NF-κB
El factor nuclear kappa-light-chain-enhancer de células B activadas (NF-κB) es un factor de transcripción que regula la expresión de genes involucrados en respuestas inmunitarias, inflamación, supervivencia celular y proliferación. El NF-κB se activa en respuesta a varios estímulos, incluidos citocinas, patógenos y señales de estrés. La desregulación de la señalización de NF-κB está asociada con enfermedades inflamatorias crónicas, cáncer y trastornos autoinmunes. En CymitQuimica, ofrecemos una selección integral de moduladores de la vía NF-κB para apoyar su investigación en inflamación, oncología y regulación inmunitaria.
Se han encontrado 383 productos de "NF-κB"
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PTP1B-IN-1
CAS:PTP1B-IN-1 (PTP1B inhibitor) is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B) (IC50 : 1.6 mM)Fórmula:C8H8N2O3SPureza:99.27%Forma y color:SolidPeso molecular:212.2318α-Glycyrrhetinic acid
CAS:18α-Glycyrrhetinic acid (Enoxolone) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid.Fórmula:C30H46O4Pureza:98.54% - 99.68%Forma y color:SolidPeso molecular:470.68Triacetylresveratrol
CAS:Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity, it inhibits the phosphorylation of STAT3 and NFκB in pancreatic cancer cells.
Fórmula:C20H18O6Pureza:99.81%Forma y color:Off White PowderPeso molecular:354.35Neochlorogenic acid
CAS:Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.Fórmula:C16H18O9Pureza:99.12% - 99.54%Forma y color:White PowderPeso molecular:354.31Ref: TM-T6S1538
1mg34,00€5mg71,00€1mL*10mM (DMSO)77,00€10mg90,00€25mg147,00€50mg208,00€100mg309,00€200mg447,00€Galloylpaeoniflorin
CAS:Galloylpaeoniflorin (6'-O-Galloyl paeoniflorin) may be developed as a cytoprotector against ROS-mediated oxidative stress.Fórmula:C30H32O15Pureza:99.82%Forma y color:SolidPeso molecular:632.57Chelidonic acid
CAS:Chelidonic acid, in Chelidonium majus, acts as an analgesic, antimicrobial, CNS sedative, and has anti-inflammatory properties.Fórmula:C7H4O6Pureza:99.03%Forma y color:SolidPeso molecular:184.10Iron sucrose
CAS:Iron sucrose (Sucroferric oxyhydroxide) is treatment of iron deficiency anemia.Fórmula:C18H24Fe2O24Pureza:99.97%Forma y color:SolidPeso molecular:736.1yangonin
CAS:Yangonin (Y100550) is a novel CB1 receptor ligand with affinity for human recombinant CB1 receptors.Fórmula:C15H14O4Pureza:98.82% - 99.55%Forma y color:Pale Yellow PowderPeso molecular:258.27Ref: TM-T3S0738
1mg66,00€5mg128,00€1mL*10mM (DMSO)167,00€10mg195,00€25mg330,00€50mg489,00€100mg695,00€BOT-64
CAS:BOT-64 is an IKK-2 inhibitor which targets the Ser177 and/or Ser181 residues in the kinase's activation loop domain.BOT-64 is a cell-permeable benzoxathioleFórmula:C15H15NO2SPureza:99.73%Forma y color:SolidPeso molecular:273.35Ref: TM-T8705
1mg50,00€1mL*10mM (DMSO)102,00€5mg110,00€10mg170,00€25mg323,00€50mg494,00€100mg665,00€200mg893,00€Dendrophenol
CAS:Dendrophenol (Moscatilin) is a natural product isolated from the stem of Dendrobium loddigesii Rolfe, act as a NF-κB inhibitor. Antineoplastic activity.Fórmula:C17H20O5Pureza:98.2% - 99.36%Forma y color:SolidPeso molecular:304.34Ref: TM-T3S1707
1mg99,00€2mg138,00€5mg215,00€1mL*10mM (DMSO)234,00€10mg319,00€25mg530,00€50mg755,00€100mg1.018,00€Dauricine
CAS:1.Fórmula:C38H44N2O6Pureza:99.24% - 99.75%Forma y color:White PowderPeso molecular:624.77Berbamine
CAS:Berbamine is a natural product extracted from Phellodendron amurense.Fórmula:C37H40N2O6Pureza:98.92% - 99.67%Forma y color:White Crystal PowderPeso molecular:608.72Pyrrolidinedithiocarbamate ammonium
CAS:Pyrrolidinedithiocarbamate ammonium (1-Pyrrolidinedithiocarboxylic acid ammonium salt), a selective NF-κB inhibitor, inhibits translation of nitric oxideFórmula:C5H12N2S2Pureza:98% - >99.99%Forma y color:Off-White To Pale Yellow CrystalsPeso molecular:164.29Asperulosidic acid
CAS:Asperulosidic acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities. ASPA is related to the inhibition of inflammatory cytokines.Fórmula:C18H24O12Pureza:99.47%Forma y color:SolidPeso molecular:432.38Ref: TM-TN1410
1mg120,00€2mg170,00€5mg260,00€1mL*10mM (DMSO)286,00€10mg432,00€25mg708,00€50mg964,00€100mg1.288,00€Astaxanthin
CAS:Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.Fórmula:C40H52O4Pureza:95.10% - 99.79%Forma y color:Needles From Acetone/Light Petroleum SolidPeso molecular:596.84Nitidine chloride
CAS:1.Fórmula:C21H18ClNO4Pureza:96.59% - 99.55%Forma y color:SolidPeso molecular:383.82Rocaglamide
CAS:Rocaglamide (Roc-A) from Aglaia treats coughs, injuries, asthma, skin issues, and inhibits NF-κB in T-cells.Fórmula:C29H31NO7Pureza:95.32% - 99.67%Forma y color:SolidPeso molecular:505.56Ref: TM-TQ0131
500µg155,00€1mg187,00€5mg410,00€1mL*10mM (DMSO)449,00€10mg710,00€25mg1.381,00€50mg2.352,00€7,4'-Dihydroxyflavone
CAS:7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti.Fórmula:C15H10O4Pureza:99.39% - 99.6%Forma y color:SolidPeso molecular:254.24GSK8612
CAS:GSK8612 is a highly selective and potent inhibitor of Tank-binding Kinase-1 (TBK1, pIC50: 6.8) .Fórmula:C17H17BrF3N7O2SPureza:99.68% - 99.99%Forma y color:SolidPeso molecular:520.33Cyclo(his-pro)
CAS:Cyclo(his-pro) is a cyclic dipeptide that shields against oxidative damage by activating Nrf2.Fórmula:C11H14N4O2Pureza:99.87%Forma y color:SolidPeso molecular:234.25
