NF-κB
El factor nuclear kappa-light-chain-enhancer de células B activadas (NF-κB) es un factor de transcripción que regula la expresión de genes involucrados en respuestas inmunitarias, inflamación, supervivencia celular y proliferación. El NF-κB se activa en respuesta a varios estímulos, incluidos citocinas, patógenos y señales de estrés. La desregulación de la señalización de NF-κB está asociada con enfermedades inflamatorias crónicas, cáncer y trastornos autoinmunes. En CymitQuimica, ofrecemos una selección integral de moduladores de la vía NF-κB para apoyar su investigación en inflamación, oncología y regulación inmunitaria.
Se han encontrado 384 productos de "NF-κB"
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Nitidine chloride
CAS:1.Fórmula:C21H18ClNO4Pureza:96.59% - 99.55%Forma y color:SolidPeso molecular:383.823'-Sialyllactose
CAS:3'-Sialyllactose (3'-SL), a prebiotic, supports immunity, reduces inflammation and arthritis, and is low-toxicity for research.Fórmula:C23H39NO19Forma y color:SolidPeso molecular:633.55CAFESTOL
CAS:Cafestol, an ERK inhibitor, suppresses PGE2 and COX-2 by blocking NF-kB in LPS-stimulated RAW264.7 cells.Fórmula:C20H28O3Pureza:97.06% - 99.08%Forma y color:SolidPeso molecular:316.43BEC hydrochloride
CAS:BEC hydrochloride (BEC HCl) is a competitive arginase inhibitor, which bind slowly. Ki of BEC HCl is 0.31 μM (pH7.5) for Arginase II.Fórmula:C5H12BNO4S·ClHPureza:98.65% - 99.28%Forma y color:SolidPeso molecular:229.49Ref: TM-T6779
1mg37,00€5mg84,00€1mL*10mM (DMSO)84,00€10mg144,00€25mg268,00€50mg439,00€100mg628,00€200mg870,00€Flavanomarein
CAS:Flavanomarein: Antioxidant with radical scavenging, lipid peroxidation inhibition, and lipid-lowering in HepG2 cells.Fórmula:C21H22O11Pureza:98.63% - 99.54%Forma y color:SolidPeso molecular:450.39Theaflavin 3,3′-digallate
CAS:Theaflavin 3,3'-digallate, a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancerFórmula:C43H32O20Pureza:98.71% - 99.86%Forma y color:SolidPeso molecular:868.70Ref: TM-T5429
1mg87,00€5mg169,00€10mg268,00€1mL*10mM (DMSO)268,00€25mg462,00€50mg647,00€100mg873,00€200mg1.153,00€Denosumab
CAS:Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK ligandFórmula:C6404H9912N1724O2004S50Pureza:95.9% (SDS-PAGE); 98.4% (SEC-HPLC) - 99.90%Forma y color:LiquidPeso molecular:144.71 kDaNeochlorogenic acid
CAS:Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.Fórmula:C16H18O9Pureza:99.12% - 99.54%Forma y color:White PowderPeso molecular:354.31Ref: TM-T6S1538
1mg34,00€5mg71,00€1mL*10mM (DMSO)77,00€10mg90,00€25mg147,00€50mg208,00€100mg309,00€200mg447,00€OPHIOPOGONIN D
CAS:Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.Fórmula:C44H70O16Pureza:99.46% - ≥95%Forma y color:SolidPeso molecular:855.02Licochalcone D
CAS:Licochalcone D may treat melanoma and heart injury, halt cell spread, and reduce inflammation and allergies.Fórmula:C21H22O5Pureza:99.03% - 99.9%Forma y color:SolidPeso molecular:354.4Vanillic Acid
CAS:Vanillic Acid (Acide vanillique) is used as a condiment in food, which used in wine. It is an intermediate in the production of vanillin from ferulic acid.Fórmula:C8H8O4Pureza:99.82%Forma y color:White Odourless Crystals Or PowderPeso molecular:168.15Iron sucrose
CAS:Iron sucrose (Sucroferric oxyhydroxide) is treatment of iron deficiency anemia.Fórmula:C18H24Fe2O24Pureza:99.97%Forma y color:SolidPeso molecular:736.1Ginsenoside Rk3
CAS:Ginsenosides Rk3 & Rh4 may treat inflammation and ischemic heart disease.Fórmula:C36H60O8Pureza:99.88%Forma y color:SolidPeso molecular:620.86Ref: TM-T6S1495
1mg80,00€5mg169,00€10mg241,00€1mL*10mM (DMSO)268,00€25mg404,00€50mg597,00€100mg850,00€Flaconitine
CAS:Flaconitine (Acetylaconitine) is an NF-κB inhibitor and an alkaloid.Fórmula:C36H49NO12Pureza:98% - 99.84%Forma y color:SolidPeso molecular:687.77(E/Z)-IT-603
CAS:(E/Z)-IT-603 is a cell-permeable c-Rel inhibitor. IT-603 directly and reversibly binds to c-Rel to change its conformation and blocks its DNA binding activity.Fórmula:C11H9BrN2O3SPureza:99.35%Forma y color:SolidPeso molecular:329.17Ref: TM-T8799
1mg56,00€5mg119,00€1mL*10mM (DMSO)133,00€10mg192,00€25mg356,00€50mg565,00€100mg802,00€200mg1.099,00€2-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC
CAS:2-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC is Inhibitior of IKKβ.Fórmula:C11H10N2OSPureza:99.48%Forma y color:SolidPeso molecular:218.27Sulfuretin
CAS:Sulfuretin protects HepG2 cells from oxidative damage by scavenging ROS and activating HO-1 via Nrf2/ARE and JNK/ERK pathways.
Fórmula:C15H10O5Pureza:98.91% - 99.86%Forma y color:SolidPeso molecular:270.24MLN120B
CAS:MLN120B is a selective and ATP competitive IKKβ inhibitor (IC50: 60 nM).Fórmula:C19H15ClN4O2Pureza:98.92%Forma y color:SolidPeso molecular:366.8Ref: TM-TQ0306
1mg50,00€2mg66,00€5mg90,00€1mL*10mM (DMSO)110,00€10mg152,00€25mg313,00€50mg537,00€100mg735,00€BOT-64
CAS:BOT-64 is an IKK-2 inhibitor which targets the Ser177 and/or Ser181 residues in the kinase's activation loop domain.BOT-64 is a cell-permeable benzoxathioleFórmula:C15H15NO2SPureza:99.73%Forma y color:SolidPeso molecular:273.35Ref: TM-T8705
1mg50,00€1mL*10mM (DMSO)102,00€5mg110,00€10mg170,00€25mg323,00€50mg494,00€100mg665,00€200mg893,00€18α-Glycyrrhetinic acid
CAS:18α-Glycyrrhetinic acid (Enoxolone) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid.Fórmula:C30H46O4Pureza:98.54% - 99.68%Forma y color:SolidPeso molecular:470.68
