ERK
ERK es una proteína clave en la vía de señalización MAPK (Mitogen-Activated Protein Kinase), que está involucrada en la transmisión de señales desde los receptores de la superficie celular hasta el ADN en el núcleo celular. ERK juega un papel crucial en la regulación de varios procesos celulares, incluyendo la proliferación, diferenciación y supervivencia. La desregulación de la señalización ERK está asociada con el desarrollo de cáncer y otras enfermedades, lo que la convierte en un objetivo importante para la intervención terapéutica. En CymitQuimica, ofrecemos una selección de inhibidores y moduladores de ERK de alta calidad para apoyar su investigación en señalización celular, oncología y desarrollo terapéutico.
Se han encontrado 223 productos para "ERK".
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Prosaptide TX14(A) acetate
Prosaptide TX14(A) acetate is a potent GPR37L1 and GPR37 agonist. Prosaptide Tx14(A) TFA increases both ERK1 and ERK2 phosphorylation in Schwann cells.Fórmula:C71H114N16O28Pureza:95.29%Forma y color:SolidPeso molecular:1639.76Aurothiomalate sodium
CAS:Sodium aurothiomalate (Miochrysin) inhibits PKC-ι, TrxR; used as an anti-rheumatic and has anti-tumor properties.Fórmula:C4H3AuNa2O4SPureza:99.66%Forma y color:SolidPeso molecular:390.07Ref: TM-T20168
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar200mgA consultarSC99
CAS:SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.Fórmula:C15H8Cl2FN3OPureza:99.56%Forma y color:Yellow SolidPeso molecular:336.15Yoda 1
CAS:Yoda 1 is an agonist of the Piezo1 channel that agonizes human- and mouse-derived Piezo1. Yoda 1 is also an inhibitor of GlyT2. Cost-effective, quality assurance.Fórmula:C13H8Cl2N4S2Pureza:98% - 99.98%Forma y color:SolidPeso molecular:355.27Ref: TM-T7506
1mg44,00€2mg57,00€1mL*10mM (DMSO)88,00€5mg90,00€10mg109,00€25mg219,00€50mg424,00€100mg620,00€500mg1.314,00€ERK5-IN-2
CAS:ERK5-IN-2 is an orally active, sub-micromolar, selective ERK5 inhibitor with IC50s of 0.82 μM, 3 μM for ERK5 and ERK5 MEF2D, respectively.Fórmula:C17H11BrFN3O2Pureza:99.01%Forma y color:SolidPeso molecular:388.19Ref: TM-T5535
1mg46,00€5mg90,00€1mL*10mM (DMSO)101,00€10mg160,00€25mg268,00€50mg401,00€100mg580,00€200mg798,00€Asperulosidic acid
CAS:Asperulosidic acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities. ASPA is related to the inhibition of inflammatory cytokines.Fórmula:C18H24O12Pureza:99.47%Forma y color:SolidPeso molecular:432.38Ref: TM-TN1410
1mg120,00€2mg170,00€5mg260,00€1mL*10mM (DMSO)286,00€10mg432,00€25mg708,00€50mg964,00€100mg1.288,00€CAFESTOL
CAS:Cafestol, an ERK inhibitor, suppresses PGE2 and COX-2 by blocking NF-kB in LPS-stimulated RAW264.7 cells.Fórmula:C20H28O3Pureza:97.06% - 99.08%Forma y color:Yellow SolidPeso molecular:316.43Sulforaphene
CAS:Sulforaphene, from radish seeds, aids cancer cell apoptosis and inhibits migration; has an ED50 for velvetleaf at ~2x10^-4 M.Fórmula:C6H9NOS2Pureza:97.55% - 99.67%Forma y color:Yellow LiquidPeso molecular:175.27Ref: TM-TL0016
