Canal de sodio
Los canales de sodio son proteínas de membrana esenciales que permiten el paso de iones de sodio (Na+) a través de la membrana celular, generando y propagando señales eléctricas en neuronas, células musculares y otros tejidos excitables. Estos canales son vitales para la iniciación y conducción de potenciales de acción, lo que los hace cruciales en procesos como la transmisión de impulsos nerviosos, la contracción muscular y la función cardíaca. La desregulación de los canales de sodio puede llevar a trastornos neurológicos, arritmias y condiciones de dolor crónico. En CymitQuimica, ofrecemos una variedad de moduladores de canales de sodio para apoyar su investigación en neurobiología, cardiología y manejo del dolor.
Se han encontrado 202 productos de "Canal de sodio"
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λ-Cyhalothrin
CAS:<p>λ-Cyhalothrin (Icon) is a type II synthetic pyrethroid insecticide featuring a high-efficiency, broad-spectrum formula with an α-cyano group.</p>Fórmula:C23H19ClF3NO3Pureza:99.76%Forma y color:SolidPeso molecular:449.85Rimeporide
CAS:<p>Rimeporide (EMD-87580) (EMD-87580) is a potent and selective Sodium hydrogen exchange 1 (NHE-1) inhibitor.</p>Fórmula:C11H15N3O5S2Pureza:97.66%Forma y color:SolidPeso molecular:333.38Flecainide hydrochloride
CAS:<p>Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.</p>Fórmula:C17H21ClF6N2O3Pureza:97.79%Forma y color:SolidPeso molecular:450.81Raxatrigine
CAS:<p>Raxatrigine (CNV 1014802) has been investigated for the treatment of Bipolar Disorder and Bipolar Depression.</p>Fórmula:C18H19FN2O2Pureza:98% - 99.43%Forma y color:SolidPeso molecular:314.35N-Me-aminopyrimidinone9
CAS:<p>N-Me-aminopyrimidinone9 is a sodium channel antagonist</p>Fórmula:C16H21N3OSPureza:99.21%Forma y color:SolidPeso molecular:303.42Levobupivacaine
CAS:<p>Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide.</p>Fórmula:C18H28N2OPureza:99.72%Forma y color:SolidPeso molecular:288.43Propafenone hydrochloride
CAS:<p>Propafenone hydrochloride (Arythmol8) is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial.</p>Fórmula:C21H27NO3·HClPureza:99.67%Forma y color:White SolidPeso molecular:377.9Benzocaine xHCl(94-09-7(free base))
<p>Benzocaine shares a common receptor with all othe rLAs in the voltage-gated Na+ channel(IC50 of 0.8 mM tested with a potential of +30 mV).</p>Fórmula:C9H11NO2·xHClPureza:99.37%Forma y color:SolidPeso molecular:N/AVX-150
CAS:<p>VX-150 is a highly selective NaV1.8 inhibitor relative to the other sodium channel subtypes (>400-fold).</p>Fórmula:C21H17F4N2O7PPureza:97.58%Forma y color:SolidPeso molecular:516.34PF-01247324
CAS:<p>PF-01247324 is a selective and orally bioavailable Nav1.8 channel blocker (IC50: 196 nM).</p>Fórmula:C13H10Cl3N3OPureza:99.22%Forma y color:SolidPeso molecular:330.6PF 05089771
CAS:<p>PF 05089771 is a Selective inhibitor of Nav1.7 (IC50 = 11 nM) that interacts with the voltage-sensor domain of domain IV.</p>Fórmula:C18H12Cl2FN5O3S2Pureza:99.03% - 99.42%Forma y color:SolidPeso molecular:500.35PF-05186462
CAS:<p>PF-05186462 (PF-05150122) is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 21 nM, no significant activity against Nav1.5.</p>Fórmula:C19H10ClF4N5O3S2Pureza:99.10% - 99.37%Forma y color:SolidPeso molecular:531.89Ralfinamide mesylate
CAS:<p>Ralfinamide mesylate (FCE-26742A (mesylate)) is an orally available Na+ channel blocker.</p>Fórmula:C18H23FN2O5SPureza:99.83%Forma y color:SolidPeso molecular:398.45Ajmaline
CAS:<p>Ajmaline, a class Ia anti-arrhythmic, diagnoses Brugada syndrome and treats tachycardia; inhibits cardiac Kv1.5/Kv4.3 channels.</p>Fórmula:C20H26N2O2Pureza:99.67% - 99.87%Forma y color:SolidPeso molecular:326.43ICA-121431
CAS:<p>ICA-121431: a potent Nav1.7 inhibitor (IC50=19 nM for rat), minimal effect on human Nav1.5/Nav1.7.</p>Fórmula:C23H19N3O3S2Pureza:98.06%Forma y color:SolidPeso molecular:449.55(+)-Kavain
CAS:<p>(+)-Kavain ((R)-KAWAIN) is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.</p>Fórmula:C14H14O3Pureza:97% - ≥95%Forma y color:White Fine PowderPeso molecular:230.26Benzamil
CAS:<p>Benzamil blocks ENaC, inhibiting sodium transport (IC50=4 nM) and binds with Kd=5 nM to bovine kidney membranes.</p>Fórmula:C13H14ClN7OPureza:99.79%Forma y color:SolidPeso molecular:319.7520(S)-Ginsenoside Rg3
CAS:<p>20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.</p>Fórmula:C42H72O13Pureza:98.11% - 99.93%Forma y color:SolidPeso molecular:785.01Dronedarone
CAS:<p>Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.</p>Fórmula:C31H44N2O5SPureza:98.85% - 99.58%Forma y color:SolidPeso molecular:556.76Evenamide
CAS:<p>Evenamide (NW-3509) is a sodium channel blocker. Which shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness.</p>Fórmula:C16H26N2O2Pureza:96.74% - 99.15%Forma y color:SolidPeso molecular:278.39
