ERK
ERK es una proteína clave en la vía de señalización MAPK (Mitogen-Activated Protein Kinase), que está involucrada en la transmisión de señales desde los receptores de la superficie celular hasta el ADN en el núcleo celular. ERK juega un papel crucial en la regulación de varios procesos celulares, incluyendo la proliferación, diferenciación y supervivencia. La desregulación de la señalización ERK está asociada con el desarrollo de cáncer y otras enfermedades, lo que la convierte en un objetivo importante para la intervención terapéutica. En CymitQuimica, ofrecemos una selección de inhibidores y moduladores de ERK de alta calidad para apoyar su investigación en señalización celular, oncología y desarrollo terapéutico.
Se han encontrado 205 productos de "ERK"
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Tenuifoliside A
CAS:Tenuifoliside A has anti-apoptotic , neuroprotective activity.Fórmula:C31H38O17Pureza:98.99% - 99.91%Forma y color:SolidPeso molecular:682.62BAY885
CAS:BAY885 is a new ERK5 inhibitor.Fórmula:C25H28F3N7O2Pureza:99.83%Forma y color:SolidPeso molecular:515.53Mogrol
CAS:Mogrol, a biometabolite of mogrosides, functions by inhibiting the ERK1/2 and STAT3 pathways, diminishing CREB activation, and activating AMPK signaling.Fórmula:C30H52O4Pureza:99.85% - 99.90%Forma y color:SolidPeso molecular:476.73Temuterkib
CAS:LY3214996 (Temuterkib) is a potent oral ERK1/2 inhibitor with potential cancer-fighting properties.
Fórmula:C22H27N7O2SPureza:99.57% - >99.99%Forma y color:SolidPeso molecular:453.56GPR34 receptor antagonist 2
CAS:GPR34 receptor antagonist 2 (Tyrosine, N-[(2E)-3-(4'-chloro[1,1'-biphenyl]-4-yl)-1-oxo-2-propen-1-yl]-O-(phenylmethyl)-) is an anti-inflammatory agent.Fórmula:C31H26ClNO4Pureza:97.26%Forma y color:SolidPeso molecular:512Ref: TM-T8848
1mg116,00€5mg274,00€10mg449,00€25mg738,00€50mg1.035,00€100mg1.388,00€500mg2.783,00€1mL*10mM (DMSO)304,00€ERK5-IN-1
CAS:ERK5-IN-1 is a potent ERK5 inhibitor (IC50: 87 nM). It also inhibits LRRK2[G2019S] (IC50: 26 nM).Fórmula:C25H29N7O2Pureza:97.70%Forma y color:SolidPeso molecular:459.54Tauroursodeoxycholate
CAS:Tauroursodeoxycholate (UR 906), a hydrophilic bile acid, low in humans, may treat PBC, insulin resistance, and ALS.Fórmula:C26H45NO6SPureza:98.77% - 99.93%Forma y color:White SolidPeso molecular:499.7Loureirin B
CAS:Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.Fórmula:C18H20O5Pureza:99.33% - 99.86%Forma y color:SolidPeso molecular:316.35UNC569
CAS:UNC569 selectively inhibits kidney URAT1, regulating uric acid excretion and aiding gout patient's uric balance.Fórmula:C22H29FN6Pureza:98.91% - 99.67%Forma y color:SolidPeso molecular:396.5DEL-22379
CAS:DEL-22379 is a water-soluble ERK dimerization inhibitor with IC50 of ～0.5 μM.Fórmula:C26H28N4O3Pureza:99.3% - 99.53%Forma y color:SolidPeso molecular:444.532,5-Dihydroxyacetophenone
CAS:2,5-Dihydroxyacetophenone has anti-anxiety, neuroprotective, anti-inflammatory properties, and modulates cell signaling and melanogenesis.Fórmula:C8H8O3Pureza:99.75%Forma y color:Yellow PowderPeso molecular:152.15Butein
CAS:Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.Fórmula:C15H12O5Pureza:98.76% - >99.99%Forma y color:SolidPeso molecular:272.25Ref: TM-T6427
1mg40,00€2mg52,00€5mg84,00€10mg101,00€25mg202,00€50mg326,00€100mg520,00€1mL*10mM (DMSO)82,00€Pachymic acid
CAS:Pachymic acid (3-O-Acetyltumulosic acid) is a natural product, and inhibits Akt and ERK signaling pathways.Fórmula:C33H52O5Pureza:99.39% - >99.99%Forma y color:White PowderPeso molecular:528.76β-Neoendorphin acetate(77739-21-0 free base)
CAS:beta-Neoendorphin acetate is an agonist of κ-opioid receptorFórmula:C56H81N13O14Pureza:99.91%Forma y color:SolidPeso molecular:1160.34GRK5-IN-2
CAS:GRK5-IN-2, a pyridine-based bicyclic compound, is a potent G-protein-coupled receptor kinase 5 (GRK5) inhibitor.Fórmula:C20H20N4O4Pureza:99.92%Forma y color:SolidPeso molecular:380.4Ref: TM-T9609
2mg34,00€5mg52,00€10mg75,00€25mg138,00€50mg215,00€100mg318,00€200mg444,00€1mL*10mM (DMSO)52,00€6-OAU
CAS:6-OAU is a GPR84 agonist, activates it in HEK293 cells with a 105 nM EC50.Fórmula:C12H21N3O2Pureza:98.14% - 99.01%Forma y color:SolidPeso molecular:239.31Ref: TM-T2036
1mg160,00€2mg215,00€5mg329,00€10mg472,00€25mg753,00€50mg1.074,00€100mg1.444,00€1mL*10mM (DMSO)301,00€Nitidine chloride
CAS:1.Fórmula:C21H18ClNO4Pureza:96.59% - 99.55%Forma y color:SolidPeso molecular:383.82XMD17-109
CAS:XMD17-109 (ERK5-IN-1) is a new selective ERK-5 inhibitor (EC50: 4.2 uM, HEK293 cells).
Fórmula:C36H46N8O3Pureza:98.75% - 99.7%Forma y color:SolidPeso molecular:638.8DCLK1-IN-1
CAS:DCLK1-IN-1 is a selective, in vivo compatible chemical probe of the kinase domain of doublecortin-like kinase 1 (DCLK1).Cost-effective and quality-assured.
Fórmula:C26H28F3N7O2Pureza:98.55% - 99.28%Forma y color:SolidPeso molecular:527.54Ref: TM-T8418
2mg139,00€5mg207,00€10mg354,00€25mg587,00€50mg835,00€100mg1.149,00€200mg1.549,00€1mL*10mM (DMSO)265,00€AG126
CAS:AG126 (Tyrphostin AG126) selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42). AG-126 weakly inhibits epidermal GFRK and platelet-derived GFRK.Fórmula:C10H5N3O3Pureza:97.35%Forma y color:SolidPeso molecular:215.16
