ROS

Allopurinol is a Xanthine Oxidase Inhibitor. The mechanism of action of allopurinol is as a …

Camalexin is a phytoalexin isolated from Camelina sativa. It has antifungal, antibacterial, antiproliferative, and anticancer …

Acetylcysteine is the N-acetyl derivative of CYSTEINE. It is used as a mucolytic agent to …

Avermectin B1 (Abamectin) is served as anthelmintic and insecticide.

Beta-Carotene is a naturally-occurring retinol (vitamin A) precursor obtained from certain fruits and vegetables with …

Delphinidin-3-sambubioside chloride has antioxidant activity.

10,12-Tricosadiynoic acid is a highly selective and orally active inhibitor of acyl-CoA oxidase-1 (ACOX1). It …

Mefloquine, a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ …

GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 decreases apoptosis. GSK2795039 is …

Febuxostat is a xanthine oxidase Inhibitor.

Gallic acid is found in almost all plants. Plants known for their high gallic acid …

AA147 is a small molecule endoplasmic reticulum (ER) proteostasis regulator. The selectively activates ATF6 arm …

Topiroxostat is a selective xanthine oxidase inhibitor developed for treatment and management of hyperuricemia and …

Ciprofloxacin hydrochloride is a broad-spectrum antimicrobial carboxyfluoroquinoline.

Vitamin C is a potent reducing and antioxidant agent that functions in fighting bacterial infections, …

(E/Z)-BCI attenuates LPS-induced inflammatory mediators and ROS production in macrophage cells via activating the Nrf2 …

Mefloquine is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.

Tetrahydroxyquinone is a molecule best known as a primitive anticataract drug, is also a highly …

Baicalein is a xanthine oxidase inhibitor.

1, 2-Dihydro-4-methoxy-2-oxo-3-pyridinecarbonitrile was reported as xanthine oxidase inhibitor.

F-1 is IC50s of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALKWT, …

Ciprofloxacin, a synthetic broad spectrum fluoroquinolone antibiotic, inhibits bacterial DNA gyrase. It is more active …

Tiopronin, a sulfhydryl acylated derivative of glycine, leads to a reduction in urinary cystine concentration …

Nortrachelogenin is a novel agent for prostate cancer therapy with ability to inhibit Akt membrane …

Macrocarpal C, isolated from the fresh leaves of Eucalyptus globulus Labill. (Lan An) and identified …

Cudraflavone B has anti-proliferative activity, mouse brain monoamine oxidase (MAO) inhibitory effects, apoptotic actions in …

Cearoin has anti-inflammatory, and antiallergic activities, it can markedly inhibit inflammatory responses including LPS-induced NO …

Daidzin 6''-O-malonate may have anticancer activity.

Cyanidin-3-O-sambubioside chloride is inhibitors of BPDE-induced NF-kB activity. It inhibits the enzyme activity by competing …

Cyclocurcumin, a curcumin derivative, exhibits anticancer, anti-inflammatory, and immune-modulating abilities and is a potential compound …

Physalin A exerts anti-tumor activity in non-small cell lung cancer cell lines by suppressing JAK/STAT3 …

Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.

5-Galloylquinic acid as an index for the baking intensity of oolong teas. It has antioxidant …

Dalbergioidin exhibits tyrosinase inhibitory activity with an IC50 of 20 mM. It shows a melanin …

(+)-1-Hydroxypinoresinol 1-O-beta-D-glucoside exhibits peroxynitrite, total ROS and DPPH radical scavenging activities with IC50 values of …

AlbA-DCA is a conjugate formed by the attachment of Albiziabioside A to a dichloroacetate acid …

Allicin exerts antioxidant, bactericidal, anti-cancer, anti-inflammatory activities, it exerts an inhibitory immunomodulatory effect on intestinal …

Berberine chloride hydrate (Natural Yellow 18 chloride hydrate) is an alkaloid isolated from the Chinese …

Kushenol W is a natural product

Pyrroside B shows stronger antioxidative activity than that of α-tocopherol.

