Caseína quinasa
Las caseína quinasas son una familia de quinasas de proteínas serina/treonina que regulan varios procesos celulares, incluyendo la reparación del ADN, los ritmos circadianos y la transducción de señales. Estas quinasas están involucradas en la fosforilación de numerosas proteínas y están implicadas en enfermedades como el cáncer, los trastornos neurodegenerativos y los síndromes metabólicos. En CymitQuimica, ofrecemos una selección de inhibidores de caseína quinasa para apoyar su investigación en transducción de señales, regulación del ciclo celular y desarrollo terapéutico.
Se han encontrado 137 productos de "Caseína quinasa"
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Ellagic acid
CAS:Ellagic acid (Gallogen), a thickened tetracyclic natural product, is a potent CK2 inhibitor. Ellagic acid is an antioxidant. Cost-effective and quality-assured.Fórmula:C14H6O8Pureza:97.11% - 99.75%Forma y color:Cream Colored Needles From Pyridine 1992)Peso molecular:302.19NMS-P715
CAS:NMS-P715 is a highly selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM).Fórmula:C35H39F3N8O3Pureza:99.84%Forma y color:SolidPeso molecular:676.73Emodin
CAS:Emodin (Frangula emodin) is a selective 11β-HSD1 inhibitor,IC50 of 186 and 86 nM against 11β-HSD1 in humans and mice. High-Quality, Low-Cost!Fórmula:C15H10O5Pureza:98.37% - 99.53%Forma y color:Physical Description Orange Needles Or Powder (Ntp 1992)Peso molecular:270.24Silmitasertib sodium salt
CAS:Silmitasertib sodium salt (CX-4945 sodium salt) is a potent and orally bioavailable, highly selective inhibitor of CK2(IC50 of 1 nM, CK2α).Fórmula:C19H11ClN3NaO2Pureza:99.49% - 99.62%Forma y color:SolidPeso molecular:371.75A-3 hydrochloride
CAS:<p>A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.</p>Fórmula:C12H14Cl2N2O2SPureza:99.32%Forma y color:SolidPeso molecular:321.22Casein Kinase Substrates 3
CAS:Casein Kinase Substrates 3 is a substrate of casein kinase.Fórmula:C85H139N27O35SPureza:98%Forma y color:SolidPeso molecular:2131.24GSK-3β/CK-1δ-IN-1
GSK-3β/CK-1δ-IN-1 (8d) is a dual inhibitor of GSK-3β and CK-1δ that can cross the blood-brain barrier, with IC50 values of 0.77 μM and 0.57 μM, respectively. GSK-3β/CK-1δ-IN-1 (8d) is applicable in neuroblastoma research.Fórmula:C22H17F3N4OForma y color:SolidPeso molecular:410.39QXG-6442
QXG-6442 is a molecular glue degrader targeting CK1α, demonstrating a degradation potency with a DC50 of 5.7 nM and a Dmax of 90%. In the MOLM-14 cell line, QXG-6442 induces antiproliferative effects.Fórmula:C21H17N5O4Forma y color:SolidPeso molecular:403.39Casein kinase 1δ-IN-9
CAS:<p>Casein kinase 1δ-IN-9 is a Quinone reductase 2 inhibitor with IC50 of 0.6μM.</p>Fórmula:C15H12ClN3Pureza:99.93%Forma y color:SolidPeso molecular:269.73WAY-297174
CAS:<p>WAY-297174 is a human protein kinase CK2 inhibitor with IC50 of > 33 μM.</p>Fórmula:C11H12N2O2S2Pureza:99.53%Forma y color:SoildPeso molecular:268.36Casein kinase 1δ-IN-14
CAS:Casein kinase 1δ-IN-14 (WAY-637081) can be used to study atherosclerosis-related cardiovascular disease.Fórmula:C17H11ClN4O2Pureza:99.66%Forma y color:SolidPeso molecular:338.75Casein
CAS:Casein is a milk protein with multiple roles involved in novel drug delivery systems.Pureza:95%Forma y color:SoildCasein Kinase 2 Substrate Peptide
CAS:CK2 Substrate Peptide, C-terminus linked to EDANS, used for CK2 activity assays.Fórmula:C45H73N19O24Forma y color:SolidPeso molecular:1264.17CK1-IN-4
CK1-IN-4 (Compound 59) is an inhibitor of casein kinase CK1δ with an IC50 of 2.74 μM. It exhibits neuroprotective activity in SH-SY5Y cells treated with Ethacrynic acid.Forma y color:Odour SolidAH078
AH078 (compound 37) is a selective PROTAC degrader targeting CK1δ and CK1ε with low selectivity for CK1α. AH078 consists of a PROTAC linker (black part) Monomethyl octanoate, a target protein ligand (red part) CK1δ/CK1ε ligand-1, and an E3 ligase ligand (blue part) E3 Ligase Ligand 58. The E3 ligase ligand combined with the linker forms the conjugate E3 Ligase Ligand-linker Conjugate 163.Fórmula:C51H60F2N10O5SForma y color:SolidPeso molecular:963.15MU1742
MU1742 is a probe for CK1δ and CK1ε protein kinases [1] .Fórmula:C22H22F2N6Forma y color:SolidPeso molecular:408.45Casein kinase 1δ-IN-6
CAS:CK1δ-IN-6: potent, selective CK-1δ inhibitor, IC50 23 nM, neuroprotective, anti-inflammatory, for neurodegenerative research.Fórmula:C16H10ClF3N2OSPureza:99.87%Forma y color:SoildPeso molecular:370.78CZP-IN-1
CZP-IN-1 (compound SH-1) is an inhibitor targeting the pathogen Trypanosoma cruzi protease (CZP) without affecting cathepsin L (IC50=28 nM). This compound is applicable in Chagas disease research.Fórmula:C20H26N4O4SForma y color:SolidPeso molecular:418.51Casein kinase 1δ-IN-15
CAS:Casein kinase 1δ-IN-15, an inhibitor for casein kinase 1 (CK1δ), exhibits an IC50 of 0.045 μM [1].Fórmula:C19H17FN6OForma y color:SolidPeso molecular:364.38CK1δ/CK1ε liagnd-1
CK1δ/CK1ε ligand-1 is a ligand of CK1δ/CK1ε and can serve as a target protein ligand for the synthesis of the CK1 PROTAC degrader AH078.Fórmula:C21H20F2N6Forma y color:SolidPeso molecular:394.42
