JNK
Las JNK (c-Jun N-terminal kinases) son un subgrupo de la familia MAPK que responden a estímulos de estrés, como citoquinas, radiación ultravioleta y choque térmico, y están involucradas en el control de la apoptosis, la inflamación y las respuestas inmunitarias. La señalización de JNK es crucial para la regulación de las respuestas celulares al estrés y se ha implicado en diversas enfermedades, incluidas las neurodegenerativas, el cáncer y las afecciones inflamatorias. En CymitQuimica, ofrecemos una gama de moduladores de la vía JNK para apoyar su investigación en señalización de estrés, apoptosis y patología de enfermedades.
Se han encontrado 96 productos de "JNK"
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SU3327
CAS:<p>SU3327 (halicin) is a potent, selective and substrate-competitive inhibitor of JNK(IC50 of 0.7 μM).</p>Fórmula:C5H3N5O2S3Pureza:98.39%Forma y color:SolidPeso molecular:261.3Urolithin B
CAS:<p>Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical</p>Fórmula:C13H8O3Pureza:99.45%Forma y color:SolidPeso molecular:212.2Mefloquine
CAS:<p>Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor.</p>Fórmula:C17H16F6N2OPureza:99.89%Forma y color:SolidPeso molecular:378.31Tanzisertib
CAS:<p>Tanzisertib (CC-930) (CC-930) is a potent inhibitor of JNK1/2/3 with IC50s of 61/7/6 nM, respectively, with potential antifibrotic activity.</p>Fórmula:C21H23F3N6O2Pureza:98.66% - 99.28%Forma y color:SolidPeso molecular:448.44NBDHEX
CAS:<p>NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1).</p>Fórmula:C12H15N3O4SPureza:97.38%Forma y color:SolidPeso molecular:297.33Metacetamol
CAS:<p>Metacetamol, a non-toxic acetaminophen derivative, is an OTC analgesic/antipyretic and synthesis intermediate.</p>Fórmula:C8H9NO2Pureza:99.76% - 99.90%Forma y color:Physical Description Light Gray Solid (Ntp 1992)Peso molecular:151.16Mefloquine hydrochloride
CAS:<p>Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.</p>Fórmula:C17H17ClF6N2OPureza:99% - 99.74%Forma y color:Off-White To Yellow SolidPeso molecular:414.77JNK-IN-13
CAS:<p>JNK-IN-13 is a JNK inhibitor that inhibits JNK3 and JNK2 and can be used in the study of diabetes, inflammation, and neurological disorders.</p>Fórmula:C13H7ClN4SPureza:98.74%Forma y color:SolidPeso molecular:286.74Chloramphenicol
CAS:<p>Chloramphenicol (Chloromycetin) is a broad-spectrum antibiotic that inhibits the biosynthesis of bacterial proteins. Cost-effective and quality-assured.</p>Fórmula:C11H12Cl2N2O5Pureza:99.6% - 99.84%Forma y color:Needles Or Elongated Plates From Water Or Ethylene Dichloride SolidPeso molecular:323.13SP 600125, negative control
CAS:<p>SP 600125, negative control is a methylated analog of SP 600125 and can be used as a negative control for SP 600125.</p>Fórmula:C15H10N2OPureza:≥98%Forma y color:SolidPeso molecular:234.25JNK-IN-18
<p>JNK-IN-18 (compound 23b) is a potent inhibitor of JNK1, boasting an IC50 of 2 nM. It demonstrates superior efficacy when compared to its IC50 values of 125 nM for JNK2 and 98 nM for BRAF(V600E).</p>Forma y color:Odour SolidAS601245.2TFA (345987-15-7 free base)
CAS:<p>AS601245.2TFA (345987-15-7 free base) (AS601245.2TFA) is a cell-permeable Inhibitor of JNK (IC50s of 150, 220, and 70 nM for hJNK1, hJNK2, and hJNK3,</p>Fórmula:C24H18F6N6O4SPureza:98%Forma y color:SoildPeso molecular:600.50JNK-1-IN-3
CAS:<p>JNK-1-IN-3 (Compound 9e) downregulates JNK1 and phosphorylated JNK1, reduces c-Jun and c-Fos expression in tumours, and restores p53 activity.</p>Fórmula:C19H17FN4O3Pureza:97.551%Forma y color:SolidPeso molecular:368.36D-JBD19
CAS:<p>D-JBD19 is a non-permeable peptide with neuroprotective effects.</p>Fórmula:C99H164N32O28Pureza:98%Forma y color:SolidPeso molecular:2250.597L-JNKI-1
<p>L-JNKI-1 is a cell-permeable peptide inhibitor specific for JNK, it has been shown to effectively inhibit JNK activity in in vivo studies.</p>Fórmula:C164H286N66O40Pureza:98%Forma y color:SolidPeso molecular:3822.44JNK3 inhibitor-7
<p>Potent, oral JNK3 inhibitor-7 crosses blood-brain barrier, IC50: 53 nM (JNK3), offers neuroprotection, potential in AD research.</p>Fórmula:C32H31N7O3Forma y color:SolidPeso molecular:561.63OVA-E1 peptide
CAS:<p>OVA-E1 peptide, as SIINFEKL variant, triggers similar p38/JNK activation in mutant and normal thymocytes.</p>Fórmula:C47H76N10O14Forma y color:SolidPeso molecular:1005.181MAP4K4-IN-6
<p>MAP4K4-IN-6 (Compound 15f) is a MAP4K4 inhibitor with an IC50 of 80 nM. It reduces the phosphorylation of c-Jun and exhibits neuroprotective effects. Additionally, MAP4K4-IN-6 enhances the vitality of motor neurons and can be utilized in the study of amyotrophic lateral sclerosis (ALS).</p>Forma y color:Odour SolidJNK3 inhibitor-8
<p>JNK3 inhibitor-8: potent, selective, oral, BBB-penetrating, IC50: JNK3=21 nM, JNK2=2203 nM, JNK1>10,000 nM; potential in Alzheimer's research.</p>Fórmula:C32H30FN7O3Forma y color:SolidPeso molecular:579.62CC-401
CAS:<p>CC-401 is a specific inhibitor of JNK (Ki: 25-50nM).</p>Fórmula:C22H24N6OPureza:98%Forma y color:SolidPeso molecular:388.47
