F3N8O4Forma y color:SolidPeso molecular:610.60PK68
CAS:<p>PK68 selectively inhibits RIPK1 (IC50=90nM), potentially useful in inflammation and cancer metastasis studies.</p>Fórmula:C22H24N4O3SPureza:98.09% - 99.64%Forma y color:SolidPeso molecular:424.52COX-2-IN-30
CAS:<p>COX-2-IN-30, a benzenesulfonamide derivative, is an orally active, dual inhibitor of cyclooxygenase-2 (COX-2; IC50 = 49 nM) and cyclooxygenase-1 (COX-1; IC50 =</p>Fórmula:C17H16N6O3SPureza:98%Forma y color:SolidPeso molecular:384.41JNJ-67856633
CAS:<p>JNJ-67856633 is an orally active, first-in-class, potent, selective and allosteric inhibitor of MALT1 protease .</p>Fórmula:C20H11F6N5O2Pureza:99.87%Forma y color:SolidPeso molecular:467.32NLRP3-IN-17
CAS:<p>NLRP3-IN-17 is a potent, selective, and orally active inhibitor of the NLRP3 inflammasome, demonstrating an IC50 of 7 nM.</p>Fórmula:C21H22N4O2SPureza:98%Forma y color:SolidPeso molecular:394.49FEN1-IN-5
CAS:<p>FEN1-IN-5 (compound 12A) is a potent Flap endonuclease-1 (FEN1) inhibitor with an IC50 value of 12 nM, playing a role in DNA repair mechanisms [1].</p>Fórmula:C21H17N3O4SPureza:98%Forma y color:SolidPeso molecular:407.44GBT1118
CAS:<p>GBT1118 is an orally active allosteric modulator of haemoglobin oxygen affinity, enhancing tolerance to acute severe hypoxia and suitable for hypoxia research.</p>Fórmula:C19H20N2O4Pureza:99.69%Forma y color:SolidPeso molecular:340.37NT-0796
CAS:<p>NT-0796 is an inflammasome NLRP3 inhibitor that inhibits NLRP3 activation.NT-0796 is a potential NDT-19795 delivery vector.</p>Fórmula:C23H27N3O4Pureza:99.67%Forma y color:SolidPeso molecular:409.48BF738735
CAS:<p>BF738735 is a selective inhibitor of phosphatidylinositol 4-kinase III beta (PI4KIIIβ, IC50 = 5.7 nM) showing higher activity over α(IC50 = 1.7 μM).</p>Fórmula:C21H19FN4O3SPureza:90%Forma y color:SolidPeso molecular:426.46BDW568
CAS:<p>BDW568, a prodrug of BDW-OH, serves as a stimulator of interferon genes (STING) agonist.</p>Fórmula:C12H12N4O2S2Forma y color:SolidPeso molecular:308.38(-)-Bornyl ferulate
CAS:<p>(-)-Bornyl ferulate is a dual inhibitor of 5-lipoxygenase and cyclooxygenase (COX), exhibiting half-maximal inhibitory concentrations (IC50s) of 10.4 μM for 5-</p>Fórmula:C20H26O4Pureza:98%Forma y color:SolidPeso molecular:330.42PDE4-IN-8
CAS:<p>PDE4-IN-8 is a potent PDE4 inhibitor with IC50 0.93 nM for PDE4B2 and minor impact on IL13, IL4, IFNy (IC50: 4.04, 36.33, 2394 nM).</p>Fórmula:C18H22BNO4Forma y color:SolidPeso molecular:327.18FEN1-IN-7
CAS:<p>FEN1-IN-7 (compound 16), a selective Flap endonuclease-1 (FEN1) inhibitor with an IC50 of 18 nM, plays a role in DNA damage repair in mammalian cells.</p>Fórmula:C16H14N2O6SPureza:98%Forma y color:SolidPeso molecular:362.36Oxidized ATP trisodium salt
CAS:<p>Oxidized ATP trisodium salt (oATP) is a broad-spectrum inhibitor of P2 receptors, irreversibly antagonizing P2X7R activation and inhibiting c-reactive protein (</p>Fórmula:C10H11N5Na3O13P3Pureza:98%Forma y color:SolidPeso molecular:571.11TLR7 agonist 14
CAS:<p>Compound 17b, a TLR7 agonist also known as TLR7 agonist 14, exhibits high potency with an EC50 of 18 nM.</p>Fórmula:C29H36N6O3Forma y color:SolidPeso molecular:516.63TLR8 agonist 6
CAS:<p>Compound A, a potent TLR8 agonist, exhibits an EC50 of 0.052 µM and promotes the production of IL-12p40 in human PBMCs with an EC50 of 0.031 µM.</p>Fórmula:C19H29N7O2Forma y color:SolidPeso molecular:387.48Factor B-IN-2
CAS:<p>Factor B-IN-2 is a potent inhibitor (IC50: 1.5 μM) of complement factor B. Factor B-IN-2 can be used to study inflammatory and immune-related diseases.</p>Fórmula:C25H32N2O4Forma y color:SolidPeso molecular:424.53Glu-urea-Glu-NHS ester
CAS:<p>Compound 21, Glu-urea-Glu-NHS ester, an activated N-hydroxysuccinamide (NHS) ester derivative of Glu-urea-Glu, serves as a pharmacophore for conjugation to prostate specific membrane antigen (PSMA) inhibitors [1].</p>Fórmula:C27H43N3O11Forma y color:SolidPeso molecular:585.64TLR7/8 agonist 8
CAS:<p>TLR7/8 agonist 8 (compound 24m) is a potent dual agonist for toll-like receptors 7 and 8 (TLR7/8), exhibiting half-maximal effective concentrations (EC50s) of</p>Fórmula:C24H30N6OForma y color:SolidPeso molecular:418.53
