Caseína quinasa
Las caseína quinasas son una familia de quinasas de proteínas serina/treonina que regulan varios procesos celulares, incluyendo la reparación del ADN, los ritmos circadianos y la transducción de señales. Estas quinasas están involucradas en la fosforilación de numerosas proteínas y están implicadas en enfermedades como el cáncer, los trastornos neurodegenerativos y los síndromes metabólicos. En CymitQuimica, ofrecemos una selección de inhibidores de caseína quinasa para apoyar su investigación en transducción de señales, regulación del ciclo celular y desarrollo terapéutico.
Se han encontrado 150 productos para "Caseína quinasa".
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Casein kinase 1δ-IN-6
CAS:CK1δ-IN-6: potent, selective CK-1δ inhibitor, IC50 23 nM, neuroprotective, anti-inflammatory, for neurodegenerative research.Fórmula:C16H10ClF3N2OSPureza:99.87%Forma y color:SolidPeso molecular:370.78TBCA
CAS:TBCA: selective CK2 inhibitor, IC50=110 nM, Ki=77 nM, favors CK2 over CK1, DYRK1A, and 27 other kinases.Fórmula:C9H4Br4O2Pureza:99.3%Forma y color:SolidPeso molecular:463.74Casein kinase 1δ-IN-8
CAS:Casein kinase 1δ-IN-8 is an inhibitor of casein kinase 1δ and is used to treat neurodegenerative diseases such as Alzheimer's disease type.Fórmula:C19H14FN5OSPureza:99.56%Forma y color:SolidPeso molecular:379.41Casein Kinase 2 Substrate Peptide
CAS:CK2 Substrate Peptide, C-terminus linked to EDANS, used for CK2 activity assays.Fórmula:C45H73N19O24Forma y color:SolidPeso molecular:1264.17Casein kinase 1δ-IN-14
CAS:Casein kinase 1δ-IN-14 (WAY-637081) can be used to study atherosclerosis-related cardiovascular disease.Fórmula:C17H11ClN4O2Pureza:99.66%Forma y color:SolidPeso molecular:338.75AH081
AH081 (Compound 38) is a CK1δ/ε PROTAC degrader and serves as the negative control for AH078. It maintains inhibitory activity against CK1δ/ε but lacks degradation activity due to the use of an inactive stereoisomer of the VHL ligand.Forma y color:Odour SolidCasein kinase 1δ-IN-9
CAS:Casein kinase 1δ-IN-9 is a Quinone reductase 2 inhibitor with IC50 of 0.6μM.Fórmula:C15H12ClN3Pureza:99.93%Forma y color:White SolidPeso molecular:269.73MU1742
MU1742 is a probe for CK1δ and CK1ε protein kinases [1] .Fórmula:C22H22F2N6Forma y color:SolidPeso molecular:408.45CK2-IN-15
CK2-IN-15 (Compound Biv5) is a selective and potent inhibitor of the enzyme protein kinase CK2, with an IC50 value of 51 pM. It significantly reduces the replication of SARS-CoV-2 in HEK-ACE2-TMPRSS2 and Vero cells, and also decreases viral replication in an in vitro model of human nasal epithelial cells. CK2-IN-15 holds potential for research into diseases related to β-coronavirus infections.Forma y color:Odour SolidQXG-6442
QXG-6442 is a molecular glue degrader targeting CK1α, demonstrating a degradation potency with a DC50 of 5.7 nM and a Dmax of 90%. In the MOLM-14 cell line, QXG-6442 induces antiproliferative effects.Fórmula:C21H17N5O4Forma y color:SolidPeso molecular:403.39Casein Kinase Substrates 3
CAS:Casein Kinase Substrates 3 is a substrate of casein kinase.Fórmula:C85H139N27O35SPureza:98%Forma y color:SolidPeso molecular:2131.24Casein kinase 1δ-IN-7
CAS:Casein kinase 1δ-IN-7 is a Casein kinase 1δ inhibitor for neurodegenerative diseases such as Alzheimer's disease.Fórmula:C17H14N4O2SPureza:98.02%Forma y color:SolidPeso molecular:338.38WAY-297174
CAS:WAY-297174 is a human protein kinase CK2 inhibitor with IC50 of > 33 μM.Fórmula:C11H12N2O2S2Pureza:99.53%Forma y color:SolidPeso molecular:268.36SGC-CK2-1
CAS:SGC-CK2-1, a CK2 inhibitor, is a inducer of insulin production and secretion in pancreatic β-cells.Fórmula:C20H21N7OPureza:99.41%Forma y color:SolidPeso molecular:375.43MRT00033659
CAS:MRT00033659 inhibits CK1 (IC50=0.9 μM), CHK1 (IC50=0.23 μM), activates p53, and destabilizes E2F-1; it's a pyrazolo-pyridine.Fórmula:C15H14N4OForma y color:SolidPeso molecular:266.3FPFT-2216
CAS:FPFT-2216 is a "molecular glue" compound with potential anti-tumor activity that degrades IKZF6, IKZF1, DE1D and can be used to study immune system diseases.Fórmula:C12H12N4O3SPureza:99.35% - 99.62%Forma y color:SolidPeso molecular:292.31Ref: TM-T60608
1mg92,00€5mg222,00€1mL*10mM (DMSO)236,00€10mg334,00€25mg708,00€50mg1.108,00€100mg1.783,00€200mg2.412,00€PF-5006739
CAS:PF-5006739 is a selective CK1δ/ε inhibitor for psychiatric disorder and metabolic research.Fórmula:C22H22FN7OPureza:99.96%Forma y color:SolidPeso molecular:419.45TBB
CAS:TBB (NSC-231634)(NSC-231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2).Fórmula:C6HBr4N3Pureza:98.51% - 99.51%Forma y color:SolidPeso molecular:434.708CK1-IN-1
CAS:CK1-IN-1, a CK1 inhibitor with IC50: 15nM CK1δ, 16nM CK1ε, 73nM p38σ; patent WO2015119579A1.Fórmula:C24H15F2N3Pureza:98.79%Forma y color:White SolidPeso molecular:383.39Ref: TM-T5393
1mg47,00€2mg62,00€5mg92,00€1mL*10mM (DMSO)101,00€10mg152,00€25mg289,00€50mg447,00€100mg670,00€Silmitasertib
CAS:Silmitasertib (CX-4945) is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2; Ki: 0.38 nM).Fórmula:C19H12ClN3O2Pureza:98% - 99.94%Forma y color:SolidPeso molecular:349.77Ref: TM-T2259
1mg38,00€2mg49,00€5mg80,00€1mL*10mM (DMSO)88,00€10mg118,00€25mg197,00€50mg313,00€100mg492,00€500mg1.054,00€