1mg34,00€2mg46,00€1mL*10mM (DMSO)65,00€5mg66,00€10mg92,00€25mg167,00€50mg241,00€100mg359,00€200mg525,00€Acalabrutinib
CAS:Acalabrutinib (ACP-196), also known as ACP-196, is an orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity.Fórmula:C26H23N7O2Pureza:98.94% - 99.64%Forma y color:White SolidPeso molecular:465.51Ref: TM-T3626
5mg44,00€1mL*10mM (DMSO)48,00€10mg57,00€25mg78,00€50mg90,00€100mg144,00€200mg215,00€500mg355,00€XMD8-92
CAS:XMD8-92 is an effective and specific BMK1/ERK5 inhibitor (Kd: 80 nM).Fórmula:C26H30N6O3Pureza:98.21%Forma y color:SolidPeso molecular:474.55Triptonide
CAS:Triptonide treats autoimmune diseases, has antileukemic/tumor effects, is anti-inflammatory, and boosts IL-37.Fórmula:C20H22O6Pureza:99.11% - 99.64%Forma y color:Pink SolidPeso molecular:358.39Ref: TM-T5S1058
1mg52,00€2mg74,00€5mg108,00€1mL*10mM (DMSO)133,00€10mg158,00€25mg268,00€50mg409,00€100mg595,00€200mg833,00€Peramivir Trihydrate
CAS:Peramivir Trihydrate (RWJ-270201) is a neuraminidase inhibitor (IC50: 0.09 nM) which prevents normal processing of virus particles such that virus particles areFórmula:C15H28N4O4·3H2OPureza:99.52% - 99.87%Forma y color:SolidPeso molecular:382.45Ulixertinib
CAS:Ulixertinib (VRT752271) (BVD-523, VRT752271) is an effective and reversible ERK1/ERK2 inhibitor. The IC50 of Ulixertinib is less than 0.3 nM for ERK2.Fórmula:C21H22Cl2N4O2Pureza:99.31% - 99.95%Forma y color:SolidPeso molecular:433.33Tauroursodeoxycholate sodium
CAS:Tauroursodeoxycholate sodium (TUDC) is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis.Fórmula:C26H44NNaO6SPureza:97.90%Forma y color:SolidPeso molecular:521.69N-tert-butyl-α-Phenylnitrone
CAS:N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) inhibits COX2 catalytic activity.Fórmula:C11H15NOPureza:99.46% - 99.84%Forma y color:SolidPeso molecular:177.24BAY885
CAS:BAY885 is a new ERK5 inhibitor.Fórmula:C25H28F3N7O2Pureza:99.83%Forma y color:SolidPeso molecular:515.53Mogrol
CAS:Mogrol, a biometabolite of mogrosides, functions by inhibiting the ERK1/2 and STAT3 pathways, diminishing CREB activation, and activating AMPK signaling.Fórmula:C30H52O4Pureza:99.85% - 99.95%Forma y color:Yellow SolidPeso molecular:476.73Temuterkib
CAS:LY3214996 (Temuterkib) is a potent oral ERK1/2 inhibitor with potential cancer-fighting properties.Fórmula:C22H27N7O2SPureza:99.57% - >99.99%Forma y color:SolidPeso molecular:453.56Ref: TM-T4091
1mg57,00€2mg74,00€5mg98,00€1mL*10mM (DMSO)105,00€10mg158,00€25mg330,00€50mg497,00€100mg710,00€SHP389
CAS:SHP389 is a highly effective allosteric inhibitor of SHP2, inhibiting SHP2 and p-ERK, used in cancer research.Fórmula:C23H29ClN8O2Pureza:98.24%Forma y color:SolidPeso molecular:484.98ERK-IN-4
CAS:ERK-IN-4 is a cell-permeable ERK inhibitor with potential antiproliferative effects for the study of diseases caused by immune dysfunction.Fórmula:C14H17ClN2O3SPureza:98.92% - 99.95%Forma y color:SolidPeso molecular:328.814Ref: TM-T36675
1mg46,00€2mg57,00€1mL*10mM (DMSO)92,00€5mg93,00€10mg137,00€25mg219,00€50mg324,00€100mg484,00€
