CCR
Los receptores de quimiocinas C-C (CCRs) son un grupo de GPCR que responden a las quimiocinas, moléculas de señalización que guían la migración de células inmunitarias hacia sitios de inflamación o infección. Los CCR desempeñan un papel crucial en las respuestas inmunitarias, la inflamación y el desarrollo de diversas enfermedades, incluidas las enfermedades autoinmunes y el cáncer. La modulación de la actividad de los CCR se está explorando como una estrategia terapéutica para afecciones como la artritis reumatoide, la esclerosis múltiple y la infección por VIH. En CymitQuimica, ofrecemos una gama de moduladores de CCR de alta calidad para apoyar su investigación en inmunología, inflamación y desarrollo terapéutico.
Se han encontrado 154 productos para "CCR".
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CB-0821
CAS:CB-0821 is a high-affinity CCR5 inhibitor with a Ki of 0.04 nM. It effectively binds to the hydrophobic pocket of the CCR5 protein, hindering the interaction between viral proteins and CCR5, thereby blocking virus entry. CB-0821 holds potential for anti-HIV research.Fórmula:C35H24N8Forma y color:SolidPeso molecular:556.62CH-0076989
CAS:CH-0076989 is a chemokine receptor CCR3 agonist.Fórmula:C24H22Br2N2O2Forma y color:SolidPeso molecular:530.25INCB-9471 dihydrochloride
CAS:INCB-9471 HCl: a potent CCR5 antagonist, blocks monocyte migration & HIV-1.Fórmula:C30H42Cl2F3N5O2Pureza:98%Forma y color:SolidPeso molecular:632.59BAY-3153
CAS:BAY-3153 is a selective CCR1 ( C-C motif chemokine receptor 1 ) antagonist (human IC 50 =3 nM ; rat IC 50 =11 nM ; mice IC 50 =81 nM) .Fórmula:C25H29Cl2N3O4Pureza:98%Forma y color:White SolidPeso molecular:506.42BMS-741672
CAS:BMS-741672 is a potent, selective CCR2 antagonist for the treatment of neuropathic pain.Fórmula:C25H33F3N6O2Forma y color:SolidPeso molecular:506.56TAK-661
CAS:TAK-661 is an inhibitor of eosinophil chemotaxis (eosinophil chemotaxis) that significantly alleviates late-phase bronchoconstriction while inhibiting the proliferation of eosinophils in bronchoalveolar lavage (BAL) and their infiltration into the airway walls.Fórmula:C13H21N5O3SForma y color:SolidPeso molecular:327.40PF-07054894
CAS:PF-07054894: potent CCR6 antagonist, targets GPCR, for inflammatory bowel disease research.Fórmula:C24H30N6O4Forma y color:SolidPeso molecular:466.53Ophiobolin C
CAS:inhibitor of human CCR5 binding to HIV-1 gp120Fórmula:C25H38O3Pureza:98%Forma y color:SolidPeso molecular:386.57CCR1 antagonist 11 hydrochloride
Oral CCR1 antagonist A1B1 targets h/m/rCCR1 (IC50: 0.03/0.58/0.32 μM), potential for treating inflammatory diseases.Forma y color:SolidCCR7 Ligand 1
CAS:CCR7-Cmp2105 is a thiadiazole-dioxide allosteric antagonist for CCR7 with a Kd of 3 nM and IC50 of 7.3 μM against arrestin binding.Fórmula:C22H29N5O5SForma y color:SolidPeso molecular:475.56CCR1 antagonist 13
CAS:CCR1 antagonist13 is a selective small molecule antagonist of CCR1.Fórmula:C25H27ClFN3O4Forma y color:SolidPeso molecular:487.95CXCR2/CCR7 antagonist-1
CAS:CXCR2/CCR7 antagonist-1 (compound 6) is a potent dual antagonist of CXCR2 and CCR7, with IC50 values of 0.0046 μM and 0.0014 μM, respectively. It is valuable for research in tumor metastasis and autoimmune diseases.Fórmula:C23H27N3O5Forma y color:SolidPeso molecular:425.48CCR5 antagonist 1
CAS:CCR5 antagonist 1 is a CCR5 antagonist extracted from WO 2004054974 A2. It can inhibit HIV replication.Fórmula:C39H46ClF2N5O3SPureza:98%Forma y color:SolidPeso molecular:738.33AZD-5672
CAS:AZD-5672 is an antagonist of CCR5 with an IC50 of 0.32 nM.Fórmula:C32H38F2N2O5S2Pureza:98.1%Forma y color:SolidPeso molecular:632.78Ref: TM-T30260
1mg119,00€5mg261,00€1mL*10mM (DMSO)318,00€10mg365,00€25mg532,00€50mg745,00€100mg1.009,00€
