Receptor CGRP
Los receptores de CGRP están involucrados en la transmisión del dolor y la regulación del flujo sanguíneo. El CGRP es un neuropéptido que desempeña un papel crucial en la fisiopatología de la migraña al dilatar los vasos sanguíneos y modular las vías de señalización del dolor. Dirigirse a los receptores de CGRP se ha convertido en un enfoque prometedor en el desarrollo de terapias para la migraña. En CymitQuimica, ofrecemos una gama de moduladores de receptores de CGRP para apoyar su investigación en el manejo del dolor, neurobiología y salud vascular.
Se han encontrado 57 productos para "Receptor CGRP".
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PHM-27 (human) acetate
PHM-27 (human) acetate is the endogenous peptide product of prepro-VIP (human), an agonist of the calcitonin receptor (EC 50 = 11 nM). enhanced insulin secretion.Fórmula:C137H215F3N34O42SPureza:99.20%Forma y color:SolidPeso molecular:3099.44Erenumab
CAS:Erenumab: human antibody blocking CGRP receptors to prevent migraines.Pureza:99.43% (SEC-HPLC) - > 95%Forma y color:Transparent LiquidPeso molecular:146.2 kDa (Predicted)Adrenomedullin (16-31), human
CAS:Adrenomedullin (16-31), human is amino acid residues 16-31 fragment of human adrenomedullin (hADM).Fórmula:C82H129N25O21S2Pureza:98%Forma y color:SolidPeso molecular:1865.19RM2
CAS:RM2 is a GRPr antagonist that selectively binds to GRPr, preventing agonist-induced receptor internalization and inhibiting agonist-triggered intracellular calcium mobilization. RM2 is applicable for research related to prostate cancer.Fórmula:C78H118N20O19Peso molecular:1639.89MK-3207
CAS:MK-3207 is a potent, oral CGRP receptor antagonist with high selectivity for human and monkey receptors, inhibiting blood flow in vivo.Fórmula:C31H29F2N5O3Forma y color:White SolidPeso molecular:557.5905α-CGRP(human)
CAS:Endogenous calcitonin gene-related peptide receptor (CGRP) agonist.Fórmula:C163H267N51O49S2Pureza:98%Forma y color:SolidPeso molecular:3789.33MK-8825
CAS:MK-8825 is a CGRP receptor antagonist.Fórmula:C31H30F2N6O3Forma y color:SolidPeso molecular:572.61α-CGRP, rat
CAS:Endogenous neuropeptide, potent vasodilatorFórmula:C162H262N50O52S2Pureza:98%Forma y color:SolidPeso molecular:3806.25CGRP antagonist 6
CGRP Antagonist 6 (Compound 23) is a potent CGRP receptor antagonist (Ki: 0.84 nM). It is utilized in the study of migraines.Forma y color:Odour SolidAdrenomedullin (1-50), rat
CAS:Rat adrenomedullin (1-50) is a 50-AA peptide; induces arterial vasodilation by activating CGRP1 receptors.Fórmula:C248H381N77O75S5Pureza:98%Forma y color:SolidPeso molecular:5729.5Adrenomedullin (AM) (22-52), human
CAS:Adrenomedullin (ADM) is a 52-aa hypotensive peptide. Adrenomedullin (ADM) has structural similarity with amylin.Fórmula:C159H252N46O48Pureza:98%Forma y color:SolidPeso molecular:3576.04HCGRP-(8-37)
CAS:Rat CGRP-(8-37) (VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF) is a highly selective CGRP receptor antagonistFórmula:C139H230N44O38Pureza:98%Forma y color:SolidPeso molecular:3125.59Calcitonin (human) acetate
CAS:Calcitonin (human) acetate (21215-62-3, free base) is a synthetic polypeptide hormone composed of 32 amino acids.Fórmula:C153H230N40O47S3Pureza:99.46%Forma y color:White SolidPeso molecular:3477.91Calcitonin (human)
CAS:Endogenous calcitonin receptor agonist. Lowers systemic blood calcium levels and inhibits bone resorption.Fórmula:C151H226N40O45S3Pureza:98%Forma y color:White Lyophilized PowderPeso molecular:3417.87Adrenomedullin (AM) (22-52), human TFA
Adrenomedullin (AM) human (22-52) is a truncated NH2 TFA-modified adrenal medullary receptor antagonist.Fórmula:C161H253N46F3O50Pureza:98%Forma y color:SolidPeso molecular:3690.06Calcitonin Gene Related Peptide (CGRP) II, rat
CAS:CGRP II is a potent vasodilator that boosts pancreatic enzyme levels by activating β-cell receptors.Fórmula:C163H267N51O50S2Pureza:98%Forma y color:SolidPeso molecular:3805.31Adrenomedullin (porcine)
CAS:Adrenomedullin (porcine) is a vasodilatory peptide that elicits endothelium-dependent relaxation in rat aorta at an IC50 of 2.4 nM and also induces endothelium-(3R,5R,6S)-Atogepant
(3R,5R,6S)-Atogepant (MK-8031) is a CGRP antagonist enantiomer used in migraine research.Fórmula:C29H23F6N5O3Forma y color:SolidPeso molecular:603.52PHM-27 (human)
CAS:Human-derived peptide, VIP/PHM 27 analog, boosts insulin by targeting calcitonin receptor with an EC50 of 11 nM.Fórmula:C135H214N34O40SPureza:98%Forma y color:SolidPeso molecular:2985.44Adrenomedullin (11-50), rat
CAS:Adrenomedullin 11-50 rat is a peptide, stimulates CGRP1 receptor for vasodilation, used in bone growth research.Fórmula:C194H304N58O59S4Pureza:98%Forma y color:SolidPeso molecular:4521.17
