Ras
Las proteínas Ras son pequeñas GTPasas que actúan como interruptores moleculares en la vía de señalización MAPK, controlando el crecimiento, la diferenciación y la supervivencia celular. Ras activado inicia una cascada de señalización que incluye Raf, MEK y ERK, lo que lleva a diversas respuestas celulares. Las mutaciones en los genes Ras son comunes en el cáncer, lo que convierte a Ras en un enfoque importante de la investigación oncológica. En CymitQuimica, ofrecemos una gama de moduladores de Ras para apoyar su investigación en biología del cáncer, transducción de señales y desarrollo terapéutico.
Se han encontrado 166 productos para "Ras".
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MAPK Inhibitor Library
A unique collection of 365 compounds targeting MAPK signaling for drug discovery in MAPK related diseases;Forma y color:Odour SolidRef: TM-L1400
1mgA consultar10μL*10mM (DMSO)A consultar20μL*10mM (DMSO)A consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarMC 976
CAS:MC 976 is a derivative of Vitamin D3.Fórmula:C27H42O3Pureza:98%Forma y color:SolidPeso molecular:414.63BI1701963
BI1701963 is an orally effective inhibitor that targets the SOS1 and KRAS interaction, specifically inhibiting the activation of KRAS by blocking its GTP loading. This compound is utilized in cancer research to explore potential therapeutic effects against KRAS-driven malignancies.Fórmula:C47H62N8O4SForma y color:SolidPeso molecular:835.11FAM49B (190-198) mouse
CAS:FAM49B (190-198) mouse represents a peptide fragment of the mitochondria-localized protein FAM49B, which is instrumental in regulating mitochondrial fission, function, and integrity, in addition to influencing tumor progression. Beyond its role in mitochondrial dynamics, FAM49B serves as a negative regulator of T cell activation by inhibiting GTPase Rac activity and affecting cytoskeleton reorganization.Fórmula:C49H71N9O14SForma y color:SolidPeso molecular:1042.2Rapaprutug
CAS:Rapaprutug is a monoclonal antibody that targets human KARS1 (lysyl-tRNA synthetase 1). It can block inflammation-related signaling pathways involving KARS1, thereby reducing the production and release of inflammatory factors. Rapaprutug shows potential for research into inflammatory diseases.Forma y color:LiquidSevelamer Carbonate
CAS:Sevelamer carbonate, a non-absorbed polymer, binds phosphate with carbonate instead of chloride.Fórmula:(C3H7N·C3H5ClO)x·xH2CO3Pureza:98%Forma y color:Yellow SolidPeso molecular:211.64FTI-277 hydrochloride
CAS:FTI-277 HCl: potent FTase inhibitor, IC50 500 pM, 100x more selective than GGTase I.Fórmula:C22H30ClN3O3S2Pureza:97.57% - 97.61%Forma y color:SolidPeso molecular:484.07Ref: TM-T2700
1mg50,00€2mg70,00€5mg90,00€1mL*10mM (DMSO)102,00€10mg158,00€25mg304,00€50mg497,00€100mg708,00€200mg964,00€APS6-45
CAS:APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity.Fórmula:C23H16F8N4O3Pureza:99.39%Forma y color:White SolidPeso molecular:548.39Ref: TM-T8843
2mg37,00€5mg84,00€1mL*10mM (DMSO)92,00€10mg120,00€25mg236,00€50mg380,00€100mg583,00€200mg785,00€ZT-12-037-01
CAS:Zt-12-037-01 is a ATP competitive STK19 inhibitor（IC50 values of 23.96 nM and 27.94 nM for STK19 (WT) and STK19 (D89N),respectively).Fórmula:C21H31N5O2Pureza:99.56%Forma y color:SolidPeso molecular:385.51A-116
CAS:1A-116 is a specific Rac1 inhibitor.Fórmula:C16H16F3N3Pureza:99.71%Forma y color:SolidPeso molecular:307.31Ref: TM-T14004
1mg52,00€5mg105,00€1mL*10mM (DMSO)116,00€10mg158,00€25mg268,00€50mg421,00€100mg620,00€200mg875,00€Adagrasib
CAS:View and buy Adagrasib (MRTX849) from TargetMol.MRTX849 is a potent, selective and covalent KRASG12C inhibitor with potential antineoplastic activity. Cited in 2 publications.Fórmula:C32H35ClFN7O2Pureza:99.10% - 99.9%Forma y color:SolidPeso molecular:604.12ML-097
CAS:ML-097 (CID-2160985) is a pan activator of Ras-related GTPasesFórmula:C14H11BrO3Pureza:99.12%Forma y color:SolidPeso molecular:307.139Ref: TM-T21970
5mg62,00€1mL*10mM (DMSO)67,00€10mg90,00€25mg133,00€50mg192,00€100mg286,00€500mg687,00€ARS-1620
CAS:ARS-1620 is a covalent inhibitor of K-RASG12C.Fórmula:C21H17ClF2N4O2Pureza:98.86%Forma y color:White SolidPeso molecular:430.84Kobe0065
CAS:Kobe0065: novel small-molecule, inhibits Ras–Raf, Ki=46±13 μM, blocks H-Ras·GTP/c-Raf-1 RBD binding.Fórmula:C15H11ClF3N5O4SPureza:98% - >99.99%Forma y color:SolidPeso molecular:449.79ML141
CAS:ML141 (CID-2950007) is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM).Fórmula:C22H21N3O3SPureza:99.36% - 99.56%Forma y color:SolidPeso molecular:407.49Ref: TM-T2463
1mg37,00€2mg52,00€5mg69,00€1mL*10mM (DMSO)71,00€10mg101,00€25mg200,00€50mg321,00€100mg515,00€SCH54292
CAS:SCH-54292 is a GDP exchange inhibitor.Fórmula:C24H28N2O9SPureza:95.65%Forma y color:SolidPeso molecular:520.55K-Ras(G12C) inhibitor 9
CAS:K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C).Fórmula:C16H21ClIN3O4SPureza:97.33% - 97.45%Forma y color:SolidPeso molecular:513.78Ref: TM-T6556
1mg34,00€5mg78,00€10mg108,00€1mL*10mM (DMSO)108,00€25mg215,00€50mg311,00€100mg425,00€200mg597,00€Rhosin hydrochloride
CAS:Rhosin hydrochloride is a specific inhibitor of the RhoA subfamily Rho GTPases.Cost-effective and quality-assured.Fórmula:C20H20Cl2N6OPureza:97.51% - 98.92%Forma y color:SolidPeso molecular:431.318BAY-293
CAS:BAY-293 is a potent, cell-active SOS1 inhibitor that disrupts the KRAS-SOS1 interaction (IC50: 21 nM).Fórmula:C25H28N4O2SPureza:97.16%Forma y color:SolidPeso molecular:448.58Ref: TM-T5418
1mg50,00€5mg105,00€1mL*10mM (DMSO)116,00€10mg177,00€25mg321,00€50mg482,00€100mg710,00€200mg982,00€(Rac)-Antineoplaston A10
CAS:Antineoplaston A10 is the first identified human antineoplaston, naturally occurring with anti-proliferative properties.Fórmula:C13H14N2O3Pureza:98.41%Forma y color:White SolidPeso molecular:246.26Ref: TM-T5379
1mg38,00€5mg84,00€1mL*10mM (DMSO)90,00€10mg122,00€25mg198,00€50mg295,00€100mg424,00€200mg593,00€
