NF-κB
El factor nuclear kappa-light-chain-enhancer de células B activadas (NF-κB) es un factor de transcripción que regula la expresión de genes involucrados en respuestas inmunitarias, inflamación, supervivencia celular y proliferación. El NF-κB se activa en respuesta a varios estímulos, incluidos citocinas, patógenos y señales de estrés. La desregulación de la señalización de NF-κB está asociada con enfermedades inflamatorias crónicas, cáncer y trastornos autoinmunes. En CymitQuimica, ofrecemos una selección integral de moduladores de la vía NF-κB para apoyar su investigación en inflamación, oncología y regulación inmunitaria.
Se han encontrado 362 productos para "NF-κB".
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SP-100030
CAS:SP-100030: Strong NF-κB/AP-1 inhibitor, IC50=50 nM. Reduces IL-2, IL-8, TNF-alpha, and murine CIA.Fórmula:C14H5ClF9N3OPureza:99.79%Forma y color:SolidPeso molecular:437.65Ref: TM-T24816
500mgA consultar1mg34,00€5mg70,00€1mL*10mM (DMSO)78,00€10mg99,00€25mg230,00€50mg358,00€100mg513,00€NFATc1-IN-1
CAS:NFATc1-IN-1 (A04) inhibits RANKL-induced osteoclast formation with 1.57 μM IC50, blocking NFATc1 translocation.Fórmula:C13H8F2INO2Pureza:99.98%Forma y color:SolidPeso molecular:375.11IKK-IN-1
CAS:IKK-IN-1 is an inhibitor of IKK.Fórmula:C22H26ClN3O4Pureza:98%Forma y color:SolidPeso molecular:431.91Dimethoxycurcumin
CAS:Dimethoxycurcumin is a stable curcumin analog causing epigenetic shifts in leukemia cells, affecting gene expression.Fórmula:C23H24O6Pureza:99.87%Forma y color:SolidPeso molecular:396.43Ref: TM-T19853
5mg52,00€1mL*10mM (DMSO)52,00€10mg77,00€25mg133,00€50mg225,00€100mg330,00€200mg470,00€(Rac)-BAY-985
CAS:(Rac)-BAY-985 is a potent, ATP-competitive and selective inhibitor of TBK1(IC50 of 1.5 nM),with antitumor efficacy.Fórmula:C27H30F3N9OPureza:98%Forma y color:SolidPeso molecular:553.58GGTI 2147
CAS:GGTI 2147 decreased Rac1 activity, down-regulated p65 expression, and ameliorated OGD/R-induced neuronal apoptosis.Fórmula:C28H30N4O3Pureza:98.24%Forma y color:SolidPeso molecular:470.56ACHP Hydrochloride
CAS:ACHP Hydrochloride (IKK-2 Inhibitor VIII) is a highly potent and selective IKK-β inhibitor with an IC50 of 8.5 nM.Fórmula:C21H25ClN4O2Pureza:99.83%Forma y color:SolidPeso molecular:400.9Ref: TM-T10237
1mg63,00€5mg137,00€1mL*10mM (DMSO)150,00€10mg215,00€25mg355,00€50mg512,00€100mg737,00€500mg1.468,00€Ginsenoside Rk1
CAS:Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures.Fórmula:C42H70O12Pureza:98.46% - 99.13%Forma y color:White SolidPeso molecular:767.00CGA-JK3
CAS:CGA-JK3 is an IkappaB kinase inhibitor in innate immune process.Fórmula:C15H19NO3Pureza:98%Forma y color:SolidPeso molecular:261.32IKK-IN-4
CAS:IKK-IN-4 is a potent and selective inhibitor of IkappaB kinase 2 with IC 50 values of 45 and 650 nM against IKKβ and IKKα, respectively [1].Fórmula:C18H19N5SForma y color:SolidPeso molecular:337.44Bay 65-1942 (R form)
CAS:Bay 65-1942 R form is the less active R-form of Bay 65-1942. Bay 65-1942 is a selective and ATP-competitive IKKβ inhibitor.Fórmula:C22H25N3O4Pureza:98%Forma y color:SolidPeso molecular:395.45TBK1-IN-1
CAS:TBK1-IN-1 is a TANK-binding kinase 1 inhibitor with anticancer activity.TBK1-IN-1 inhibits the expression of TBK1 downstream target genes, cxcl10 and ifnβ.Fórmula:C27H37N7O2Pureza:99.81% - >99.99%Forma y color:White SolidPeso molecular:491.63Glabrescone C
CAS:Glabrescone C exhibits strong anti-inflammatory properties through direct binding to IKKα/β.Fórmula:C19H22O7Forma y color:SolidPeso molecular:362.37PHA-408
CAS:PHA-408 is a novel potent, highly selective and ATP-competitive inhibitor of IKB kinase-2.Fórmula:C29H27ClFN7O2Pureza:97.26%Forma y color:SolidPeso molecular:560.02Ref: TM-T24629
1mg93,00€5mg197,00€1mL*10mM (DMSO)243,00€10mg313,00€25mg520,00€50mg740,00€100mg982,00€IR-Crizotinib
CAS:IR-Crizotinib is a conjugate of the near-infrared dye IR-786 and Crizotinib, an NF-κB-inducing kinase (NIK) inhibitor, with an IC50 of 3.381 μM for intracranialFórmula:C53H57Cl2FIN7OPureza:98%Forma y color:SolidPeso molecular:1024.88PF-184
PF-184: potent IKK-2 inhibitor, selective over 30+ kinases; useful for asthma & COPD research. IC50: 37 nM.Fórmula:C32H32ClFN6O4Forma y color:SolidPeso molecular:619.09NF-κB-IN-13
CAS:NF-κB-IN-13 (compound 12) markedly suppresses LPS-induced NF-κB activation and NO synthesis in RAW264.7 macrophages, exhibiting anti-inflammatory properties [1Fórmula:C20H20O5Pureza:98%Forma y color:SolidPeso molecular:340.37IMD-biphenylC
CAS:IMD-biphenylC: New, dual-action imidazoquinolinone dimer; inhibits tumor growth, low inflammation/toxicity.Fórmula:C35H33N5O3Pureza:98%Forma y color:SolidPeso molecular:571.67IMD-vanillin
CAS:IMD-vanillin is a novel compound characterized as an imidazoquinolinone-derived dimer with NF-κB immunomodulatory properties.Fórmula:C37H45N7O4Pureza:98%Forma y color:SolidPeso molecular:651.8
