NF-κB
El factor nuclear kappa-light-chain-enhancer de células B activadas (NF-κB) es un factor de transcripción que regula la expresión de genes involucrados en respuestas inmunitarias, inflamación, supervivencia celular y proliferación. El NF-κB se activa en respuesta a varios estímulos, incluidos citocinas, patógenos y señales de estrés. La desregulación de la señalización de NF-κB está asociada con enfermedades inflamatorias crónicas, cáncer y trastornos autoinmunes. En CymitQuimica, ofrecemos una selección integral de moduladores de la vía NF-κB para apoyar su investigación en inflamación, oncología y regulación inmunitaria.
Se han encontrado 384 productos de "NF-κB"
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Gypenoside L
CAS:Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release.Fórmula:C42H72O14Pureza:99.42% - 99.65%Forma y color:SolidPeso molecular:801.01Ginsenoside Rg1
CAS:Ginsenoside Rg1 (Panaxoside Rg1) is a class of steroid glycosides, and triterpene saponins found exclusively in the plant genus Panax (ginseng).Fórmula:C42H72O14Pureza:99% - 99.92%Forma y color:White Crystalline PowderPeso molecular:801.01Ref: TM-T5S0754
5mg46,00€1mL*10mM (DMSO)49,00€10mg58,00€25mg92,00€50mg137,00€100mg200,00€200mg295,00€Rhoifolin
CAS:Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.Fórmula:C27H30O14Pureza:98.11% - 98.58%Forma y color:SolidPeso molecular:578.52Ginsenoside Rg2
CAS:Ginsenoside Rg2 (Chikusetsusaponin I) is one of the major active components of ginseng, act as an NF-κB inhibitor.Fórmula:C42H72O13Pureza:99.77% - 99.78%Forma y color:SolidPeso molecular:785.01Ref: TM-T2873
2mg37,00€5mg52,00€1mL*10mM (DMSO)87,00€10mg88,00€25mg131,00€50mg188,00€100mg279,00€500mg658,00€Myrislignan
CAS:Myrislignan exhibits anti-inflammatory, anti-cancer properties, hinders NF-κB pathway, curbs A549 cell growth, and triggers apoptosis and cell cycle arrest.Fórmula:C21H26O6Pureza:98.77% - 99.41%Forma y color:SolidPeso molecular:374.43Ref: TM-T4S1540
1mg44,00€5mg87,00€1mL*10mM (DMSO)102,00€10mg137,00€25mg236,00€50mg385,00€100mg560,00€Ginsenoside Rg6
CAS:Ginsenoside Rg6 inhibits the proliferation and induces apoptosis of human lymphoma JK cellsFórmula:C42H70O12Pureza:97.34%Forma y color:SolidPeso molecular:767Stachydrine
CAS:Stachydrine, found in leonurus herb, aids blood flow, blocks NF-κB pathway, and indicates citrus intake.Fórmula:C7H13NO2Pureza:99.94% - ≥95%Forma y color:SolidPeso molecular:143.18(Rac)-Benpyrine
CAS:(Rac)-Benpyrine is a potent and orally active inhibitor of TNF-α.Fórmula:C16H16N6OPureza:98.44%Forma y color:SolidPeso molecular:308.34Ref: TM-T8692
1mg46,00€2mg62,00€5mg92,00€1mL*10mM (DMSO)105,00€10mg152,00€25mg295,00€50mg442,00€100mg620,00€200mg875,00€Cornuside
CAS:Cornuside boosts immunity, reduces inflammation, protects heart and liver, and guards against brain injury by modulating stress responses.Fórmula:C24H30O14Pureza:99.86% - >99.99%Forma y color:SolidPeso molecular:542.491-Caffeoylquinic acid
CAS:1-Caffeoylquinic acid: a lignin precursor with anti-influenza, antioxidant properties, and moderates post-meal glucose release.Fórmula:C16H18O9Pureza:99.15% - 99.16%Forma y color:SolidPeso molecular:354.31BMS-345541
CAS:BMS-345541 (IKK Inhibitor III) is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM, respectively.Fórmula:C14H17N5Pureza:99.36% - 99.74%Forma y color:SolidPeso molecular:255.32Micheliolide
CAS:Micheliolide(MCL) is a sesquiterpene lactone which inhibits various inflammatory response.Fórmula:C15H20O3Pureza:98% - 99.37%Forma y color:SolidPeso molecular:248.32Ref: TM-T5688
1mg44,00€5mg113,00€1mL*10mM (DMSO)124,00€10mg177,00€25mg299,00€50mg447,00€100mg623,00€500mg1.305,00€IMM-H007
CAS:IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expressionFórmula:C22H23N5O8Pureza:97.73%Forma y color:SolidPeso molecular:485.45Ref: TM-T9010
1mg38,00€5mg92,00€1mL*10mM (DMSO)124,00€10mg128,00€25mg215,00€50mg304,00€100mg411,00€200mg570,00€QNZ
CAS:QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.Fórmula:C22H20N4OPureza:99.17% - 99.18%Forma y color:White SolidPeso molecular:356.42Ref: TM-T6204
1mg40,00€2mg54,00€1mL*10mM (DMSO)87,00€5mg88,00€10mg133,00€25mg178,00€50mg313,00€100mg465,00€200mg673,00€Bay 11-7085
CAS:Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).Fórmula:C13H15NO2SPureza:99.76% - 99.94%Forma y color:White SolidPeso molecular:249.33Ref: TM-T1934
2mg34,00€5mg48,00€1mL*10mM (DMSO)58,00€10mg63,00€25mg80,00€50mg117,00€100mg187,00€200mg243,00€Licochalcone D
CAS:Licochalcone D may treat melanoma and heart injury, halt cell spread, and reduce inflammation and allergies.Fórmula:C21H22O5Pureza:99.03% - 99.9%Forma y color:SolidPeso molecular:354.4TOMATIDINE HYDROCHLORIDE
CAS:Tomatidine hydrochloride (Tomatidine HCl) is a steriodal alkaloid structurally similar to Cyclopamine but does not inhibit hedgehog pathway.Fórmula:C27H46ClNO2Pureza:99.75% - ≥95%Forma y color:SolidPeso molecular:452.11Demethyleneberberine
CAS:Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria eitherFórmula:C19H18NO4Pureza:98.08% - 99.18%Forma y color:SolidPeso molecular:324.35Morusin
CAS:Morusin shows anti-tumor, antioxidant, and anti-inflammatory properties by inhibiting STAT3, NFκB, and inducing apoptosis.Fórmula:C25H24O6Pureza:98.68% - 99.8%Forma y color:SolidPeso molecular:420.45
