Factor Xa
El factor Xa es una enzima crucial en la cascada de coagulación que convierte la protrombina en trombina, lo que lleva a la formación de coágulos sanguíneos. La inhibición del factor Xa es una estrategia terapéutica ampliamente utilizada para prevenir y tratar los trastornos tromboembólicos, como la trombosis venosa profunda, la embolia pulmonar y el accidente cerebrovascular. En CymitQuimica, ofrecemos inhibidores del factor Xa para apoyar su investigación en hematología, salud cardiovascular y terapia anticoagulante.
Se han encontrado 80 productos de "Factor Xa"
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Edoxaban
CAS:<p>Edoxaban: potent, selective FXa inhibitor; Ki 0.561 nM. Used as an oral anticoagulant for stroke prevention, also inhibits thrombin and FIXa.</p>Fórmula:C24H30ClN7O4SPureza:97.67% - 99.71%Forma y color:SolidPeso molecular:548.06Zifaxaban
CAS:<p>Zifaxaban (TY-602) is an oral selective factor Xa inhibitor with an IC50 of 11.1 nM, highly specific over other serine proteases, used in thrombosis studies.</p>Fórmula:C20H16ClN3O4SPureza:97.46% - 99.82%Forma y color:SolidPeso molecular:429.88BMS-262084
CAS:<p>BMS-262084 is a potent selective β-lactam trypsin inhibitor with therapeutic potential in the treatment of asthma.</p>Fórmula:C18H31N7O5Forma y color:SolidPeso molecular:425.48FXIa-IN-1
CAS:<p>FXIa-IN-1 is a potent β-lactam covalent heparin-derived factor XIa (fXIa) inhibitor.</p>Fórmula:C20H19F3N4O5Pureza:98%Forma y color:SolidPeso molecular:452.38Frunexian
CAS:<p>Frunexian (EP-7041) is a selective and potent inhibitor of coagulation factor XI/activated factor XI, specifically targeting XIa.</p>Fórmula:C19H26N4O4Pureza:98%Forma y color:SolidPeso molecular:374.43AS1468240
CAS:<p>AS1468240 is a factor Xa inhibitor. It has significant oral anticoagulant activity.</p>Fórmula:C25H25Cl2N5O3Forma y color:SolidPeso molecular:514.4BI-11634
CAS:<p>BI-11634 is a factor Xa inhibitor.</p>Fórmula:C22H23ClN4NaO4Pureza:98%Forma y color:SolidPeso molecular:465.89BMS-962212
CAS:<p>BMS-962212: reversible, selective FXIa blocker, well-tolerated, quick PD effect, rapid clearance, alters clotting time/activity.</p>Fórmula:C32H28ClFN8O5Pureza:98%Forma y color:SolidPeso molecular:659.07FXIa-IN-7
CAS:<p>FXIa-IN-7 is an orally available, selective and potent inhibitor of factor XIa for the study of thrombophilia.</p>Fórmula:C28H28N2O4Pureza:98.55%Forma y color:SolidPeso molecular:456.53BMS-654457
CAS:<p>BMS-654457 is a small-molecule, reversible inhibitor of factor XIa (FXIa; Kis: 0.2 and 0.42 nM for human and rabbit FXIa).</p>Fórmula:C36H37N5O4Pureza:98%Forma y color:SolidPeso molecular:603.71FXa-IN-1
CAS:<p>FXa-IN-1, an FXa blocker: IC50=3 nM, Ki=0.7 nM, orally available, long half-life, for thrombosis research.</p>Fórmula:C24H18F5N5OForma y color:SolidPeso molecular:487.42Dechloro Rivaroxaban
CAS:<p>Dechloro Rivaroxaban is a Factor Xa inhibitor that inhibits free FXa and plasminogen and fibrin-associated FXa activity in humans.</p>Fórmula:C19H19N3O5SPureza:98.63%Forma y color:SolidPeso molecular:401.44DX-9065A HCl hydrate
CAS:<p>DX-9065a: Competitive fXa/prothrombinase inhibitor; blocks proinflammatory events; Ki ~10-20 nM.</p>Fórmula:C26H39ClN4O8Pureza:98%Forma y color:SolidPeso molecular:571.06BAY 3389934
CAS:<p>BAY 3389934 is a dual inhibitor of factor IIa (factor IIa) and factor Xa (factor Xa), providing anticoagulant and organ-protective effects. It alleviates coagulopathy and organ dysfunction in baboon models of Staphylococcus aureus sepsis.</p>Fórmula:C26H30ClN5O7S2Forma y color:SolidPeso molecular:624.129RWJ-445167
CAS:<p>RWJ-445167 is a thrombin and factor Xa dual inhibitor(Ki of 4.0 nM and 230 nM, respectively), with potent antithrombotic activity.</p>Fórmula:C18H24N6O5SPureza:98%Forma y color:SolidPeso molecular:436.49FXIa-6f
CAS:<p>FXIa-6f is a high affinity, orally bioavailable macrocyclic FXIa inhibitor with antithrombotic activity in preclinical species</p>Fórmula:C31H29ClF2N4O4Forma y color:SolidPeso molecular:595.04FXIa-IN-6
CAS:<p>FXIa-IN-6: Potent, selective FXIa inhibitor (Ki=0.3 nM); strong PK with high oral bioavailability, low clearance preclinically.</p>Fórmula:C31H29ClF2N4O4Forma y color:SolidPeso molecular:595.04FXIa-IN-9
CAS:<p>FXIa-IN-9, a potent FXIa inhibitor (K i : human 0.17 nM, rabbit 0.5 nM), forms hydrogen bonds and has anticoagulant properties.</p>Fórmula:C23H18Cl2F3N9O2Forma y color:SolidPeso molecular:580.35FXIa-IN-8
<p>FXIa-IN-8: potent FXIa blocker (IC50: 14.2 nM), anti-thrombotic, low bleeding/toxicity risk.</p>Forma y color:Solid5-Chlorothiophene-2-carboxylic acid
CAS:<p>5-Chlorothiophene-2-carboxylic acid [catalog number: T66447, CAS number: 24065-33-6] is a valuable organic compound for life sciences research.</p>Fórmula:C5H3ClO2SForma y color:SolidPeso molecular:162.59
