Ras
Las proteínas Ras son pequeñas GTPasas que actúan como interruptores moleculares en la vía de señalización MAPK, controlando el crecimiento, la diferenciación y la supervivencia celular. Ras activado inicia una cascada de señalización que incluye Raf, MEK y ERK, lo que lleva a diversas respuestas celulares. Las mutaciones en los genes Ras son comunes en el cáncer, lo que convierte a Ras en un enfoque importante de la investigación oncológica. En CymitQuimica, ofrecemos una gama de moduladores de Ras para apoyar su investigación en biología del cáncer, transducción de señales y desarrollo terapéutico.
Se han encontrado 167 productos para "Ras".
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MAPK Inhibitor Library
A unique collection of xnum cancer cell differentiation inducing compounds for high throughput and high content screening;Forma y color:Odour SolidRef: TM-L1400
1mgA consultar10μL*10mM (DMSO)A consultar20μL*10mM (DMSO)A consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarMC 976
CAS:MC 976 is a derivative of Vitamin D3.Fórmula:C27H42O3Pureza:98%Forma y color:SolidPeso molecular:414.63KRAS inhibitor-33
KRAS inhibitor-33 (compound 115a) is a pyrido[2,3-d]pyrimidine derivative that serves as an effective inhibitor of KRAS, exhibiting an IC50 value of ≤ 100nM.Fórmula:C33H39ClF2N6O3Forma y color:SolidPeso molecular:641.15(E/Z)-ZINC09659342
CAS:(E/Z)-ZINC09659342 is an inhibitor of Lbc-Rho A interaction.Fórmula:C23H15F3N2O4Pureza:>99.99%Forma y color:SolidPeso molecular:440.37Ref: TM-T9986
1mg47,00€5mg96,00€1mL*10mM (DMSO)105,00€10mg152,00€25mg250,00€50mg354,00€100mg477,00€200mg622,00€TAT-PAK18 R192A
TAT-PAK18 R192A is an inactive Tat-Pak peptide. It does not influence Rac1 translocation triggered by any tested proteins.Fórmula:C143H247N55O37Peso molecular:3326.91369Sevelamer Carbonate
CAS:Sevelamer carbonate, a non-absorbed polymer, binds phosphate with carbonate instead of chloride.Fórmula:(C3H7N·C3H5ClO)x·xH2CO3Pureza:98%Forma y color:Yellow SolidPeso molecular:211.64FTI-277 hydrochloride
CAS:FTI-277 HCl: potent FTase inhibitor, IC50 500 pM, 100x more selective than GGTase I.Fórmula:C22H30ClN3O3S2Pureza:97.57% - 97.61%Forma y color:SolidPeso molecular:484.07Ref: TM-T2700
1mg50,00€2mg70,00€5mg90,00€1mL*10mM (DMSO)102,00€10mg158,00€25mg304,00€50mg497,00€100mg708,00€200mg964,00€APS6-45
CAS:APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity.Fórmula:C23H16F8N4O3Pureza:99.39%Forma y color:White SolidPeso molecular:548.39Ref: TM-T8843
2mg37,00€5mg84,00€1mL*10mM (DMSO)92,00€10mg120,00€25mg236,00€50mg380,00€100mg583,00€200mg785,00€Rhosin hydrochloride
CAS:Rhosin hydrochloride is a specific inhibitor of the RhoA subfamily Rho GTPases.Cost-effective and quality-assured.Fórmula:C20H20Cl2N6OPureza:97.51% - 98.92%Forma y color:SolidPeso molecular:431.318SCH54292
CAS:SCH-54292 is a GDP exchange inhibitor.Fórmula:C24H28N2O9SPureza:95.65%Forma y color:SolidPeso molecular:520.55ML-097
CAS:ML-097 (CID-2160985) is a pan activator of Ras-related GTPasesFórmula:C14H11BrO3Pureza:99.12%Forma y color:SolidPeso molecular:307.139Ref: TM-T21970
5mg62,00€1mL*10mM (DMSO)67,00€10mg90,00€25mg133,00€50mg192,00€100mg286,00€500mg687,00€ZCL278
CAS:ZCL278 is a selective Cdc42 GTPase inhibitor.Fórmula:C21H19BrClN5O4S2Pureza:96.29% - 99.72%Forma y color:SolidPeso molecular:584.89Ref: TM-T1855
5mg52,00€1mL*10mM (DMSO)63,00€10mg74,00€25mg129,00€50mg210,00€100mg294,00€200mg470,00€500mg763,00€ARS-1620
CAS:ARS-1620 is a covalent inhibitor of K-RASG12C.Fórmula:C21H17ClF2N4O2Pureza:98.86%Forma y color:White SolidPeso molecular:430.84Kobe0065
CAS:Kobe0065: novel small-molecule, inhibits Ras–Raf, Ki=46±13 μM, blocks H-Ras·GTP/c-Raf-1 RBD binding.Fórmula:C15H11ClF3N5O4SPureza:98% - >99.99%Forma y color:SolidPeso molecular:449.79ML141
CAS:ML141 (CID-2950007) is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM).Fórmula:C22H21N3O3SPureza:99.36% - 99.56%Forma y color:SolidPeso molecular:407.49Ref: TM-T2463
1mg37,00€2mg52,00€5mg69,00€1mL*10mM (DMSO)71,00€10mg101,00€25mg200,00€50mg321,00€100mg515,00€ZT-12-037-01
CAS:Zt-12-037-01 is a ATP competitive STK19 inhibitor（IC50 values of 23.96 nM and 27.94 nM for STK19 (WT) and STK19 (D89N),respectively).Fórmula:C21H31N5O2Pureza:99.56%Forma y color:White SolidPeso molecular:385.51A-116
CAS:1A-116 is a specific Rac1 inhibitor.Fórmula:C16H16F3N3Pureza:99.71%Forma y color:SolidPeso molecular:307.31Ref: TM-T14004
1mg52,00€5mg105,00€1mL*10mM (DMSO)116,00€10mg158,00€25mg268,00€50mg421,00€100mg620,00€200mg875,00€(Rac)-Antineoplaston A10
CAS:Antineoplaston A10 is the first identified human antineoplaston, naturally occurring with anti-proliferative properties.Fórmula:C13H14N2O3Pureza:98.41%Forma y color:White SolidPeso molecular:246.26RBC8
CAS:RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras.Fórmula:C25H20N4O3Pureza:98.44% - 99.81%Forma y color:White SolidPeso molecular:424.45Ref: TM-T6634
1mg46,00€1mL*10mM (DMSO)92,00€5mg96,00€10mg147,00€25mg281,00€50mg447,00€100mg650,00€200mg888,00€EHop-016
CAS:EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.Fórmula:C25H30N6OPureza:98.99% - >99.99%Forma y color:SolidPeso molecular:430.55Ref: TM-T2427
5mg46,00€1mL*10mM (DMSO)49,00€10mg70,00€25mg120,00€50mg202,00€100mg316,00€200mg467,00€500mg747,00€
