ERK
ERK es una proteína clave en la vía de señalización MAPK (Mitogen-Activated Protein Kinase), que está involucrada en la transmisión de señales desde los receptores de la superficie celular hasta el ADN en el núcleo celular. ERK juega un papel crucial en la regulación de varios procesos celulares, incluyendo la proliferación, diferenciación y supervivencia. La desregulación de la señalización ERK está asociada con el desarrollo de cáncer y otras enfermedades, lo que la convierte en un objetivo importante para la intervención terapéutica. En CymitQuimica, ofrecemos una selección de inhibidores y moduladores de ERK de alta calidad para apoyar su investigación en señalización celular, oncología y desarrollo terapéutico.
Se han encontrado 205 productos de "ERK"
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ASP2453
CAS:ASP2453 is a potent, selective and covalent inhibitor of KRAS G12C.Fórmula:C40H48F3N7O4Pureza:99.71%Forma y color:SolidPeso molecular:747.85Epieriocalyxin A
CAS:Epieriocalyxin A can suppress Caco-2 colon cancer cell growth. It could be a potential drug for colon cancer therapy in the future.Fórmula:C20H24O5Pureza:97.00%Forma y color:SolidPeso molecular:344.4Avatrombopag maleate
CAS:Avatrombopag (AKR-501/E5501) is an oral TPO receptor agonist for thrombocytopenia treatment, approved in 2018.Fórmula:C33H38Cl2N6O7S2Forma y color:SolidPeso molecular:765.72DMU-212
CAS:DMU-212, a Resveratrol derivative, has antimitotic, antiproliferative, antioxidant properties; induces apoptosis via ERK1/2.
Fórmula:C18H20O4Pureza:99.86%Forma y color:SolidPeso molecular:300.35SUN11602
CAS:SUN11602, an aniline compound, mimics the neuroprotective mechanisms of basic fibroblast growth factor.Fórmula:C26H37N5O2Pureza:99.36%Forma y color:SolidPeso molecular:451.6RU-301
CAS:RU-301 is a novel pan-tam inhibitorFórmula:C21H19F3N4O4SPureza:98.87%Forma y color:SolidPeso molecular:480.46Ref: TM-T7425
1mg98,00€5mg222,00€10mg344,00€25mg587,00€50mg803,00€100mg1.063,00€1mL*10mM (DMSO)241,00€ERK-IN-3
CAS:ERK-IN-3 (ASN007 free base) is a potent and orally active inhibitor of ERK.Fórmula:C22H25ClFN7O2Pureza:99.55% - 99.76%Forma y color:SolidPeso molecular:473.93Methylnissolin
CAS:Methylnissolin (3-Hydroxy-9,10-dimethoxyptercarpan) is derived from Astragalus and has antibacterial and anti-cancer effects.Fórmula:C17H16O5Pureza:99.68% - 99.98%Forma y color:SolidPeso molecular:300.31EF24
CAS:EF24 treatment boosts caspase 3/9 activity, hinders MEK1/ERK phosphorylation, and exhibits strong anti-tumor effects in OSCC by deactivating MAPK/ERK.Fórmula:C19H15F2NOPureza:99.71%Forma y color:SolidPeso molecular:311.33Ref: TM-T27242
1g1.510,00€1mg40,00€5mg85,00€10mg133,00€25mg235,00€50mg354,00€100mg533,00€500mg1.130,00€1mL*10mM (DMSO)93,00€Deltonin
CAS:Deltonin inhibits ERK1/2 & AKT; toxic to HepG2 (IC50: 7.66μM), C26 (IC50: 1.22μM), MDA-MB-231 cells (IC50: 1.58μM).Fórmula:C45H72O17Pureza:98.77% - 99.79%Forma y color:SolidPeso molecular:885.04trans-Zeatin
CAS:trans-Zeatin ((E)-Zeatin) is the member of the plant growth hormone family known as cytokinins, which regulate cell division, development, and nutrientFórmula:C10H13N5OPureza:97.13% - 98.96%Forma y color:White To Light Yellow Crystal PowderPeso molecular:219.24Ref: TM-TMS2181
10mg37,00€25mg52,00€50mg66,00€100mg96,00€200mg128,00€500mg205,00€1mL*10mM (DMSO)33,00€Ravoxertinib
CAS:Ravoxertinib (GDC-0994) is an effective and orally available ERK1/2 inhibitor (IC50: 1.1/0.3 nM).Fórmula:C21H18ClFN6O2Pureza:98% - 99.87%Forma y color:SolidPeso molecular:440.86Ref: TM-T6511
1mg38,00€2mg49,00€5mg80,00€10mg90,00€25mg164,00€50mg268,00€100mg399,00€1mL*10mM (DMSO)88,00€Bohemine
CAS:Bohemine is a cyclin-dependent kinase inhibitor.Fórmula:C18H24N6OPureza:99.09% - 99.53%Forma y color:SolidPeso molecular:340.42Prosaptide TX14(A) acetate
Prosaptide TX14(A) acetate is a potent GPR37L1 and GPR37 agonist. Prosaptide Tx14(A) TFA increases both ERK1 and ERK2 phosphorylation in Schwann cells.Fórmula:C71H114N16O28Pureza:95.29%Forma y color:SolidPeso molecular:1639.76Tauroursodeoxycholate sodium
CAS:Tauroursodeoxycholate sodium (TUDC) is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis.Fórmula:C26H44NNaO6SPureza:97.90%Forma y color:SolidPeso molecular:521.69FR 180204
CAS:FR 180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2.Fórmula:C18H13N7Pureza:98% - 99.74%Forma y color:SolidPeso molecular:327.34Ref: TM-T1956
1mg43,00€2mg55,00€5mg86,00€10mg138,00€25mg221,00€50mg331,00€100mg497,00€1mL*10mM (DMSO)94,00€MRTX1133
CAS:View and buy MRTX1133 from TargetMol.MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS G12D.Fórmula:C33H31F3N6O2Pureza:97.39% - 99.6%Forma y color:SolidPeso molecular:600.63Ref: TM-T9303
1mg177,00€5mg379,00€10mg580,00€25mg893,00€50mg1.251,00€100mg1.639,00€200mg2.215,00€1mL*10mM (DMSO)502,00€KO-947
CAS:KO-947 is a potent and specific inhibitor of ERK1/2 kinases.
Fórmula:C21H17N5OPureza:97.84%Forma y color:SolidPeso molecular:355.39AZD8330
CAS:AZD8330 (ARRY-704) is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 nM. Phase 1.Fórmula:C16H17FIN3O4Pureza:98.72%Forma y color:SolidPeso molecular:461.23(E/Z)-BIX02188
CAS:BIX02188 inhibits MEK5 (IC50: 4.3 nM) and ERK5 (810 nM) but not MEK1/2, JNK2, or ERK2.Fórmula:C25H24N4O2Pureza:97.39% - 98.38%Forma y color:SolidPeso molecular:412.48Ref: TM-T6324
1mg50,00€2mg66,00€5mg126,00€10mg229,00€25mg344,00€50mg517,00€100mg745,00€1mL*10mM (DMSO)143,00€
