Factor Xa
El factor Xa es una enzima crucial en la cascada de coagulación que convierte la protrombina en trombina, lo que lleva a la formación de coágulos sanguíneos. La inhibición del factor Xa es una estrategia terapéutica ampliamente utilizada para prevenir y tratar los trastornos tromboembólicos, como la trombosis venosa profunda, la embolia pulmonar y el accidente cerebrovascular. En CymitQuimica, ofrecemos inhibidores del factor Xa para apoyar su investigación en hematología, salud cardiovascular y terapia anticoagulante.
Se han encontrado 90 productos para "Factor Xa".
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D-Leu-Pro-Arg-Rh110-D-Pro acetate
D-Leu-Pro-Arg-Rh110-D-Pro acetate is a substrate for Factor XaI (FXIa) with binding affinity. This compound is formed by linking Rhodamine 110 to a peptide chain via a cleavable bond. The cleavage of this bond enhances the intensity of the fluorophore. D-Leu-Pro-Arg-Rh110-D-Pro acetate can be used to detect FXIa activity.Fórmula:C42H51N9O7·xC2H4O2FXIIa-IN-4
FXIIa-IN-4 (compound 22) is a potent and selective human FXIIa inhibitor, exhibiting IC50 values of 0.032 μM for FXIIa, 0.30 μM for thrombin, and >50 μM for FXIa. It is utilized in anticoagulant research.Fórmula:C11H9FN4O3Forma y color:SolidPeso molecular:264.06587FXIa-IN-15
CAS:FXIa-IN-15 (Compound (S)-10h) is an inhibitor of factor XIa (FXIa) and plasma kallikrein (PKa) with IC50 values of 0.38 nM and 59.2 nM, respectively. It exhibits anticoagulant properties by prolonging the 50% activated partial thromboplastin time (aPTT) with an EC1.5X of 0.55 μM.Fórmula:C32H23ClF3N7O4Forma y color:SolidPeso molecular:662.02D-Pro-Phe-Arg-Chloromethylketone
CAS:D-Pro-Phe-Arg-Chloromethylketone, an inhibitor of coagulation factor XII and plasma kallikrein, is significant in the regulation of thrombosis and inflammationFórmula:C21H31ClN6O3Pureza:98%Forma y color:SolidPeso molecular:450.96Asundexian
CAS:Asundexian (BAY-2433334) is a potent and orally active inhibitor of the coagulation factor FXIa that directly and reversibly binds to the active site of FXIa,Fórmula:C26H21ClF4N6O4Pureza:99.89% - 99.90%Forma y color:SolidPeso molecular:592.929Edoxaban impurity 6
CAS:Edoxaban impurity 6 is a byproduct of the anticoagulant Edoxaban, a potent oral factor Xa inhibitor with Kis of 0.561 nM. Used to prevent stroke.Fórmula:C16H22ClN5O3Forma y color:SolidPeso molecular:367.83Methoxycarbonyl-D-Nle-Gly-Arg-pNA
CAS:Methoxycarbonyl-D-Nle-Gly-Arg-pNA is a synthetic trypsin substrate utilized for coagulation factors IXa (FIXa) and Xa (FXa), as evidenced by studies [1] [2] [3Fórmula:C22H34N8O7Forma y color:SolidPeso molecular:522.55FXIIa-IN-1 HCl
CAS:FXIIa-IN-1 HCl is a selective inhibitor of Factor XIIa,and can be used to study thrombosis and inflammation induced by artificial surfaces.Fórmula:C21H17ClN2O6Pureza:99.61%Forma y color:SolidPeso molecular:428.82Canine Factor Xa
CanineFactor Xa is derived from purified Canine Factor X through activation by Russell's Viper Venom, after which the venom is removed.Forma y color:Odour SolidEdoxaban Isomer
CAS:Edoxaban Isomer is an impurity of Edoxaban, which is a novel inhibitor of factor Xa.Fórmula:C24H30ClN7O4SForma y color:SolidPeso molecular:548.057Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride
CAS:Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride is a chromogenic substrate specifically designed for factor Xa.Fórmula:C34H53ClN10O10Peso molecular:797.299Betrixaban-D6
CAS:Betrixaban D6 is a deuterium-labeled Betrixaban. Betrixaban is a selective and orally efficacious FXa inhibitor.Fórmula:C23H22ClN5O3Pureza:98%Forma y color:SolidPeso molecular:457.942FaX-IN-1
CAS:Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl) compound inhibits coagulation factor Xa, useful for thrombotic conditions study.Fórmula:C27H28N4O5Pureza:99.5%Forma y color:SolidPeso molecular:488.535Apixaban 13C,D3
CAS:Apixaban 13C,d3 is a deuterium labeling of Apixaban for isotopic tracing. Apixaban 13C,d3 is a selective inhibitor of coagulation factor XaFórmula:C25H25N5O4Pureza:98%Forma y color:White SolidPeso molecular:463.5082Darexaban
CAS:Darexaban (YM-150) selectively inhibits Factor Xa, reducing clotting and risk of heart/stroke events.Fórmula:C27H30N4O4Pureza:98.33%Forma y color:White SolidPeso molecular:474.5515Betrixaban hydrochloride
Betrixaban hydrochloride(330942-05-7(free base)) (PRT054021 hydrochloride) is a potent, selective, and orally efficacious factor Xa (fXa) inhibitor (IC50: 1.5Fórmula:C23H23Cl2N5O3Pureza:99.54%Forma y color:Yellow SolidPeso molecular:488.36Enoxaparin sodium
CAS:Enoxaparin, a low-weight heparin approved by FDA for STEMI, enhances antithrombin and prevents clotting by inhibiting factors XIa, IXa, Xa, IIa.Fórmula:C42H59N3Na4O35S2Pureza:98%Forma y color:White SolidPeso molecular:1322Edoxaban Tosylate Monohydrate
CAS:Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.Fórmula:C31H40ClN7O8S2Pureza:99.86% - 99.91%Forma y color:SolidPeso molecular:738.274Fondaparinux sodium
CAS:Fondaparinux sodium (SR-90107A) is an antithrombin-dependent factor Xa inhibitor with antithrombotic activity.Fórmula:C31H43N3Na10O49S8Pureza:98% - >99.99%Forma y color:SolidPeso molecular:1728.082BISMUTH SUBGALLATE
CAS:Bismuth subgallate (Dermatol Puder) is an astringent and antiseptic and is applied to skin diseases such as eczema.Fórmula:C7H5BiO6Pureza:98.7%Forma y color:White SolidPeso molecular:394.09
