Receptor de IL
Los receptores de interleucina (receptores IL) son un grupo de receptores que se unen a las interleucinas, una familia de citocinas que desempeñan roles esenciales en la regulación del sistema inmunológico, la inflamación y la hematopoyesis. La desregulación de la señalización de interleucinas está asociada con diversas enfermedades inflamatorias y autoinmunes, lo que convierte a los receptores IL en objetivos críticos para la intervención terapéutica. Se están explorando los antagonistas de los receptores IL para el tratamiento de afecciones como la artritis reumatoide, la psoriasis y las enfermedades inflamatorias intestinales. En CymitQuimica, ofrecemos una gama de moduladores de receptores IL de alta calidad para apoyar su investigación en señalización de citocinas, inmunología y terapia de enfermedades inflamatorias.
Se han encontrado 87 productos de "Receptor de IL"
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Anti-IL-6R Reference Antibody (Vobarilizumab-Fc)
CAS:Vobarilizumab (ALX-0061) is a humanized specific antibody targeting IL-6R and ALB, used in research on autoimmune diseases like rheumatoid arthritis.Pureza:>95%Forma y color:LiquidPeso molecular:78.2 kDaPF-07038124 HCl
CAS:PF-07038124 HCl is a selective and potent PDE4 inhibitor with an IC50 of 0.5 nM for PDE4B2.PF-07038124 HCl inhibits IL-13, IL-4, and IFNγ, and can be used in the study of skin disorders such as atopic dermatitis and plaque psoriasis.Fórmula:C18H23BClNO4Pureza:97.34% - 99.13%Forma y color:SoildPeso molecular:363.64Risankizumab
CAS:Risankizumab (BI 655066) is a monoclonal antibody for psoriasis, targeting IL-23, with high affinity (Kd <10 pM) and an IC50 of 2 pM.Pureza:SDS-PAGE:95.3%;SEC-HPLC:98.3%Forma y color:LiquidPeso molecular:145.85 kDaBermekimab
CAS:Bermekimab (MABp1), an anti-interleukin-1α (IL-1α) monoclonal antibody.Bermekimab has potential anti-inflammatory activity to prevent skin inflammation.Forma y color:LiquidPeso molecular:145.45 kDaIxekizumab
CAS:Ixekizumab: IgG4 antibody, neutralizes IL-17A (<3 pM), treats severe plaque psoriasis & arthritis.Pureza:98.86% (SEC-HPLC) - > 99.3% (SDS-PAGE); 95.4% (SEC-HPLC)Forma y color:LiquidPeso molecular:146.2 kDaYQ128
CAS:YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.Fórmula:C27H29ClN2O4S2Pureza:99.89%Forma y color:SolidPeso molecular:545.11Ref: TM-T13375
1mg52,00€5mg113,00€10mg177,00€25mg289,00€50mg485,00€100mg700,00€1mL*10mM (DMSO)137,00€Nidanilimab
CAS:Nidanilimab (CAN04) is an IL1RAP antibody with 1.10 pM affinity and antitumor effects on NSCLC and PDAC.
Pureza:> 95%Forma y color:SoildPeso molecular:150 kDaOrdesekimab
CAS:Ordesekimab (AMG 714) is a human anti-IL-15 IgG1 κ monoclonal antibody for studying NRCD.Pureza:> 95%Forma y color:LiquidPeso molecular:145.12 kDaSiltuximab
CAS:Siltuximab（CNTO-328） is a monoclonal antibody with anti-tumor activity targeting IL-6 for the study of giant lymph node hyperplasia (MCD) and COVID-19.Pureza:100% (SEC-HPLC) - > 95%Forma y color:LiquidPeso molecular:144.98 kDaSarilumab
CAS:Sarilumab: Potent IL-6 blocker, human antibody, reduces inflammation, treats rheumatoid arthritis.Pureza:97.4%Forma y color:LiquidPeso molecular:144.12 kDaElsilimomab
CAS:Elsilimomab (B-E8) is a monoclonal antibody targeting IL-6, inhibiting the induction of bone marrow stromal cell senescence by dnmt3a mutation clones.Pureza:>95%Forma y color:LiquidPeso molecular:145.96 kDaBriakinumab
CAS:Briakinumab (ABT-874) is a monoclonal antibody targeting IL-12, used in the research of psoriasis multiple sclerosis.Pureza:>95%Forma y color:LiquidPeso molecular:143.86 kDaTildrakizumab
CAS:Tildrakizumab (SCH 900222) is a humanized antibody against IL-23, with a 136 pM Kd, used for psoriasis research.Pureza:> 95%Forma y color:LiquidPeso molecular:144.44 kDaBrodalumab
CAS:Brodalumab (AMG 827), a human IgG2 monoclonal antibody, inhibits IL-17R, treating psoriasis.Pureza:98.3%Forma y color:LiquidPeso molecular:144.06 kDaOlamkicept
CAS:Olamkicept (FE-301) is a soluble gp130-Fc-fusion protein that inhibits interleukin 6 (IL-6) trans signaling.Pureza:98.2% (SDS-PAGE); 98.8% (SEC-HPLC) - 99.3% (SDS-PAGE); 97.6% (SEC-HPLC)Forma y color:LiquidPeso molecular:93.14 kDa2-Benzothiazolamine
CAS:2-ABT: nitrogen-rich heterocycle used in drug synthesis, inhibits P450, with anti-inflammatory, anticonvulsant, anticancer properties.Fórmula:C7H6N2SPureza:99.09% - 99.3%Forma y color:Plates From Water Physical Description Odorless Gray To White Powder (Ntp 1992)Peso molecular:150.2IL-15-IN-1
CAS:IL-15-IN-1 is a selective and potent Interleukin 15 (IL-15) inhibitor, inhibiting the proliferation of IL-15-dependent cells (IC50: 0.8 μM).Fórmula:C30H36N6O4SPureza:99.16%Forma y color:SolidPeso molecular:576.71Ref: TM-T11634
1mg88,00€5mg170,00€10mg259,00€25mg429,00€50mg605,00€100mg815,00€200mg1.093,00€1mL*10mM (DMSO)210,00€Enokizumab
CAS:Enokizumab (MEDI-528) is a monoclonal antibody against interleukin IL-9. Enokizumab can be used to study asthma.
Pureza:SDS-PAGE:95% SEC-HPLC:99.23%Forma y color:LiquidPeso molecular:145.98 kDaSpesolimab
CAS:Spesolimab (BI 655130) is an antibody targeting IL-36 receptor, key in immunity, for systemic pustular psoriasis and dermatitis studies.Pureza:> 95%Forma y color:LiquidPeso molecular:150 kDaVunakizumab
CAS:Vunakizumab is a humanized IgGκ monoclonal antibody targeting IL-17A, often linked to interleukin 22 to form Vunakizumab-IL22.Pureza:95%Forma y color:LiquidPeso molecular:146.38 kDa
