CFTR
El CFTR es una proteína de canal de cloruro que regula el transporte de iones cloruro y bicarbonato a través de las membranas de las células epiteliales, desempeñando un papel crucial en el mantenimiento del equilibrio de fluidos en los tejidos. Las mutaciones en el gen CFTR conducen a la fibrosis quística, un trastorno genético caracterizado por la producción de moco espeso que puede obstruir las vías respiratorias y provocar graves problemas respiratorios y digestivos. En CymitQuimica, ofrecemos una selección de moduladores de CFTR para apoyar su investigación en fibrosis quística, transporte de iones y trastornos genéticos.
Se han encontrado 64 productos de "CFTR"
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Glibenclamide potassium
CAS:<p>Glibenclamide potassium, a more soluble form of Glibenclamide, exists as anhydrous and hydrate salts.</p>Fórmula:C23H27ClKN3O5SForma y color:SolidPeso molecular:532.09CFTR corrector 2
CAS:<p>CFTR corrector 2 (FDL169) is a novel and potent CFTR corrector for treating cystic fibrosis (CF) patients who carry the F508del mutation.</p>Fórmula:C27H23FN4O4Pureza:99.66%Forma y color:SolidPeso molecular:486.49Lubiprostone
CAS:<p>Lubiprostone (RU-0211), an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic constipation.</p>Fórmula:C20H32F2O5Pureza:97.31% - 98.54%Forma y color:White Odorless Crystals Or Crystalline PowderPeso molecular:390.46IOWH-032
CAS:<p>IOWH-032 (IOWH032) , a synthetic CFTR inhibitor, has been investigated for the treatment of cholera, diarrhea, and secretory diarrhea.</p>Fórmula:C22H15Br2N3O4Pureza:98.92% - ≥95%Forma y color:SolidPeso molecular:545.18KM11060
CAS:<p>KM11060 is a novel corrector of the F508del-CFTR trafficking defect, Correcting F508del-CFTR trafficking, increasing the amount of functional CFTR at the plasma</p>Fórmula:C19H17Cl2N3O2SPureza:98.86%Forma y color:SolidPeso molecular:422.33Icenticaftor
CAS:<p>Icenticaftor (QBW251) is an orally active potentiator of CFTR channel.</p>Fórmula:C12H13F6N3O3Pureza:99.76%Forma y color:SolidPeso molecular:361.24CFTR(inh)-172
CAS:<p>CFTR(inh)-172 (CFTR Inhibitor-172) is a voltage-independent, selective CFTR inhibitor.</p>Fórmula:C18H10F3NO3S2Pureza:98% - 99.72%Forma y color:SolidPeso molecular:409.4Nesolicaftor
CAS:<p>Nesolicaftor (PTI-428) specifically enhances cystic fibrosis transmembrane conductance regulator protein synthesis.</p>Fórmula:C18H18N4O4Pureza:99.79%Forma y color:SolidPeso molecular:354.36Tezacaftor
CAS:<p>Tezacaftor (VX661) is a small molecule that can be used as a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) gene function.</p>Fórmula:C26H27F3N2O6Pureza:98.84% - >99.99%Forma y color:SolidPeso molecular:520.5SRI-41315
CAS:<p>SRI-41315 is an eRF1 degrader that acts as a molecular glue at the ribosomal decoding center.SRI-41315 induces extended pauses at the termination codon.</p>Fórmula:C22H19N3O2Pureza:99.87%Forma y color:SolidPeso molecular:357.41GLPG-3221
CAS:<p>GLPG-3221, a potent oral CFTR corrector for cystic fibrosis treatment, has an EC50 of 105 nM.</p>Fórmula:C30H37F3N2O6Pureza:98%Forma y color:SolidPeso molecular:578.62CFTR corrector 9
CAS:<p>CFTR corrector 9 is a CF modulator used to research cystic fibrosis and related disorders.</p>Fórmula:C16H14N2O4Pureza:98.24%Forma y color:SolidPeso molecular:298.29Posenacaftor
CAS:<p>Posenacaftor (PTI-801) regulates CFTR protein for cystic fibrosis research.</p>Fórmula:C27H27NO5Forma y color:SolidPeso molecular:445.51Posenacaftor sodium
CAS:<p>Posenacaftor (PTI-801) sodium, a CFTR modulator for CF research, corrects CFTR protein folding and trafficking.</p>Fórmula:C27H27NNaO5Forma y color:SolidPeso molecular:468.505Corrector C4
CAS:<p>Corrector C4, a corrector commonly used to study cystic fibrosis mutants, works by alleviating the interaction between CFTR transmembrane domain mutants and</p>Fórmula:C21H17ClN4O2S2Pureza:98.36%Forma y color:SolidPeso molecular:456.97Galicaftor
CAS:<p>ABBV-2222 is a CFTR corrector which is studied for the treatment of cystic fibrosis (CF).</p>Fórmula:C28H21F4NO7Pureza:98%Forma y color:SolidPeso molecular:559.46(R)-Posenacaftor sodium
CAS:<p>(R)-Posenacaftor sodium is a modulator for correcting cystic fibrosis protein folding.</p>Fórmula:C27H27NNaO5Forma y color:SolidPeso molecular:468.505(R)-Olacaftor
CAS:<p>(R)-Olacaftor (VX-440) is a CFTR modulator with promise for researching cystic fibrosis.</p>Fórmula:C29H34FN3O4SForma y color:SolidPeso molecular:539.66Ivacaftor-D9
CAS:<p>CTP-656, a cystic fibrosis transmembrane conductance regulator (CFTR) channel activator, is used potentially for the treatment of cystic fibrosis.</p>Fórmula:C24H19D9N2O3Forma y color:SolidPeso molecular:401.55
