Receptor de IL
Los receptores de interleucina (receptores IL) son un grupo de receptores que se unen a las interleucinas, una familia de citocinas que desempeñan roles esenciales en la regulación del sistema inmunológico, la inflamación y la hematopoyesis. La desregulación de la señalización de interleucinas está asociada con diversas enfermedades inflamatorias y autoinmunes, lo que convierte a los receptores IL en objetivos críticos para la intervención terapéutica. Se están explorando los antagonistas de los receptores IL para el tratamiento de afecciones como la artritis reumatoide, la psoriasis y las enfermedades inflamatorias intestinales. En CymitQuimica, ofrecemos una gama de moduladores de receptores IL de alta calidad para apoyar su investigación en señalización de citocinas, inmunología y terapia de enfermedades inflamatorias.
Se han encontrado 110 productos de "Receptor de IL"
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Sarilumab
CAS:Sarilumab: Potent IL-6 blocker, human antibody, reduces inflammation, treats rheumatoid arthritis.Pureza:97.4%Forma y color:LiquidPeso molecular:144.12 kDaBermekimab
CAS:Bermekimab (MABp1), an anti-interleukin-1α (IL-1α) monoclonal antibody.Bermekimab has potential anti-inflammatory activity to prevent skin inflammation.Forma y color:LiquidPeso molecular:145.45 kDaSiltuximab
CAS:Siltuximab（CNTO-328） is a monoclonal antibody with anti-tumor activity targeting IL-6 for the study of giant lymph node hyperplasia (MCD) and COVID-19.Pureza:100% (SEC-HPLC) - > 95%Forma y color:LiquidPeso molecular:144.98 kDaBRD6989
CAS:BRD6989, a cortistatin A analog, inhibits CDK8/19, enhances IL-10, and binds CDK8 with a 200 nM IC50.Fórmula:C16H16N4Pureza:99.43%Forma y color:SolidPeso molecular:264.33Ref: TM-T14778
1mg35,00€5mg70,00€10mg97,00€25mg187,00€50mg283,00€100mg419,00€200mg607,00€1mL*10mM (DMSO)78,00€Nidanilimab
CAS:<p>Nidanilimab (CAN04) is an IL1RAP antibody with 1.10 pM affinity and antitumor effects on NSCLC and PDAC.</p>Pureza:> 95%Forma y color:SoildPeso molecular:150 kDaAbrezekimab
CAS:Abrezekimab (VR 942), a humanized antibody, blocks IL-13/IL-13Rα1, for asthma/lung disease study.Pureza:98.34% (SEC-HPLC) - 98.34% (SEC-HPLC)Forma y color:LiquidPeso molecular:48.1 kDaBrodalumab
CAS:Brodalumab (AMG 827), a human IgG2 monoclonal antibody, inhibits IL-17R, treating psoriasis.Pureza:98.3%Forma y color:LiquidPeso molecular:144.06 kDaRisankizumab
CAS:Risankizumab (BI 655066) is a monoclonal antibody for psoriasis, targeting IL-23, with high affinity (Kd <10 pM) and an IC50 of 2 pM.Pureza:SDS-PAGE:95.3%;SEC-HPLC:98.3%Forma y color:LiquidPeso molecular:145.85 kDaTildrakizumab
CAS:Tildrakizumab (SCH 900222) is a humanized antibody against IL-23, with a 136 pM Kd, used for psoriasis research.Pureza:> 95%Forma y color:LiquidPeso molecular:144.44 kDaIL-15-IN-1
CAS:IL-15-IN-1 is a selective and potent Interleukin 15 (IL-15) inhibitor, inhibiting the proliferation of IL-15-dependent cells (IC50: 0.8 μM).Fórmula:C30H36N6O4SPureza:99.16%Forma y color:SolidPeso molecular:576.71Ref: TM-T11634
1mg88,00€5mg170,00€10mg259,00€25mg429,00€50mg605,00€100mg815,00€200mg1.093,00€1mL*10mM (DMSO)210,00€Dupilumab
CAS:Dupilumab (REGN-668) is a systemic immunomodulator for AD.Pureza:95.00% - >99.2%Forma y color:LiquidPeso molecular:149.8 kDa2-Benzothiazolamine
CAS:2-ABT: nitrogen-rich heterocycle used in drug synthesis, inhibits P450, with anti-inflammatory, anticonvulsant, anticancer properties.Fórmula:C7H6N2SPureza:99.09% - 99.3%Forma y color:Plates From Water Physical Description Odorless Gray To White Powder (Ntp 1992)Peso molecular:150.2Spesolimab
CAS:Spesolimab (BI 655130) is an antibody targeting IL-36 receptor, key in immunity, for systemic pustular psoriasis and dermatitis studies.Pureza:> 95%Forma y color:LiquidPeso molecular:150 kDaOlokizumab
CAS:Revdofilimab (ABBV-368) is a human IgG monoclonal antibody targeting OX 40 with potential anticancer activity.Pureza:99% (SDS-PAGE); 98.3% (SEC-HPLC) - 99% (SDS-PAGE); 98.3% (SEC-HPLC)Forma y color:LiquidImsidolimab
CAS:Imsidolimab (ANB 019) is a humanized anti-IL-36R monoclonal antibody that inhibits IL-36 signaling and can be used to study systemic pustular psoriasis.Pureza:99.1% (SDS-PAGE); 96.7% (SEC-HPLC) - 99.1% (SDS-PAGE); 96.7% (SEC-HPLC)Forma y color:LiquidLevilimab
CAS:Levilimab (BCD-089) is a fully humanized human monoclonal antibody targeting membrane-bound and soluble IL-6 R for the study of rheumatoid arthritis.Pureza:97.8% (SDS-PAGE); 97.3% (SEC-HPLC) - 97.8% (SDS-PAGE); 97.3% (SEC-HPLC)Forma y color:LiquidEnokizumab
CAS:<p>Enokizumab (MEDI-528) is a monoclonal antibody against interleukin IL-9. Enokizumab can be used to study asthma.</p>Pureza:SDS-PAGE:95% SEC-HPLC:99.23%Forma y color:LiquidPeso molecular:145.98 kDaOlamkicept
CAS:Olamkicept (FE-301) is a soluble gp130-Fc-fusion protein that inhibits interleukin 6 (IL-6) trans signaling.Pureza:98.2% (SDS-PAGE); 98.8% (SEC-HPLC) - 99.3% (SDS-PAGE); 97.6% (SEC-HPLC)Forma y color:LiquidPeso molecular:93.14 kDaOrdesekimab
CAS:Ordesekimab (AMG 714) is a human anti-IL-15 IgG1 κ monoclonal antibody for studying NRCD.Pureza:> 95%Forma y color:LiquidPeso molecular:145.12 kDaAnti-IL-6R Reference Antibody (Vobarilizumab-Fc)
CAS:Vobarilizumab (ALX-0061) is a humanized specific antibody targeting IL-6R and ALB, used in research on autoimmune diseases like rheumatoid arthritis.Pureza:>95%Forma y color:Liquid