Kushenol C is a good 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenger, and it exhibits inhibitory activity against Sodium-dependent …

Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and …

Trichosanatine and squamosamide, as potential candidates as lead compounds for further study in drug development …

Bisacurone has anti-oxidant, anti-inflammatory, and anti-metastatic activities, it may have a protective effect against ethanol-induced …

Futoquinol is an anti-platelet activating factor principle from the stem part of Piper futokadsura (Piperaceae), …

Cristacarpin exhibits moderate but selective activity towards DNA repair-deficient yeast mutants. It promotes endoplasmic reticulum …

Matairesinol has radical and superoxide scavenging activities,; it also has anti-angiogenic activity by suppressing mROS …

Myricanone has antioxidant, and anticancer activities, it has apoptosis-promoting ability by triggering caspase activation, and …

Licoricidin, is a potent anti-metastatic agent, which can markedly inhibit the metastatic and invasive capacity …

Bacoside A has a possible anticancer activity that could be inducing cell cycle arrest and …

Diosbulbin D shows direct toxic effect on hepatocytes, the mechanism could be associated with oxidative …

Griffipavixanthone inhibits the growth of human Non-small-cell lung cancer H520 cells in dose- and time-dependent …

Picrasidine I has antiosteoclastogenic effect by inhibiting inflammation induced activation of MAPKs, NF-κB and ROS …

Isoangustone A has antitumor activity, it can induce G1 cycle arrest in DU145 human prostate …

Altholactone may be a potential antimicrobial agent, particularly in ciprofloxacin-refractory S. aureus and E. faecalis …

3,5-Di-tert-butylphenol induces accumulation of reactive oxygen species. 3,5-Di-tert-butylphenol exhibits anti-biofilm and antifungal activities.

(-)-Syringaresinol may be a potential chemotherapeutic agent for the treatment of cancer; it against H/R-induced …

Isodunnianol exhibits anti-AChE activity with an IC50 value of 13.0 uM; it also exhibits neurite …

Traumatic Acid is a product of the hydroperoxide lyase pathway in plants. Potential as a …

Martynoside is a natural selective estrogen receptor modulator, which has antioxidative, anti-muscle fatigue, anticancer and …

Sugiol has antioxidant efficacy, it has significant scavenging activities of 1,1-diphenyl-2-picryl hydrazyl, nitric oxide, superoxide …

Dunnianol shows anti-inflammatory activity and moderate antibacterial activity.

1,5,6-Trihydroxy-3-methoxyxanthone exhibits scavenging activity at 10 uM, it can reduce the viability of HL-60 cells …

Alpha-Amyrin is an inhibitor of trypsin and chymotrypsin with antineoplastic effects. alpha-Amyrin can be used …

Hernandezine is an activator of AMPK activator and a selective reversing agent for ABCB1-mediated MDR …

Xanthoxyletin shows potent antibacterial, fungicidal, and algicidal properties, it also has anticancer, and anti-inflammatory activities. …

Brandioside shows strong antioxidant, and neuroprotective effects, it significantly attenuates glutamate-induced neurotoxicity at concentrations ranging …

Malvidin chloride has anti-spermatogenic, and antioxidant activities. It can prevent endothelial dysfunction by inhibiting ROS …

Silybin B and silybin A are potent inhibitors of both raloxifene 4'- and 6-glucuronidation in …

De-O-methyllasiodiplodin exhibits radical scavenging, moderate antibacterial, and potential anti-inflammatory effects, it shows moderate suppression effects …

1,6-O,O-Diacetylbritannilactone(OODBL) has anti-inflammatory activity, it has a potential therapeutic efficacy on inflammatory diseases especially allergic …

Kobophenol A has antimicrobial, and anti-inflammatory activities, it might be a candidate for treatment of …

20-Deoxocarnosol has antioxidant activity of measuring the decay of the radical cation diphenyl-picrylhydrazyl (DPPH).It also …

Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1), which is a …

(+)-Medioresinol possesses antioxidative, a lesishmanicidal activity and cardiovascular disease risk reduction, it has antiamyloidogenic activity …